Peripheral Hypoarousal but Not Preparation-Vigilance Impairment Endures in ADHD Remission. James, S., Cheung, C., H., M., Rommel, A., McLoughlin, G., Brandeis, D., Banaschewski, T., Asherson, P., & Kuntsi, J. Journal of Attention Disorders, SAGE Publications, 3, 2017.
Peripheral Hypoarousal but Not Preparation-Vigilance Impairment Endures in ADHD Remission [pdf]Paper  Peripheral Hypoarousal but Not Preparation-Vigilance Impairment Endures in ADHD Remission [link]Website  doi  abstract   bibtex   
Objective: This study investigates whether impairments associated with persistent ADHD—impaired attention allocation (P3 amplitude), peripheral hypoarousal (skin conductance level [SCL]), and adjustment in preparatory state (contingent negative variation [CNV])—reflect enduring deficits unrelated to ADHD outcome or are markers of ADHD remission. Method: Young people with childhood ADHD (73 persisters and 18 remitters) and 144 controls were compared on neurophysiological measures during two conditions (baseline and fast-incentive) of a four-choice reaction time task. Results: ADHD remitters differed from persisters, and were indistinguishable from controls, on baseline P3 amplitude and fast-incentive CNV amplitude (p ≤ .05). ADHD remitters differed from controls (p ≤ .01), and were indistinguishable from persisters (p > .05), on baseline SCL. Conclusion: Preparation-vigilance measures were markers of ADHD remission, confirming previous findings with other measures. Yet, SCL-measured peripheral hypoarousal ...

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