The biosynthetic potential of myxobacteria and their impact in drug discovery. Wenzel, S. C. & Müller, R. Curr Opin Drug Discov Devel, 12(2):220–230, 2009. abstract bibtex Myxobacteria produce an immense variety of natural products with useful biological activities. This review highlights recent advances to evaluate and further explore their biosynthetic potential for drug discovery, with particular focus on polyketide synthase and non-ribosomal peptide synthetase-derived secondary metabolites.
@Article{wenzel09biosynthetic,
author = {Wenzel, Silke C. and M\"uller, Rolf},
title = {The biosynthetic potential of myxobacteria and their impact in drug discovery.},
journal = {Curr Opin Drug Discov Devel},
year = {2009},
volume = {12},
number = {2},
pages = {220--230},
abstract = {Myxobacteria produce an immense variety of natural products with useful biological activities. This review highlights recent advances to evaluate and further explore their biosynthetic potential for drug discovery, with particular focus on polyketide synthase and non-ribosomal peptide synthetase-derived secondary metabolites.},
keywords = {Animals; Anti-Infective Agents; Antineoplastic Agents; Biological Agents, biosynthesis/chemistry/genetics/pharmacology; Drug Discovery; Gene Expression Regulation; Gene Regulatory Networks; Humans; Myxococcales, enzymology/genetics; Peptide Synthases; Polyketide Synthases; Structure-Activity Relationship},
optmonth = mar,
owner = {marmeu},
pmid = {19333867},
timestamp = {2012.12.14},
}
Downloads: 0
{"_id":"dvMkTnLy8LL69Zsy4","bibbaseid":"wenzel-mller-thebiosyntheticpotentialofmyxobacteriaandtheirimpactindrugdiscovery-2009","authorIDs":[],"author_short":["Wenzel, S. C.","Müller, R."],"bibdata":{"bibtype":"article","type":"article","author":[{"propositions":[],"lastnames":["Wenzel"],"firstnames":["Silke","C."],"suffixes":[]},{"propositions":[],"lastnames":["Müller"],"firstnames":["Rolf"],"suffixes":[]}],"title":"The biosynthetic potential of myxobacteria and their impact in drug discovery.","journal":"Curr Opin Drug Discov Devel","year":"2009","volume":"12","number":"2","pages":"220–230","abstract":"Myxobacteria produce an immense variety of natural products with useful biological activities. This review highlights recent advances to evaluate and further explore their biosynthetic potential for drug discovery, with particular focus on polyketide synthase and non-ribosomal peptide synthetase-derived secondary metabolites.","keywords":"Animals; Anti-Infective Agents; Antineoplastic Agents; Biological Agents, biosynthesis/chemistry/genetics/pharmacology; Drug Discovery; Gene Expression Regulation; Gene Regulatory Networks; Humans; Myxococcales, enzymology/genetics; Peptide Synthases; Polyketide Synthases; Structure-Activity Relationship","optmonth":"March","owner":"marmeu","pmid":"19333867","timestamp":"2012.12.14","bibtex":"@Article{wenzel09biosynthetic,\n author = {Wenzel, Silke C. and M\\\"uller, Rolf},\n title = {The biosynthetic potential of myxobacteria and their impact in drug discovery.},\n journal = {Curr Opin Drug Discov Devel},\n year = {2009},\n volume = {12},\n number = {2},\n pages = {220--230},\n abstract = {Myxobacteria produce an immense variety of natural products with useful biological activities. This review highlights recent advances to evaluate and further explore their biosynthetic potential for drug discovery, with particular focus on polyketide synthase and non-ribosomal peptide synthetase-derived secondary metabolites.},\n keywords = {Animals; Anti-Infective Agents; Antineoplastic Agents; Biological Agents, biosynthesis/chemistry/genetics/pharmacology; Drug Discovery; Gene Expression Regulation; Gene Regulatory Networks; Humans; Myxococcales, enzymology/genetics; Peptide Synthases; Polyketide Synthases; Structure-Activity Relationship},\n optmonth = mar,\n owner = {marmeu},\n pmid = {19333867},\n timestamp = {2012.12.14},\n}\n\n","author_short":["Wenzel, S. C.","Müller, R."],"key":"wenzel09biosynthetic","id":"wenzel09biosynthetic","bibbaseid":"wenzel-mller-thebiosyntheticpotentialofmyxobacteriaandtheirimpactindrugdiscovery-2009","role":"author","urls":{},"keyword":["Animals; Anti-Infective Agents; Antineoplastic Agents; Biological Agents","biosynthesis/chemistry/genetics/pharmacology; Drug Discovery; Gene Expression Regulation; Gene Regulatory Networks; Humans; Myxococcales","enzymology/genetics; Peptide Synthases; Polyketide Synthases; Structure-Activity Relationship"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://git.bio.informatik.uni-jena.de/fleisch/literature/raw/master/group-literature.bib","creationDate":"2019-11-19T16:50:42.820Z","downloads":0,"keywords":["animals; anti-infective agents; antineoplastic agents; biological agents","biosynthesis/chemistry/genetics/pharmacology; drug discovery; gene expression regulation; gene regulatory networks; humans; myxococcales","enzymology/genetics; peptide synthases; polyketide synthases; structure-activity relationship"],"search_terms":["biosynthetic","potential","myxobacteria","impact","drug","discovery","wenzel","müller"],"title":"The biosynthetic potential of myxobacteria and their impact in drug discovery.","year":2009,"dataSources":["C5FtkvWWggFfMJTFX"]}