Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1. Joseph, S., Kwan, A., Mackay, J., Cubeddu, L., & Matthews, J. Biomolecular NMR Assignments, 8(1):141-144, 2014. doi abstract bibtex The transcriptional regulator LMO4 and the transcription factor DEAF-1 are both essential for brain and skeletal development. They are also implicated in human breast cancers; overexpression of LMO4 is an indicator of poor prognosis, and overexpression of DEAF-1 promotes epithelial breast cell proliferation. We have generated a stable LMO4-DEAF-1 complex comprising the C-terminal LIM domain of LMO4 and an intrinsically disordered LMO4-interaction domain from DEAF-1 tethered by a glycine/serine linker. Here we report the 1H, 15N and 13C assignments of this construct. Analysis of the assignments indicates the presence of structure in the DEAF-1 part of the complex supporting the presence of a physical interaction between the two proteins. © 2013 Springer Science+Business Media Dordrecht.
@article{
title = {Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1},
type = {article},
year = {2014},
pages = {141-144},
volume = {8},
id = {a64344fa-3b32-37f0-b1e1-f7b7ad8cbfd8},
created = {2023-01-10T01:44:42.330Z},
file_attached = {false},
profile_id = {a5a2ab6f-a8b5-3db6-97bc-618752ee4386},
group_id = {bc1ab1d4-9e57-37e6-9fb5-435fca0ee9d2},
last_modified = {2023-01-10T01:44:42.330Z},
read = {false},
starred = {false},
authored = {false},
confirmed = {false},
hidden = {false},
private_publication = {false},
abstract = {The transcriptional regulator LMO4 and the transcription factor DEAF-1 are both essential for brain and skeletal development. They are also implicated in human breast cancers; overexpression of LMO4 is an indicator of poor prognosis, and overexpression of DEAF-1 promotes epithelial breast cell proliferation. We have generated a stable LMO4-DEAF-1 complex comprising the C-terminal LIM domain of LMO4 and an intrinsically disordered LMO4-interaction domain from DEAF-1 tethered by a glycine/serine linker. Here we report the 1H, 15N and 13C assignments of this construct. Analysis of the assignments indicates the presence of structure in the DEAF-1 part of the complex supporting the presence of a physical interaction between the two proteins. © 2013 Springer Science+Business Media Dordrecht.},
bibtype = {article},
author = {Joseph, S. and Kwan, A.H.Y. and Mackay, J.P. and Cubeddu, L. and Matthews, J.M.},
doi = {10.1007/s12104-013-9470-x},
journal = {Biomolecular NMR Assignments},
number = {1}
}
Downloads: 0
{"_id":"F5WdKb4mnjfkxyTSY","bibbaseid":"joseph-kwan-mackay-cubeddu-matthews-backboneandsidechainassignmentsofatetheredcomplexbetweenlmo4anddeaf1-2014","authorIDs":["2Qc7yqmurPnGGpzkn","7xJPhTejQw7DNx2JR","BxZ4FTiTWXBJXvbaJ","CTpZTf4H3KET74jfr","Fon2uYg2vazgX9iJ6","JpXs8KwoKh8kauTxR","NjvEPsMvAHkoYtcaT","PQdWhPCpDe6wMYLCn","QptbNaef4ndCqyhZC","TmniPoAbJegeLCDLF","WnWSzNYsKhgzZyqef","ZTncL5PqZZ6RafCsL","Zs8wHzF6x3Hv6kFr5","aMiJWoXgj2f2jewLf","bMTAsCuJH7tNPP2A4","dL3rzKFFDKotEKQwz","hTunoKM2cJF7J3wAc","oRss7sMWLWQKecaGK","p4oatMDQk8y87x3WP","tkCAtYagtsqtcwsNv","zpBqmFpnWu3QfCjDk"],"author_short":["Joseph, S.","Kwan, A.","Mackay, J.","Cubeddu, L.","Matthews, J."],"bibdata":{"title":"Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1","type":"article","year":"2014","pages":"141-144","volume":"8","id":"a64344fa-3b32-37f0-b1e1-f7b7ad8cbfd8","created":"2023-01-10T01:44:42.330Z","file_attached":false,"profile_id":"a5a2ab6f-a8b5-3db6-97bc-618752ee4386","group_id":"bc1ab1d4-9e57-37e6-9fb5-435fca0ee9d2","last_modified":"2023-01-10T01:44:42.330Z","read":false,"starred":false,"authored":false,"confirmed":false,"hidden":false,"private_publication":false,"abstract":"The