The effects of microdose LSD on time perception: a randomised, double-blind, placebo-controlled trial. Yanakieva, S., Polychroni, N., Family, N., Williams, L. T. J., Luke, D. P., & Terhune, D. B. Psychopharmacology, 236(4):1159–1170, April, 2019. ![The effects of microdose LSD on time perception: a randomised, double-blind, placebo-controlled trial [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Methods We conducted a randomised, double-blind, placebo-controlled study contrasting oral administration of placebo with three microdoses of LSD (5, 10, and 20 μg) in older adults. Subjective drug effects were regularly recorded and interval timing was assessed using a temporal reproduction task spanning subsecond and suprasecond intervals. Results LSD conditions were not associated with any robust changes in self-report indices of perception, mentation, or concentration. LSD reliably produced over-reproduction of temporal intervals of 2000 ms and longer with these effects most pronounced in the 10 μg dose condition. Hierarchical regression analyses indicated that LSD-mediated over-reproduction was independent of marginal differences in self-reported drug effects across conditions. Conclusions These results suggest that microdose LSD produces temporal dilation of suprasecond intervals in the absence of subjective alterations of consciousness.
@article{yanakieva_effects_2019,
title = {The effects of microdose {LSD} on time perception: a randomised, double-blind, placebo-controlled trial},
volume = {236},
issn = {0033-3158, 1432-2072},
shorttitle = {The effects of microdose {LSD} on time perception},
url = {http://link.springer.com/10.1007/s00213-018-5119-x},
doi = {10.1007/s00213-018-5119-x},
abstract = {Methods We conducted a randomised, double-blind, placebo-controlled study contrasting oral administration of placebo with three microdoses of LSD (5, 10, and 20 μg) in older adults. Subjective drug effects were regularly recorded and interval timing was assessed using a temporal reproduction task spanning subsecond and suprasecond intervals.
Results LSD conditions were not associated with any robust changes in self-report indices of perception, mentation, or concentration. LSD reliably produced over-reproduction of temporal intervals of 2000 ms and longer with these effects most pronounced in the 10 μg dose condition. Hierarchical regression analyses indicated that LSD-mediated over-reproduction was independent of marginal differences in self-reported drug effects across conditions.
Conclusions These results suggest that microdose LSD produces temporal dilation of suprasecond intervals in the absence of subjective alterations of consciousness.},
language = {en},
number = {4},
urldate = {2024-05-03},
journal = {Psychopharmacology},
author = {Yanakieva, Steliana and Polychroni, Naya and Family, Neiloufar and Williams, Luke T. J. and Luke, David P. and Terhune, Devin B.},
month = apr,
year = {2019},
keywords = {L\&S},
pages = {1159--1170},
}
Downloads: 0
{"_id":"jJHaxQwW5GZjwrhGY","bibbaseid":"yanakieva-polychroni-family-williams-luke-terhune-theeffectsofmicrodoselsdontimeperceptionarandomiseddoubleblindplacebocontrolledtrial-2019","author_short":["Yanakieva, S.","Polychroni, N.","Family, N.","Williams, L. T. J.","Luke, D. P.","Terhune, D. B."],"bibdata":{"bibtype":"article","type":"article","title":"The effects of microdose LSD on time perception: a randomised, double-blind, placebo-controlled trial","volume":"236","issn":"0033-3158, 1432-2072","shorttitle":"The effects of microdose LSD on time perception","url":"http://link.springer.com/10.1007/s00213-018-5119-x","doi":"10.1007/s00213-018-5119-x","abstract":"Methods We conducted a randomised, double-blind, placebo-controlled study contrasting oral administration of placebo with three microdoses of LSD (5, 10, and 20 μg) in older adults. Subjective drug effects were regularly recorded and interval timing was assessed using a temporal reproduction