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  2025 (1)
Macrocyclic peptides as a new class of targeted protein degraders. Jing, X.; Mackay, J., P.; and Passioura, T. RSC Chem Biol, 6(3): 326-337. 2025.
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  2024 (11)
Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Bedding, M., J.; Franck, C.; Johansen-Leete, J.; Aggarwal, A.; Maxwell, J., W., C.; Patel, K.; Hawkins, P.; Low, J., K., K.; Siddiquee, R.; Moghaddas Sani, H.; Ford, D., J.; Turville, S., G.; Mackay, J., P.; Passioura, T.; Christie, M.; and Payne, R., J. ACS Chemical Biology, 19: 141-152. 2024.
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Tyrosine Sulfation Modulates the Binding Activity of Chemokine-Targeting Nanobodies. Dilly, J., J.; Franck, C.; Bhusal, R.; Morgan, A.; Bedding, M., J.; Low, J., K., K.; Mackay, J., P.; Stone, M., J.; and Payne, R., J. ACS Chemical Biology, 19(7): 1426-1432. 2024.
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Molecular dissection of cobra venom highlights heparinoids as an effective snakebite antidote. Du, T., Y.; Hall, S., R.; Chung, F.; Kurdyukov, S.; Crittenden, E.; Patel, K.; Dawson, C., A.; Westhorpe, A., P.; Bartlett, K., E.; Rasmussen, S., A.; Moreno, C.; Denes, C., E.; Albulescu, L.; Marriott, A., E.; Mackay, J., P.; Wilkinson, M., C.; Gutierrez, J., M.; Casewell, N., R.; and Neely, G., G. Science Transl. Med., 16: eadk4802. 2024.
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Dynamin 1xA interacts with Endophilin A1 via its spliced long C-terminus for ultrafast endocytosis. Imoto, Y.; Xue, J.; Luo, L.; Raychaudhuri, S.; Itoh, K.; Ma, Y.; Craft, G., E.; Kwan, A., H.; Ogunmowo, T., H.; Ho, A.; Mackay, J., P.; Ha, T.; Watanabe, S.; and Robinson, P., J. EMBO Journal, 43(16): 3327-3357. 2024.
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Expressed protein ligation in flow. Kambanis, L.; Ayoub, A.; Bedding, M., J.; Egelund, P., H., G.; Maxwell, J., W., C.; Franck, C.; Lambrechts, L.; Hawkins, P., M., E.; Chisholm, T., S.; Mackay, J., P.; Sierecki, E.; Gambin, Y.; Kulkarni, S., S.; and Payne, R., J. Journal of the American Chemical Society, 146(31): 22027-22035. 2024.
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Structural Biology in cellulo: Minding the gap between conceptualization and realization. Kyrilis, F.; Low, J., K., K.; Mackay, J., P.; and Panagiotis, K. Current Opinion in Structural Biology, 87: 102843. 2024.
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The transcriptional co-repressor Runx1t1 is essential for N-Myc-driven neuroblastoma tumorigenesis. Murray, J., E.; Valli, E.; Milazzo, G.; Mayoh, C.; Gifford, A., J.; Fletcher, J., I.; Xue, C.; Jayatilleke, N.; Salehzadeh, F.; Gamble, L.; Rouaen, J.; Carter, D.; Forgham, H.; Sekyere, E., O.; Keating, J.; Eden, G.; Allan, S.; Alfred, S.; Kusuma, F.; Clark, A.; Webber, H.; Russell, A., J.; de Weck, A.; Kile, B., T.; Santulli, M.; De Rosa, P.; Fleuren, E., D., G.; Gao, W.; Wilkinson-White, L.; Low, J., K., K.; Mackay, J., P.; Marshall, G., M.; Hilton, D., J.; Giorgi, F.; Koster, J.; Perini, G.; Haber, M.; and Norris, M., D. Nature Commun, 15(1): 5585. 2024.
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Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression. Rajendiran, V.; Devaraju, N.; Haddad, M.; Ravi, N., S.; Panigrahi, L.; Paul, J.; Gopalakrishnan, C.; Wyman, S.; Ariudainambi, K.; Mahalingam, G.; Perisasami, Y.; Prasad, K.; George, A.; Sukimaran, D.; Gopinathan, S.; Pai, A., A.; Nakamura, Y.; Balsubramanian, P.; Ramalingam, R.; Thangavel, S.; Velayudhan, S., R.; Corn, J., E.; Mackay, J., P.; Marepally, S.; Srivastava, A.; Crossley, M.; and Mohankumar, K., M. Molecular Therapy, 32: 663-677. 2024.
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ZNF512B binds RBBP4 via a variant NuRD interaction motif and aggregates chromatin in a NuRD complex-independent manner. Wunderlich, T.; Deshpande, C.; Paasche, L.; Friedrich, T.; Diegmuller, F.; Haddad, E.; Kreienbaum, C.; Naseer, H.; Stebel, S.; Daus, N.; Leers, J.; Lan, J.; Trinh, V.; Vazquez, O.; Butter, F.; Bartkuhn, M.; Mackay, J., P.; and Hake, S. Nucl Acids Res, 52(21): 12831-12849. 2024.
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How does CHD4 slide nucleosomes?. Reid, X., J.; Zhong, Y.; and Mackay, J., P. Biochemical Society Transactions, 52(5): 1995-2008. 2024.
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ZNF827 is a single-stranded DNA binding protein that interacts with TOPBP1 to regulate the ATR-CHK1 DNA damage response pathway. Yang, S., F.; Nelson, C., B.; Wells, J., K.; Fernando, M.; Lu, R.; Allen, R., A.; Malloy, L.; Lamm, N.; Murphy, V., J.; Mackay, J., P.; Deans, A., J.; Cesare, A., J.; Sobinoff, A., P.; and Pickett, H., A. Nature Commun, 15: 2210. 2024.
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  2023 (10)
Rapid Elaboration of Fragments into Leads applied to BRD3-extra terminal domain. Adams, L., A.; Wilkinson-White, L., E.; Gunzburg, M., J.; Headey, S., J.; Mohanty, B.; Scanlon, M., J.; Capuano, B.; Mackay, J., P.; and Doak, B., C. Journal of Medicinal Chemistry, 66(8): 5859-5872. 2023.
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Cross-linking mass spectrometry discovers, evaluates, and validates the experimental and predicted structural proteome. Bartolec, T., K.; Vazquez-Campos, X.; Norman, A.; Luong, C.; Johnson, M.; Payne, R., J.; Wilkins, M., R.; Mackay, J., P.; and Low, J., K., K. Proceedings of the National Academy of Sciences, USA, 120(17): e2219418120. 2023.
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Discovery and characterization of cyclic peptides selective for the C-terminal bromodomains of BET family proteins. Franck, C.; Patel, K.; Walport, L., J.; Christie, M.; Norman, A.; Passioura, T.; Suga, H.; Payne, R., J.; and Mackay, J., P. Structure, 31(8): 912-923. 2023.
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The H2A.Z.1/PWWP2A/NuRD-associated protein HMG20A controls early head and heart developmental transcription programs. Herchenrother, A.; Gossen, S.; Friedrich, T.; Reim, A.; Daus, N.; Diegmuller, F.; Sgellmacher, I.; Szymkowiak, L.; Nist, A.; Stiewe, T.; Borggrefe, T.; Mann, M.; Mackay, J., P.; Bartkuhn, M.; Borchers, C., H.; Lan, J.; and Hake, S. Nature Commun, 14: 472. 2023.
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DUF2285 is a novel helix-turn-helix domain variant that orchestrates both activation and antiactivation of conjugative element transfer in proteobacteria. Jowsey, W., J.; Morris, C., R., P.; Hall, D.; Sullivan, J., T.; Fagerlund, R.; Eto, K., Y.; Solomon, P., D.; Mackay, J., P.; Bond, C., S.; Ramsay, J., P.; and Ronson, C., W. Nucl Acids Res, 51(13): 6841-6856. 2023.
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Pathogenic human variant that dislocates GATA2 zinc fingers establishes hematopoiesis-disrupting gene expression and signaling networks. Jung, M., M.; Shen, S.; Botten, G.; Olender, T.; Katsumura, K., R.; Johnson, K., D.; Soukup, A., A.; Liu, P.; Zhang, Q.; Jensfold, Z.; Lewis, P., W.; Beagrie, R., A.; Low, J., K., K.; Yang, L.; Mackay, J., P.; Godley, J., A.; Brand, M.; Xu, J.; Keles, S.; and Bresnick, E., H. Journal of Clinical Investigation, 133(7): e162685. 2023.
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Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs. Loo, L.; Waller, M.; Moreno, C.; Cole, A.; Ospina Stella, A.; Pop, O.; Jochum, A.; Ali, O., H.; Denes, C.; Hamoudi, Z.; Chung, F.; Aggarwal, A.; Low, J., K., K.; Patel, K.; Siddiquee, R.; Kang, T.; Mathivanan, S.; Mackay, J., P.; Jochum, W.; Flatz, L.; Hesselson, D.; Turville, S., G.; and Neely, G., G. PLoS Biology, 21(2): e3001967. 2023.
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mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome. Low, J., K., K.; Patel, K.; Jones, N.; Solomon, P.; Norman, A.; Maxwell, J., W., C.; Pachl, P.; Matthews, J., M.; Payne, R., J.; Passioura, T.; Suga, H.; Walport, L., J.; and Mackay, J., P. Journal of Biological Chemistry, 299(12): 105482-105495. 2023.
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A NuRD for all seasons. Reid, X., J.; Low, J., K., K.; and Mackay, J., P. Trends Biochem Sci, 48(1): 11-25. 2023.
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De novo variants in GATAD2A in individuals with developmental disorders. Werren, E., A.; Guxholli, A.; Jones, N.; Wagner, M.; Hannibal, I.; Granadillo, J., L.; Tyndall, A., V.; Moccia, A.; Kuehl, R.; Levandoski, K., M.; Day-Salvatore, D., L.; Wheeler, M.; Genomics, U., o., W., C., f., M.; Chong, J., X.; Bamshad, M., J.; Innes, M.; Pierson, T., M.; Mackay, J., P.; Bielas, S., L.; and Martin, D., M. Human Genet Genom Adv, 4(3): 100198. 2023.
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  2022 (8)
Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine. Dowman, L.; Kulkarni, S.; Alegre-Requena, J.; Giltrap, A.; Norman, A.; Sharma, A.; Gallegos, L.; Mackay, A.; Welegedara, A.; Watson, E.; Paton, R.; and Payne, R. Nature Communications, 13(1). 2022.
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The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families. Zhong, Y.; Moghaddas Sani, H.; Paudel, B.; Low, J.; Silva, A.; Mueller, S.; Deshpande, C.; Panjikar, S.; Reid, X.; Bedward, M.; van Oijen, A.; and Mackay, J. Nature Communications, 13(1). 2022.
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Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice. Ashhurst, A.; Johansen, M.; Maxwell, J.; Stockdale, S.; Ashley, C.; Aggarwal, A.; Siddiquee, R.; Miemczyk, S.; Nguyen, D.; Mackay, J.; Payne, R.; and Britton, W. Nature Communications, 13(1). 2022.
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RNA inhibits dMi-2/CHD4 chromatin binding and nucleosome remodeling. Ullah, I.; Thölken, C.; Zhong, Y.; John, M.; Rossbach, O.; Lenz, J.; Gößringer, M.; Nist, A.; Albert, L.; Stiewe, T.; Mackay, J.; and Brehm, A. Cell Reports, 39(9). 2022.
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Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability. Hodson, C.; Low, J.; van Twest, S.; Jones, S.; Swuec, P.; Murphy, V.; Tsukada, K.; Fawkes, M.; Bythell-Douglas, R.; Davies, A.; Costa, A.; and Deans, A. Proceedings of the National Academy of Sciences of the United States of America, 119(6). 2022.
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Molecular architecture of nucleosome remodeling and deacetylase sub-complexes by integrative structure determination. Arvindekar, S.; Jackman, M.; Low, J.; Landsberg, M.; Mackay, J.; and Viswanath, S. Protein Science, 31(9). 2022.
