Dynamics of neuronal interactions in monkey cortex in relation to behavioural events. Vaadia, E., Haalman, I., Abeles, M., Bergman, H., Prut, Y., Slovin, H., & Aertsen, A. Nature, 373:515-518, February, 1995.
abstract   bibtex   
It is possible that brain cortical function is mediated by dynamic modulation of coherent firing in groups of neurons. Indeed, a correlation of firing between cortical neurons, seen following sensory stimuli or during motor behaviour, has been described(1-5). However, the time course of modifications of correlation in relation to behaviour was not evaluated systematically. Here we show that correlated firing between single neurons, recorded simultaneously in the frontal cortex of monkeys performing a behavioural task, evolves within a fraction of a second, and in systematic relation to behavioural events. Moreover, the dynamic patterns of correlation depend on the distance between neurons, and can emerge even without modulation of the firing rates. These findings support the notion that neurons can associate rapidly into a functional group in order to perform a computational task, at the same time becoming dissociated from concurrently activated competing groups. Thus, they call for a revision of prevailing models of neural coding that rely solely on single neuron firing rates(6-8).
@article{ Vaadia_etal95,
  author = {Vaadia, E. and Haalman, I. and Abeles, M. and Bergman, H. and Prut,
	Y. and Slovin, H. and Aertsen, A.},
  title = {Dynamics of neuronal interactions in monkey cortex in relation to
	behavioural events},
  journal = {Nature},
  year = {1995},
  volume = {373},
  pages = {515-518},
  month = {February},
  abstract = { It is possible that brain cortical function is mediated by dynamic
	modulation of coherent firing in groups of neurons. Indeed, a correlation
	of firing between cortical neurons, seen following sensory stimuli
	or during motor behaviour, has been described(1-5). However, the
	time course of modifications of correlation in relation to behaviour
	was not evaluated systematically. Here we show that correlated firing
	between single neurons, recorded simultaneously in the frontal cortex
	of monkeys performing a behavioural task, evolves within a fraction
	of a second, and in systematic relation to behavioural events. Moreover,
	the dynamic patterns of correlation depend on the distance between
	neurons, and can emerge even without modulation of the firing rates.
	These findings support the notion that neurons can associate rapidly
	into a functional group in order to perform a computational task,
	at the same time becoming dissociated from concurrently activated
	competing groups. Thus, they call for a revision of prevailing models
	of neural coding that rely solely on single neuron firing rates(6-8).},
  en_number = {3.6.7:11 }
}
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