Electrophysiological correlations of morphological restructuring in experimental local ischemia of different severity in the rat sensorimotor cortex. Volkova, D. A., Kositzyn, N. S., Goloborodko, E. V., Loginova, N. A., & Svinov, M. M. Bulletin of Experimental Biology and Medicine, 155(2):264--267, June, 2013. 00000 abstract bibtex Local cerebrovascular disorders were modeled by reversible photochemical clotting of hemispheric cortical vessels. Mild ischemia led to reversible edema in the surface layers of the cortex: cytotoxic edema of the neuropile, primarily of the distal dendrites. This status led to an increase in the lower delta rhythm frequency band power. After administration of systemic anesthetic, delta rhythm appeared sooner in the ischemic foci than in intact cortical areas. More severe ischemia led to the appearance of dark and pyknotic neurons and reduction of oscillation power in all EEG spectrum bands. Restructuring of primarily dendrites caused by local moderate ischemia of the surface cortical layers at the early stage of neurodegenerative processes stimulated the inhibitory recovery processes.
@article{volkova_electrophysiological_2013,
title = {Electrophysiological correlations of morphological restructuring in experimental local ischemia of different severity in the rat sensorimotor cortex},
volume = {155},
issn = {1573-8221},
abstract = {Local cerebrovascular disorders were modeled by reversible photochemical clotting of hemispheric cortical vessels. Mild ischemia led to reversible edema in the surface layers of the cortex: cytotoxic edema of the neuropile, primarily of the distal dendrites. This status led to an increase in the lower delta rhythm frequency band power. After administration of systemic anesthetic, delta rhythm appeared sooner in the ischemic foci than in intact cortical areas. More severe ischemia led to the appearance of dark and pyknotic neurons and reduction of oscillation power in all EEG spectrum bands. Restructuring of primarily dendrites caused by local moderate ischemia of the surface cortical layers at the early stage of neurodegenerative processes stimulated the inhibitory recovery processes.},
language = {eng},
number = {2},
journal = {Bulletin of Experimental Biology and Medicine},
author = {Volkova, D. A. and Kositzyn, N. S. and Goloborodko, E. V. and Loginova, N. A. and Svinov, M. M.},
month = jun,
year = {2013},
pmid = {24131005},
note = {00000 },
keywords = {Anesthetics, Animals, Brain, Cerebral Cortex, Cerebral Infarction, Delta Rhythm, Dendrites, Electroencephalography, Hypoxia-Ischemia, Brain, Male, Neuropil, Rats, Rats, Wistar, Rose Bengal},
pages = {264--267}
}
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