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TNP Analogues Inhibit the Virulence Promoting IP3-4 Kinase Arg1 in the Fungal Pathogen Cryptococcus neoformans. Desmarini, D.; Truong, D.; Wilkinson-White, L.; Desphande, C.; Torrado, M.; Mackay, J.; Matthews, J.; Sorrell, T.; Lev, S.; Thompson, P.; Thompson, P.; and Djordjevic, J. Biomolecules, 12(10). 2022.
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Unique protein interaction networks define the chromatin remodelling module of the NuRD complex. Sharifi Tabar, M.; Giardina, C.; Feng, Y.; Francis, H.; Moghaddas Sani, H.; Low, J.; Mackay, J.; Bailey, C.; and Rasko, J. FEBS Journal, 289(1): 199-214. 2022.
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  2021 (7)
BET-Family Bromodomains Can Recognize Diacetylated Sequences from Transcription Factors Using a Conserved Mechanism. Patel, K.; Solomon, P.; Walshe, J.; Ford, D.; Wilkinson-White, L.; Payne, R.; Low, J.; and Mackay, J. Biochemistry, 60(9): 648-662. 2021.
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The characterization of protein interactions-what, how and how much?. Walport, L.; Low, J.; Matthews, J.; and MacKay, J. Chemical Society Reviews, 50(22): 12292-12307. 2021.
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The bromodomains of BET family proteins can recognize diacetylated histone H2A.Z. Patel, K.; Solomon, P.; Walshe, J.; Low, J.; and Mackay, J. Protein Science, 30(2): 464-476. 2021.
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Late-stage modification of peptides and proteins at cysteine with diaryliodonium salts. Byrne, S.; Bedding, M.; Corcilius, L.; Ford, D.; Zhong, Y.; Franck, C.; Larance, M.; Mackay, J.; and Payne, R. Chemical Science, 12(42): 14159-14166. 2021.
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A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilising immunity against SARS-CoV-2 infection. Counoupas, C.; Johansen, M.; Stella, A.; Nguyen, D.; Ferguson, A.; Aggarwal, A.; Bhattacharyya, N.; Grey, A.; Hutchings, O.; Patel, K.; Hansbro, P.; and Triccas, J. npj Vaccines, 6(1). 2021.
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Purification of an insect juvenile hormone receptor complex enables insights into its post-translational phosphorylation. Jindra, M.; McKinstry, W.; Nebl, T.; Bittova, L.; Ren, B.; Shaw, J.; Phan, T.; Lu, L.; Low, J.; Mackay, J.; Lovrecz, G.; and Hill, R. Journal of Biological Chemistry, 297(6). 2021.
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Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display. Norman, A.; Franck, C.; Christie, M.; Hawkins, P.; Patel, K.; Ashhurst, A.; Aggarwal, A.; Low, J.; Siddiquee, R.; Ashley, C.; Passioura, T.; and Payne, R. ACS Central Science, 7(6): 1001-1008. 2021.
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  2020 (15)
GATAD2B-associated neurodevelopmental disorder (GAND): clinical and molecular insights into a NuRD-related disorder. Shieh, C.; Jones, N.; Vanle, B.; Au, M.; Huang, A., Y.; Silva, A., P., G.; Lee, H.; Douine, E., D.; Otero, M., G.; Choi, A.; Grand, K.; Taff, I., P.; Delgado, M., R.; Hajianpour, M., J.; Seeley, A.; Rohena, L.; Vernon, H.; Gripp, K., W.; Vergano, S., A.; Mahida, S.; Naidu, S.; Sousa, A., B.; Wain, K., E.; Challman, T., D.; Beek, G.; Basel, D.; Ranells, J.; Smith, R.; Yusupov, R.; Freckmann, M.; Ohden, L.; Davis-Keppen, L.; Chitayat, D.; Dowling, J., J.; Finkel, R.; Dauber, A.; Spillmann, R.; Pena, L., D., M.; Metcalfe, K.; Splitt, M.; Lachlan, K.; McKee, S., A.; Hurst, J.; Fitzpatrick, D., R.; Morton, J., E., V.; Cox, H.; Venkateswaran, S.; Young, J., I.; Marsh, E., D.; Nelson, S., F.; Martinez, J., A.; Graham, J., M.; Kini, U.; Mackay, J., P.; and Pierson, T., M. Genetics in Medicine, 22(5): 878-888. 5 2020.
GATAD2B-associated neurodevelopmental disorder (GAND): clinical and molecular insights into a NuRD-related disorder [link]Website   doi   link   bibtex   abstract   1 download  
Peppy: A virtual reality environment for exploring the principles of polypeptide structure. Doak, D., G.; Denyer, G., S.; Gerrard, J., A.; Mackay, J., P.; and Allison, J., R. Protein Science, 29(1): 157-168. 1 2020.
Peppy: A virtual reality environment for exploring the principles of polypeptide structure [link]Website   doi   link   bibtex   abstract   1 download  
Cyclic peptides can engage a single binding pocket through highly divergent modes. Patel, K.; Walport, L.; Walshe, J.; Solomon, P.; Low, J.; Tran, D.; Mouradian, K.; Silva, A.; Wilkinson-White, L.; Norman, A.; Franck, C.; Matthews, J.; Mitchell Guss, J.; Payne, R.; Passioura, T.; Suga, H.; and Mackay, J. Proceedings of the National Academy of Sciences of the United States of America, 117(43). 2020.
doi   link   bibtex   abstract   1 download  
GATAD2B-associated neurodevelopmental disorder (GAND): clinical and molecular insights into a NuRD-related disorder. Shieh, C.; Jones, N.; Vanle, B.; Au, M.; Huang, A.; Silva, A.; Lee, H.; Douine, E.; Otero, M.; Choi, A.; Mackay, J.; and Pierson, T. Genetics in Medicine, 22(5): 878-888. 2020.
doi   link   bibtex   abstract   1 download  
Correction: Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system.(Applied Optics(2020)295(1898–1914)Doi: 10.1074/jbc.RA119.010679). Werner, M.; Wang, H.; Hamagami, N.; Hsu, S.; Yano, J.; Stonestrom, A.; Behera, V.; Zhong, Y.; MacKay, J.; and Blobel, G. Journal of Biological Chemistry, 295(18): 6251. 2020.
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Cyclic peptides can engage a single binding pocket through highly divergent modes. Patel, K.; Walport, L.; Walshe, J.; Solomon, P.; Low, J.; Tran, D.; Mouradian, K.; Silva, A.; Wilkinson-White, L.; Norman, A.; Suga, H.; and Mackay, J. Proceedings of the National Academy of Sciences of the United States of America, 117(43): 26728-26738. 2020.
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Semisynthesis of an evasin from tick saliva reveals a critical role of tyrosine sulfation for chemokine binding and inhibition. Franck, C.; Foster, S.; Johansen-Leete, J.; Chowdhury, S.; Cielesh, M.; Bhusal, R.; Mackay, J.; Larance, M.; Stone, M.; and Payne, R. Proceedings of the National Academy of Sciences of the United States of America, 117(23): 12657-12664. 2020.
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A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2. Xi, C.; Di Fazio, A.; Nadvi, N.; Patel, K.; Xiang, M.; Zhang, H.; Deshpande, C.; Low, J.; Wang, X.; Chen, Y.; Church, W.; and Gorrell, M. Molecules, 25(22). 2020.
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CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation. Zhong, Y.; Paudel, B.; Ryan, D.; Low, J.; Franck, C.; Patel, K.; Bedward, M.; Torrado, M.; Payne, R.; van Oijen, A.; van Oijen, A.; and Mackay, J. Nature Communications, 11(1). 2020.
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A heme-binding protein produced by Haemophilus haemolyticus inhibits non-typeable Haemophilus influenzae. Latham, R.; Torrado, M.; Atto, B.; Walshe, J.; Wilson, R.; Guss, J.; Mackay, J.; Tristram, S.; and Gell, D. Molecular Microbiology, 113(2): 381-398. 2020.
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Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system. Werner, M.; Wang, H.; Hamagami, N.; Hsu, S.; Yano, J.; Stonestrom, A.; Behera, V.; Zong, Y.; Mackay, J.; and Blobel, G. Journal of Biological Chemistry, 295(7): 1898-1914. 2020.
doi   link   bibtex   abstract   1 download  
Thermostable small-molecule inhibitor of angiogenesis and vascular permeability that suppresses a pERK-FosB/ΔFosB-VCAM-1 axis. Li, Y.; Alhendi, A.; Yeh, M.; Elahy, M.; Santiago, F.; Deshpande, N.; Wu, B.; Chan, E.; Inam, S.; Prado-Lourenco, L.; Marcuccio, S.; and Khachigian, L. Science Advances, 6(31). 2020.
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The Nucleosome Remodeling and Deacetylase Complex Has an Asymmetric, Dynamic, and Modular Architecture. Low, J.; Silva, A.; Sharifi Tabar, M.; Torrado, M.; Webb, S.; Parker, B.; Sana, M.; Smits, C.; Schmidberger, J.; Brillault, L.; Landsberg, M.; and Mackay, J. Cell Reports, 33(9). 2020.
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Peppy: A virtual reality environment for exploring the principles of polypeptide structure. Doak, D.; Denyer, G.; Gerrard, J.; Mackay, J.; and Allison, J. Protein Science, 29(1): 157-168. 2020.
doi   link   bibtex   abstract   1 download  
Correction: GATAD2B-associated neurodevelopmental disorder (GAND): clinical and molecular insights into a NuRD-related disorder (Genetics in Medicine, (2020), 10.1038/s41436-019-0747-z). Shieh, C.; Jones, N.; Vanle, B.; Au, M.; Huang, A.; Silva, A.; Lee, H.; Douine, E.; Otero, M.; Choi, A.; Mackay, J.; and Pierson, T. Genetics in Medicine, 22(4): 822. 2020.
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  2019 (6)
The NuRD complex and macrocephaly associated neurodevelopmental disorders. Pierson, T., M.; Otero, M., G.; Grand, K.; Choi, A.; Graham, J., M.; Young, J., I.; and Mackay, J., P. American Journal of Medical Genetics Part C: Seminars in Medical Genetics, 181(4): 548-556. 12 2019.
The NuRD complex and macrocephaly associated neurodevelopmental disorders [link]Website   doi   link   bibtex   abstract  
The uncharacterized bacterial protein YejG has the same architecture as domain III of elongation factor G. Mohanty, B.; Hanson‐Manful, P.; Finn, T., J.; Chambers, C., R.; McKellar, J., L., O.; Macindoe, I.; Helder, S.; Setiyaputra, S.; Zhong, Y.; Mackay, J., P.; and Patrick, W., M. Proteins: Structure, Function, and Bioinformatics, 87(8): 699-705. 8 2019.
The uncharacterized bacterial protein YejG has the same architecture as domain III of elongation factor G [link]Website   doi   link   bibtex   abstract  
The uncharacterized bacterial protein YejG has the same architecture as domain III of elongation factor G. Mohanty, B.; Hanson-Manful, P.; Finn, T.; Chambers, C.; McKellar, J.; Macindoe, I.; Helder, S.; Setiyaputra, S.; Zhong, Y.; Mackay, J.; Mackay, J.; and Patrick, W. Proteins: Structure, Function and Bioinformatics, 87(8): 699-705. 2019.
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The stoichiometry and interactome of the Nucleosome Remodeling and Deacetylase (NuRD) complex are conserved across multiple cell lines. Sharifi Tabar, M.; Mackay, J.; and Low, J. FEBS Journal, 286(11): 2043-2061. 2019.
doi   link   bibtex   abstract   3 downloads  
Exploring the suitability of RanBP2-type Zinc Fingers for RNA-binding protein design. De Franco, S.; Vandenameele, J.; Brans, A.; Verlaine, O.; Bendak, K.; Damblon, C.; Matagne, A.; Segal, D.; Galleni, M.; Mackay, J.; Mackay, J.; and Vandevenne, M. Scientific Reports, 9(1). 2019.
doi   link   bibtex   abstract   6 downloads  
The NuRD complex and macrocephaly associated neurodevelopmental disorders. Pierson, T.; Otero, M.; Grand, K.; Choi, A.; Graham, J.; Young, J.; and Mackay, J. American Journal of Medical Genetics, Part C: Seminars in Medical Genetics, 181(4): 548-556. 2019.
