{"_id":"JrhKhLBNX7tMi8bax","bibbaseid":"varkaris-fecedelacruz-martin-norden-chevalier-kehlmann-leshchiner-barnes-etal-allostericpi3kalphainhibitionovercomesontargetresistancetoorthostericinhibitorsmediatedbysecondarypik3camutations-2023","author_short":["Varkaris, A.","Fece de la Cruz, F.","Martin, E. E","Norden, B. L","Chevalier, N.","Kehlmann, A. M","Leshchiner, I.","Barnes, H.","Ehnstrom, S.","Stavridi, A.","others"],"bibdata":{"bibtype":"article","type":"article","title":"Allosteric PI3K-alpha inhibition overcomes on-target resistance to orthosteric inhibitors mediated by secondary PIK3CA mutations.","author":[{"propositions":[],"lastnames":["Varkaris"],"firstnames":["Andreas"],"suffixes":[]},{"propositions":["Fece","de","la"],"lastnames":["Cruz"],"firstnames":["Ferran"],"suffixes":[]},{"propositions":[],"lastnames":["Martin"],"firstnames":["Elizabeth","E"],"suffixes":[]},{"propositions":[],"lastnames":["Norden"],"firstnames":["Bryanna","L"],"suffixes":[]},{"propositions":[],"lastnames":["Chevalier"],"firstnames":["Nicholas"],"suffixes":[]},{"propositions":[],"lastnames":["Kehlmann"],"firstnames":["Allison","M"],"suffixes":[]},{"propositions":[],"lastnames":["Leshchiner"],"firstnames":["Ignaty"],"suffixes":[]},{"propositions":[],"lastnames":["Barnes"],"firstnames":["Haley"],"suffixes":[]},{"propositions":[],"lastnames":["Ehnstrom"],"firstnames":["Sara"],"suffixes":[]},{"propositions":[],"lastnames":["Stavridi"],"firstnames":["Anastasia-Maria"],"suffixes":[]},{"firstnames":[],"propositions":[],"lastnames":["others"],"suffixes":[]}],"journal":"Cancer Discovery","year":"2023","publisher":"American Association for Cancer Research","bibtex":"@article{varkaris2023allosteric,\n title={Allosteric PI3K-alpha inhibition overcomes on-target resistance to orthosteric inhibitors mediated by secondary PIK3CA mutations.},\n author={Varkaris, Andreas and Fece de la Cruz, Ferran and Martin, Elizabeth E and Norden, Bryanna L and Chevalier, Nicholas and Kehlmann, Allison M and Leshchiner, Ignaty and Barnes, Haley and Ehnstrom, Sara and Stavridi, Anastasia-Maria and others},\n journal={Cancer Discovery},\n year={2023},\n publisher={American Association for Cancer Research}\n}\n","author_short":["Varkaris, A.","Fece de la Cruz, F.","Martin, E. E","Norden, B. L","Chevalier, N.","Kehlmann, A. M","Leshchiner, I.","Barnes, H.","Ehnstrom, S.","Stavridi, A.","others"],"key":"varkaris2023allosteric","id":"varkaris2023allosteric","bibbaseid":"varkaris-fecedelacruz-martin-norden-chevalier-kehlmann-leshchiner-barnes-etal-allostericpi3kalphainhibitionovercomesontargetresistancetoorthostericinhibitorsmediatedbysecondarypik3camutations-2023","role":"author","urls":{},"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/network/files/aX4e85mNvLnP28bmF","dataSources":["N3rXpkDkdbEvNCA76","hky9vNrwc9uGBMQ9h"],"keywords":[],"search_terms":["allosteric","pi3k","alpha","inhibition","overcomes","target","resistance","orthosteric","inhibitors","mediated","secondary","pik3ca","mutations","varkaris","fece de la cruz","martin","norden","chevalier","kehlmann","leshchiner","barnes","ehnstrom","stavridi","others"],"title":"Allosteric PI3K-alpha inhibition overcomes on-target resistance to orthosteric inhibitors mediated by secondary PIK3CA mutations.","year":2023}