Time-Dependent Effects of Cryoablation for Renal Tumor on Overall and Split Renal Function. Yoshimatsu, R., Yamagami, T., Nishimori, M., Ogi, K., Murata, Y., Iwasa, H., Kajiwara, K., Yamanishi, T., Minamiguchi, H., Karashima, T., & Inoue, K. Journal of Vascular and Interventional Radiology, 30(3):460–465, March, 2019.
Paper doi abstract bibtex Purpose To evaluate the influence of percutaneous cryoablation for renal cell carcinoma on function of the affected kidney. Materials and Methods Between June 2016 and September 2017 at our institution, 12 inoperable patients underwent 15 cryoablation sessions for 17 small renal tumors. Of these, 9 patients who underwent 11 sessions of cryoablation were the focus of this study. For those patients, time-dependent changes in postoperative renal function were investigated by a retrospective review of clinical records. Evaluated were the estimated glomerular filtration rate (eGFR) and scintigraphy using 99m technetium-mercaptoacetyltriglycine (99mTc-MAG3) before and 1 week, 1–2 months, and more than 6 months after cryoablation. Results Mean baseline eGFR was 76.88 ± 29.82 mL/min/1.73 m2 (mean ± standard deviation; range, 23.4–112.5). Mean eGFR 1 week, 1–2 months, and more than 6 months after cryoablation were 74.56 ± 26.68 mL/min/1.73 m2 (21.0–101.1), 69.5 ± 25.28 mL/min/1.73 m2 (24.1–105.6), and 75.08 ± 26.25 mL/min/1.73 m2 (29.0–107.3), respectively. Changes were statistically insignificant (P = .6044, P = .6699, and P = .9038, respectively). Regarding split renal function, the mean baseline contribution of the affected kidney determined by 99mTc-MAG3 was 47.27% ± 6.14 (38.8%–57.0%). Mean contributions of the affected kidney 1 week after, 1–2 months after, and more than 6 months after cryoablation were 44.40% ± 5.37 (38.3%–53.6%), 44.57% ± 6.52 (34.35%–55.0%), and 45.41% ± 7.77 (34.4%–56.5%), respectively. Differences from baseline were significant for the earliest 2 periods (P = .0473 and P = .0334, respectively) but not the later period (P = .2532). Conclusions Results suggested that total renal function does not worsen after cryoablation; however, function of the affected kidney worsened after cryoablation but later partially recovered.
@article{yoshimatsu_time-dependent_2019,
title = {Time-{Dependent} {Effects} of {Cryoablation} for {Renal} {Tumor} on {Overall} and {Split} {Renal} {Function}},
volume = {30},
issn = {1051-0443},
url = {http://www.sciencedirect.com/science/article/pii/S1051044318316063},
doi = {10.1016/j.jvir.2018.10.017},
abstract = {Purpose
To evaluate the influence of percutaneous cryoablation for renal cell carcinoma on function of the affected kidney.
Materials and Methods
Between June 2016 and September 2017 at our institution, 12 inoperable patients underwent 15 cryoablation sessions for 17 small renal tumors. Of these, 9 patients who underwent 11 sessions of cryoablation were the focus of this study. For those patients, time-dependent changes in postoperative renal function were investigated by a retrospective review of clinical records. Evaluated were the estimated glomerular filtration rate (eGFR) and scintigraphy using 99m technetium-mercaptoacetyltriglycine (99mTc-MAG3) before and 1 week, 1–2 months, and more than 6 months after cryoablation.
Results
Mean baseline eGFR was 76.88 ± 29.82 mL/min/1.73 m2 (mean ± standard deviation; range, 23.4–112.5). Mean eGFR 1 week, 1–2 months, and more than 6 months after cryoablation were 74.56 ± 26.68 mL/min/1.73 m2 (21.0–101.1), 69.5 ± 25.28 mL/min/1.73 m2 (24.1–105.6), and 75.08 ± 26.25 mL/min/1.73 m2 (29.0–107.3), respectively. Changes were statistically insignificant (P = .6044, P = .6699, and P = .9038, respectively). Regarding split renal function, the mean baseline contribution of the affected kidney determined by 99mTc-MAG3 was 47.27\% ± 6.14 (38.8\%–57.0\%). Mean contributions of the affected kidney 1 week after, 1–2 months after, and more than 6 months after cryoablation were 44.40\% ± 5.37 (38.3\%–53.6\%), 44.57\% ± 6.52 (34.35\%–55.0\%), and 45.41\% ± 7.77 (34.4\%–56.5\%), respectively. Differences from baseline were significant for the earliest 2 periods (P = .0473 and P = .0334, respectively) but not the later period (P = .2532).