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  2018 (11)
Crystal structure of the Melampsora lini effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein P. Zhang, X.; Farah, N.; Rolston, L.; Ericsson, D., J.; Catanzariti, A.; Bernoux, M.; Ve, T.; Bendak, K.; Chen, C.; Mackay, J., P.; Lawrence, G., J.; Hardham, A.; Ellis, J., G.; Williams, S., J.; Dodds, P., N.; Jones, D., A.; and Kobe, B. Molecular Plant Pathology, 19(5): 1196-1209. 5 2018.
Crystal structure of the Melampsora lini effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein P [link]Website   doi   link   bibtex   abstract  
Expression, purification and DNA-binding properties of zinc finger domains of DOF proteins from Arabidopsis thaliana. Moghaddas Sani, H.; Hamzeh-Mivehroud, M.; Silva, A., P.; Walshe, J., L.; Mohammadi, S., A.; Rahbar-Shahrouziasl, M.; Abbasi, M.; Jamshidi, O.; Low, J., K.; Dastmalchi, S.; and Mackay, J., P. BioImpacts, 8(3): 167-176. 1 2018.
Expression, purification and DNA-binding properties of zinc finger domains of DOF proteins from Arabidopsis thaliana [link]Website   doi   link   bibtex   abstract  
Receptor homodimerization plays a critical role in a novel dominant negative P2RY12 variant identified in a family with severe bleeding. Mundell, S., J.; Rabbolini, D.; Gabrielli, S.; Chen, Q.; Aungraheeta, R.; Hutchinson, J., L.; Kilo, T.; Mackay, J.; Ward, C., M.; Stevenson, W.; and Morel-Kopp, M. Journal of Thrombosis and Haemostasis, 16(1): 44-53. 1 2018.
Receptor homodimerization plays a critical role in a novel dominant negative P2RY12 variant identified in a family with severe bleeding [link]Website   doi   link   bibtex   abstract  
NMR Spectroscopy in the Analysis of Protein-Protein Interactions. Gell, D., A.; Kwan, A., H.; and Mackay, J., P. Modern Magnetic Resonance, pages 2099-2132. Springer International Publishing, 2018.
Modern Magnetic Resonance [link]Website   doi   link   bibtex   abstract  
Receptor homodimerization plays a critical role in a novel dominant negative P2RY12 variant identified in a family with severe bleeding. Mundell, S.; Rabbolini, D.; Gabrielli, S.; Chen, Q.; Aungraheeta, R.; Hutchinson, J.; Kilo, T.; Mackay, J.; Ward, C.; Stevenson, W.; Stevenson, W.; and Morel-Kopp, M. Journal of Thrombosis and Haemostasis, 16(1): 44-53. 2018.
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Expression, purification and DNA-binding properties of zinc finger domains of DOF proteins from Arabidopsis thaliana. Sani, H.; Hamzeh-Mivehroud, M.; Silva, A.; Walshe, J.; Abolghasem Mohammadi, S.; Rahbar-Shahrouziasl, M.; Abbasi, M.; Jamshidi, O.; Low, J.; Dastmalchi, S.; Dastmalchi, S.; and Mackay, J. BioImpacts, 8(3): 167-176. 2018.
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NMR spectroscopy in the analysis of protein-protein interactions. Gell, D.; Kwan, A.; and Mackay, J. 2018.
doi   link   bibtex   abstract  
The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators. Wai, D.; Szyszka, T.; Campbell, A.; Kwong, C.; Lorna, E.; Silva, A.; Low, J.; Kwan, A.; Gamsjaeger, R.; Chalmers, J.; Blobel, G.; and Mackay, J. Journal of Biological Chemistry, 293(19): 7160-7175. 2018.
doi   link   bibtex   abstract  
A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence. Lu, B.; Klingbeil, O.; Tarumoto, Y.; Somerville, T.; Huang, Y.; Wei, Y.; Wai, D.; Low, J.; Milazzo, J.; Wu, X.; Shi, J.; and Vakoc, C. Cancer Cell, 34(6): 970-981.e8. 2018.
doi   link   bibtex   abstract  
Crystal structure of the Melampsora lini effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein P. Zhang, X.; Farah, N.; Rolston, L.; Ericsson, D.; Catanzariti, A.; Bernoux, M.; Ve, T.; Bendak, K.; Chen, C.; Mackay, J.; Jones, D.; and Kobe, B. Molecular Plant Pathology, 19(5): 1196-1209. 2018.
doi   link   bibtex   abstract  
  2017 (8)
Refinement of the subunit interaction network within the nucleosome remodelling and deacetylase (NuRD) complex. Torrado, M.; Low, J., K., K.; Silva, A., P., G.; Schmidberger, J., W.; Sana, M.; Sharifi Tabar, M.; Isilak, M., E.; Winning, C., S.; Kwong, C.; Bedward, M., J.; Sperlazza, M., J.; Williams, D., C.; Shepherd, N., E.; and Mackay, J., P. The FEBS Journal, 284(24): 4216-4232. 12 2017.
Refinement of the subunit interaction network within the nucleosome remodelling and deacetylase (NuRD) complex [link]Website   doi   link   bibtex   abstract  
Arabinosylation Modulates the Growth-Regulating Activity of the Peptide Hormone CLE40a from Soybean. Corcilius, L.; Hastwell, A., H.; Zhang, M.; Williams, J.; Mackay, J., P.; Gresshoff, P., M.; Ferguson, B., J.; and Payne, R., J. Cell Chemical Biology, 24(11): 1347-1355.e7. 11 2017.
Arabinosylation Modulates the Growth-Regulating Activity of the Peptide Hormone CLE40a from Soybean [link]Website   doi   link   bibtex   abstract  
Refinement of the subunit interaction network within the nucleosome remodelling and deacetylase (NuRD) complex. Torrado, M.; Low, J.; Silva, A.; Schmidberger, J.; Sana, M.; Sharifi Tabar, M.; Isilak, M.; Winning, C.; Kwong, C.; Bedward, M.; Shepherd, N.; and Mackay, J. FEBS Journal, 284(24): 4216-4232. 2017.
doi   link   bibtex   abstract  
Arabinosylation Modulates the Growth-Regulating Activity of the Peptide Hormone CLE40a from Soybean. Corcilius, L.; Hastwell, A.; Zhang, M.; Williams, J.; Mackay, J.; Gresshoff, P.; Ferguson, B.; and Payne, R. Cell Chemical Biology, 24(11): 1347-1355.e7. 2017.
doi   link   bibtex   abstract  
DCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression. O'Geen, H.; Ren, C.; Nicolet, C.; Perez, A.; Halmai, J.; Le, V.; MacKay, J.; Farnham, P.; and Segal, D. Nucleic Acids Research, 45(17): 9901-9916. 2017.
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Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability. Gillinder, K.; Ilsley, M.; Nébor, D.; Sachidanandam, R.; Lajoie, M.; Magor, G.; Tallack, M.; Bailey, T.; Landsberg, M.; Mackay, J.; Bieker, J.; and Perkins, A. Nucleic Acids Research, 45(3): 1130-1143. 2017.
doi   link   bibtex   abstract   2 downloads  
IP3-4 kinase Arg1 regulates cell wall homeostasis and surface architecture to promote clearance of Cryptococcus neoformans infection in a mouse model. Li, C.; Lev, S.; Desmarini, D.; Kaufman-Francis, K.; Saiardi, A.; Silva, A.; Mackay, J.; Thompson, P.; Sorrell, T.; and Djordjevic, J. Virulence, 8(8): 1833-1848. 2017.
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Whaddaya Know: A Guide to Uncertainty and Subjectivity in Structural Biology. Mackay, J.; Landsberg, M.; Whitten, A.; and Bond, C. Trends in Biochemical Sciences, 42(2): 155-167. 2017.
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  2016 (13)
The Chromatin Remodelling Protein CHD1 Contains a Previously Unrecognised C-Terminal Helical Domain. Mohanty, B.; Helder, S.; Silva, A., P.; Mackay, J., P.; and Ryan, D., P. Journal of Molecular Biology, 428(21): 4298-4314. 10 2016.
The Chromatin Remodelling Protein CHD1 Contains a Previously Unrecognised C-Terminal Helical Domain [link]Website   doi   link   bibtex   abstract  
The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein. Blythe, A., J.; Yazar-Klosinski, B.; Webster, M., W.; Chen, E.; Vandevenne, M.; Bendak, K.; Mackay, J., P.; Hartzog, G., A.; and Vrielink, A. Protein Science, 25(9): 1710-1721. 9 2016.
The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein [link]Website   doi   link   bibtex   abstract  
The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7. Schmidberger, J., W.; Sharifi Tabar, M.; Torrado, M.; Silva, A., P., G.; Landsberg, M., J.; Brillault, L.; AlQarni, S.; Zeng, Y., C.; Parker, B., L.; Low, J., K., K.; and Mackay, J., P. Protein Science, 25(8): 1472-1482. 8 2016.
The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7 [link]Website   doi   link   bibtex   abstract  
The Chromatin Remodelling Protein CHD1 Contains a Previously Unrecognised C-Terminal Helical Domain. Mohanty, B.; Helder, S.; Silva, A.; Mackay, J.; and Ryan, D. Journal of Molecular Biology, 428(21): 4298-4314. 2016.
doi   link   bibtex   abstract  
Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice. Ittner, A.; Chua, S.; Bertz, J.; Volkerling, A.; Van Der Hoven, J.; Gladbach, A.; Przybyla, M.; Bi, M.; Van Hummel, A.; Stevens, C.; Ke, Y.; and Ittner, L. Science, 354(6314): 904-908. 2016.
doi   link   bibtex   abstract  
The zinc fingers of YY1 bind single-stranded RNA with low sequence specificity. Wai, D.; Shihab, M.; Low, J.; and Mackay, J. Nucleic Acids Research, 44(19): 9153-9165. 2016.
doi   link   bibtex   abstract  
Determinants of affinity and specificity in RNA-binding proteins. Helder, S.; Blythe, A.; Bond, C.; and Mackay, J. Current Opinion in Structural Biology, 38: 83-91. 2016.
doi   link   bibtex   abstract  
The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7. Schmidberger, J.; Sharifi Tabar, M.; Torrado, M.; Silva, A.; Landsberg, M.; Brillault, L.; AlQarni, S.; Zeng, Y.; Parker, B.; Low, J.; Low, J.; and Mackay, J. Protein Science,1472-1482. 2016.
doi   link   bibtex   abstract  
The N-terminal region of chromodomain helicase DNA-binding protein 4 (CHD4) is essential for activity and contains a high mobility group (HMG) box-like-domain that can bind poly(ADP-ribose). Silva, A.; Ryan, D.; Galanty, Y.; Low, J.; Vandevenne, M.; Jackson, S.; and Mackay, J. Journal of Biological Chemistry, 291(2): 924-938. 2016.
doi   link   bibtex   abstract  
CHD4 is a peripheral component of the nucleosome remodeling and deacetylase complex. Low, J.; Webb, S.; Silva, A.; Saathoff, H.; Ryan, D.; Torrado, M.; Brofelth, M.; Parker, B.; Shepherd, N.; and Mackay, J. Journal of Biological Chemistry, 291(30): 15853-15866. 2016.
doi   link   bibtex   abstract  
The binding of syndapin SH3 domain to Dynamin proline-rich domain involves short and long distance elements. Luo, L.; Xue, J.; Kwan, A.; Gamsjaeger, R.; Wielens, J.; Von Kleist, L.; Cubeddu, L.; Guo, Z.; Stow, J.; Parker, M.; Mackay, J.; and Robinson, P. Journal of Biological Chemistry, 291(18): 9411-9424. 2016.
doi   link   bibtex   abstract  
1H, 13C and 15N resonance assignments of a C-terminal domain of human CHD1. Mohanty, B.; Silva, A.; Mackay, J.; and Ryan, D. Biomolecular NMR Assignments, 10(1): 31-34. 2016.
doi   link   bibtex   abstract  
The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein. Blythe, A.; Yazar-Klosinski, B.; Webster, M.; Chen, E.; Vandevenne, M.; Bendak, K.; Mackay, J.; Hartzog, G.; and Vrielink, A. Protein Science,1710-1721. 2016.
doi   link   bibtex   abstract  
  2015 (4)
A peptide affinity reagent for isolating an intact and catalytically active multi-protein complex from mammalian cells. Saathoff, H.; Brofelth, M.; Trinh, A.; Parker, B., L.; Ryan, D., P.; Low, J., K.; Webb, S., R.; Silva, A., P.; Mackay, J., P.; and Shepherd, N., E. Bioorganic & Medicinal Chemistry, 23(5): 960-965. 3 2015.
