A Plasmonic DNAzyme Strategy for Point-of-Care Genetic Detection of Infectious Pathogens. Zagorovsky, K. & Chan, W. C. W. Angewandte Chemie International Edition, 52(11):3168–3171, 2013. _eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201208715Paper Paper doi abstract bibtex Always use detection: Signal amplification from DNAzymes (see scheme) was combined with gold nanoparticles (GNPs) to give a simple and sensitive colorimetric assay for various genetic targets. The assay has 50 pM sensitivity without the need for purification steps and can detect multiple targets in parallel. This was applied to rapidly detect gonorrhea, syphilis, malaria, and hepatitis B infections.
@article{zagorovsky_plasmonic_2013-1,
title = {A {Plasmonic} {DNAzyme} {Strategy} for {Point}-of-{Care} {Genetic} {Detection} of {Infectious} {Pathogens}},
volume = {52},
issn = {1521-3773},
url = {http://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201208715},
doi = {10.1002/anie.201208715},
abstract = {Always use detection: Signal amplification from DNAzymes (see scheme) was combined with gold nanoparticles (GNPs) to give a simple and sensitive colorimetric assay for various genetic targets. The assay has 50 pM sensitivity without the need for purification steps and can detect multiple targets in parallel. This was applied to rapidly detect gonorrhea, syphilis, malaria, and hepatitis B infections.},
number = {11},
urldate = {2021-11-06},
journal = {Angewandte Chemie International Edition},
author = {Zagorovsky, Kyryl and Chan, Warren C. W.},
year = {2013},
note = {\_eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201208715},
keywords = {biosensors, DNA recognition, DNAzymes, nanoparticles, surface plasmon resonance},
pages = {3168--3171},
file = {Full Text PDF:files/2061/Zagorovsky and Chan - 2013 - A Plasmonic DNAzyme Strategy for Point-of-Care Gen.pdf:application/pdf;Snapshot:files/2064/anie.html:text/html},
url_Paper = {https://inbs.med.utoronto.ca/wp-content/uploads/2020/08/anie.201208715.pdf}
}
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