@article{wen_are_2022,
	title = {Are {Mind}-{Body} {Exercise} {Beneficial} for {Treating} {Pain}, {Function}, and {Quality} of {Life} in {Middle}-{Aged} and {Old} {People} {With} {Chronic} {Pain}? {A} {Systematic} {Review} and {Meta}-{Analysis}},
	volume = {14},
	issn = {1663-4365},
	shorttitle = {Are {Mind}-{Body} {Exercise} {Beneficial} for {Treating} {Pain}, {Function}, and {Quality} of {Life} in {Middle}-{Aged} and {Old} {People} {With} {Chronic} {Pain}?},
	url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255956/},
	doi = {10.3389/fnagi.2022.921069},
	abstract = {Background
Aging is a significant risk factor in chronic pain development with extensive disability and greater health care costs. Mind-body exercise (MBE) has been scientifically proven to affect the pain intensity and physical health.

Objectives
To assess the effects of MBE modes (Tai Chi, yoga, and qigong) for treating chronic pain among middle-aged and old people, compared with nonactive and active treatment, as well as function, quality of life, and adverse events.

Methods
We searched PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, and Chinese Scientific Journals Full-Text Database (VIP) till March 2022. No restrictions were chartered within the year and language of publication. We included randomized controlled trials of MBE treatment in middle-aged and elderly people with chronic pain. The overall certainty of evidence was evaluated by using the GRADE approach.

Results
A total of 17 studies (n = 1,332) were included in this review. There was low-certainty evidence indicating that MBE had a moderate effect on reducing pain compared with the nonactive and active control group (standard mean difference (SMD): −0.64, 95\% confidence interval (CI): −0.86 to −0.42, P {\textless} 0.001). Very-low-certainty evidence showed that the pooled SMD for the functional improvement was −0.75 (95\% CI: −1.13 to −0.37, P {\textless} 0.001). Low-certainty evidence presented that no influence was observed in physical component summary (SMD: 0.23, 95\% CI: −0.16 to 0.62, P = 0.24) and mental component summary (SMD: −0.01, 95\% CI −0.39 to 0.36, P = 0.95).

Conclusion
Our results indicated that MBE was an effective treatment for reducing symptoms of middle-aged and elderly people with chronic pain compared with nonactive and active control groups. TC and qigong had obvious benefits for knee osteoarthritis in self-reported function, but the efficacy of chronic low back pain was uncertain. No significant benefit of MBE on quality of life in older adults with chronic pain was found. More high-quality RCTs should be conducted to explore the efficacy and mechanism of MBE on chronic pain in middle-aged and elderly people from various dimensions, such as affective and cognitive dimensions.

Systematic Review Registration
https://www.crd.york.ac.uk/PROSPERO/display\_record.php?RecordID=316591, identifier CRD42022316591.},
	urldate = {2022-07-12},
	journal = {Frontiers in Aging Neuroscience},
	author = {Wen, Yu-Rong and Shi, Jian and Wang, Ya-Fei and Lin, Yang-Yang and Hu, Zheng-Yu and Lin, You-Tian and Wang, Xue-Qiang and Wang, Yu-Ling},
	month = jun,
	year = {2022},
	pmid = {35800981},
	pmcid = {PMC9255956},
	keywords = {Chronic Pain, Exercise, Lifestyle Changes, Mind-Body Exercises},
	pages = {921069},
}