Conclusions
Results suggested that total renal function does not worsen after cryoablation; however, function of the affected kidney worsened after cryoablation but later partially recovered.},
number = {3},
urldate = {2019-03-02},
journal = {Journal of Vascular and Interventional Radiology},
author = {Yoshimatsu, Rika and Yamagami, Takuji and Nishimori, Miki and Ogi, Kenta and Murata, Yoriko and Iwasa, Hitomi and Kajiwara, Kenji and Yamanishi, Tomoaki and Minamiguchi, Hiroki and Karashima, Takashi and Inoue, Keiji},
month = mar,
year = {2019},
pages = {460--465},
}
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{"_id":"GPNTfkcPu3MWnTQNc","bibbaseid":"yoshimatsu-yamagami-nishimori-ogi-murata-iwasa-kajiwara-yamanishi-etal-timedependenteffectsofcryoablationforrenaltumoronoverallandsplitrenalfunction-2019","downloads":0,"creationDate":"2019-03-08T19:02:45.680Z","title":"Time-Dependent Effects of Cryoablation for Renal Tumor on Overall and Split Renal Function","author_short":["Yoshimatsu, R.","Yamagami, T.","Nishimori, M.","Ogi, K.","Murata, Y.","Iwasa, H.","Kajiwara, K.","Yamanishi, T.","Minamiguchi, H.","Karashima, T.","Inoue, K."],"year":2019,"bibtype":"article","biburl":"https://bibbase.org/zotero/sannpeterson","bibdata":{"bibtype":"article","type":"article","title":"Time-Dependent Effects of Cryoablation for Renal Tumor on Overall and Split Renal Function","volume":"30","issn":"1051-0443","url":"http://www.sciencedirect.com/science/article/pii/S1051044318316063","doi":"10.1016/j.jvir.2018.10.017","abstract":"Purpose To evaluate the influence of percutaneous cryoablation for renal cell carcinoma on function of the affected kidney. Materials and Methods Between June 2016 and September 2017 at our institution, 12 inoperable patients underwent 15 cryoablation sessions for 17 small renal tumors. Of these, 9 patients who underwent 11 sessions of cryoablation were the focus of this study. For those patients, time-dependent changes in postoperative renal function were investigated by a retrospective review of clinical records. Evaluated were the estimated glomerular filtration rate (eGFR) and scintigraphy using 99m technetium-mercaptoacetyltriglycine (99mTc-MAG3) before and 1 week, 1–2 months, and more than 6 months after cryoablation. Results Mean baseline eGFR was 76.88 ± 29.82 mL/min/1.73 m2 (mean ± standard deviation; range, 23.4–112.5). Mean eGFR 1 week, 1–2 months, and more than 6 months after cryoablation were 74.56 ± 26.68 mL/min/1.73 m2 (21.0–101.1), 69.5 ± 25.28 mL/min/1.73 m2 (24.1–105.6), and 75.08 ± 26.25 mL/min/1.73 m2 (29.0–107.3), respectively. Changes were statistically insignificant (P = .6044, P = .6699, and P = .9038, respectively). Regarding split renal function, the mean baseline contribution of the affected kidney determined by 99mTc-MAG3 was 47.27% ± 6.14 (38.8%–57.0%). Mean contributions of the affected kidney 1 week after, 1–2 months after, and more than 6 months after cryoablation were 44.40% ± 5.37 (38.3%–53.6%), 44.57% ± 6.52 (34.35%–55.0%), and 45.41% ± 7.77 (34.4%–56.5%), respectively. Differences from baseline were significant for the earliest 2 periods (P = .0473 and P = .0334, respectively) but not the later period (P = .2532). Conclusions Results suggested that total renal function does not worsen after cryoablation; however, function of the affected kidney worsened after cryoablation but later partially recovered.","number":"3","urldate":"2019-03-02","journal":"Journal of Vascular and Interventional