@article{RN190,
   author = {van der Kruijs, S. J. and Vonck, K. E. and Langereis, G. R. and Feijs, L. M. and Bodde, N. M. and Lazeron, R. H. and Carrette, E. and Boon, P. A. and Backes, W. H. and Jansen, J. F. and Aldenkamp, A. P. and Cluitmans, P. J.},
   title = {Autonomic nervous system functioning associated with psychogenic nonepileptic seizures: Analysis of heart rate variability},
   journal = {Epilepsy Behav},
   volume = {54},
   pages = {14-9},
   note = {van der Kruijs, Sylvie J M
Vonck, Kristl E J
Langereis, Geert R
Feijs, Loe M G
Bodde, Nynke M G
Lazeron, Richard H C
Carrette, Evelien
Boon, Paul A J M
Backes, Walter H
Jansen, Jacobus F A
Aldenkamp, Albert P
Cluitmans, Pierre J M
eng
2015/11/30 06:00
Epilepsy Behav. 2016 Jan;54:14-9. doi: 10.1016/j.yebeh.2015.10.014. Epub 2015 Nov 25.},
   abstract = {OBJECTIVE: Psychogenic nonepileptic seizures (PNESs) resemble epileptic seizures but originate from psychogenic rather than organic causes. Patients with PNESs are often unable or unwilling to reflect on underlying emotions. To gain more insight into the internal states of patients during PNES episodes, this study explored the time course of heart rate variability (HRV) measures, which provide information about autonomic nervous system functioning and arousal. METHODS: Heart rate variability measures were extracted from double-lead electrocardiography data collected during 1-7days of video-electroencephalography monitoring of 20 patients with PNESs, in whom a total number of 118 PNESs was recorded. Heart rate (HR) and HRV measures in time and frequency domains (standard deviation of average beat-to-beat intervals (SDANN), root mean square of successive differences (RMSSD), high-frequency (HF) power, low-frequency (LF) power, and very low-frequency (VLF) power) were averaged over consecutive five-minute intervals. Additionally, quantitative analyses of Poincare plot parameters (SD1, SD2, and SD1/SD2 ratio) were performed. RESULTS: In the five-minute interval before PNES, HR significantly (p<0.05) increased (d=2.5), whereas SDANN (d=-0.03) and VLF power (d=-0.05) significantly decreased. During PNES, significant increases in HF power (d=0.0006), SD1 (d=0.031), and SD2 (d=0.016) were observed. In the five-minute interval immediately following PNES, SDANN (d=0.046) and VLF power (d=0.073) significantly increased, and HR (d=-5.1) and SD1/SD2 ratio (d=-0.14) decreased, compared to the interval preceding PNES. CONCLUSION: The results suggest that PNES episodes are preceded by increased sympathetic functioning, which is followed by an increase in parasympathetic functioning during and after PNES. Future research needs to identify the exact nature of the increased arousal that precedes PNES.},
   keywords = {Adult
Arousal/physiology
Autonomic Nervous System/*physiopathology
Electrocardiography
Emotions/physiology
Female
Heart Rate/*physiology
Humans
Male
Middle Aged
Psychophysiologic Disorders/*physiopathology/psychology
Seizures/*physiopathology/psychology
Young Adult
Autonomic nervous system
Conversion disorder
Heart rate variability
Psychogenic nonepileptic seizures
Vagal tone},
   ISSN = {1525-5069 (Electronic)
1525-5050 (Linking)},
   DOI = {10.1016/j.yebeh.2015.10.014},
   url = {http://www.ncbi.nlm.nih.gov/pubmed/26615481
https://www.epilepsybehavior.com/article/S1525-5050(15)00574-0/fulltext
https://www.epilepsybehavior.com/article/S1525-5050(15)00574-0/pdf},
   year = {2016},
   type = {Journal Article}
}

