Gastroesophageal Reflux, as Measured By 24-Hour pH Monitoring, in 509 Healthy Infants Screened for Risk of Sudden Infant Death Syndrome. Vandenplas, Y., Goyvaerts, H., Helven, R., & Sacre, L. Pediatrics, 88(4):834, October, 1991. ![Gastroesophageal Reflux, as Measured By 24-Hour pH Monitoring, in 509 Healthy Infants Screened for Risk of Sudden Infant Death Syndrome. [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper abstract bibtex Abstract. Continuous long-term esophageal pH monitoring has become the preferred test to quantify acid gastroesophageal reflux. Because reflux to a limited extent is physiologic, the determination of optimal thresholds to separate normal from abnormal reflux is mandatory. Esophageal pH was measured during 24 hours in 509 healthy thriving infants, aged 3 days to 1 year, using a glass microelectrode with an external reference electrode connected to a portable recorder. Percentiles of the four parameters studied (reflux index or percent of the investigation time with a pH \textless 4, number of episodes with a pH \textless 4 during 24 hours, number of episodes lasting \textgreater5 minutes, the duration of the longest episode (in minutes)) are presented. A percentile curve of the reflux index regarding the age distribution shows that the normal range for the reflux index during the first 12 months of life is about 10% (95 percentile), decreasing from 13% at birth to 8% at 12 months. Application of an age-related percentile curve offers a closeto-reality possibility of data interpretation and illustrates that there is inevitably an overlap of data between normal and abnormal populations, because reflux is a phenomenon occurring to some extent in every human being. [ABSTRACT FROM AUTHOR]
@article{vandenplas_gastroesophageal_1991,
title = {Gastroesophageal {Reflux}, as {Measured} {By} 24-{Hour} {pH} {Monitoring}, in 509 {Healthy} {Infants} {Screened} for {Risk} of {Sudden} {Infant} {Death} {Syndrome}.},
volume = {88},
issn = {00314005},
url = {https://search.ebscohost.com/login.aspx?direct=true&AuthType=ip,uid&db=pbh&AN=4743808&site=ehost-live},
abstract = {Abstract. Continuous long-term esophageal pH monitoring has become the preferred test to quantify acid gastroesophageal reflux. Because reflux to a limited extent is physiologic, the determination of optimal thresholds to separate normal from abnormal reflux is mandatory. Esophageal pH was measured during 24 hours in 509 healthy thriving infants, aged 3 days to 1 year, using a glass microelectrode with an external reference electrode connected to a portable recorder. Percentiles of the four parameters studied (reflux index or percent of the investigation time with a pH {\textless} 4, number of episodes with a pH {\textless} 4 during 24 hours, number of episodes lasting {\textgreater}5 minutes, the duration of the longest episode (in minutes)) are presented. A percentile curve of the reflux index regarding the age distribution shows that the normal range for the reflux index during the first 12 months of life is about 10\% (95 percentile), decreasing from 13\% at birth to 8\% at 12 months. Application of an age-related percentile curve offers a closeto-reality possibility of data interpretation and illustrates that there is inevitably an overlap of data between normal and abnormal populations, because reflux is a phenomenon occurring to some extent in every human being. [ABSTRACT FROM AUTHOR]},
number = {4},
journal = {Pediatrics},
author = {Vandenplas, Yvan and Goyvaerts, Harry and Helven, Rudy and Sacre, Liliane},
month = oct,
year = {1991},
keywords = {GASTROESOPHAGEAL reflux, SUDDEN infant death syndrome},
pages = {834},
}
Downloads: 0
{"_id":"FQxg8hXSwTX4jPaxn","bibbaseid":"vandenplas-goyvaerts-helven-sacre-gastroesophagealrefluxasmeasuredby24hourphmonitoringin509healthyinfantsscreenedforriskofsuddeninfantdeathsyndrome-1991","author_short":["Vandenplas, Y.","Goyvaerts, H.","Helven, R.","Sacre, L."],"bibdata":{"bibtype":"article","type":"article","title":"Gastroesophageal Reflux, as Measured By 24-Hour pH Monitoring, in 509 Healthy Infants Screened for Risk of Sudden Infant Death Syndrome.","volume":"88","issn":"00314005","url":"https://search.ebscohost.com/login.aspx?direct=true&AuthType=ip,uid&db=pbh&AN=4743808&site=ehost-live","abstract":"Abstract. Continuous long-term esophageal pH monitoring has become the preferred test to quantify acid gastroesophageal reflux. Because reflux to a limited extent is physiologic, the determination of optimal thresholds to separate normal from abnormal reflux is mandatory. Esophageal pH was