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@article{wood_high_2008,
	title = {High heritability for a composite index of children's activity level measures.},
	volume = {38},
	issn = {0001-8244},
	url = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2493057&tool=pmcentrez&rendertype=abstract},
	doi = {10.1007/s10519-008-9196-1},
	abstract = {Despite the high heritability of children's activity level, which forms part of the core symptom domain of hyperactivity-impulsivity within attention deficit hyperactivity disorder (ADHD), there has only been a limited success with identifying candidate genes involved in its etiology. This may reflect a lack of understanding about the different measures used to define activity level across studies. We aimed to study the genetic and environmental etiology across three measures of activity level: parent and teacher ratings of hyperactivity-impulsivity and actigraph measurements, within a population-based sample of 463 7-9 year old twin pairs. We further examined ways in which the three measures could be combined for future molecular studies. Phenotypic correlations across measures were modest, but a common underlying phenotypic factor was highly heritable (92\%); as was a simple aggregation of all three measurements (77\%). This suggests that distilling what is common to all three measures may be a good method for generating a quantitative trait suitable for molecular studies of activity level in children. The high heritabilities found are encouraging in this respect.},
	number = {3},
	urldate = {2015-05-12},
	journal = {Behavior genetics},
	author = {Wood, Alexis C and Rijsdijk, Frühling and Saudino, Kimberly J and Asherson, Philip and Kuntsi, Jonna},
	month = may,
	year = {2008},
	pmid = {18297388},
	keywords = {Attention Deficit and Disruptive Behavior Disorder, Child, Family Health, Female, Genetic Predisposition to Disease, Humans, Impulsive Behavior, Impulsive Behavior: genetics, Male, Models, Genetic, Models, Statistical, Motor Activity, Multivariate Analysis, Parents, Phenotype},
	pages = {266--76},
}