A peptide affinity reagent for isolating an intact and catalytically active multi-protein complex from mammalian cells [link]Website   doi   link   bibtex   abstract  
Paris-Trousseau thrombocytopenia is phenocopied by the autosomal recessive inheritance of a DNA-binding domain mutation in FLI1. Stevenson, W.; Rabbolini, D.; Beutler, L.; Chen, Q.; Gabrielli, S.; Mackay, J.; Brighton, T.; Ward, C.; and Morel-Kopp, M. Blood, 126(17): 2027-2030. 2015.
doi   link   bibtex   abstract  
Site directed nitroxide spin labeling of oligonucleotides for NMR and EPR studies. Shepherd, N.; Gamsjaeger, R.; Vandevenne, M.; Cubeddu, L.; and Mackay, J. Tetrahedron, 71(5): 813-819. 2015.
doi   link   bibtex   abstract  
A peptide affinity reagent for isolating an intact and catalytically active multi-protein complex from mammalian cells. Saathoff, H.; Brofelth, M.; Trinh, A.; Parker, B.; Ryan, D.; Low, J.; Webb, S.; Silva, A.; Mackay, J.; and Shepherd, N. Bioorganic and Medicinal Chemistry, 23(5): 960-965. 2015.
doi   link   bibtex   abstract  
  2014 (15)
1H, 13C and 15N resonance assignments of an N-terminal domain of CHD4. Silva, A., P., G.; Kwan, A., H.; and Mackay, J., P. Biomolecular NMR Assignments, 8(1): 137-139. 4 2014.
1H, 13C and 15N resonance assignments of an N-terminal domain of CHD4 [link]Website   doi   link   bibtex   abstract  
Engineering Specificity Changes on a RanBP2 Zinc Finger that Binds Single-Stranded RNA. Vandevenne, M.; O'Connell, M., R.; Helder, S.; Shepherd, N., E.; Matthews, J., M.; Kwan, A., H.; Segal, D., J.; and Mackay, J., P. Angewandte Chemie International Edition, 53(30): 7848-7852. 7 2014.
Engineering Specificity Changes on a RanBP2 Zinc Finger that Binds Single-Stranded RNA [link]Website   doi   link   bibtex   abstract  
Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1. Joseph, S.; Kwan, A., H., Y.; Mackay, J., P.; Cubeddu, L.; and Matthews, J., M. Biomolecular NMR Assignments, 8(1): 141-144. 4 2014.
Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1 [link]Website   doi   link   bibtex   abstract  
The identification and structure of an N-terminal PR domain show that FOG1 is a member of the PRDM family of proteins. Clifton, M.; Westman, B.; Thong, S.; O'Connell, M.; Webster, M.; Shepherd, N.; Quinlan, K.; Crossley, M.; Blobel, G.; and Mackay, J. PLoS ONE, 9(8). 2014.
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Ca2+-induced PRE-NMR changes in the troponin complex reveal the possessive nature of the cardiac isoform for its regulatory switch. Cordina, N.; Liew, C.; Potluri, P.; Curmi, P.; Fajer, P.; Logan, T.; Mackay, J.; and Brown, L. PLoS ONE, 9(11). 2014.
doi   link   bibtex   abstract  
Engineering specificity changes on a RanBP2 zinc finger that binds single-stranded RNA. Vandevenne, M.; O'Connell, M.; Helder, S.; Shepherd, N.; Matthews, J.; Kwan, A.; Segal, D.; and Mackay, J. Angewandte Chemie - International Edition, 53(30): 7848-7852. 2014.
doi   link   bibtex   abstract  
The structure of an LIM-Only protein 4 (LMO4) and Deformed Epidermal Autoregulatory Factor-1 (DEAF1) complex reveals a common mode of binding to LMO4. Joseph, S.; Kwan, A.; Stokes, P.; Mackay, J.; Cubeddu, L.; and Matthews, J. PLoS ONE, 9(10). 2014.
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Insight into the architecture of the NuRD complex: Structure of the RbAp48-MTA1 subcomplex. Alqarni, S.; Murthy, A.; Zhang, W.; Przewloka, M.; Silva, A.; Watson, A.; Lejon, S.; Pei, X.; Smits, A.; Kloet, S.; Mackay, J.; and Laue, E. Journal of Biological Chemistry, 289(32): 21844-21855. 2014.
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Structure of the hemoglobin-isdh complex reveals the molecular basis of iron capture by staphylococcus aureus. Dickson, C.; Kumar, K.; Jacques, D.; Malmirchegini, G.; Spirig, T.; Mackay, J.; Clubb, R.; Guss, J.; and Gell, D. Journal of Biological Chemistry, 289(10): 6728-6738. 2014.
doi   link   bibtex   abstract  
Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1. Joseph, S.; Kwan, A.; Mackay, J.; Cubeddu, L.; and Matthews, J. Biomolecular NMR Assignments, 8(1): 141-144. 2014.
doi   link   bibtex   abstract  
Trim58 Degrades Dynein and Regulates Terminal Erythropoiesis. Thom, C.; Traxler, E.; Khandros, E.; Nickas, J.; Zhou, O.; Lazarus, J.; Silva, A.; Prabhu, D.; Yao, Y.; Aribeana, C.; Holzbaur, E.; and Weiss, M. Developmental Cell, 30(6): 688-700. 2014.
doi   link   bibtex   abstract  
Transcription factor seeks DNA - Cognate site preferred. Mackay, J. Journal of Molecular Biology, 426(7): 1370-1372. 2014.
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1H, 13C and 15N resonance assignments of an N-terminal domain of CHD4. Silva, A.; Kwan, A.; and Mackay, J. Biomolecular NMR Assignments, 8(1): 137-139. 2014.
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  2013 (8)
α-Hemoglobin-stabilizing Protein (AHSP) perturbs the proximal heme pocket of oxy-α-hemoglobin and weakens the iron-oxygen bond. Dickson, C.; Rich, A.; D'Avigdor, W.; Collins, D.; Lowry, J.; Mollan, T.; Khandros, E.; Olson, J.; Weiss, M.; MacKay, J.; Lay, P.; and Gell, D. Journal of Biological Chemistry, 288(27): 19986-20001. 2013.
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Is there a telltale RH fingerprint in zinc fingers that recognizes methylated CpG dinucleotides?. Mackay, J.; Segal, D.; and Crossley, M. Trends in Biochemical Sciences, 38(9): 421-422. 2013.
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A structural analysis of DNA binding by myelin transcription factor 1 double zinc fingers. Gamsjaeger, R.; O'Connell, M.; Cubeddu, L.; Shepherd, N.; Lowry, J.; Kwan, A.; Vandevenne, M.; Swanton, M.; Matthews, J.; and Mackay, J. Journal of Biological Chemistry, 288(49): 35180-35191. 2013.
doi   link   bibtex   abstract  
New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217. Vandevenne, M.; Jacques, D.; Artuz, C.; Nguyen, C.; Kwan, A.; Segal, D.; Matthews, J.; Crossley, M.; Guss, J.; and MacKay, J. Journal of Biological Chemistry, 288(15): 10616-10627. 2013.
doi   link   bibtex   abstract  
Effects of calcium binding and the hypertrophic cardiomyopathy A8V mutation on the dynamic equilibrium between closed and open conformations of the regulatory N-domain of isolated cardiac troponin C. Cordina, N.; Liew, C.; Gell, D.; Fajer, P.; MacKay, J.; and Brown, L. Biochemistry, 52(11): 1950-1962. 2013.
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Structural basis of the interaction of the breast cancer Oncogene LMO4 with the tumour suppressor CtIP/RBBP8. Stokes, P.; Liew, C.; Kwan, A.; Foo, P.; Barker, H.; Djamirze, A.; O'Reilly, V.; Visvader, J.; Mackay, J.; and Matthews, J. Journal of Molecular Biology, 425(7): 1101-1110. 2013.
doi   link   bibtex   abstract  
Semiquantitative and quantitative analysis of protein-DNA interactions using steady-state measurements in surface plasmon resonance competition experiments. Gamsjaeger, R.; Kariawasam, R.; Bang, L.; Touma, C.; Nguyen, C.; Matthews, J.; Cubeddu, L.; and Mackay, J. Analytical Biochemistry, 440(2): 178-185. 2013.
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Analysis of disease-causing GATA1 mutations in murine gene complementation systems. Campbell, A.; Wilkinson-White, L.; MacKay, J.; Matthews, J.; and Blobel, G. Blood, 121(26): 5218-5227. 2013.
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  2012 (17)
Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry. McKenzie, J., L.; Duyvestyn, J., M.; Smith, T.; Bendak, K.; MacKay, J.; Cursons, R.; Cook, G., M.; and Arcus, V., L. RNA, 18(6): 1267-1278. 6 2012.
Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry [link]Website   doi   link   bibtex   abstract  
Interdomain orientation of cardiac Troponin C characterized by paramagnetic relaxation enhancement NMR reveals a compact state. Cordina, N., M.; Liew, C., K.; Gell, D., A.; Fajer, P., G.; Mackay, J., P.; and Brown, L., J. Protein Science, 21(9): 1376-1387. 9 2012.
Interdomain orientation of cardiac Troponin C characterized by paramagnetic relaxation enhancement NMR reveals a compact state [link]Website   doi   link   bibtex   abstract  
Backbone and sidechain 1H, 13C and 15N chemical shift assignments of the hydrophobin DewA from Aspergillus nidulans. Morris, V., K.; Kwan, A., H.; Mackay, J., P.; and Sunde, M. Biomolecular NMR Assignments, 6(1): 83-86. 4 2012.
Backbone and sidechain 1H, 13C and 15N chemical shift assignments of the hydrophobin DewA from Aspergillus nidulans [link]Website   doi   link   bibtex   abstract  
Solution structure of a tethered Lmo2 LIM2 /Ldb1 LID complex. Dastmalchi, S.; Wilkinson-White, L.; Kwan, A., H.; Gamsjaeger, R.; Mackay, J., P.; and Matthews, J., M. Protein Science, 21(11): 1768-1774. 11 2012.
Solution structure of a tethered Lmo2 LIM2 /Ldb1 LID complex [link]Website   doi   link   bibtex   abstract  
Solution structure of the LIM-homeodomain transcription factor complex Lhx3/Ldb1 and the effects of a pituitary mutation on key Lhx3 interactions. Bhati, M.; Lee, C.; Gadd, M.; Jeffries, C.; Kwan, A.; Whitten, A.; Trewhella, J.; Mackay, J.; and Matthews, J. PLoS ONE, 7(7). 2012.
doi   link   bibtex   abstract  
A rapid method for assessing the RNA-binding potential of a protein. Bendak, K.; Loughlin, F.; Cheung, V.; O'Connell, M.; Crossley, M.; and MacKay, J. Nucleic Acids Research, 40(14). 2012.
