@article{van_everdingen_role_1998,
	title = {Role of collateral flow on cerebral hemodynamics in patients with unilateral internal carotid artery occlusion},
	volume = {44},
	issn = {0364-5134},
	url = {http://apps.isiknowledge.com/full_record.do?product=WOS&colname=WOS&search_mode=RelatedRecords&qid=27&SID=Z2Pk@m5OFDhDkp1cpPD&page=1&doc=2},
	abstract = {The objective of this study was to evaluate the role of collateral blood now via the anterior and posterior communicating arteries (ACoA and PCoA) and via the ophthalmic artery (OphA) on cerebral hemodynamics, metabolism, and border zone infarcts in 57 patients with unilateral symptomatic occlusions of the internal carotid artery. Collateral now via the ACoA and PCoA was determined with magnetic resonance angiography (MRA) and collateral flow via the OphA with transcranial Doppler (TCD). Volume flow was studied with MRA, metabolism with H-1 MR spectroscopy, CO2 reactivity with TCD, and the incidence of border zone infarcts with MRI. Compared with controls, patients had deteriorated volume flow metabolism, and CO2 reactivity. No differences were found between patients with and patients without collateral flow through the ACoA and/or PCoA, or between patients with or without collateral flow via the OphA. Patients without collateral flow via any of these collaterals had decreased volume now in the middle cerebral artery, decreased N-acetylaspartate/choline, and increased lactate/N-acetylaspartate, compared with the other patients. Patients with symptomatic internal carotid artery occlusion have deteriorated cerebral hemodynamics and metabolism. Different collateral flow patterns via the ACoA, PCoA, or OphA have no effect on the hemodynamic and metabolic parameters, as long as one of these pathways is present.},
	number = {2},
	urldate = {2008-11-20},
	journal = {ANNALS OF NEUROLOGY},
	author = {van Everdingen, KJ and Visser, GH and Klijn, CJM and Kappelle, LJ and van der Grond, J},
	month = aug,
	year = {1998},
	keywords = {hypercapnia, CO2, CVR, stenosis, TCD, collateral, stroke},
	pages = {167--176},
	file = {ISI Web of Knowledge Snapshot:/Users/nickb/Zotero/storage/3I9HJG7B/full_record.html:text/html;vaneverdingen1998.pdf:/Users/nickb/Zotero/storage/ZPHJG6TR/vaneverdingen1998.pdf:application/pdf}
}

{"_id":"8gG5cYWmbkaSJ9rnY","bibbaseid":"vaneverdingen-visser-klijn-kappelle-vandergrond-roleofcollateralflowoncerebralhemodynamicsinpatientswithunilateralinternalcarotidarteryocclusion-1998","downloads":0,"creationDate":"2017-07-20T09:27:29.485Z","title":"Role of collateral flow on cerebral hemodynamics in patients with unilateral internal carotid artery occlusion","author_short":["van Everdingen, K.","Visser, G.","Klijn, C.","Kappelle, L.","van der Grond, J"],"year":1998,"bibtype":"article","biburl":"https://users.fmrib.ox.ac.uk/~nickb/ExportedItemsLge.bib","bibdata":{"bibtype":"article","type":"article","title":"Role of collateral flow on cerebral hemodynamics in patients with unilateral internal carotid artery occlusion","volume":"44","issn":"0364-5134","url":"http://apps.isiknowledge.com/full_record.do?product=WOS&colname=WOS&search_mode=RelatedRecords&qid=27&SID=Z2Pk@m5OFDhDkp1cpPD&page=1&doc=2","abstract":"The objective of this study was to evaluate the role of collateral blood now via the anterior and posterior communicating arteries (ACoA and PCoA) and via the ophthalmic artery (OphA) on cerebral hemodynamics, metabolism, and border zone infarcts in 57 patients with unilateral symptomatic occlusions of the internal carotid artery. Collateral now via the ACoA and PCoA was determined with magnetic resonance angiography (MRA) and collateral flow via the OphA with transcranial Doppler (TCD). Volume flow was studied with MRA, metabolism with H-1 MR spectroscopy, CO2 reactivity with TCD, and the incidence of border zone infarcts with MRI. Compared with controls, patients had deteriorated volume flow metabolism, and CO2 reactivity. No differences were found between patients with and patients without collateral flow through the ACoA and/or PCoA, or between patients with or without collateral flow via the OphA. Patients without collateral flow via any of these collaterals had decreased volume now in the middle cerebral artery, decreased N-acetylaspartate/choline, and increased lactate/N-acetylaspartate, compared with the other