{"_id":"myKqN5ybkSLRp6yJX","bibbaseid":"wen-shi-wang-lin-hu-lin-wang-wang-aremindbodyexercisebeneficialfortreatingpainfunctionandqualityoflifeinmiddleagedandoldpeoplewithchronicpainasystematicreviewandmetaanalysis-2022","author_short":["Wen, Y.","Shi, J.","Wang, Y.","Lin, Y.","Hu, Z.","Lin, Y.","Wang, X.","Wang, Y."],"bibdata":{"bibtype":"article","type":"article","title":"Are Mind-Body Exercise Beneficial for Treating Pain, Function, and Quality of Life in Middle-Aged and Old People With Chronic Pain? A Systematic Review and Meta-Analysis","volume":"14","issn":"1663-4365","shorttitle":"Are Mind-Body Exercise Beneficial for Treating Pain, Function, and Quality of Life in Middle-Aged and Old People With Chronic Pain?","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255956/","doi":"10.3389/fnagi.2022.921069","abstract":"Background Aging is a significant risk factor in chronic pain development with extensive disability and greater health care costs. Mind-body exercise (MBE) has been scientifically proven to affect the pain intensity and physical health. Objectives To assess the effects of MBE modes (Tai Chi, yoga, and qigong) for treating chronic pain among middle-aged and old people, compared with nonactive and active treatment, as well as function, quality of life, and adverse events. Methods We searched PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, and Chinese Scientific Journals Full-Text Database (VIP) till March 2022. No restrictions were chartered within the year and language of publication. We included randomized controlled trials of MBE treatment in middle-aged and elderly people with chronic pain. The overall certainty of evidence was evaluated by using the GRADE approach. Results A total of 17 studies (n = 1,332) were included in this review. There was low-certainty evidence indicating that MBE had a moderate effect on reducing pain compared with the nonactive and active control group (standard mean difference (SMD): −0.64, 95% confidence interval (CI): −0.86 to −0.42, P \\textless 0.001). Very-low-certainty evidence showed that the pooled SMD for the functional improvement was −0.75 (95% CI: −1.13 to −0.37, P \\textless 0.001). Low-certainty evidence presented that no influence was observed in physical component summary (SMD: 0.23, 95% CI: −0.16 to 0.62, P = 0.24) and mental component summary (SMD: −0.01, 95% CI −0.39 to 0.36, P = 0.95). Conclusion Our results indicated that MBE was an effective treatment for reducing symptoms of middle-aged and elderly people with chronic pain compared with nonactive and active control groups. TC and qigong had obvious benefits for knee osteoarthritis in self-reported function, but the efficacy of chronic low back pain was uncertain. No significant benefit of MBE on quality of life in older adults with chronic pain was found. More high-quality RCTs should be conducted to explore the efficacy and mechanism of MBE on chronic pain in middle-aged and elderly people from various dimensions, such as affective and cognitive dimensions. Systematic Review Registration https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=316591, identifier CRD42022316591.","urldate":"2022-07-12","journal":"Frontiers in Aging Neuroscience","author":[{"propositions":[],"lastnames":["Wen"],"firstnames":["Yu-Rong"],"suffixes":[]},{"propositions":[],"lastnames":["Shi"],"firstnames":["Jian"],"suffixes":[]},{"propositions":[],"lastnames":["Wang"],"firstnames":["Ya-Fei"],"suffixes":[]},{"propositions":[],"lastnames":["Lin"],"firstnames":["Yang-Yang"],"suffixes":[]},{"propositions":[],"lastnames":["Hu"],"firstnames":["Zheng-Yu"],"suffixes":[]},{"propositions":[],"lastnames":["Lin"],"firstnames":["You-Tian"],"suffixes":[]},{"propositions":[],"lastnames":["Wang"],"firstnames":["Xue-Qiang"],"suffixes":[]},{"propositions":[],"lastnames":["Wang"],"firstnames":["Yu-Ling"],"suffixes":[]}],"month":"June","year":"2022","pmid":"35800981","pmcid":"PMC9255956","keywords":"Chronic Pain, Exercise, Lifestyle Changes, Mind-Body Exercises","pages":"921069","bibtex":"@article{wen_are_2022,\n\ttitle = {Are {Mind}-{Body} {Exercise} {Beneficial} for {Treating} {Pain}, {Function}, and {Quality} of {Life} in {Middle}-{Aged} and {Old} {People} {With} {Chronic} {Pain}? {A} {Systematic} {Review} and {Meta}-{Analysis}},\n\tvolume = {14},\n\tissn = {1663-4365},\n\tshorttitle = {Are {Mind}-{Body} {Exercise} {Beneficial} for {Treating} {Pain}, {Function}, and {Quality} of {Life} in {Middle}-{Aged} and {Old} {People} {With} {Chronic} {Pain}?