task spanning subsecond and suprasecond intervals. Results LSD conditions were not associated with any robust changes in self-report indices of perception, mentation, or concentration. LSD reliably produced over-reproduction of temporal intervals of 2000 ms and longer with these effects most pronounced in the 10 μg dose condition. Hierarchical regression analyses indicated that LSD-mediated over-reproduction was independent of marginal differences in self-reported drug effects across conditions. Conclusions These results suggest that microdose LSD produces temporal dilation of suprasecond intervals in the absence of subjective alterations of consciousness.","language":"en","number":"4","urldate":"2024-05-03","journal":"Psychopharmacology","author":[{"propositions":[],"lastnames":["Yanakieva"],"firstnames":["Steliana"],"suffixes":[]},{"propositions":[],"lastnames":["Polychroni"],"firstnames":["Naya"],"suffixes":[]},{"propositions":[],"lastnames":["Family"],"firstnames":["Neiloufar"],"suffixes":[]},{"propositions":[],"lastnames":["Williams"],"firstnames":["Luke","T.","J."],"suffixes":[]},{"propositions":[],"lastnames":["Luke"],"firstnames":["David","P."],"suffixes":[]},{"propositions":[],"lastnames":["Terhune"],"firstnames":["Devin","B."],"suffixes":[]}],"month":"April","year":"2019","keywords":"L&S","pages":"1159–1170","bibtex":"@article{yanakieva_effects_2019,\n\ttitle = {The effects of microdose {LSD} on time perception: a randomised, double-blind, placebo-controlled trial},\n\tvolume = {236},\n\tissn = {0033-3158, 1432-2072},\n\tshorttitle = {The effects of microdose {LSD} on time perception},\n\turl = {http://link.springer.com/10.1007/s00213-018-5119-x},\n\tdoi = {10.1007/s00213-018-5119-x},\n\tabstract = {Methods We conducted a randomised, double-blind, placebo-controlled study contrasting oral administration of placebo with three microdoses of LSD (5, 10, and 20 μg) in older adults. Subjective drug effects were regularly recorded and interval timing was assessed using a temporal reproduction task spanning subsecond and suprasecond intervals.\nResults LSD conditions were not associated with any robust changes in self-report indices of perception, mentation, or concentration. LSD reliably produced over-reproduction of temporal intervals of 2000 ms and longer with these effects most pronounced in the 10 μg dose condition. Hierarchical regression analyses indicated that LSD-mediated over-reproduction was independent of marginal differences in self-reported drug effects across conditions.\nConclusions These results suggest that microdose LSD produces temporal dilation of suprasecond intervals in the absence of subjective alterations of consciousness.},\n\tlanguage = {en},\n\tnumber = {4},\n\turldate = {2024-05-03},\n\tjournal = {Psychopharmacology},\n\tauthor = {Yanakieva, Steliana and Polychroni, Naya and Family, Neiloufar and Williams, Luke T. J. and Luke, David P. and Terhune, Devin B.},\n\tmonth = apr,\n\tyear = {2019},\n\tkeywords = {L\\&S},\n\tpages = {1159--1170},\n}\n\n\n\n\n\n\n\n","author_short":["Yanakieva, S.","Polychroni, N.","Family, N.","Williams, L. T. J.","Luke, D. P.","Terhune, D. B."],"key":"yanakieva_effects_2019","id":"yanakieva_effects_2019","bibbaseid":"yanakieva-polychroni-family-williams-luke-terhune-theeffectsofmicrodoselsdontimeperceptionarandomiseddoubleblindplacebocontrolledtrial-2019","role":"author","urls":{"Paper":"http://link.springer.com/10.1007/s00213-018-5119-x"},"keyword":["L&S"],"metadata":{"authorlinks":{}},"html":""},"bibtype":"article","biburl":"https://bibbase.org/zotero/dishore","dataSources":["xoexFPcKZgur4xsCJ"],"keywords":["l&s"],"search_terms":["effects","microdose","lsd","time","perception","randomised","double","blind","placebo","controlled","trial","yanakieva","polychroni","family","williams","luke","terhune"],"title":"The effects of microdose LSD on time perception: a randomised, double-blind, placebo-controlled trial","year":2019}