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Bivalent recognition of nucleosomes by the tandem PHD fingers of the CHD4 ATPase is required for CHD4-mediated repression. Musselman, C.; Ramiŕez, J.; Sims, J.; Mansfield, R.; Oliver, S.; Denu, J.; Mackay, J.; Wade, P.; Hagman, J.; and Kutateladze, T. Proceedings of the National Academy of Sciences of the United States of America, 109(3): 787-792. 2012.
doi   link   bibtex   abstract  
Two-timing zinc finger transcription factors liaising with RNA. Burdach, J.; O'Connell, M.; Mackay, J.; and Crossley, M. Trends in Biochemical Sciences, 37(5): 199-205. 2012.
doi   link   bibtex   abstract  
Solution structure of a tethered Lmo2LIM2/Ldb1LID complex. Dastmalchi, S.; Wilkinson-White, L.; Kwan, A.; Gamsjaeger, R.; Mackay, J.; and Matthews, J. Protein Science, 21(11): 1768-1774. 2012.
doi   link   bibtex   abstract  
Modular assembly of RanBP2-Type zinc finger domains to target single-stranded RNA. O'Connell, M.; Vandevenne, M.; Nguyen, C.; Matthews, J.; Gamsjaeger, R.; Segal, D.; and MacKay, J. Angewandte Chemie - International Edition, 51(22): 5371-5375. 2012.
doi   link   bibtex   abstract  
1H, 15N and 13C assignments of an intramolecular LMO4-LIM1/CtIP complex. Liew, C.; Kwan, A.; Stokes, P.; MacKay, J.; and Matthews, J. Biomolecular NMR Assignments, 6(1): 31-34. 2012.
doi   link   bibtex   abstract  
Synthesis of the bacteriocin glycopeptide sublancin 168 and S-glycosylated variants. Hsieh, Y.; Wilkinson, B.; O'Connell, M.; MacKay, J.; Matthews, J.; and Payne, R. Organic Letters, 14(7): 1910-1913. 2012.
doi   link   bibtex   abstract  
Backbone and sidechain 1H, 13C and 15N chemical shift assignments of the hydrophobin DewA from Aspergillus nidulans. Morris, V.; Kwan, A.; MacKay, J.; and Sunde, M. Biomolecular NMR Assignments, 6(1): 83-86. 2012.
doi   link   bibtex   abstract  
Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry. Mckenzie, J.; Duyvestyn, J.; Smith, T.; Bendak, K.; Mackay, J.; Cursons, R.; Cook, G.; and Arcus, V. RNA, 18(6): 1267-1278. 2012.
doi   link   bibtex   abstract  
Interdomain orientation of cardiac troponin C characterized by paramagnetic relaxation enhancement NMR reveals a compact state. Cordina, N.; Liew, C.; Gell, D.; Fajer, P.; Mackay, J.; and Brown, L. Protein Science, 21(9): 1376-1387. 2012.
doi   link   bibtex   abstract  
Self-assembly of functional, amphipathic amyloid monolayers by the fungal hydrophobin EAS. Macindoe, I.; Kwan, A.; Ren, Q.; Morris, V.; Yang, W.; Mackay, J.; and Sunde, M. Proceedings of the National Academy of Sciences of the United States of America, 109(14). 2012.
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The detection and quantitation of protein oligomerization. Gell, D.; Grant, R.; and MacKay, J. Volume 747 2012.
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  2011 (16)
Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1. Wilkinson-White, L.; Gamsjaeger, R.; Dastmalchi, S.; Wienert, B.; Stokes, P., H.; Crossley, M.; Mackay, J., P.; and Matthews, J., M. Proceedings of the National Academy of Sciences, 108(35): 14443-14448. 8 2011.
Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1 [link]Website   doi   link   bibtex   abstract  
Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes. Lamonica, J., M.; Deng, W.; Kadauke, S.; Campbell, A., E.; Gamsjaeger, R.; Wang, H.; Cheng, Y.; Billin, A., N.; Hardison, R., C.; Mackay, J., P.; and Blobel, G., A. Proceedings of the National Academy of Sciences, 108(22): E159-E168. 5 2011.
Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes [link]Website   doi   link   bibtex   abstract  
The multi-zinc finger protein ZNF217 contacts DNA through a two-finger domain. Nunez, N.; Clifton, M.; Funnell, A.; Artuz, C.; Hallal, S.; Quinlan, K.; Font, J.; Vandevenne, M.; Setiyaputra, S.; Pearson, R.; Mackay, J.; and Crossley, M. Journal of Biological Chemistry, 286(44): 38190-38201. 2011.
doi   link   bibtex   abstract  
Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes. Lamonica, J.; Deng, W.; Kadauke, S.; Campbell, A.; Gamsjaeger, R.; Wang, H.; Cheng, Y.; Billin, A.; Hardison, R.; Mackay, J.; Mackay, J.; and Blobel, G. Proceedings of the National Academy of Sciences of the United States of America, 108(22). 2011.
doi   link   bibtex   abstract  
Structural basis for hemoglobin capture by Staphylococcus aureus cell-surface protein, IsdH. Kumar, K.; Jacques, D.; Pishchany, G.; Caradoc-Davies, T.; Spirig, T.; Malmirchegini, G.; Langley, D.; Dickson, C.; Mackay, J.; Clubb, R.; Guss, J.; and Gell, D. Journal of Biological Chemistry, 286(44): 38439-38447. 2011.
doi   link   bibtex   abstract  
Protein-protein interactions: Analysis of a false positive GST pulldown result. Wissmueller, S.; Font, J.; Liew, C.; Cram, E.; Schroeder, T.; Turner, J.; Crossley, M.; Mackay, J.; and Matthews, J. Proteins: Structure, Function and Bioinformatics, 79(8): 2365-2371. 2011.
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Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3. Gamsjaeger, R.; Webb, S.; Lamonica, J.; Billin, A.; Blobel, G.; and Mackay, J. Molecular and Cellular Biology, 31(13): 2632-2640. 2011.
doi   link   bibtex   abstract  
Plant homeodomain (PHD) fingers of CHD4 are histone H3-binding modules with preference for unmodified H3K4 and methylated H3K9. Mansfield, R.; Musselman, C.; Kwan, A.; Oliver, S.; Garske, A.; Davrazou, F.; Denu, J.; Kutateladze, T.; and Mackay, J. Journal of Biological Chemistry, 286(13): 11779-11791. 2011.
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Characterization of a family of RanBP2-Type zinc fingers that can recognize single-stranded RNA. Nguyen, C.; Mansfield, R.; Leung, W.; Vaz, P.; Loughlin, F.; Grant, R.; and MacKay, J. Journal of Molecular Biology, 407(2): 273-283. 2011.
doi   link   bibtex   abstract  
Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1. Wilkinson-White, L.; Gamsjaeger, R.; Dastmalchi, S.; Wienert, B.; Stokes, P.; Crossley, M.; Mackay, J.; and Matthews, J. Proceedings of the National Academy of Sciences of the United States of America, 108(35): 14443-14448. 2011.
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Macromolecular NMR spectroscopy for the non-spectroscopist: Beyond macromolecular solution structure determination. Bieri, M.; Kwan, A.; Mobli, M.; King, G.; MacKay, J.; and Gooley, P. FEBS Journal, 278(5): 704-715. 2011.
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Erratum: The prospects for designer single-stranded RNA-binding proteins (Nature Structural and Molecular Biology (2011) 18 (256-261)). MacKay, J.; Font, J.; and Segal, D. Nature Structural and Molecular Biology, 18(4): 516. 2011.
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Macromolecular NMR spectroscopy for the non-spectroscopist. Kwan, A.; Mobli, M.; Gooley, P.; King, G.; and MacKay, J. FEBS Journal, 278(5): 687-703. 2011.
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Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex. Lejon, S.; Thong, S.; Murthy, A.; AlQarni, S.; Murzina, N.; Blobel, G.; Laue, E.; and Mackay, J. Journal of Biological Chemistry, 286(2): 1196-1203. 2011.
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The prospects for designer single-stranded RNA-binding proteins. MacKay, J.; Font, J.; and Segal, D. Nature Structural and Molecular Biology, 18(3): 256-261. 2011.
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The structure of a truncated phosphoribosylanthranilate isomerase suggests a unified model for evolution of the (βα)8 barrel fold. Setiyaputra, S.; MacKay, J.; and Patrick, W. Journal of Molecular Biology, 408(2): 291-303. 2011.
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  2010 (11)
Beyond DNA: Zinc Finger Domains as RNA-Binding Modules. Font, J.; and Mackay, J., P. Volume 649 . Methods in Molecular Biology, pages 479-491. 2010.
Methods in Molecular Biology [link]Website   doi   link   bibtex   abstract  
Protein Recognition. Mansfield, R., E.; Cross, A., J.; Matthews, J., M.; and Mackay, J., P. Volume 2 . Amino Acids, Peptides and Proteins in Organic Chemistry, pages 505-532. Wiley-VCH Verlag GmbH & Co. KGaA, 12 2010.
Amino Acids, Peptides and Proteins in Organic Chemistry [link]Website   doi   link   bibtex  
1H, 13C and 15N backbone and side chain resonance assignments of the N-terminal domain of the histidine kinase inhibitor KipI from Bacillus subtilis. Hynson, R., M., G.; Kwan, A., H.; Jacques, D., A.; Mackay, J., P.; and Trewhella, J. Biomolecular NMR Assignments, 4(2): 167-169. 10 2010.
1H, 13C and 15N backbone and side chain resonance assignments of the N-terminal domain of the histidine kinase inhibitor KipI from Bacillus subtilis [link]Website   doi   link   bibtex   abstract  
Two-state conformational equilibrium in the Par-4 leucine zipper domain. Schwalbe, M.; Dutta, K.; Libich, D., S.; Venugopal, H.; Claridge, J., K.; Gell, D., A.; Mackay, J., P.; Edwards, P., J., B.; and Pascal, S., M. Proteins: Structure, Function, and Bioinformatics, 78(11): n/a-n/a. 4 2010.
Two-state conformational equilibrium in the Par-4 leucine zipper domain [link]Website   doi   link   bibtex   abstract  
AHSP (α-haemoglobin-stabilizing protein) stabilizes apo-α-haemoglobin in a partially folded state. Krishna Kumar, K.; Dickson, C.; Weiss, M.; Mackay, J.; and Gell, D. Biochemical Journal, 432(2): 275-282. 2010.
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Beyond DNA: Zinc finger domains as RNA-binding modules. Font, J.; and MacKay, J. Volume 649 2010.
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Preface. MacKay, J.; and Segal, D. Volume 649 2010.
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1H, 15N and 13C assignments of an intramolecular Lmo2-LIM2/Ldb1-LID complex. Wilkinson-White, L.; Dastmalchi, S.; Kwan, A.; Ryan, D.; MacKay, J.; and Matthews, J. Biomolecular NMR Assignments, 4(2): 203-206. 2010.
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Two-state conformational equilibrium in the Par-4 leucine zipper domain. Schwalbe, M.; Dutta, K.; Libich, D.; Venugopal, H.; Claridge, J.; Gell, D.; Mackay, J.; Edwards, P.; and Pascal, S. Proteins: Structure, Function and Bioinformatics, 78(11): 2433-2449. 2010.
doi   link   bibtex   abstract  
1H, 13C and 15N backbone and side chain resonance assignments of the N-terminal domain of the histidine kinase inhibitor KipI from Bacillus subtilis. Hynson, R.; Kwan, A.; Jacques, D.; MacKay, J.; and Trewhella, J. Biomolecular NMR Assignments, 4(2): 167-169. 2010.
doi   link   bibtex   abstract  
Protein Recognition. Mansfield, R.; Cross, A.; Matthews, J.; and Mackay, J. Volume 2 2010.
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  2009 (11)
Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications. Musselman, C., A.; Mansfield, R., E.; Garske, A., L.; Davrazou, F.; Kwan, A., H.; Oliver, S., S.; O'Leary, H.; Denu, J., M.; Mackay, J., P.; and Kutateladze, T., G. Biochemical Journal, 423(2): 179-187. 10 2009.
Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications [link]Website   doi   link   bibtex   abstract  
The structural analysis of protein–protein interactions by NMR spectroscopy. O'Connell, M., R.; Gamsjaeger, R.; and Mackay, J., P. PROTEOMICS, 9(23): 5224-5232. 12 2009.
