Antibodies to Seasonal Coronaviruses Rarely Cross-React With SARS-CoV-2: Findings From an African Birth Cohort. Zar, H. J, Nicol, M. P, MacGinty, R., Workman, L., Petersen, W., Johnson, M., & Goldblatt, D. The Pediatric infectious disease journal, 40(12):e516–e519, Pediatr Infect Dis J, dec, 2021.
Paper doi abstract bibtex Antibodies to seasonal human-coronaviruses (sHCoV) may cross-protect against SARS-CoV-2. We investigated antibody responses in biobanked serum obtained before the pandemic from infants with polymerase chain reaction-confirmed sHCoV. Among 141 samples with antibodies to sHCoV, 4 (2.8%) were positive for SARS-CoV-2-S1 and 8 (5.7%) for SARS-CoV-2-S2. Antibodies to sHCoV rarely cross-react with SARS-CoV-2 antigens and are unlikely to account for mild pediatric illness.
@article{Zar2021,
abstract = {Antibodies to seasonal human-coronaviruses (sHCoV) may cross-protect against SARS-CoV-2. We investigated antibody responses in biobanked serum obtained before the pandemic from infants with polymerase chain reaction-confirmed sHCoV. Among 141 samples with antibodies to sHCoV, 4 (2.8{\%}) were positive for SARS-CoV-2-S1 and 8 (5.7{\%}) for SARS-CoV-2-S2. Antibodies to sHCoV rarely cross-react with SARS-CoV-2 antigens and are unlikely to account for mild pediatric illness.},
author = {Zar, Heather J and Nicol, Mark P and MacGinty, Rae and Workman, Lesley and Petersen, Wonita and Johnson, Marina and Goldblatt, David},
doi = {10.1097/INF.0000000000003325},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Zar et al. - 2021 - Antibodies to Seasonal Coronaviruses Rarely Cross-React With SARS-CoV-2 Findings From an African Birth Cohort.pdf:pdf},
issn = {1532-0987},
journal = {The Pediatric infectious disease journal},
keywords = {David Goldblatt,Heather J Zar,MEDLINE,Mark P Nicol,NCBI,NIH,NLM,National Center for Biotechnology Information,National Institutes of Health,National Library of Medicine,OA,OA{\_}PMC,PMC8575088,PubMed Abstract,doi:10.1097/INF.0000000000003325,fund{\_}ack,original,pmid:34533491},
mendeley-tags = {OA,OA{\_}PMC,fund{\_}ack,original},
month = {dec},
number = {12},
pages = {e516--e519},
pmid = {34533491},
publisher = {Pediatr Infect Dis J},
title = {{Antibodies to Seasonal Coronaviruses Rarely Cross-React With SARS-CoV-2: Findings From an African Birth Cohort.}},
url = {https://pubmed.ncbi.nlm.nih.gov/34533491/ http://www.ncbi.nlm.nih.gov/pubmed/34533491 http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC8575088},
volume = {40},
year = {2021}
}
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