{"_id":"qmqKAoHnQjtqQnBJH","bibbaseid":"vanderkruijs-vonck-langereis-feijs-bodde-lazeron-carrette-boon-etal-autonomicnervoussystemfunctioningassociatedwithpsychogenicnonepilepticseizuresanalysisofheartratevariability-2016","downloads":0,"creationDate":"2017-09-02T18:10:13.467Z","title":"Autonomic nervous system functioning associated with psychogenic nonepileptic seizures: Analysis of heart rate variability","author_short":["van der Kruijs, S. J.","Vonck, K. E.","Langereis, G. R.","Feijs, L. M.","Bodde, N. M.","Lazeron, R. H.","Carrette, E.","Boon, P. A.","Backes, W. H.","Jansen, J. F.","Aldenkamp, A. P.","Cluitmans, P. J."],"year":2016,"bibtype":"article","biburl":"https://raw.githubusercontent.com/jansenjfa1/bibbase.github.io/master/jansenjfa.bib","bibdata":{"bibtype":"article","type":"Journal Article","author":[{"propositions":["van","der"],"lastnames":["Kruijs"],"firstnames":["S.","J."],"suffixes":[]},{"propositions":[],"lastnames":["Vonck"],"firstnames":["K.","E."],"suffixes":[]},{"propositions":[],"lastnames":["Langereis"],"firstnames":["G.","R."],"suffixes":[]},{"propositions":[],"lastnames":["Feijs"],"firstnames":["L.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Bodde"],"firstnames":["N.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Lazeron"],"firstnames":["R.","H."],"suffixes":[]},{"propositions":[],"lastnames":["Carrette"],"firstnames":["E."],"suffixes":[]},{"propositions":[],"lastnames":["Boon"],"firstnames":["P.","A."],"suffixes":[]},{"propositions":[],"lastnames":["Backes"],"firstnames":["W.","H."],"suffixes":[]},{"propositions":[],"lastnames":["Jansen"],"firstnames":["J.","F."],"suffixes":[]},{"propositions":[],"lastnames":["Aldenkamp"],"firstnames":["A.","P."],"suffixes":[]},{"propositions":[],"lastnames":["Cluitmans"],"firstnames":["P.","J."],"suffixes":[]}],"title":"Autonomic nervous system functioning associated with psychogenic nonepileptic seizures: Analysis of heart rate variability","journal":"Epilepsy Behav","volume":"54","pages":"14-9","note":"van der Kruijs, Sylvie J M Vonck, Kristl E J Langereis, Geert R Feijs, Loe M G Bodde, Nynke M G Lazeron, Richard H C Carrette, Evelien Boon, Paul A J M Backes, Walter H Jansen, Jacobus F A Aldenkamp, Albert P Cluitmans, Pierre J M eng 2015/11/30 06:00 Epilepsy Behav. 2016 Jan;54:14-9. doi: 10.1016/j.yebeh.2015.10.014. Epub 2015 Nov 25.","abstract":"OBJECTIVE: Psychogenic nonepileptic seizures (PNESs) resemble epileptic seizures but originate from psychogenic rather than organic causes. Patients with PNESs are often unable or unwilling to reflect on underlying emotions. To gain more insight into the internal states of patients during PNES episodes, this study explored the time course of heart rate variability (HRV) measures, which provide information about autonomic nervous system functioning and arousal. METHODS: Heart rate variability measures were extracted from double-lead electrocardiography data collected during 1-7days of video-electroencephalography monitoring of 20 patients with PNESs, in whom a total number of 118 PNESs was recorded. Heart rate (HR) and HRV measures in time and frequency domains (standard deviation of average beat-to-beat intervals (SDANN), root mean square of successive differences (RMSSD), high-frequency (HF) power, low-frequency (LF) power, and very low-frequency (VLF) power) were averaged over consecutive five-minute intervals. Additionally, quantitative analyses of Poincare plot parameters (SD1, SD2, and SD1/SD2 ratio) were performed. RESULTS: In the five-minute interval before PNES, HR significantly (p<0.05) increased (d=2.5), whereas SDANN (d=-0.03) and VLF power (d=-0.05) significantly decreased. During PNES, significant increases in HF power (d=0.0006), SD1 (d=0.031), and SD2 (d=0.016) were observed. In the five-minute interval immediately following PNES, SDANN (d=0.046) and VLF power (d=0.073) significantly increased, and HR (d=-5.1) and SD1/SD2 ratio (d=-0.14) decreased, compared to the interval preceding PNES. CONCLUSION: The results suggest that PNES episodes are preceded by increased sympathetic functioning, which is followed by an increase in parasympathetic functioning during and after PNES. Future research needs to identify the exact nature of the increased arousal that precedes PNES.","keywords":"Adult Arousal/physiology Autonomic Nervous System/*physiopathology Electrocardiography Emotions/physiology Female Heart Rate/*physiology Humans Male Middle Aged Psychophysiologic Disorders/*physiopathology/psychology Seizures/*physiopathology/psychology Young Adult Autonomic nervous system Conversion disorder Heart rate variability Psychogenic nonepileptic seizures Vagal tone","issn":"1525-5069 (Electronic) 1525-5050 (Linking)","doi":"10.1016/j.yebeh.2015.10.014","url":"http://www.ncbi.nlm.nih.gov/pubmed/26615481 https://www.epilepsybehavior.com/article/S1525-5050(15)00574-0/fulltext https://www.epilepsybehavior.com/article/S1525-5050(15)00574-0/pdf","year":"2016","bibtex":"@article{RN190,\n author = {van der Kruijs, S. J. and Vonck, K. E. and Langereis, G. R. and Feijs, L. M. and Bodde, N. M. and Lazeron, R. H. and Carrette, E. and Boon, P. A. and Backes, W. H. and Jansen, J. F. and Aldenkamp, A. P. and Cluitmans, P. J.