HISTONE DEACETYLASE 9 stimulates auxin-dependent thermomorphogenesis in <i>Arabidopsis thaliana</i> by mediating H2A.Z depletion. van der Woude, L. C., Perrella, G., Snoek, B. L., van Hoogdalem, M., Novák, O., van Verk, M. C., van Kooten, H. N., Zorn, L. E., Tonckens, R., Dongus, J. A., Praat, M., Stouten, E. A., Proveniers, M. C. G., Vellutini, E., Patitaki, E., Shapulatov, U., Kohlen, W., Balasubramanian, S., Ljung, K., van der Krol, A. R., Smeekens, S., Kaiserli, E., & van Zanten, M. Proceedings of the National Academy of Sciences, 116(50):25343–25354, December, 2019. ![HISTONE DEACETYLASE 9 stimulates auxin-dependent thermomorphogenesis in <i>Arabidopsis thaliana</i> by mediating H2A.Z depletion [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Many plant species respond to unfavorable high ambient temperatures by adjusting their vegetative body plan to facilitate cooling. This process is known as thermomorphogenesis and is induced by the phytohormone auxin. Here, we demonstrate that the chromatin-modifying enzyme HISTONE DEACETYLASE 9 (HDA9) mediates thermomorphogenesis but does not interfere with hypocotyl elongation during shade avoidance. HDA9 is stabilized in response to high temperature and mediates histone deacetylation at the YUCCA8 locus, a rate-limiting enzyme in auxin biosynthesis, at warm temperatures. We show that HDA9 permits net eviction of the H2A.Z histone variant from nucleosomes associated with YUCCA8 , allowing binding and transcriptional activation by PHYTOCHROME INTERACTING FACTOR 4, followed by auxin accumulation and thermomorphogenesis.
@article{van_der_woude_histone_2019,
title = {{HISTONE} {DEACETYLASE} 9 stimulates auxin-dependent thermomorphogenesis in \textit{{Arabidopsis} thaliana} by mediating {H2A}.{Z} depletion},
volume = {116},
issn = {0027-8424, 1091-6490},
url = {http://www.pnas.org/lookup/doi/10.1073/pnas.1911694116},
doi = {10.1073/pnas.1911694116},
abstract = {Many plant species respond to unfavorable high ambient temperatures by adjusting their vegetative body plan to facilitate cooling. This process is known as thermomorphogenesis and is induced by the phytohormone auxin. Here, we demonstrate that the chromatin-modifying enzyme HISTONE DEACETYLASE 9 (HDA9) mediates thermomorphogenesis but does not interfere with hypocotyl elongation during shade avoidance. HDA9 is stabilized in response to high temperature and mediates histone deacetylation at the
YUCCA8
locus, a rate-limiting enzyme in auxin biosynthesis, at warm temperatures. We show that HDA9 permits net eviction of the H2A.Z histone variant from nucleosomes associated with
YUCCA8
, allowing binding and transcriptional activation by PHYTOCHROME INTERACTING FACTOR 4, followed by auxin accumulation and thermomorphogenesis.},
language = {en},
number = {50},
urldate = {2021-06-07},
journal = {Proceedings of the National Academy of Sciences},
author = {van der Woude, Lennard C. and Perrella, Giorgio and Snoek, Basten L. and van Hoogdalem, Mark and Novák, Ondřej and van Verk, Marcel C. and van Kooten, Heleen N. and Zorn, Lennert E. and Tonckens, Rolf and Dongus, Joram A. and Praat, Myrthe and Stouten, Evelien A. and Proveniers, Marcel C. G. and Vellutini, Elisa and Patitaki, Eirini and Shapulatov, Umidjon and Kohlen, Wouter and Balasubramanian, Sureshkumar and Ljung, Karin and van der Krol, Alexander R. and Smeekens, Sjef and Kaiserli, Eirini and van Zanten, Martijn},
month = dec,
year = {2019},
pages = {25343--25354},
}
