Developing clinical phenotype data collection standards for research in Africa. Zass, L., Johnston, K., Benkahla, A., Chaouch, M., Kumuthini, J., Radouani, F., Mwita, L. A., Alsayed, N., Allie, T., Sathan, D., Masamu, U., Seuneu Tchamga, M. S., Tamuhla, T., Samtal, C., Nembaware, V., Gill, Z., Ahmed, S., Hamdi, Y., Fadlelmola, F., Tiffin, N., & Mulder, N. Global Health, Epidemiology and Genomics, 2023:6693323, Hindawi, 2023. ![Developing clinical phenotype data collection standards for research in Africa [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Modern biomedical research is characterised by its high-throughput and interdisciplinary nature. Multiproject and consortium-based collaborations requiring meaningful analysis of multiple heterogeneous phenotypic datasets have become the norm; however, such analysis remains a challenge in many regions across the world. An increasing number of data harmonisation efforts are being undertaken by multistudy collaborations through either prospective standardised phenotype data collection or retrospective phenotype harmonisation. In this regard, the Phenotype Harmonisation Working Group (PHWG) of the Human Heredity and Health in Africa (H3Africa) consortium aimed to facilitate phenotype standardisation by both promoting the use of existing data collection standards (hosted by PhenX), adapting existing data collection standards for appropriate use in low- and middle-income regions such as Africa, and developing novel data collection standards where relevant gaps were identified. Ultimately, the PHWG produced 11 data collection kits, consisting of 82 protocols, 38 of which were existing protocols, 17 were adapted, and 27 were novel protocols. The data collection kits will facilitate phenotype standardisation and harmonisation not only in Africa but also across the larger research community. In addition, the PHWG aims to feed back adapted and novel protocols to existing reference platforms such as PhenX.
@article{Zass2023,
abstract = {Modern biomedical research is characterised by its high-throughput and interdisciplinary nature. Multiproject and consortium-based collaborations requiring meaningful analysis of multiple heterogeneous phenotypic datasets have become the norm; however, such analysis remains a challenge in many regions across the world. An increasing number of data harmonisation efforts are being undertaken by multistudy collaborations through either prospective standardised phenotype data collection or retrospective phenotype harmonisation. In this regard, the Phenotype Harmonisation Working Group (PHWG) of the Human Heredity and Health in Africa (H3Africa) consortium aimed to facilitate phenotype standardisation by both promoting the use of existing data collection standards (hosted by PhenX), adapting existing data collection standards for appropriate use in low- and middle-income regions such as Africa, and developing novel data collection standards where relevant gaps were identified. Ultimately, the PHWG produced 11 data collection kits, consisting of 82 protocols, 38 of which were existing protocols, 17 were adapted, and 27 were novel protocols. The data collection kits will facilitate phenotype standardisation and harmonisation not only in Africa but also across the larger research community. In addition, the PHWG aims to feed back adapted and novel protocols to existing reference platforms such as PhenX.},
author = {Zass, Lyndon and Johnston, Katherine and Benkahla, Alia and Chaouch, Melek and Kumuthini, Judit and Radouani, Fouzia and Mwita, Liberata Alexander and Alsayed, Nihad and Allie, Taryn and Sathan, Dassen and Masamu, Upendo and {Seuneu Tchamga}, Milaine Sergine and Tamuhla, Tsaone and Samtal, Chaimae and Nembaware, Victoria and Gill, Zoe and Ahmed, Samah and Hamdi, Yosr and Fadlelmola, Faisal and Tiffin, Nicki and Mulder, Nicola},
doi = {10.1155/2023/6693323},
editor = {Mboowa, Gerald},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Zass et al. - 2023 - Developing clinical phenotype data collection standards for research in Africa.pdf:pdf},
issn = {2054-4200},
journal = {Global Health, Epidemiology and Genomics},
keywords = {OA,fund{\_}not{\_}ack,original},
mendeley-tags = {OA,fund{\_}not{\_}ack,original},