Radiology","author":[{"propositions":[],"lastnames":["Yoshimatsu"],"firstnames":["Rika"],"suffixes":[]},{"propositions":[],"lastnames":["Yamagami"],"firstnames":["Takuji"],"suffixes":[]},{"propositions":[],"lastnames":["Nishimori"],"firstnames":["Miki"],"suffixes":[]},{"propositions":[],"lastnames":["Ogi"],"firstnames":["Kenta"],"suffixes":[]},{"propositions":[],"lastnames":["Murata"],"firstnames":["Yoriko"],"suffixes":[]},{"propositions":[],"lastnames":["Iwasa"],"firstnames":["Hitomi"],"suffixes":[]},{"propositions":[],"lastnames":["Kajiwara"],"firstnames":["Kenji"],"suffixes":[]},{"propositions":[],"lastnames":["Yamanishi"],"firstnames":["Tomoaki"],"suffixes":[]},{"propositions":[],"lastnames":["Minamiguchi"],"firstnames":["Hiroki"],"suffixes":[]},{"propositions":[],"lastnames":["Karashima"],"firstnames":["Takashi"],"suffixes":[]},{"propositions":[],"lastnames":["Inoue"],"firstnames":["Keiji"],"suffixes":[]}],"month":"March","year":"2019","pages":"460–465","bibtex":"@article{yoshimatsu_time-dependent_2019,\n\ttitle = {Time-{Dependent} {Effects} of {Cryoablation} for {Renal} {Tumor} on {Overall} and {Split} {Renal} {Function}},\n\tvolume = {30},\n\tissn = {1051-0443},\n\turl = {http://www.sciencedirect.com/science/article/pii/S1051044318316063},\n\tdoi = {10.1016/j.jvir.2018.10.017},\n\tabstract = {Purpose\nTo evaluate the influence of percutaneous cryoablation for renal cell carcinoma on function of the affected kidney.\nMaterials and Methods\nBetween June 2016 and September 2017 at our institution, 12 inoperable patients underwent 15 cryoablation sessions for 17 small renal tumors. Of these, 9 patients who underwent 11 sessions of cryoablation were the focus of this study. For those patients, time-dependent changes in postoperative renal function were investigated by a retrospective review of clinical records. Evaluated were the estimated glomerular filtration rate (eGFR) and scintigraphy using 99m technetium-mercaptoacetyltriglycine (99mTc-MAG3) before and 1 week, 1–2 months, and more than 6 months after cryoablation.\nResults\nMean baseline eGFR was 76.88 ± 29.82 mL/min/1.73 m2 (mean ± standard deviation; range, 23.4–112.5). Mean eGFR 1 week, 1–2 months, and more than 6 months after cryoablation were 74.56 ± 26.68 mL/min/1.73 m2 (21.0–101.1), 69.5 ± 25.28 mL/min/1.73 m2 (24.1–105.6), and 75.08 ± 26.25 mL/min/1.73 m2 (29.0–107.3), respectively. Changes were statistically insignificant (P = .6044, P = .6699, and P = .9038, respectively). Regarding split renal function, the mean baseline contribution of the affected kidney determined by 99mTc-MAG3 was 47.27\\% ± 6.14 (38.8\\%–57.0\\%). Mean contributions of the affected kidney 1 week after, 1–2 months after, and more than 6 months after cryoablation were 44.40\\% ± 5.37 (38.3\\%–53.6\\%), 44.57\\% ± 6.52 (34.35\\%–55.0\\%), and 45.41\\% ± 7.77 (34.4\\%–56.5\\%), respectively. Differences from baseline were significant for the earliest 2 periods (P = .0473 and P = .0334, respectively) but not the later period (P = .2532).\nConclusions\nResults suggested that total renal function does not worsen after cryoablation; however, function of the affected kidney worsened after cryoablation but later partially recovered.},\n\tnumber = {3},\n\turldate = {2019-03-02},\n\tjournal = {Journal of Vascular and Interventional Radiology},\n\tauthor = {Yoshimatsu, Rika and Yamagami, Takuji and Nishimori, Miki and Ogi, Kenta and Murata, Yoriko and Iwasa, Hitomi and Kajiwara, Kenji and Yamanishi, Tomoaki and Minamiguchi, Hiroki and Karashima, Takashi and Inoue, Keiji},\n\tmonth = mar,\n\tyear = {2019},\n\tpages = {460--465},\n}\n\n","author_short":["Yoshimatsu, R.","Yamagami, T.","Nishimori, M.","Ogi, K.","Murata, Y.","Iwasa, H.","Kajiwara, K.","Yamanishi, T.","Minamiguchi, H.","Karashima, T.","Inoue, K."],"key":"yoshimatsu_time-dependent_2019","id":"yoshimatsu_time-dependent_2019","bibbaseid":"yoshimatsu-yamagami-nishimori-ogi-murata-iwasa-kajiwara-yamanishi-etal-timedependenteffectsofcryoablationforrenaltumoronoverallandsplitrenalfunction-2019","role":"author","urls":{"Paper":"http://www.sciencedirect.com/science/article/pii/S1051044318316063"},"metadata":{"authorlinks":{}},"html":""},"search_terms":["time","dependent","effects","cryoablation","renal","tumor","overall","split","renal","function","yoshimatsu","yamagami","nishimori","ogi","murata","iwasa","kajiwara","yamanishi","minamiguchi","karashima","inoue"],"keywords":[],"authorIDs":[],"dataSources":["JPAoq8b4ppzXj5XYZ"]}