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We show that HDA9 permits net eviction of the H2A.Z histone variant from nucleosomes associated with YUCCA8 , allowing binding and transcriptional activation by PHYTOCHROME INTERACTING FACTOR 4, followed by auxin accumulation and thermomorphogenesis.","language":"en","number":"50","urldate":"2021-06-07","journal":"Proceedings of the National Academy of Sciences","author":[{"propositions":["van","der"],"lastnames":["Woude"],"firstnames":["Lennard","C."],"suffixes":[]},{"propositions":[],"lastnames":["Perrella"],"firstnames":["Giorgio"],"suffixes":[]},{"propositions":[],"lastnames":["Snoek"],"firstnames":["Basten","L."],"suffixes":[]},{"propositions":["van"],"lastnames":["Hoogdalem"],"firstnames":["Mark"],"suffixes":[]},{"propositions":[],"lastnames":["Novák"],"firstnames":["Ondřej"],"suffixes":[]},{"propositions":["van"],"lastnames":["Verk"],"firstnames":["Marcel","C."],"suffixes":[]},{"propositions":["van"],"lastnames":["Kooten"],"firstnames":["Heleen","N."],"suffixes":[]},{"propositions":[],"lastnames":["Zorn"],"firstnames":["Lennert","E."],"suffixes":[]},{"propositions":[],"lastnames":["Tonckens"],"firstnames":["Rolf"],"suffixes":[]},{"propositions":[],"lastnames":["Dongus"],"firstnames":["Joram","A."],"suffixes":[]},{"propositions":[],"lastnames":["Praat"],"firstnames":["Myrthe"],"suffixes":[]},{"propositions":[],"lastnames":["Stouten"],"firstnames":["Evelien","A."],"suffixes":[]},{"propositions":[],"lastnames":["Proveniers"],"firstnames":["Marcel","C.","G."],"suffixes":[]},{"propositions":[],"lastnames":["Vellutini"],"firstnames":["Elisa"],"suffixes":[]},{"propositions":[],"lastnames":["Patitaki"],"firstnames":["Eirini"],"suffixes":[]},{"propositions":[],"lastnames":["Shapulatov"],"firstnames":["Umidjon"],"suffixes":[]},{"propositions":[],"lastnames":["Kohlen"],"firstnames":["Wouter"],"suffixes":[]},{"propositions":[],"lastnames":["Balasubramanian"],"firstnames":["Sureshkumar"],"suffixes":[]},{"propositions":[],"lastnames":["Ljung"],"firstnames":["Karin"],"suffixes":[]},{"propositions":["van","der"],"lastnames":["Krol"],"firstnames":["Alexander","R."],"suffixes":[]},{"propositions":[],"lastnames":["Smeekens"],"firstnames":["Sjef"],"suffixes":[]},{"propositions":[],"lastnames":["Kaiserli"],"firstnames":["Eirini"],"suffixes":[]},{"propositions":["van"],"lastnames":["Zanten"],"firstnames":["Martijn"],"suffixes":[]}],"month":"December","year":"2019","pages":"25343–25354","bibtex":"@article{van_der_woude_histone_2019,\n\ttitle = {{HISTONE} {DEACETYLASE} 9 stimulates auxin-dependent thermomorphogenesis in \\textit{{Arabidopsis} thaliana} by mediating {H2A}.{Z} depletion},\n\tvolume = {116},\n\tissn = {0027-8424, 1091-6490},\n\turl = {http://www.pnas.org/lookup/doi/10.1073/pnas.1911694116},\n\tdoi = {10.1073/pnas.1911694116},\n\tabstract = {Many plant species respond to unfavorable high ambient temperatures by adjusting their vegetative body plan to facilitate cooling. 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We show that HDA9 permits net eviction of the H2A.Z histone variant from nucleosomes associated with\n YUCCA8\n , allowing binding and transcriptional activation by PHYTOCHROME INTERACTING FACTOR 4, followed by auxin accumulation and thermomorphogenesis.},\n\tlanguage = {en},\n\tnumber = {50},\n\turldate = {2021-06-07},\n\tjournal = {Proceedings of the National Academy of Sciences},\n\tauthor = {van der Woude, Lennard C. and Perrella, Giorgio and Snoek, Basten L. and van Hoogdalem, Mark and Novák, Ondřej and van Verk, Marcel C. and van Kooten, Heleen N. and Zorn, Lennert E. and Tonckens, Rolf and Dongus, Joram A. and Praat, Myrthe and Stouten, Evelien A. and Proveniers, Marcel C. 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