@article{vesala_mitochondrial_2024,
	title = {Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in {Drosophila}},
	volume = {22},
	copyright = {All rights reserved},
	issn = {1741-7007},
	url = {https://doi.org/10.1186/s12915-024-01858-5},
	doi = {10.1186/s12915-024-01858-5},
	abstract = {Mitochondria participate in various cellular processes including energy metabolism, apoptosis, autophagy, production of reactive oxygen species, stress responses, inflammation and immunity. However, the role of mitochondrial metabolism in immune cells and tissues shaping the innate immune responses are not yet fully understood. We investigated the effects of tissue-specific mitochondrial perturbation on the immune responses at the organismal level. Genes for oxidative phosphorylation (OXPHOS) complexes cI-cV were knocked down in the fruit fly Drosophila melanogaster, targeting the two main immune tissues, the fat body and the immune cells (hemocytes).},
	number = {1},
	urldate = {2024-03-13},
	journal = {BMC Biology},
	author = {Vesala, Laura and Basikhina, Yuliya and Tuomela, Tea and Nurminen, Anssi and Siukola, Emilia and Vale, Pedro F. and Salminen, Tiina S.},
	month = mar,
	year = {2024},
	pages = {60},
}

{"_id":"h5KeYghk93xYPRAAd","bibbaseid":"vesala-basikhina-tuomela-nurminen-siukola-vale-salminen-mitochondrialperturbationinimmunecellsenhancescellmediatedinnateimmunityindrosophila-2024","author_short":["Vesala, L.","Basikhina, Y.","Tuomela, T.","Nurminen, A.","Siukola, E.","Vale, P. F.","Salminen, T. S."],"bibdata":{"bibtype":"article","type":"article","title":"Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila","volume":"22","copyright":"All rights reserved","issn":"1741-7007","url":"https://doi.org/10.1186/s12915-024-01858-5","doi":"10.1186/s12915-024-01858-5","abstract":"Mitochondria participate in various cellular processes including energy metabolism, apoptosis, autophagy, production of reactive oxygen species, stress responses, inflammation and immunity. However, the role of mitochondrial metabolism in immune cells and tissues shaping the innate immune responses are not yet fully understood. We investigated the effects of tissue-specific mitochondrial perturbation on the immune responses at the organismal level. Genes for oxidative phosphorylation (OXPHOS) complexes cI-cV were knocked down in the fruit fly Drosophila melanogaster, targeting the two main immune tissues, the fat body and the immune cells (hemocytes).","number":"1","urldate":"2024-03-13","journal":"BMC Biology","author":[{"propositions":[],"lastnames":["Vesala"],"firstnames":["Laura"],"suffixes":[]},{"propositions":[],"lastnames":["Basikhina"],"firstnames":["Yuliya"],"suffixes":[]},{"propositions":[],"lastnames":["Tuomela"],"firstnames":["Tea"],"suffixes":[]},{"propositions":[],"lastnames":["Nurminen"],"firstnames":["Anssi"],"suffixes":[]},{"propositions":[],"lastnames":["Siukola"],"firstnames":["Emilia"],"suffixes":[]},{"propositions":[],"lastnames":["Vale"],"firstnames":["Pedro","F."],"suffixes":[]},{"propositions":[],"lastnames":["Salminen"],"firstnames":["Tiina","S."],"suffixes":[]}],"month":"March","year":"2024","pages":"60","bibtex":"@article{vesala_mitochondrial_2024,\n\ttitle = {Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in {Drosophila}},\n\tvolume = {22},\n\tcopyright = {All rights reserved},\n\tissn = {1741-7007},\n\turl = {https://doi.org/10.1186/s12915-024-01858-5},\n\tdoi = {10.1186/s12915-024-01858-5},\n\tabstract = {Mitochondria participate in various cellular processes including energy metabolism, apoptosis, autophagy, production of reactive oxygen species, stress responses, inflammation and immunity. However, the role of mitochondrial metabolism in immune cells and tissues shaping the innate immune responses are not yet fully understood. We investigated the effects of tissue-specific mitochondrial perturbation on the immune responses at the organismal level. Genes for oxidative phosphorylation (OXPHOS) complexes cI-cV were knocked down in the fruit fly Drosophila melanogaster, targeting the two main immune tissues, the fat body and the immune cells (hemocytes).},\n\tnumber = {1},\n\turldate = {2024-03-13},\n\tjournal = {BMC Biology},\n\tauthor = {Vesala, Laura and Basikhina, Yuliya and Tuomela, Tea and Nurminen, Anssi and Siukola, Emilia and Vale, Pedro F. and Salminen, Tiina S.},\n\tmonth = mar,\n\tyear = {2024},\n\tpages = {60},\n}\n\n\n\n","author_short":["Vesala, L.","Basikhina, Y.","Tuomela, T.","Nurminen, A.","Siukola, E.","Vale, P. F.","Salminen, T. S."],"key":"vesala_mitochondrial_2024","id":"vesala_mitochondrial_2024","bibbaseid":"vesala-basikhina-tuomela-nurminen-siukola-vale-salminen-mitochondrialperturbationinimmunecellsenhancescellmediatedinnateimmunityindrosophila-2024","role":"author","urls":{"Paper":"https://doi.org/10.1186/s12915-024-01858-5"},"metadata":{"authorlinks":{}},"downloads":4},"bibtype":"article","biburl":"https://bibbase.org/zotero-mypublications/pfvale","dataSources":["Hmaj6fS6FKQuG3nSG","66wkvtmTF9APhQn6L","tWbkRzQp4qoRJ9g7W","WhdFcL9q2Loo6bDrg","rf5D6MWTahxXEXZ5P"],"keywords":[],"search_terms":["mitochondrial","perturbation","immune","cells","enhances","cell","mediated","innate","immunity","drosophila","vesala","basikhina","tuomela","nurminen","siukola","vale","salminen"],"title":"Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila","year":2024,"downloads":4}