The structural analysis of protein–protein interactions by NMR spectroscopy [link]Website   doi   link   bibtex   abstract  
The structural analysis of protein-protein interactions by NMR spectroscopy. O'Connell, M.; Gamsjaeger, R.; and Mackay, J. Proteomics, 9(23): 5224-5232. 2009.
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Conformational Stability and DNA Binding Specificity of the Cardiac T-Box Transcription Factor Tbx20. Macindoe, I.; Glockner, L.; Vukašin, P.; Stennard, F.; Costa, M.; Harvey, R.; Mackay, J.; and Sunde, M. Journal of Molecular Biology, 389(3): 606-618. 2009.
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A cis-proline in α-hemoglobin stabilizing protein directs the structural reorganization of α-hemoglobin. Gell, D.; Feng, L.; Zhou, S.; Jeffrey, P.; Bendak, K.; Gow, A.; Weiss, M.; Shi, Y.; and Mackay, J. Journal of Biological Chemistry, 284(43): 29462-29469. 2009.
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Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications. Musselman, C.; Mansfield, R.; Garske, A.; Davrazou, F.; Kwan, A.; Oliver, S.; O'Leary, H.; Denu, J.; Mackay, J.; and Kutateladze, T. Biochemical Journal, 423(2): 179-187. 2009.
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Erratum: Structure and inhibition of orotidine 5#-Monophosphate decarboxylase from plasmodium falciparum (Biochemistry (2009) 48:11 (2570-2570) 10.1021/bi900043p). Langley, D.; Shojaei, M.; Chan, C.; Lok, H.; Mackay, J.; Traut, T.; Guss, J.; and Christopherson, R. Biochemistry, 48(11): 2570. 2009.
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A mass spectrometric investigation of the ability of metal complexes to modulate transcription factor activity. Talib, J.; Beck, J.; Urathamakul, T.; Nguyen, C.; Aldrich-Wright, J.; MacKay, J.; and Ralph, S. Chemical Communications, (37): 5546-5548. 2009.
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Structural analysis of MED-1 reveals unexpected diversity in the mechanism of DNA recognition by GATA-type zinc finger domains. Lowry, J.; Gamsjaeger, R.; Thong, S.; Hung, W.; Kwan, A.; Broitman-Maduro, G.; Matthews, J.; Maduro, M.; and Mackay, J. Journal of Biological Chemistry, 284(9): 5827-5835. 2009.
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The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5' splice site-like sequences. Loughlin, F.; Mansfield, R.; Vaz, P.; McGrath, A.; Setiyaputra, S.; Gamsjaeger, R.; Chen, E.; Morris, B.; Guss, J.; and Mackay, J. Proceedings of the National Academy of Sciences of the United States of America, 106(14): 5581-5586. 2009.
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It takes two to tango: The structure and function of LIM, RING, PHD and MYND domains. Matthews, J.; Bhati, M.; Lehtomaki, E.; Mansfield, R.; Cubeddu, L.; and Mackay, J. Current Pharmaceutical Design, 15(31): 3681-3696. 2009.
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  2008 (12)
Crystallization of a ZRANB2–RNA complex. Loughlin, F., E.; Lee, M.; Guss, J., M.; and Mackay, J., P. Acta Crystallographica Section F Structural Biology and Crystallization Communications, 64(12): 1175-1177. 12 2008.
Crystallization of a ZRANB2–RNA complex [link]Website   doi   link   bibtex   abstract  
NMR spectroscopy as a tool for the rapid assessment of the conformation of GST-fusion proteins. Chu, K.; Gamsjaeger, R.; Mansfield, R.; and Mackay, J. Protein Science, 17(9): 1630-1635. 2008.
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Structural analysis of hydrophobins. Sunde, M.; Kwan, A.; Templeton, M.; Beever, R.; and Mackay, J. Micron, 39(7): 773-784. 2008.
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The Cys3-Cys4 Loop of the Hydrophobin EAS Is Not Required for Rodlet Formation and Surface Activity. Kwan, A.; Macindoe, I.; Vukašin, P.; Morris, V.; Kass, I.; Gupte, R.; Mark, A.; Templeton, M.; Mackay, J.; and Sunde, M. Journal of Molecular Biology, 382(3): 708-720. 2008.
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Response to Chatr-aryamontri et al.: Protein interactions: to believe or not to believe?. Mackay, J.; Sunde, M.; Lowry, J.; Crossley, M.; and Matthews, J. Trends in Biochemical Sciences, 33(6): 242-243. 2008.
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Evolution of Quaternary Structure in a Homotetrameric Enzyme. Griffin, M.; Dobson, R.; Pearce, F.; Antonio, L.; Whitten, A.; Liew, C.; Mackay, J.; Trewhella, J.; Jameson, G.; Perugini, M.; Perugini, M.; and Gerrard, J. Journal of Molecular Biology, 380(4): 691-703. 2008.
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Implementing the LIM code: The structural basis for cell type-specific assembly of LIM-homeodomain complexes. Bhati, M.; Lee, C.; Nancarrow, A.; Lee, M.; Craig, V.; Bach, I.; Guss, J.; Mackay, J.; and Matthews, J. EMBO Journal, 27(14): 2018-2029. 2008.
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Structural and biophysical analysis of the DNA binding properties of myelin transcription factor 1. Gamsjaeger, R.; Swanton, M.; Kobus, F.; Lehtomaki, E.; Lowry, J.; Kwan, A.; Matthews, J.; and Mackay, J. Journal of Biological Chemistry, 283(8): 5158-5167. 2008.
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Structure and inhibition of orotidine 5′-monophosphate decarboxylase from Plasmodium falciparum. Langley, D.; Shojaei, M.; Chan, C.; Hiu, C.; Mackay, J.; Traut, T.; Guss, J.; and Christopherson, R. Biochemistry, 47(12): 3842-3854. 2008.
doi   link   bibtex   abstract  
Crystallization of a ZRANB2-RNA complex. Loughlin, F.; Lee, M.; Guss, J.; and Mackay, J. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 64(12): 1175-1177. 2008.
doi   link   bibtex   abstract  
Designed metal-binding sites in biomolecular and bioinorganic interactions. Matthews, J.; Loughlin, F.; and Mackay, J. Current Opinion in Structural Biology, 18(4): 484-490. 2008.
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Escherichia coli glucuronylsynthase: An engineered enzyme for the synthesis of β-glucuronides. Wilkinson, S.; Liew, C.; Mackay, J.; Salleh, H.; Withers, S.; and McLeod, M. Organic Letters, 10(8): 1585-1588. 2008.
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  2007 (7)
Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation. Porter, C.; Matthews, J.; Mackay, J.; Pursglove, S.; Schmidberger, J.; Leedman, P.; Pero, S.; Krag, D.; Wilce, M.; and Wilce, J. BMC Structural Biology, 7. 2007.
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Sticky fingers: zinc-fingers as protein-recognition motifs. Gamsjaeger, R.; Liew, C.; Loughlin, F.; Crossley, M.; and Mackay, J. Trends in Biochemical Sciences, 32(2): 63-70. 2007.
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Solution Structure of the THAP Domain from Caenorhabditis elegans C-terminal Binding Protein (CtBP). Liew, C.; Crossley, M.; Mackay, J.; and Nicholas, H. Journal of Molecular Biology, 366(2): 382-390. 2007.
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An erythroid chaperone that facilitates folding of α-globin subunits for hemoglobin synthesis. Yu, X.; Kong, Y.; Dore, L.; Abdulmalik, O.; Katein, A.; Zhou, S.; Choi, J.; Gell, D.; Mackay, J.; Gow, A.; Gow, A.; and Weiss, M. Journal of Clinical Investigation, 117(7): 1856-1865. 2007.
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Mutations in crdiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy. Kirk, E.; Sunde, M.; Costa, M.; Rankin, S.; Wolstein, O.; Castro, M.; Butler, T.; Hyun, C.; Guo, G.; Otway, R.; Winlaw, D.; and Harvey, R. American Journal of Human Genetics, 81(2): 280-291. 2007.
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Protein interactions: is seeing believing?. Mackay, J.; Sunde, M.; Lowry, J.; Crossley, M.; and Matthews, J. Trends in Biochemical Sciences, 32(12): 530-531. 2007.
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Crystal structures of flax rust avirulence proteins AvrL567-A and -D reveal details of the structural basis for flax disease resistance specificity. Wang, C.; Gunčar, G.; Forwood, J.; Teh, T.; Catanzariti, A.; Lawrence, G.; Loughlin, F.; Mackay, J.; Schirra, H.; Anderson, P.; Dodds, P.; and Kobe, B. Plant Cell, 19(9): 2898-2912. 2007.
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  2006 (10)
Structural basis for rodlet assembly in fungal hydrophobins. Kwan, A., H., Y.; Winefield, R., D.; Sunde, M.; Matthews, J., M.; Haverkamp, R., G.; Templeton, M., D.; and Mackay, J., P. Proceedings of the National Academy of Sciences, 103(10): 3621-3626. 3 2006.
Structural basis for rodlet assembly in fungal hydrophobins [link]Website   doi   link   bibtex   abstract  
A Novel Haem-binding Interface in the 22 kDa Haem-binding Protein p22HBP. Gell, D., A.; Westman, B., J.; Gorman, D.; Liew, C.; Welch, J., J.; Weiss, M., J.; and Mackay, J., P. Journal of Molecular Biology, 362(2): 287-297. 9 2006.
A Novel Haem-binding Interface in the 22 kDa Haem-binding Protein p22HBP [link]Website   doi   link   bibtex   abstract  
GATA-1: One protein, many partners. Lowry, J., A.; and Mackay, J., P. The International Journal of Biochemistry & Cell Biology, 38(1): 6-11. 1 2006.
GATA-1: One protein, many partners [link]Website   doi   link   bibtex   abstract  
Zinc fingers are known as domains for binding DNA and RNA. Do they also mediate protein-protein interactions?. Loughlin, F.; and Mackay, J. IUBMB Life, 58(12): 731-733. 2006.
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Molecular analysis of the interaction between the hematopoietic master transcription factors GATA-1 and PU. Chu, W.; Rand, K.; Simpson, R.; Yung, W.; Mansfield, R.; Crossley, M.; Prœtorius-Ibba, M.; Nerlov, C.; Poulsen, F.; and Mackay, J. Journal of Biological Chemistry, 281(38): 28296-28306. 2006.
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Identification of the Key LMO2-binding Determinants on Ldb1. Ryan, D.; Sunde, M.; Kwan, A.; Marianayagam, N.; Nancarrow, A.; vanden Hoven, R.; Thompson, L.; Baca, M.; Mackay, J.; Visvader, J.; Visvader, J.; and Matthews, J. Journal of Molecular Biology, 359(1): 66-75. 2006.
doi   link   bibtex   abstract  
Structural basis for rodlet assembly in fungal hydrophobins. Kwan, A.; Winefield, R.; Sunde, M.; Matthews, J.; Haverkamp, R.; Templeton, M.; and Mackay, J. Proceedings of the National Academy of Sciences of the United States of America, 103(10): 3621-3626. 2006.
doi   link   bibtex   abstract  
Analysis of the structure and function of the transcriptional coregulator HOP. Kook, H.; Yung, W.; Simpson, R.; Kee, H.; Shin, S.; Lowry, J.; Loughlin, F.; Yin, Z.; Epstein, J.; and Mackay, J. Biochemistry, 45(35): 10584-10590. 2006.
doi   link   bibtex   abstract  
A Novel Haem-binding Interface in the 22 kDa Haem-binding Protein p22HBP. Gell, D.; Westman, B.; Gorman, D.; Liew, C.; Welch, J.; Weiss, M.; and Mackay, J. Journal of Molecular Biology, 362(2): 287-297. 2006.
doi   link   bibtex   abstract  
GATA-1: One protein, many partners. Lowry, J.; and MacKay, J. International Journal of Biochemistry and Cell Biology, 38(1): 6-11. 2006.
