Hymenolepis nana in mice: a potential model for the study of intestinal immunity (Abstract). Weinmann, C. J. In volume II, pages 589, August, 1974. Facta Publication, Vienna, Austria. B11 (14)
abstract   bibtex   
Abstract: A strong, dose-independent, long-lasting immunity to reinfection with eggs of the dwarf tapeworm Hymenolepis nana was consistently elicited in mice vaccinated orally with only a few, perhaps single, oncospheres attenuated through gamma irradiation. Such immunization required invasion of the intestinal wall by the eliciting parasites but little or no subsequent growth or development beyond the earliest stages was needed to render B alb C mice refractory to challenges with eggs for a year or normal oncospheres yielded levels of immunity that were substantially lower and less persistent in spite of the greater growth, differentiation, and longevity of the immunizing parasites. Observations illustrating these features are presented and their significance discussed from a general viewpoint of intestinal immunity.
@inproceedings{weinmann_hymenolepis_1974,
	title = {Hymenolepis nana in mice: a potential model for the study of intestinal immunity ({Abstract})},
	volume = {II},
	shorttitle = {Hymenolepis nana in mice: a potential model for the study of intestinal immunity ({Abstract})},
	abstract = {Abstract:  A strong, dose-independent, long-lasting immunity to reinfection with eggs of the dwarf tapeworm Hymenolepis nana was consistently elicited in mice vaccinated orally with only a few, perhaps single, oncospheres attenuated through gamma irradiation.  Such immunization required invasion of the intestinal wall by the eliciting parasites but little or no subsequent growth or development beyond the earliest stages was needed to render B alb C mice refractory to challenges with eggs for a year or normal oncospheres yielded levels of immunity that were substantially lower and less persistent in spite of the greater growth, differentiation, and longevity of the immunizing parasites.  Observations illustrating these features are presented and their significance discussed from a general viewpoint of intestinal immunity.},
	publisher = {Facta Publication, Vienna, Austria},
	author = {Weinmann, Clarence J.},
	month = aug,
	year = {1974},
	note = {B11 (14)},
	keywords = {1974, Hymenolepis nana, Weinmann, C. J., immunity, intestinal parasite, parasites, mouse, tapeworm, dwarf, vaccine, tapeworm},
	pages = {589}
}

Downloads: 0