pages = {6693323},
publisher = {Hindawi},
title = {{Developing clinical phenotype data collection standards for research in Africa}},
url = {https://doi.org/10.1155/2023/6693323},
volume = {2023},
year = {2023}
}
Downloads: 0
{"_id":"keWZfPvEN3Ze9p3JR","bibbaseid":"zass-johnston-benkahla-chaouch-kumuthini-radouani-mwita-alsayed-etal-developingclinicalphenotypedatacollectionstandardsforresearchinafrica-2023","author_short":["Zass, L.","Johnston, K.","Benkahla, A.","Chaouch, M.","Kumuthini, J.","Radouani, F.","Mwita, L. A.","Alsayed, N.","Allie, T.","Sathan, D.","Masamu, U.","Seuneu Tchamga, M. S.","Tamuhla, T.","Samtal, C.","Nembaware, V.","Gill, Z.","Ahmed, S.","Hamdi, Y.","Fadlelmola, F.","Tiffin, N.","Mulder, N."],"bibdata":{"bibtype":"article","type":"article","abstract":"Modern biomedical research is characterised by its high-throughput and interdisciplinary nature. Multiproject and consortium-based collaborations requiring meaningful analysis of multiple heterogeneous phenotypic datasets have become the norm; however, such analysis remains a challenge in many regions across the world. An increasing number of data harmonisation efforts are being undertaken by multistudy collaborations through either prospective standardised phenotype data collection or retrospective phenotype harmonisation. In this regard, the Phenotype Harmonisation Working Group (PHWG) of the Human Heredity and Health in Africa (H3Africa) consortium aimed to facilitate phenotype standardisation by both promoting the use of existing data collection standards (hosted by PhenX), adapting existing data collection standards for appropriate use in low- and middle-income regions such as Africa, and developing novel data collection standards where relevant gaps were identified. Ultimately, the PHWG produced 11 data collection kits, consisting of 82 protocols, 38 of which were existing protocols, 17 were adapted, and 27 were novel protocols. The data collection kits will facilitate phenotype standardisation and harmonisation not only in Africa but also across the larger research community. In addition, the PHWG aims to feed back adapted and novel protocols to existing reference platforms such as PhenX.","author":[{"propositions":[],"lastnames":["Zass"],"firstnames":["Lyndon"],"suffixes":[]},{"propositions":[],"lastnames":["Johnston"],"firstnames":["Katherine"],"suffixes":[]},{"propositions":[],"lastnames":["Benkahla"],"firstnames":["Alia"],"suffixes":[]},{"propositions":[],"lastnames":["Chaouch"],"firstnames":["Melek"],"suffixes":[]},{"propositions":[],"lastnames":["Kumuthini"],"firstnames":["Judit"],"suffixes":[]},{"propositions":[],"lastnames":["Radouani"],"firstnames":["Fouzia"],"suffixes":[]},{"propositions":[],"lastnames":["Mwita"],"firstnames":["Liberata","Alexander"],"suffixes":[]},{"propositions":[],"lastnames":["Alsayed"],"firstnames":["Nihad"],"suffixes":[]},{"propositions":[],"lastnames":["Allie"],"firstnames":["Taryn"],"suffixes":[]},{"propositions":[],"lastnames":["Sathan"],"firstnames":["Dassen"],"suffixes":[]},{"propositions":[],"lastnames":["Masamu"],"firstnames":["Upendo"],"suffixes":[]},{"propositions":[],"lastnames":["Seuneu Tchamga"],"firstnames":["Milaine","Sergine"],"suffixes":[]},{"propositions":[],"lastnames":["Tamuhla"],"firstnames":["Tsaone"],"suffixes":[]},{"propositions":[],"lastnames":["Samtal"],"firstnames":["Chaimae"],"suffixes":[]},{"propositions":[],"lastnames":["Nembaware"],"firstnames":["Victoria"],"suffixes":[]},{"propositions":[],"lastnames":["Gill"],"firstnames":["Zoe"],"suffixes":[]},{"propositions":[],"lastnames":["Ahmed"],"firstnames":["Samah"],"suffixes":[]},{"propositions":[],"lastnames":["Hamdi"],"firstnames":["Yosr"],"suffixes":[]},{"propositions":[],"lastnames":["Fadlelmola"],"firstnames":["Faisal"],"suffixes":[]},{"propositions":[],"lastnames":["Tiffin"],"firstnames":["Nicki"],"suffixes":[]},{"propositions":[],"lastnames":["Mulder"],"firstnames":["Nicola"],"suffixes":[]}],"doi":"10.1155/2023/6693323","editor":[{"propositions":[],"lastnames":["Mboowa"],"firstnames":["Gerald"],"suffixes":[]}],"file":":C$\\$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Zass et al. - 2023 - Developing clinical phenotype data collection standards