},\n title = {Autonomic nervous system functioning associated with psychogenic nonepileptic seizures: Analysis of heart rate variability},\n journal = {Epilepsy Behav},\n volume = {54},\n pages = {14-9},\n note = {van der Kruijs, Sylvie J M\nVonck, Kristl E J\nLangereis, Geert R\nFeijs, Loe M G\nBodde, Nynke M G\nLazeron, Richard H C\nCarrette, Evelien\nBoon, Paul A J M\nBackes, Walter H\nJansen, Jacobus F A\nAldenkamp, Albert P\nCluitmans, Pierre J M\neng\n2015/11/30 06:00\nEpilepsy Behav. 2016 Jan;54:14-9. doi: 10.1016/j.yebeh.2015.10.014. Epub 2015 Nov 25.},\n abstract = {OBJECTIVE: Psychogenic nonepileptic seizures (PNESs) resemble epileptic seizures but originate from psychogenic rather than organic causes. Patients with PNESs are often unable or unwilling to reflect on underlying emotions. To gain more insight into the internal states of patients during PNES episodes, this study explored the time course of heart rate variability (HRV) measures, which provide information about autonomic nervous system functioning and arousal. METHODS: Heart rate variability measures were extracted from double-lead electrocardiography data collected during 1-7days of video-electroencephalography monitoring of 20 patients with PNESs, in whom a total number of 118 PNESs was recorded. Heart rate (HR) and HRV measures in time and frequency domains (standard deviation of average beat-to-beat intervals (SDANN), root mean square of successive differences (RMSSD), high-frequency (HF) power, low-frequency (LF) power, and very low-frequency (VLF) power) were averaged over consecutive five-minute intervals. Additionally, quantitative analyses of Poincare plot parameters (SD1, SD2, and SD1/SD2 ratio) were performed. RESULTS: In the five-minute interval before PNES, HR significantly (p<0.05) increased (d=2.5), whereas SDANN (d=-0.03) and VLF power (d=-0.05) significantly decreased. During PNES, significant increases in HF power (d=0.0006), SD1 (d=0.031), and SD2 (d=0.016) were observed. In the five-minute interval immediately following PNES, SDANN (d=0.046) and VLF power (d=0.073) significantly increased, and HR (d=-5.1) and SD1/SD2 ratio (d=-0.14) decreased, compared to the interval preceding PNES. CONCLUSION: The results suggest that PNES episodes are preceded by increased sympathetic functioning, which is followed by an increase in parasympathetic functioning during and after PNES. Future research needs to identify the exact nature of the increased arousal that precedes PNES.},\n keywords = {Adult\nArousal/physiology\nAutonomic Nervous System/*physiopathology\nElectrocardiography\nEmotions/physiology\nFemale\nHeart Rate/*physiology\nHumans\nMale\nMiddle Aged\nPsychophysiologic Disorders/*physiopathology/psychology\nSeizures/*physiopathology/psychology\nYoung Adult\nAutonomic nervous system\nConversion disorder\nHeart rate variability\nPsychogenic nonepileptic seizures\nVagal tone},\n ISSN = {1525-5069 (Electronic)\n1525-5050 (Linking)},\n DOI = {10.1016/j.yebeh.2015.10.014},\n url = {http://www.ncbi.nlm.nih.gov/pubmed/26615481\nhttps://www.epilepsybehavior.com/article/S1525-5050(15)00574-0/fulltext\nhttps://www.epilepsybehavior.com/article/S1525-5050(15)00574-0/pdf},\n year = {2016},\n type = {Journal Article}\n}\n\n","author_short":["van der Kruijs, S. J.","Vonck, K. E.","Langereis, G. R.","Feijs, L. M.","Bodde, N. M.","Lazeron, R. H.","Carrette, E.","Boon, P. 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