@Article{RSM:Wei95,
  author =       "D. Wei and O. Okazaki and K. Harumi and E. Harasawa
                 and H. Hosaka",
  title =        "Comparative simulation of excitation and body surface
                 electrocardiogram with isotropic and anisotropic
                 computer heart models.",
  journal =      j-BME,
  year =         "1995",
  month =        apr,
  volume =       "42",
  number =       "4",
  pages =        "343--357",
  robnote =      "Comparative simulations between isotropic and
                 anisotropic computer heart models were conducted to
                 study the effects of myocardial anisotropy on the
                 excitation process of the heart and on body surface
                 electrocardiogram. The isotropic heart model includes
                 atria, ventricles, and a special conduction system, and
                 is electrophysiologically specified by parameters
                 relative to action potential, conduction velocity,
                 automaticity, and pacing. The anisotropic heart model
                 was created by incorporating rotating fiber directions
                 into the ventricles of the isotropic heart model. The
                 orientation of the myocardial fibers in the ventricles
                 of the model was gradually rotated counterclockwise
                 from the epicardial layer to the endocardial layer for
                 a total rotation of 90 degrees. The anisotropy of
                 conduction velocity and intracellular electric
                 conductivity was included in the simulation.
                 Comparative simulations of the normal heart, LBBB, and
                 RBBB showed no significant differences between the two
                 models in the excitation processes of the whole heart
                 or in the body surface electrocardiograms. However, it
                 was easier to induce ventricular fibrillation in the
                 anisotropic model than in the isotropic model. The
                 comparative simulation is useful for investigating the
                 effects of myocardial anisotropy at the whole heart
                 level and for evaluating limitations of the isotropic
                 heart model.",
  bibdate =      "Mon Jan 8 18:24:04 2007",
}

{"_id":"9wHwyWRqAQkec64jJ","bibbaseid":"wei-okazaki-harumi-harasawa-hosaka-comparativesimulationofexcitationandbodysurfaceelectrocardiogramwithisotropicandanisotropiccomputerheartmodels-1995","downloads":0,"creationDate":"2016-07-01T21:38:42.852Z","title":"Comparative simulation of excitation and body surface electrocardiogram with isotropic and anisotropic computer heart models.","author_short":["Wei, D.","Okazaki, O.","Harumi, K.","Harasawa, E.","Hosaka, H."],"year":1995,"bibtype":"article","biburl":"http://www.sci.utah.edu/~macleod/Bibtex/biglit.bib","bibdata":{"bibtype":"article","type":"article","author":[{"firstnames":["D."],"propositions":[],"lastnames":["Wei"],"suffixes":[]},{"firstnames":["O."],"propositions":[],"lastnames":["Okazaki"],"suffixes":[]},{"firstnames":["K."],"propositions":[],"lastnames":["Harumi"],"suffixes":[]},{"firstnames":["E."],"propositions":[],"lastnames":["Harasawa"],"suffixes":[]},{"firstnames":["H."],"propositions":[],"lastnames":["Hosaka"],"suffixes":[]}],"title":"Comparative simulation of excitation and body surface electrocardiogram with isotropic and anisotropic computer heart models.","journal":"j-BME","year":"1995","month":"April","volume":"42","number":"4","pages":"343--357","robnote":"Comparative simulations between isotropic and anisotropic computer heart models were conducted to study the effects of myocardial anisotropy on the excitation process of the heart and on body surface electrocardiogram. The isotropic heart model includes atria, ventricles, and a special conduction system, and is electrophysiologically specified by parameters relative to action potential, conduction velocity, automaticity, and pacing. The anisotropic heart model was created by incorporating rotating fiber directions into the ventricles of the isotropic heart model. The orientation of the myocardial fibers in the ventricles of the model was gradually rotated counterclockwise from the epicardial layer to the endocardial layer for a total rotation of 90 degrees. The anisotropy of conduction velocity and intracellular electric conductivity was included in the simulation. Comparative simulations of the normal heart, LBBB, and RBBB showed no significant differences between the two models in the excitation processes of the whole heart or in the body surface electrocardiograms. However, it was easier to induce ventricular fibrillation in the anisotropic model than in the isotropic model. The comparative simulation is useful for investigating the effects of myocardial anisotropy at the whole heart level and for evaluating limitations of the isotropic heart model.","bibdate":"Mon Jan 8 18:24:04 2007","bibtex":"@Article{RSM:Wei95,\n author = \"D. Wei and O. Okazaki and K. Harumi and E. Harasawa\n and H. Hosaka\",\n title = \"Comparative simulation of excitation and body surface\n electrocardiogram with isotropic and anisotropic\n computer heart models.\",\n journal = j-BME,\n year = \"1995\",\n month = apr,\n volume = \"42\",\n number = \"4\",\n pages = \"343--357\",\n robnote = \"Comparative simulations between isotropic and\n anisotropic computer heart models were conducted to\n study the effects of myocardial anisotropy on the\n excitation process of the heart and on body surface\n electrocardiogram. The isotropic heart model includes\n atria, ventricles, and a special conduction system, and\n is electrophysiologically specified by parameters\n relative to action potential, conduction velocity,\n automaticity, and pacing. The anisotropic heart model\n was created by incorporating rotating fiber directions\n into the ventricles of the isotropic heart model. The\n orientation of the myocardial fibers in the ventricles\n of the model was gradually rotated counterclockwise\n from the epicardial layer to the endocardial layer for\n a total rotation of 90 degrees. The anisotropy of\n conduction velocity and intracellular electric\n conductivity was included in the simulation.\n Comparative simulations of the normal heart, LBBB, and\n RBBB showed no significant differences between the two\n models in the excitation processes of the whole heart\n or in the body surface electrocardiograms. However, it\n was easier to induce ventricular fibrillation in the\n anisotropic model than in the isotropic model. The\n comparative simulation is useful for investigating the\n effects of myocardial anisotropy at the whole heart\n level and for evaluating limitations of the isotropic\n heart model.\",\n bibdate = \"Mon Jan 8 18:24:04 2007\",\n}\n\n","author_short":["Wei, D.","Okazaki, O.","Harumi, K.","Harasawa, E.","Hosaka, H."],"key":"RSM:Wei95","id":"RSM:Wei95","bibbaseid":"wei-okazaki-harumi-harasawa-hosaka-comparativesimulationofexcitationandbodysurfaceelectrocardiogramwithisotropicandanisotropiccomputerheartmodels-1995","role":"author","urls":{},"downloads":0,"html":""},"search_terms":["comparative","simulation","excitation","body","surface","electrocardiogram","isotropic","anisotropic","computer","heart","models","wei","okazaki","harumi","harasawa","hosaka"],"keywords":[],"authorIDs":[],"dataSources":["5HG3Kp8zRwDd7FotB"]}