for research in Africa.pdf:pdf","issn":"2054-4200","journal":"Global Health, Epidemiology and Genomics","keywords":"OA,fund_not_ack,original","mendeley-tags":"OA,fund_not_ack,original","pages":"6693323","publisher":"Hindawi","title":"Developing clinical phenotype data collection standards for research in Africa","url":"https://doi.org/10.1155/2023/6693323","volume":"2023","year":"2023","bibtex":"@article{Zass2023,\r\nabstract = {Modern biomedical research is characterised by its high-throughput and interdisciplinary nature. Multiproject and consortium-based collaborations requiring meaningful analysis of multiple heterogeneous phenotypic datasets have become the norm; however, such analysis remains a challenge in many regions across the world. An increasing number of data harmonisation efforts are being undertaken by multistudy collaborations through either prospective standardised phenotype data collection or retrospective phenotype harmonisation. In this regard, the Phenotype Harmonisation Working Group (PHWG) of the Human Heredity and Health in Africa (H3Africa) consortium aimed to facilitate phenotype standardisation by both promoting the use of existing data collection standards (hosted by PhenX), adapting existing data collection standards for appropriate use in low- and middle-income regions such as Africa, and developing novel data collection standards where relevant gaps were identified. Ultimately, the PHWG produced 11 data collection kits, consisting of 82 protocols, 38 of which were existing protocols, 17 were adapted, and 27 were novel protocols. The data collection kits will facilitate phenotype standardisation and harmonisation not only in Africa but also across the larger research community. In addition, the PHWG aims to feed back adapted and novel protocols to existing reference platforms such as PhenX.},\r\nauthor = {Zass, Lyndon and Johnston, Katherine and Benkahla, Alia and Chaouch, Melek and Kumuthini, Judit and Radouani, Fouzia and Mwita, Liberata Alexander and Alsayed, Nihad and Allie, Taryn and Sathan, Dassen and Masamu, Upendo and {Seuneu Tchamga}, Milaine Sergine and Tamuhla, Tsaone and Samtal, Chaimae and Nembaware, Victoria and Gill, Zoe and Ahmed, Samah and Hamdi, Yosr and Fadlelmola, Faisal and Tiffin, Nicki and Mulder, Nicola},\r\ndoi = {10.1155/2023/6693323},\r\neditor = {Mboowa, Gerald},\r\nfile = {:C$\\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Zass et al. - 2023 - Developing clinical phenotype data collection standards for research in Africa.pdf:pdf},\r\nissn = {2054-4200},\r\njournal = {Global Health, Epidemiology and Genomics},\r\nkeywords = {OA,fund{\\_}not{\\_}ack,original},\r\nmendeley-tags = {OA,fund{\\_}not{\\_}ack,original},\r\npages = {6693323},\r\npublisher = {Hindawi},\r\ntitle = {{Developing clinical phenotype data collection standards for research in Africa}},\r\nurl = {https://doi.org/10.1155/2023/6693323},\r\nvolume = {2023},\r\nyear = {2023}\r\n}\r\n","author_short":["Zass, L.","Johnston, K.","Benkahla, A.","Chaouch, M.","Kumuthini, J.","Radouani, F.","Mwita, L. A.","Alsayed, N.","Allie, T.","Sathan, D.","Masamu, U.","Seuneu Tchamga, M. S.","Tamuhla, T.","Samtal, C.","Nembaware, V.","Gill, Z.","Ahmed, S.","Hamdi, Y.","Fadlelmola, F.","Tiffin, N.","Mulder, N."],"editor_short":["Mboowa, G."],"key":"Zass2023","id":"Zass2023","bibbaseid":"zass-johnston-benkahla-chaouch-kumuthini-radouani-mwita-alsayed-etal-developingclinicalphenotypedatacollectionstandardsforresearchinafrica-2023","role":"author","urls":{"Paper":"https://doi.org/10.1155/2023/6693323"},"keyword":["OA","fund_not_ack","original"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://drive.google.com/uc?export=download&id=1-JLqZ7RwZ3VC2d6ErLGHAtOeMRS_7GCz","dataSources":["Krmt6gt9ktB2s6ARh"],"keywords":["oa","fund_not_ack","original"],"search_terms":["developing","clinical","phenotype","data","collection","standards","research","africa","zass","johnston","benkahla","chaouch","kumuthini","radouani","mwita","alsayed","allie","sathan","masamu","seuneu tchamga","tamuhla","samtal","nembaware","gill","ahmed","hamdi","fadlelmola","tiffin","mulder"],"title":"Developing clinical phenotype data collection standards for research in Africa","year":2023}