transcriptional regulator LMO4 and the transcription factor DEAF-1 are both essential for brain and skeletal development. They are also implicated in human breast cancers; overexpression of LMO4 is an indicator of poor prognosis, and overexpression of DEAF-1 promotes epithelial breast cell proliferation. We have generated a stable LMO4-DEAF-1 complex comprising the C-terminal LIM domain of LMO4 and an intrinsically disordered LMO4-interaction domain from DEAF-1 tethered by a glycine/serine linker. Here we report the 1H, 15N and 13C assignments of this construct. Analysis of the assignments indicates the presence of structure in the DEAF-1 part of the complex supporting the presence of a physical interaction between the two proteins. © 2013 Springer Science+Business Media Dordrecht.","bibtype":"article","author":"Joseph, S. and Kwan, A.H.Y. and Mackay, J.P. and Cubeddu, L. and Matthews, J.M.","doi":"10.1007/s12104-013-9470-x","journal":"Biomolecular NMR Assignments","number":"1","bibtex":"@article{\n title = {Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1},\n type = {article},\n year = {2014},\n pages = {141-144},\n volume = {8},\n id = {a64344fa-3b32-37f0-b1e1-f7b7ad8cbfd8},\n created = {2023-01-10T01:44:42.330Z},\n file_attached = {false},\n profile_id = {a5a2ab6f-a8b5-3db6-97bc-618752ee4386},\n group_id = {bc1ab1d4-9e57-37e6-9fb5-435fca0ee9d2},\n last_modified = {2023-01-10T01:44:42.330Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {false},\n hidden = {false},\n private_publication = {false},\n abstract = {The transcriptional regulator LMO4 and the transcription factor DEAF-1 are both essential for brain and skeletal development. They are also implicated in human breast cancers; overexpression of LMO4 is an indicator of poor prognosis, and overexpression of DEAF-1 promotes epithelial breast cell proliferation. We have generated a stable LMO4-DEAF-1 complex comprising the C-terminal LIM domain of LMO4 and an intrinsically disordered LMO4-interaction domain from DEAF-1 tethered by a glycine/serine linker. Here we report the 1H, 15N and 13C assignments of this construct. Analysis of the assignments indicates the presence of structure in the DEAF-1 part of the complex supporting the presence of a physical interaction between the two proteins. © 2013 Springer Science+Business Media Dordrecht.},\n bibtype = {article},\n author = {Joseph, S. and Kwan, A.H.Y. and Mackay, J.P. and Cubeddu, L. and Matthews, J.M.},\n doi = {10.1007/s12104-013-9470-x},\n journal = {Biomolecular NMR Assignments},\n number = {1}\n}","author_short":["Joseph, S.","Kwan, A.","Mackay, J.","Cubeddu, L.","Matthews, J."],"biburl":"https://bibbase.org/service/mendeley/a5a2ab6f-a8b5-3db6-97bc-618752ee4386","bibbaseid":"joseph-kwan-mackay-cubeddu-matthews-backboneandsidechainassignmentsofatetheredcomplexbetweenlmo4anddeaf1-2014","role":"author","urls":{},"metadata":{"authorlinks":{"mackay, j":"https://bibbase.org/service/mendeley/a5a2ab6f-a8b5-3db6-97bc-618752ee4386/group/bc1ab1d4-9e57-37e6-9fb5-435fca0ee9d2","kwan, a":"https://www.kwanlabusyd.com/publications-1"}},"downloads":0},"bibtype":"article","creationDate":"2020-07-10T06:21:14.919Z","downloads":0,"keywords":[],"search_terms":["backbone","side","chain","assignments","tethered","complex","between","lmo4","deaf","joseph","kwan","mackay","cubeddu","matthews"],"title":"Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1","year":2014,"biburl":"https://bibbase.org/service/mendeley/a5a2ab6f-a8b5-3db6-97bc-618752ee4386","dataSources":["QNo3CKhtog6c3sh7Y","ya2CyA73rpZseyrZ8","Qyiuzjmxwb6Qg6BFv","ToyCPY2rxgiQ4m4by","rdWS9Da3o8ATA9vPu","GHkD7mCKXmQCzS4W8","4BKYoCQJ3ndMcbbtH","2252seNhipfTmjEBQ","ibLPPAndxdcRpxcwH"]}