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  2005 (12)
Zinc fingers as protein recognition motifs: Structural basis for the GATA-1/Friend of GATA interaction. Liew, C., K.; Simpson, R., J., Y.; Kwan, A., H., Y.; Crofts, L., A.; Loughlin, F., E.; Matthews, J., M.; Crossley, M.; and Mackay, J., P. Proceedings of the National Academy of Sciences, 102(3): 583-588. 1 2005.
Zinc fingers as protein recognition motifs: Structural basis for the GATA-1/Friend of GATA interaction [link]Website   doi   link   bibtex   abstract  
Grb7-SH2 domain dimerisation is affected by a single point mutation. Porter, C., J.; Wilce, M., C., J.; Mackay, J., P.; Leedman, P.; and Wilce, J., A. European biophysics journal : EBJ, 34(5): 454-60. 7 2005.
Grb7-SH2 domain dimerisation is affected by a single point mutation. [link]Website   doi   link   bibtex   abstract  
Grb7-SH2 domain dimerisation is affected by a single point mutation. Porter, C.; Wilce, M.; Mackay, J.; Leedman, P.; and Wilce, J. European Biophysics Journal, 34(5): 454-460. 2005.
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Structure of oxidized α-haemoglobin bound to AHSP reveals a protective mechanism for haem. Feng, L.; Zhou, S.; Gu, L.; Gell, D.; Mackay, J.; Weiss, M.; Gow, A.; and Shi, Y. Nature, 435(7042): 697-701. 2005.
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1H, 15N and 13C assignments of an intramolecular Lhx3:ldb1 complex [4]. Lee, C.; Nancarrow, A.; Bach, I.; Mackay, J.; and Matthews, J. Journal of Biomolecular NMR, 33(3): 198. 2005.
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Zinc fingers as protein recognition motifs: Structural basis for the GATA-1/friend of GATA interaction. Liew, C.; Simpson, R.; Kwan, A.; Crofts, L.; Loughlin, F.; Matthews, J.; Crossley, M.; and Mackay, J. Proceedings of the National Academy of Sciences of the United States of America, 102(3): 583-588. 2005.
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Assessment of the robustness of a serendipitous zinc binding fold: Mutagenesis and protein grafting. Sharpe, B.; Liew, C.; Kwan, A.; Wilce, J.; Crossley, M.; Matthews, J.; and Mackay, J. Structure, 13(2): 257-266. 2005.
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Solution structure of a recombinant type I sculpin antifreeze protein. Kwan, A.; Fairley, K.; Anderberg, P.; Liew, C.; Harding, M.; and Mackay, J. Biochemistry, 44(6): 1980-1988. 2005.
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Role of alpha hemoglobin-stabilizing protein in normal erythropoiesis and β-thalassemia. Weiss, M.; Zhou, S.; Feng, L.; Gell, D.; Mackay, J.; Shi, Y.; and Gow, A. Volume 1054 2005.
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The hydrophobic domain 26 of human tropoelastin is unstructured in solution. MacKay, J.; Muiznieks, L.; Toonkool, P.; and Weiss, A. Journal of Structural Biology, 150(2): 154-162. 2005.
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A complex mechanism determines polarity of DNA replication fork arrest by the replication terminator complex of Bacillus subtilis. Duggin, I.; Matthews, J.; Dixon, N.; Wake, R.; and Mackay, J. Journal of Biological Chemistry, 280(13): 13105-13113. 2005.
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CSL: A notch above the rest. Pursglove, S.; and Mackay, J. International Journal of Biochemistry and Cell Biology, 37(12): 2472-2477. 2005.
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  2004 (9)
Presence of transient helical segments in the galanin-like peptide evident from 1H NMR, circular dichroism, and prediction studies. Dastmalchi, S.; Church, W.; Morris, M., B.; Iismaa, T., P.; and Mackay, J., P. Journal of Structural Biology, 146(3): 261-271. 6 2004.
Presence of transient helical segments in the galanin-like peptide evident from 1H NMR, circular dichroism, and prediction studies [link]Website   doi   link   bibtex   abstract  
Molecular mechanism of AHSP-mediated stabilization of α-hemoglobin. Feng, L.; Gell, D.; Zhou, S.; Gu, L.; Kong, Y.; Li, J.; Hu, M.; Yan, N.; Lee, C.; Rich, A.; MacKay, J.; and Shi, Y. Cell, 119(5): 629-640. 2004.
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Classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3. Simpson, R.; Lee, S.; Bartle, N.; Sum, E.; Visvader, J.; Matthews, J.; Mackay, J.; and Crossley, M. Journal of Biological Chemistry, 279(38): 39789-39797. 2004.
doi   link   bibtex   abstract  
Presence of transient helical segments in the galanin-like peptide evident from 1H NMR, circular dichroism, and prediction studies. Dastmalchi, S.; Church, W.; Morris, M.; Iismaa, T.; and Mackay, J. Journal of Structural Biology, 146(3): 261-271. 2004.
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Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3. Chow, M.; MacKay, J.; Whisstock, J.; Scanlon, M.; and Bottomley, S. Biochemical and Biophysical Research Communications, 322(2): 387-394. 2004.
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Crystal and Solution Structures of a Superantigen from Yersinia pseudotuberculosis Reveal a Yelly-Roll Fold. Donadini, R.; Liew, C.; Kwan, A.; Mackay, J.; and Fields, B. Structure, 12(1): 145-156. 2004.
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Loss of α-hemoglobin-stabilizing protein impairs erythropoiesis and exacerbates β-thalassemia. Kong, Y.; Zhou, S.; Kihm, A.; Katein, A.; Yu, X.; Gell, D.; Mackay, J.; Adachi, K.; Foster-Brown, L.; Louden, C.; Gow, A.; and Weiss, M. Journal of Clinical Investigation, 114(10): 1457-1466. 2004.
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Structural studies on a protein-binding zinc-finger domain of eos reveal both similarities and differences to classical zinc fingers. Westman, B.; Perdomo, J.; Matthews, J.; Crossley, M.; and Mackay, J. Biochemistry, 43(42): 13318-13327. 2004.
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TC-1 Is a Novel Tumorigenic and Natively Disordered Protein Associated with Thyroid Cancer. Sunde, M.; McGrath, K.; Young, L.; Matthews, J.; Chua, E.; Mackay, J.; and Death, A. Cancer Research, 64(8): 2766-2773. 2004.
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  2003 (8)
The C-terminal Domain of Eos Forms a High Order Complex in Solution. Westman, B.; Perdomo, J.; Sunde, M.; Crossley, M.; and Mackay, J. Journal of Biological Chemistry, 278(43): 42419-42426. 2003.
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Pentaprobe: a comprehensive sequence for the one-step detection of DNA-binding activities. Kwan, A.; Czolij, R.; Mackay, J.; and Crossley, M. Nucleic acids research, 31(20). 2003.
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The structure of the zinc finger domain from human splicing factor ZNF265 fold. Plambeck, C.; Kwan, A.; Adams, D.; Westman, B.; Van der Weyden, L.; Medcalf, R.; Morris, B.; and Mackay, J. Journal of Biological Chemistry, 278(25): 22805-22811. 2003.
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Structural basis for the recognition of Idb1 by the N-terminal LIM domains of LMO2 and LMO4. Deane, J.; Mackay, J.; Kwan, A.; Sum, E.; Visvader, J.; and Matthews, J. EMBO Journal, 22(9): 2224-2233. 2003.
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Engineering a protein scaffold from a PHD finger. Kwan, A.; Gell, D.; Verger, A.; Crossley, M.; Matthews, J.; and Mackay, J. Structure, 11(7): 803-813. 2003.
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Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop. Kook, H.; Lepore, J.; Gitler, A.; Lu, M.; Yung, W.; Mackay, J.; Zhou, R.; Ferrari, V.; Gruber, P.; and Epstein, J. Journal of Clinical Investigation, 112(6): 863-871. 2003.
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CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions. Simpson, R.; Cram, E.; Czolij, R.; Matthews, J.; Crossley, M.; and Mackay, J. Journal of Biological Chemistry, 278(30): 28011-28018. 2003.
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Solution structure and behaviour of Δ-m-α-[Ru(R,R- picchxnMe2)(phi)]2+ by NMR spectroscopy and molecular modelling. Proudfoot, E.; Mackay, J.; and Karuso, P. Dalton Transactions, (2): 165-170. 2003.
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  2002 (13)
Ikaros: a key regulator of haematopoiesis. Westman, B., J.; Mackay, J., P.; and Gell, D. The International Journal of Biochemistry & Cell Biology, 34(10): 1304-1307. 10 2002.
Ikaros: a key regulator of haematopoiesis [link]Website   doi   link   bibtex   abstract  
Biophysical characterization of the α-globin binding protein α-hemoglobin stabilizing protein. Dvid, G.; Yi, K.; Eaton A, S.; Weiss C, M.; and Mackay E, J. Journal of Biological Chemistry, 277(43): 40602-40609. 2002.
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A new zinc binding fold underlines the versatility of zinc binding modules in protein evolution. Sharpe, B.; Matthews, J.; Kwan, A.; Newton, A.; Gell, D.; Crossley, M.; and Mackay, J. Structure, 10(5): 639-648. 2002.
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1H, 15N and 13C assignments of FLIN4, an intramolecular LMO4:ldb1 complex [8]. Deane, J.; Visvader, J.; Mackay, J.; and Matthews, J. Journal of Biomolecular NMR, 23(2): 165-166. 2002.
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Solution structure of a hydrophobic analogue of the winter flounder antifreeze protein. Liepinsh, E.; Otting, G.; Harding, M.; Ward, L.; Mackay, J.; and Haymet, A. European Journal of Biochemistry, 269(4): 1259-1266. 2002.
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Ikaros: A key regulator of haematopoiesis. Westman, B.; Mackay, J.; and Gell, D. International Journal of Biochemistry and Cell Biology, 34(10): 1304-1307. 2002.
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Characterization of the conserved interaction between GATA and FOG family proteins. Kowalski, K.; Liew, C.; Matthews, J.; Gell, D.; Crossley, M.; and Mackay, J. Journal of Biological Chemistry, 277(38): 35720-35729. 2002.
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Characterization of the conserved interaction between GATA and FOG family proteins. Kowalski, K.; Liew, C.; Matthews, J.; Gell, D.; Crossley, M.; and Mackay, J. Journal of Biological Chemistry, 277(38): 35720-35729. 2002.
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The Bacillus subtilis cell division proteins FtsL and DivIC are intrinsically unstable and do not interact with one another in the absence of other septasomal components. Robson, S.; Michie, K.; Mackay, J.; Harry, E.; and King, G. Molecular Microbiology, 44(3): 663-674. 2002.
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Hop is an unusual homeobox gene that modulates cardiac development. Chen, F.; Kook, H.; Milewski, R.; Gitler, A.; Lu, M.; Li, J.; Nazarian, R.; Schnepp, R.; Jen, K.; Biben, C.; Mullins, M.; and Epstein, J. Cell, 110(6): 713-723. 2002.
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Siah ubiquitin ligase is structurally related to traf and modulates tnf-α signaling. Polekhina, G.; House, C.; Traficante, N.; Mackay, J.; Relaix, F.; Sassoon, D.; Parker, M.; and Bowtell, D. Nature Structural Biology, 9(1): 68-75. 2002.
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Type I shorthorn sculpin antifreeze protein: Recombinant synthesis, solution conformation, and ice growth inhibition studies. Fairley, K.; Westman, B.; Pham, L.; Haymet, A.; Harding, M.; and Mackay, J. Journal of Biological Chemistry, 277(27): 24073-24080. 2002.
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The solution structure and intramolecular associations of the Tec kinase Src homology 3 domain. Pursglove, S.; Mulhern, T.; Mackay, J.; Hinds, M.; and Booker, G. Journal of Biological Chemistry, 277(1): 755-762. 2002.
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  2001 (7)
The Hydrophobin EAS Is Largely Unstructured in Solution and Functions by Forming Amyloid-Like Structures. Mackay, J., P.; Matthews, J., M.; Winefield, R., D.; Mackay, L., G.; Haverkamp, R., G.; and Templeton, M., D. Structure, 9(2): 83-91. 2 2001.
