Treatment of attention-deficit/hyperactivity disorder in children. Predictors of treatment outcome. van der Oord, S., Prins, P J M, Oosterlaan, J, & Emmelkamp, P M G European child & adolescent psychiatry, 17(2):73–81, March, 2008. Paper abstract bibtex OBJECTIVE: The present study investigated the predictive power of anxiety, IQ, severity of ADHD and parental depression on the outcome of treatment in children with ADHD. METHOD: Fifty children with ADHD (ages 8-12) were randomized to a 10-week treatment of methylphenidate or to a treatment of methylphenidate combined with multimodal behavior therapy. Prior to treatment predictors were assessed. Outcome was assessed separately for parents and teachers on a composite measure of inattentive, hyperactive, oppositional- and conduct disorder symptoms. RESULTS: There was neither a significant difference between the two treatments at baseline nor did treatment condition predict outcome. Therefore the data were collapsed across the two treatments. A combination of anxiety and IQ predicted teacher-rated outcome, explaining 18% of the variance. Higher anxiety and higher IQ's indicated better treatment outcome. There were no significant predictors of the parent-rated outcome. CONCLUSION: This study showed a small but significant predictive effect of IQ and anxiety on treatment outcome in children with ADHD. CLINICAL IMPLICATIONS: This study supports the idea that for the treatment of ADHD children with comorbid anxiety and higher IQ respond better to the two most used treatments for ADHD.
@article{van_der_oord_treatment_2008,
title = {Treatment of attention-deficit/hyperactivity disorder in children. {Predictors} of treatment outcome.},
volume = {17},
issn = {1018-8827},
url = {http://www.ncbi.nlm.nih.gov/pubmed/17876505},
abstract = {OBJECTIVE: The present study investigated the predictive power of anxiety, IQ, severity of ADHD and parental depression on the outcome of treatment in children with ADHD. METHOD: Fifty children with ADHD (ages 8-12) were randomized to a 10-week treatment of methylphenidate or to a treatment of methylphenidate combined with multimodal behavior therapy. Prior to treatment predictors were assessed. Outcome was assessed separately for parents and teachers on a composite measure of inattentive, hyperactive, oppositional- and conduct disorder symptoms. RESULTS: There was neither a significant difference between the two treatments at baseline nor did treatment condition predict outcome. Therefore the data were collapsed across the two treatments. A combination of anxiety and IQ predicted teacher-rated outcome, explaining 18\% of the variance. Higher anxiety and higher IQ's indicated better treatment outcome. There were no significant predictors of the parent-rated outcome. CONCLUSION: This study showed a small but significant predictive effect of IQ and anxiety on treatment outcome in children with ADHD. CLINICAL IMPLICATIONS: This study supports the idea that for the treatment of ADHD children with comorbid anxiety and higher IQ respond better to the two most used treatments for ADHD.},
number = {2},
urldate = {2014-05-23},
journal = {European child \& adolescent psychiatry},
author = {van der Oord, Saskia and Prins, P J M and Oosterlaan, J and Emmelkamp, P M G},
month = mar,
year = {2008},
keywords = {Attention Deficit Disorder with Hyperactivity, Attention Deficit Disorder with Hyperactivity: dia, Attention Deficit Disorder with Hyperactivity: dru, Attention Deficit Disorder with Hyperactivity: psy, Behavior Therapy, Central Nervous System Stimulants, Central Nervous System Stimulants: therapeutic use, Child, Female, Humans, Male, Methylphenidate, Methylphenidate: therapeutic use, Predictive Value of Tests, Prospective Studies, Treatment Outcome},
pages = {73--81},
}
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Outcome was assessed separately for parents and teachers on a composite measure of inattentive, hyperactive, oppositional- and conduct disorder symptoms. RESULTS: There was neither a significant difference between the two treatments at baseline nor did treatment condition predict outcome. Therefore the data were collapsed across the two treatments. A combination of anxiety and IQ predicted teacher-rated outcome, explaining 18% of the variance. Higher anxiety and higher IQ's indicated better treatment outcome. There were no significant predictors of the parent-rated outcome. CONCLUSION: This study showed a small but significant predictive effect of IQ and anxiety on treatment outcome in children with ADHD. CLINICAL IMPLICATIONS: This study supports the idea that for the treatment of ADHD children with comorbid anxiety and higher IQ respond better to the two most used treatments for ADHD.","number":"2","urldate":"2014-05-23","journal":"European child & adolescent psychiatry","author":[{"propositions":["van","der"],"lastnames":["Oord"],"firstnames":["Saskia"],"suffixes":[]},{"propositions":[],"lastnames":["Prins"],"firstnames":["P","J","M"],"suffixes":[]},{"propositions":[],"lastnames":["Oosterlaan"],"firstnames":["J"],"suffixes":[]},{"propositions":[],"lastnames":["Emmelkamp"],"firstnames":["P","M","G"],"suffixes":[]}],"month":"March","year":"2008","keywords":"Attention Deficit Disorder with Hyperactivity, Attention Deficit Disorder with Hyperactivity: dia, Attention Deficit Disorder with Hyperactivity: dru, Attention Deficit Disorder with Hyperactivity: psy, Behavior Therapy, Central Nervous System Stimulants, Central Nervous System Stimulants: therapeutic use, Child, Female, Humans, Male, Methylphenidate, Methylphenidate: therapeutic use, Predictive Value of Tests, Prospective Studies, Treatment Outcome","pages":"73–81","bibtex":"@article{van_der_oord_treatment_2008,\n\ttitle = {Treatment of attention-deficit/hyperactivity disorder in children. {Predictors} of treatment outcome.},\n\tvolume = {17},\n\tissn = {1018-8827},\n\turl = {http://www.ncbi.nlm.nih.gov/pubmed/17876505},\n\tabstract = {OBJECTIVE: The present study investigated the predictive power of anxiety, IQ, severity of ADHD and parental depression on the outcome of treatment in children with ADHD. 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