Enhanced susceptibility for acquired torsade de pointes arrhythmias in the dog with chronic, complete AV block is related to cardiac hypertrophy and electrical remodeling. Vos, M., Grootde, Verduyn, S., dervan, Leunissen, H., Cleutjens, J., Bilsenvan, Daemen, M., Schreuder, J., Allessie, M., & Wellens, H. j-C, 98(11):1125--35, 1998.
bibtex   
@Article{RSM:Vos98,
  author =       "M.A. Vos and Grootde and S.C. Verduyn and dervan and
                 H.D. Leunissen and J.P. Cleutjens and Bilsenvan and
                 M.J. Daemen and J.J. Schreuder and M.A. Allessie and
                 H.J. Wellens",
  title =        "Enhanced susceptibility for acquired torsade de
                 pointes arrhythmias in the dog with chronic, complete
                 {AV} block is related to cardiac hypertrophy and
                 electrical remodeling.",
  journal =      j-C,
  year =         "1998",
  volume =       "98",
  number =       "11",
  pages =        "1125--35",
  robnote =      "Chronic, complete AV block (CAVB) in the dog leads to
                 ventricular hypertrophy, which has been described as an
                 independent risk factor for arrhythmias.In this model,
                 we examined (1) whether the short- and long-term
                 electrical adaptations predispose to acquired torsade
                 de pointes arrhythmias (TdP) and (2) the nature of the
                 structural and functional adaptations involved.They
                 used d-sotalol to induce TdP with programmed electrical
                 stimulation and found only after the CAVB that they got
                 TdP. LQTS. NO hard copy",
}

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