patients. Patients with symptomatic internal carotid artery occlusion have deteriorated cerebral hemodynamics and metabolism. Different collateral flow patterns via the ACoA, PCoA, or OphA have no effect on the hemodynamic and metabolic parameters, as long as one of these pathways is present.","number":"2","urldate":"2008-11-20","journal":"ANNALS OF NEUROLOGY","author":[{"propositions":["van"],"lastnames":["Everdingen"],"firstnames":["KJ"],"suffixes":[]},{"propositions":[],"lastnames":["Visser"],"firstnames":["GH"],"suffixes":[]},{"propositions":[],"lastnames":["Klijn"],"firstnames":["CJM"],"suffixes":[]},{"propositions":[],"lastnames":["Kappelle"],"firstnames":["LJ"],"suffixes":[]},{"propositions":["van","der"],"lastnames":["Grond"],"firstnames":["J"],"suffixes":[]}],"month":"August","year":"1998","keywords":"hypercapnia, CO2, CVR, stenosis, TCD, collateral, stroke","pages":"167--176","file":"ISI Web of Knowledge Snapshot:/Users/nickb/Zotero/storage/3I9HJG7B/full_record.html:text/html;vaneverdingen1998.pdf:/Users/nickb/Zotero/storage/ZPHJG6TR/vaneverdingen1998.pdf:application/pdf","bibtex":"@article{van_everdingen_role_1998,\n\ttitle = {Role of collateral flow on cerebral hemodynamics in patients with unilateral internal carotid artery occlusion},\n\tvolume = {44},\n\tissn = {0364-5134},\n\turl = {http://apps.isiknowledge.com/full_record.do?product=WOS&colname=WOS&search_mode=RelatedRecords&qid=27&SID=Z2Pk@m5OFDhDkp1cpPD&page=1&doc=2},\n\tabstract = {The objective of this study was to evaluate the role of collateral blood now via the anterior and posterior communicating arteries (ACoA and PCoA) and via the ophthalmic artery (OphA) on cerebral hemodynamics, metabolism, and border zone infarcts in 57 patients with unilateral symptomatic occlusions of the internal carotid artery. Collateral now via the ACoA and PCoA was determined with magnetic resonance angiography (MRA) and collateral flow via the OphA with transcranial Doppler (TCD). Volume flow was studied with MRA, metabolism with H-1 MR spectroscopy, CO2 reactivity with TCD, and the incidence of border zone infarcts with MRI. Compared with controls, patients had deteriorated volume flow metabolism, and CO2 reactivity. No differences were found between patients with and patients without collateral flow through the ACoA and/or PCoA, or between patients with or without collateral flow via the OphA. Patients without collateral flow via any of these collaterals had decreased volume now in the middle cerebral artery, decreased N-acetylaspartate/choline, and increased lactate/N-acetylaspartate, compared with the other patients. Patients with symptomatic internal carotid artery occlusion have deteriorated cerebral hemodynamics and metabolism. Different collateral flow patterns via the ACoA, PCoA, or OphA have no effect on the hemodynamic and metabolic parameters, as long as one of these pathways is present.},\n\tnumber = {2},\n\turldate = {2008-11-20},\n\tjournal = {ANNALS OF NEUROLOGY},\n\tauthor = {van Everdingen, KJ and Visser, GH and Klijn, CJM and Kappelle, LJ and van der Grond, J},\n\tmonth = aug,\n\tyear = {1998},\n\tkeywords = {hypercapnia, CO2, CVR, stenosis, TCD, collateral, stroke},\n\tpages = {167--176},\n\tfile = {ISI Web of Knowledge Snapshot:/Users/nickb/Zotero/storage/3I9HJG7B/full_record.html:text/html;vaneverdingen1998.pdf:/Users/nickb/Zotero/storage/ZPHJG6TR/vaneverdingen1998.pdf:application/pdf}\n}\n\n","author_short":["van Everdingen, K.","Visser, G.","Klijn, C.","Kappelle, L.","van der Grond, J"],"key":"van_everdingen_role_1998","id":"van_everdingen_role_1998","bibbaseid":"vaneverdingen-visser-klijn-kappelle-vandergrond-roleofcollateralflowoncerebralhemodynamicsinpatientswithunilateralinternalcarotidarteryocclusion-1998","role":"author","urls":{"Paper":"http://apps.isiknowledge.com/full_record.do?product=WOS&colname=WOS&search_mode=RelatedRecords&qid=27&SID=Z2Pk@m5OFDhDkp1cpPD&page=1&doc=2"},"keyword":["hypercapnia","CO2","CVR","stenosis","TCD","collateral","stroke"],"downloads":0,"html":""},"search_terms":["role","collateral","flow","cerebral","hemodynamics","patients","unilateral","internal","carotid","artery","occlusion","van everdingen","visser","klijn","kappelle","van der grond"],"keywords":["hypercapnia","co2","cvr","stenosis","tcd","collateral","stroke"],"authorIDs":[],"dataSources":["ZnSCiZ543imjXQzRu"]}