measured during 24 hours in 509 healthy thriving infants, aged 3 days to 1 year, using a glass microelectrode with an external reference electrode connected to a portable recorder. Percentiles of the four parameters studied (reflux index or percent of the investigation time with a pH \\textless 4, number of episodes with a pH \\textless 4 during 24 hours, number of episodes lasting \\textgreater5 minutes, the duration of the longest episode (in minutes)) are presented. A percentile curve of the reflux index regarding the age distribution shows that the normal range for the reflux index during the first 12 months of life is about 10% (95 percentile), decreasing from 13% at birth to 8% at 12 months. Application of an age-related percentile curve offers a closeto-reality possibility of data interpretation and illustrates that there is inevitably an overlap of data between normal and abnormal populations, because reflux is a phenomenon occurring to some extent in every human being. [ABSTRACT FROM AUTHOR]","number":"4","journal":"Pediatrics","author":[{"propositions":[],"lastnames":["Vandenplas"],"firstnames":["Yvan"],"suffixes":[]},{"propositions":[],"lastnames":["Goyvaerts"],"firstnames":["Harry"],"suffixes":[]},{"propositions":[],"lastnames":["Helven"],"firstnames":["Rudy"],"suffixes":[]},{"propositions":[],"lastnames":["Sacre"],"firstnames":["Liliane"],"suffixes":[]}],"month":"October","year":"1991","keywords":"GASTROESOPHAGEAL reflux, SUDDEN infant death syndrome","pages":"834","bibtex":"@article{vandenplas_gastroesophageal_1991,\n\ttitle = {Gastroesophageal {Reflux}, as {Measured} {By} 24-{Hour} {pH} {Monitoring}, in 509 {Healthy} {Infants} {Screened} for {Risk} of {Sudden} {Infant} {Death} {Syndrome}.},\n\tvolume = {88},\n\tissn = {00314005},\n\turl = {https://search.ebscohost.com/login.aspx?direct=true&AuthType=ip,uid&db=pbh&AN=4743808&site=ehost-live},\n\tabstract = {Abstract. Continuous long-term esophageal pH monitoring has become the preferred test to quantify acid gastroesophageal reflux. Because reflux to a limited extent is physiologic, the determination of optimal thresholds to separate normal from abnormal reflux is mandatory. Esophageal pH was measured during 24 hours in 509 healthy thriving infants, aged 3 days to 1 year, using a glass microelectrode with an external reference electrode connected to a portable recorder. Percentiles of the four parameters studied (reflux index or percent of the investigation time with a pH {\\textless} 4, number of episodes with a pH {\\textless} 4 during 24 hours, number of episodes lasting {\\textgreater}5 minutes, the duration of the longest episode (in minutes)) are presented. A percentile curve of the reflux index regarding the age distribution shows that the normal range for the reflux index during the first 12 months of life is about 10\\% (95 percentile), decreasing from 13\\% at birth to 8\\% at 12 months. Application of an age-related percentile curve offers a closeto-reality possibility of data interpretation and illustrates that there is inevitably an overlap of data between normal and abnormal populations, because reflux is a phenomenon occurring to some extent in every human being. [ABSTRACT FROM AUTHOR]},\n\tnumber = {4},\n\tjournal = {Pediatrics},\n\tauthor = {Vandenplas, Yvan and Goyvaerts, Harry and Helven, Rudy and Sacre, Liliane},\n\tmonth = oct,\n\tyear = {1991},\n\tkeywords = {GASTROESOPHAGEAL reflux, SUDDEN infant death syndrome},\n\tpages = {834},\n}\n\n\n\n","author_short":["Vandenplas, Y.","Goyvaerts, H.","Helven, R.","Sacre, L."],"key":"vandenplas_gastroesophageal_1991","id":"vandenplas_gastroesophageal_1991","bibbaseid":"vandenplas-goyvaerts-helven-sacre-gastroesophagealrefluxasmeasuredby24hourphmonitoringin509healthyinfantsscreenedforriskofsuddeninfantdeathsyndrome-1991","role":"author","urls":{"Paper":"https://search.ebscohost.com/login.aspx?direct=true&AuthType=ip,uid&db=pbh&AN=4743808&site=ehost-live"},"keyword":["GASTROESOPHAGEAL reflux","SUDDEN infant death syndrome"],"metadata":{"authorlinks":{}},"html":""},"bibtype":"article","biburl":"https://bibbase.org/zotero/saurabhr","dataSources":["nxjWwW7fWbb5tfpKz"],"keywords":["gastroesophageal reflux","sudden infant death syndrome"],"search_terms":["gastroesophageal","reflux","measured","hour","monitoring","509","healthy","infants","screened","risk","sudden","infant","death","syndrome","vandenplas","goyvaerts","helven","sacre"],"title":"Gastroesophageal Reflux, as Measured By 24-Hour pH Monitoring, in 509 Healthy Infants Screened for Risk of Sudden Infant Death Syndrome.","year":1991}