},\n\turl = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255956/},\n\tdoi = {10.3389/fnagi.2022.921069},\n\tabstract = {Background\nAging is a significant risk factor in chronic pain development with extensive disability and greater health care costs. Mind-body exercise (MBE) has been scientifically proven to affect the pain intensity and physical health.\n\nObjectives\nTo assess the effects of MBE modes (Tai Chi, yoga, and qigong) for treating chronic pain among middle-aged and old people, compared with nonactive and active treatment, as well as function, quality of life, and adverse events.\n\nMethods\nWe searched PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, and Chinese Scientific Journals Full-Text Database (VIP) till March 2022. No restrictions were chartered within the year and language of publication. We included randomized controlled trials of MBE treatment in middle-aged and elderly people with chronic pain. The overall certainty of evidence was evaluated by using the GRADE approach.\n\nResults\nA total of 17 studies (n = 1,332) were included in this review. There was low-certainty evidence indicating that MBE had a moderate effect on reducing pain compared with the nonactive and active control group (standard mean difference (SMD): −0.64, 95\\% confidence interval (CI): −0.86 to −0.42, P {\\textless} 0.001). Very-low-certainty evidence showed that the pooled SMD for the functional improvement was −0.75 (95\\% CI: −1.13 to −0.37, P {\\textless} 0.001). Low-certainty evidence presented that no influence was observed in physical component summary (SMD: 0.23, 95\\% CI: −0.16 to 0.62, P = 0.24) and mental component summary (SMD: −0.01, 95\\% CI −0.39 to 0.36, P = 0.95).\n\nConclusion\nOur results indicated that MBE was an effective treatment for reducing symptoms of middle-aged and elderly people with chronic pain compared with nonactive and active control groups. TC and qigong had obvious benefits for knee osteoarthritis in self-reported function, but the efficacy of chronic low back pain was uncertain. No significant benefit of MBE on quality of life in older adults with chronic pain was found. More high-quality RCTs should be conducted to explore the efficacy and mechanism of MBE on chronic pain in middle-aged and elderly people from various dimensions, such as affective and cognitive dimensions.\n\nSystematic Review Registration\nhttps://www.crd.york.ac.uk/PROSPERO/display\\_record.php?RecordID=316591, identifier CRD42022316591.},\n\turldate = {2022-07-12},\n\tjournal = {Frontiers in Aging Neuroscience},\n\tauthor = {Wen, Yu-Rong and Shi, Jian and Wang, Ya-Fei and Lin, Yang-Yang and Hu, Zheng-Yu and Lin, You-Tian and Wang, Xue-Qiang and Wang, Yu-Ling},\n\tmonth = jun,\n\tyear = {2022},\n\tpmid = {35800981},\n\tpmcid = {PMC9255956},\n\tkeywords = {Chronic Pain, Exercise, Lifestyle Changes, Mind-Body Exercises},\n\tpages = {921069},\n}\n","author_short":["Wen, Y.","Shi, J.","Wang, Y.","Lin, Y.","Hu, Z.","Lin, Y.","Wang, X.","Wang, Y."],"key":"wen_are_2022","id":"wen_are_2022","bibbaseid":"wen-shi-wang-lin-hu-lin-wang-wang-aremindbodyexercisebeneficialfortreatingpainfunctionandqualityoflifeinmiddleagedandoldpeoplewithchronicpainasystematicreviewandmetaanalysis-2022","role":"author","urls":{"Click Here To View Paper":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9255956/"},"keyword":["Chronic Pain","Exercise","Lifestyle Changes","Mind-Body Exercises"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://api.zotero.org/groups/4733365/items?key=itzZVvgBKSuDGGUFLbpmYATc&format=bibtex&limit=100","dataSources":["6Gqmry5ffEs4WQCGg","SWAPFxZkSK8WMMAip","o98C7uRsmjByqkPCA","gCFnrwskxBmgEefxy","pjimXMxN4rzvtt9sP","XairzSTRGcWmZucEz","iHXWag2ky8iGN7FD6","HFC4s32jy77bR6BDE"],"keywords":["chronic pain","exercise","lifestyle changes","mind-body exercises"],"search_terms":["mind","body","exercise","beneficial","treating","pain","function","quality","life","middle","aged","old","people","chronic","pain","systematic","review","meta","analysis","wen","shi","wang","lin","hu","lin","wang","wang"],"title":"Are Mind-Body Exercise Beneficial for Treating Pain, Function, and Quality of Life in Middle-Aged and Old People With Chronic Pain? A Systematic Review and Meta-Analysis","year":2022}