Probabilistic reasoning by neurons. Yang, T. & Shadlen, M. N Nature, 2007.
doi  abstract   bibtex   
Our brains allow us to reason about alternatives and to make choices that are likely to pay off. Often there is no one correct answer, but instead one that is favoured simply because it is more likely to lead to reward. A variety of probabilistic classification tasks probe the covert strategies that humans use to decide among alternatives based on evidence that bears only probabilistically on outcome. Here we show that rhesus monkeys can also achieve such reasoning. We have trained two monkeys to choose between a pair of coloured targets after viewing four shapes, shown sequentially, that governed the probability that one of the targets would furnish reward. Monkeys learned to combine probabilistic information from the shape combinations. Moreover, neurons in the parietal cortex reveal the addition and subtraction of probabilistic quantities that underlie decision-making on this task.
@Article{Yang2007,
  author   = {Tianming Yang and Michael N Shadlen},
  journal  = {Nature},
  title    = {Probabilistic reasoning by neurons.},
  year     = {2007},
  abstract = {Our brains allow us to reason about alternatives and to make choices
	that are likely to pay off. Often there is no one correct answer,
	but instead one that is favoured simply because it is more likely
	to lead to reward. A variety of probabilistic classification tasks
	probe the covert strategies that humans use to decide among alternatives
	based on evidence that bears only probabilistically on outcome. Here
	we show that rhesus monkeys can also achieve such reasoning. We have
	trained two monkeys to choose between a pair of coloured targets
	after viewing four shapes, shown sequentially, that governed the
	probability that one of the targets would furnish reward. Monkeys
	learned to combine probabilistic information from the shape combinations.
	Moreover, neurons in the parietal cortex reveal the addition and
	subtraction of probabilistic quantities that underlie decision-making
	on this task.},
  doi      = {10.1038/nature05852},
  keywords = {17546027},
}

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