Deep brain stimulation induces sparse distributions of locally modulated neuronal activity. Xiao, Y., Agnesi, F, Bello, E., Zhang, S, Vitek, J., & ... Scientific reports, nature.com, 2018. Paper abstract bibtex Deep brain stimulation (DBS) therapy is a potent tool for treating a range of brain disorders. High frequency stimulation (HFS) patterns used in DBS therapy are known to modulate neuronal spike rates and patterns in the stimulated nucleus; however, the spatial distribution of these modulated responses are not well understood. Computational models suggest that HFS modulates a volume of tissue spatially concentrated around the active electrode. Here, we tested this theory by investigating modulation of spike rates and patterns in non-human …
@article{pop00096,
author = {YZ Xiao and F Agnesi and EM Bello and S Zhang and JL Vitek and ...},
type = {HTML},
title = {Deep brain stimulation induces sparse distributions of locally modulated neuronal activity},
journal = {Scientific reports},
publisher = {nature.com},
url = {https://www.nature.com/articles/s41598-018-20428-8},
fulltext = {https://www.nature.com/articles/s41598-018-20428-8},
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year = {2018},
abstract = {Deep brain stimulation (DBS) therapy is a potent tool for treating a range of brain disorders. High frequency stimulation (HFS) patterns used in DBS therapy are known to modulate neuronal spike rates and patterns in the stimulated nucleus; however, the spatial distribution of these modulated responses are not well understood. Computational models suggest that HFS modulates a volume of tissue spatially concentrated around the active electrode. Here, we tested this theory by investigating modulation of spike rates and patterns in non-human …},
}
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