The Hydrophobin EAS Is Largely Unstructured in Solution and Functions by Forming Amyloid-Like Structures [link]Website   doi   link   bibtex   abstract  
The hydrophobin EAS is largely unstructured in solution and functions by forming amyloid-like structures. Mackay, J.; Matthews, J.; Winefield, R.; Mackay, L.; Haverkamp, R.; and Templeton, M. Structure, 9(2): 83-91. 2001.
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Discovery and Structure of a Potent and Highly Specific Blocker of Insect Calcium Channels. Wang, X.; Connor, M.; Wilson, D.; Wilson, H.; Nicholson, G.; Smith, R.; Shaw, D.; Mackay, J.; Alewood, P.; Christie, M.; Christie, M.; and King, G. Journal of Biological Chemistry, 276(43): 40306-40312. 2001.
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Design, production and characterization of FLIN2 and FLIN4: The engineering of intramolecular ldb1:LMO complexes. Deane, J.; Sum, E.; Mackay, J.; Lindeman, G.; Visvader, J.; and Matthews, J. Protein Engineering, 14(7): 493-499. 2001.
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1H, 15N and 13C assignments of FLIN2, an intramolecular LMO2:ldb1 complex [2]. Matthews, J.; Visvader, J.; and Mackay, J. Journal of Biomolecular NMR, 21(4): 385-386. 2001.
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Probing site specificity of DNA binding metallointercalators by NMR spectroscopy and molecular modeling. Proudfoot, E.; Mackay, J.; and Karuso, P. Biochemistry, 40(15): 4867-4878. 2001.
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The N-terminal Zinc Finger of the Erythroid Transcription Factor GATA-1 Binds GATC Motifs in DNA. Newton, A.; Mackay, J.; and Crossley, M. Journal of Biological Chemistry, 276(38): 35794-35801. 2001.
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  2000 (6)
Solution Structures of Two CCHC Zinc Fingers from the FOG Family Protein U-Shaped that Mediate Protein–Protein Interactions. Liew, C., K.; Kowalski, K.; Fox, A., H.; Newton, A.; Sharpe, B., K.; Crossley, M.; and Mackay, J., P. Structure, 8(11): 1157-1166. 11 2000.
Solution Structures of Two CCHC Zinc Fingers from the FOG Family Protein U-Shaped that Mediate Protein–Protein Interactions [link]Website   doi   link   bibtex   abstract  
The transactivation domain within cysteine/histidine-rich region 1 of CBP comprises two novel zinc-binding modules. Newton, A.; Sharped, B.; Kwan, A.; Mackay, J.; and Crossley, M. Journal of Biological Chemistry, 275(20): 15128-15134. 2000.
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The core of the respiratory syncytial virus fusion protein is a trimeric coiled coil. Matthews, J.; Young, T.; Tucker, S.; and Mackay, J. Journal of Virology, 74(13): 5911-5920. 2000.
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Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions. Chu Kong Liew; Kowalski, K.; Fox, A.; Newton, A.; Sharpe, B.; Crossley, M.; and Mackay, J. Structure, 8(11): 1157-1166. 2000.
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Interfacial asparagine residues within an amide tetrad contribute to Max helix-loop-helix leucine zipper homodimer stability. Tchan, M.; Choy, K.; Mackay, J.; Lyons, A.; Bains, N.; and Weiss, A. Journal of Biological Chemistry, 275(48): 37454-37461. 2000.
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A class of zinc fingers involved in protein-protein interactions. Matthews, J.; Kowalski, K.; Liew, C.; Sharpe, B.; Fox, A.; Crossley, M.; and Mackay, J. European Journal of Biochemistry, 267(4): 1030-1038. 2000.
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  1999 (6)
The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG. Kowalski, K.; Czolij, R.; King, G., F.; Crossley, M.; and Mackay, J., P. Journal of Biomolecular NMR, 13(3): 249-62. 3 1999.
The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG. [link]Website   doi   link   bibtex   abstract  
The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG. Kowalski, K.; Czolij, R.; King, G.; Crossley, M.; and Mackay, J. Journal of Biomolecular NMR, 13(3): 249-262. 1999.
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The dimerization and topological specificity functions of MinE reside in a structurally autonomous C-terminal domain. King, G.; Rowland, S.; Pan, B.; Mackay, J.; Mullen, G.; and Rothfield, L. Molecular Microbiology, 31(4): 1161-1169. 1999.
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Autonomous folding of a peptide corresponding to the N-terminal β- hairpin from ubiquitin. Zerella, R.; Evans, P.; Ionides, J.; Packman, L.; Trotter, B.; Mackay, J.; and Williams, D. Protein Science, 8(6): 1320-1331. 1999.
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Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers. Fox, A.; Liew, C.; Holmes, M.; Kowalski, K.; Mackay, J.; and Crossley, M. EMBO Journal, 18(10): 2812-2822. 1999.
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Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: The GATA-1:FOG complex. Crispino, J.; Lodish, M.; MacKay, J.; and Orkin, S. Molecular Cell, 3(2): 219-228. 1999.
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  1998 (5)
The C-terminal region of the stalk domain of ubiquitous human kinesin heavy chain contains the binding site for kinesin light chain. Diefenbach, R.; Mackay, J.; Armati, P.; and Cunningham, A. Biochemistry, 37(47): 16663-16670. 1998.
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Key residues characteristic of GATA N-fingers are recognized by FOG. Fox, A.; Kowalski, K.; King, G.; Mackay, J.; and Crossley, M. Journal of Biological Chemistry, 273(50): 33595-33603. 1998.
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Zinc fingers are sticking together. Mackay, J.; and Crossley, M. Trends in Biochemical Sciences, 23(1): 1-4. 1998.
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Interactions of the Antitumor Agent Molybdocene Dichloride with Oligonucleotides. Harding, M.; Mokdsi, G.; Mackay, J.; Prodigalidad, M.; and Lucas, S. Inorganic Chemistry, 37(10): 2432-2437. 1998.
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Involvement of the N-finger in the self-association of GATA-1. Mackay, J.; Kowalski, K.; Fox, A.; Czolij, R.; King, G.; and Crossley, M. Journal of Biological Chemistry, 273(46): 30560-30567. 1998.
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  1997 (8)
DNA-binding studies of XSPTSPSZ, derivatives of the intercalating heptad repeat of RNA polymerase II. Harding, M., M.; Krippner, G., Y.; Shelton, C., J.; Rodger, A.; Sanders, K., J.; Mackay, J., P.; and Prakash, A., S. Biopolymers, 42(4): 387-398. 10 1997.
DNA-binding studies of XSPTSPSZ, derivatives of the intercalating heptad repeat of RNA polymerase II [link]Website   doi   link   bibtex   abstract  
Measuring macromolecular diffusion using heteronuclear multiple-quantum pulsed-field-gradient NMR. Dingley, A., J.; Mackay, J., P.; Shaw, G., L.; Hambly, B., D.; and King, G., F. Journal of Biomolecular NMR, 10(1): 1-8. 1997.
Measuring macromolecular diffusion using heteronuclear multiple-quantum pulsed-field-gradient NMR [link]Website   doi   link   bibtex   abstract   1 download  
Zipping up transcription factors: Rational design of anti-Jun and anti-Fos peptides. Bains, N.; Wilce, J.; Heuer, K.; Tunstall, M.; Mackay, J.; Bennett, M.; Weiss, A.; and King, G. International Journal of Peptide Research and Therapeutics, 4(2): 67-77. 1997.
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Measuring macromolecular diffusion using heteronuclear multiple-quantum pulsed-field-gradient NMR. Dingley, A.; Mackay, J.; Shaw, G.; Hambly, B.; and King, G. Journal of Biomolecular NMR, 10(1): 1-8. 1997.
doi   link   bibtex   abstract   1 download  
The structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel. Fletcher, J.; Chapman, B.; Mackay, J.; Howden, M.; and King, G. Structure, 5(11): 1525-1535. 1997.
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Zipping up transcription factors: Rational design of anti-Jun and anti-Fos peptides. Bains, N.; Wilce, J.; Heuer, K.; Tunstall, M.; Mackay, J.; Bennett, M.; Weiss, A.; and King, G. Letters in Peptide Science, 4(2): 67-77. 1997.
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DMA-binding studies of XSPTSPSZ, derivatives of the intercalating heptad repeat of RNA polymerase II. Harding, M.; Krippner, G.; Shelton, C.; Rodger, A.; Sanders, K.; Mackay, J.; and Prakash, A. Biopolymers - Nucleic Acid Sciences Section, 42(4): 387-398. 1997.
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Δ-cis-α-[Ru(RR-picchxnMe2)(phen)]2+ shows minor groove AT selectivity with oligonucleotides. Proudfoot, E.; Mackay, J.; Vagg, R.; Vickery, K.; Williams, P.; and Karuso, P. Chemical Communications, (17): 1623-1624. 1997.
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  1996 (3)
Assignment of the 1H NMR spectrum and solution conformation of the antitumour antibiotic ditrisarubicin B. Mackay, J.; Shelton, C.; and Harding, M. Tetrahedron, 52(15): 5617-5624. 1996.
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Backbone dynamics of the c-Jun leucine zipper: 15N NMR relaxation studies. Mackay, J.; Shaw, G.; and King, G. Biochemistry, 35(15): 4867-4877. 1996.
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Development of a sensitive peptide-based immunoassay: Application to detection of the Jun and Fos oncoproteins. Heuer, K.; Mackay, J.; Podzebenko, P.; Bains, N.; Weiss, A.; King, G.; and Easterbrook-Smith, S. Biochemistry, 35(28): 9069-9075. 1996.
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  1995 (1)
Measuring protein self-association using pulsed-field-gradient NMR spectroscopy: Application to myosin light chain 2. Dingley, A.; Mackay, J.; Chapman, B.; Morris, M.; Kuchel, P.; Hambly, B.; and King, G. Journal of Biomolecular NMR, 6(3): 321-328. 1995.
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  1994 (4)
Functional roles of natural products: The involvement of extended arrays of weak interactions in cooperative binding phenomena. Williams, D.; Searle, M.; Groves, P.; Mackay, J.; Westwell, M.; Beauregard, D.; and Cristofaro, M. Pure and Applied Chemistry, 66(10-11): 1975-1982. 1994.
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Dissection of the Contributions toward Dimerization of Glycopeptide Antibiotics. Mackay, J.; Gerhard, U.; Beauregard, D.; Maplestone, R.; and Williams, D. Journal of the American Chemical Society, 116(11): 4573-4580. 1994.
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Glycopeptide Antibiotic Activity and the Possible Role of Dimerization: A Model for Biological Signaling. Mackay, J.; Gerhard, U.; Beauregard, D.; Westwell, M.; Searle, M.; and Williams, D. Journal of the American Chemical Society, 116(11): 4581-4590. 1994.
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The structure of an asymmetric dimer relevant to the mode of action of the glycopeptide antibiotics. Groves, P.; Searle, M.; Mackay, J.; and Williams, D. Structure, 2(8): 747-754. 1994.
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  1993 (3)
Toward an estimation of binding constants in aqueous solution: studies of associations of vancomycin group antibiotics. Williams, D., H.; Searle, M., S.; Mackay, J., P.; Gerhard, U.; and Maplestone, R., A. Proceedings of the National Academy of Sciences, 90(4): 1172-1178. 2 1993.
Toward an estimation of binding constants in aqueous solution: studies of associations of vancomycin group antibiotics. [link]Website   doi   link   bibtex   abstract  
The Role of the Sugar and Chlorine Substituents in the Dimerization of Vancomycin Antibiotics. Gerhard, U.; Mackay, J.; Maplestone, R.; and Williams, D. Journal of the American Chemical Society, 115(1): 232-237. 1993.
doi   link   bibtex   abstract   3 downloads  
Toward an estimation of binding constants in aqueous solution: Studies of associations of vancomycin group antibiotics. Williams, D.; Searle, M.; Mackay, J.; Gerhard, U.; and Maplestone, R. Proceedings of the National Academy of Sciences of the United States of America, 90(4): 1172-1178. 1993.
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