@article{
 title = {Memantine hydrochloride: a drug to be repurposed against Chikungunya virus?},
 type = {article},
 year = {2021},
 websites = {https://doi.org/10.1007/s43440-021-00216-4},
 id = {ce220b91-586e-32c8-955b-c110c06b5bbe},
 created = {2021-02-03T17:38:42.598Z},
 file_attached = {false},
 profile_id = {6d4e9e22-09e3-3340-83ee-25b0de1090e1},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2021-02-03T17:38:42.598Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 citation_key = {Pereira2021},
 source_type = {JOUR},
 private_publication = {false},
 abstract = {Chikungunya fever is an endemic disease caused by the Chikungunya virus (CHIKV) to which there is no vaccine or effective antiviral drug treatment so far. Our study aimed to evaluate the potential anti-CHIKV activity of memantine hydrochloride (mtnH), a drug from the class of the aminoadamantanes approved for the treatment of Alzheimer´s disease, as a possible drug to be repurposed to the treatment of Chikungunya fever.},
 bibtype = {article},
 author = {Pereira, Anna Karla dos Santos and Santos, Igor A and da Silva, Washington W and Nogueira, Flávia A Resende and Bergamini, Fernando R G and Jardim, Ana Carolina G and Corbi, Pedro P},
 doi = {10.1007/s43440-021-00216-4},
 journal = {Pharmacological Reports}
}

Chikungunya fever is an endemic disease caused by the Chikungunya virus (CHIKV) to which there is no vaccine or effective antiviral drug treatment so far. Our study aimed to evaluate the potential anti-CHIKV activity of memantine hydrochloride (mtnH), a drug from the class of the aminoadamantanes approved for the treatment of Alzheimer´s disease, as a possible drug to be repurposed to the treatment of Chikungunya fever.

@article{
 title = {Silver complexes with fluoroanthranilic acid isomers: Spectroscopic characterization, antimycobacterial activity and cytotoxic studies over a panel of tumor cells},
 type = {article},
 year = {2020},
 pages = {119293},
 volume = {502},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S0020169319315750},
 month = {3},
 id = {f7f0be72-c3a3-3121-9ff0-953b6a0be3aa},
 created = {2020-07-23T00:23:11.077Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2020-07-23T00:23:11.077Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Manzano, Carlos M. and Nakahata, Douglas H. and Tenorio, Juan C. and Lustri, Wilton R. and Resende Nogueira, Flávia A. and Aleixo, Nadia A. and da Silva Gomes, Pietra S. and Pavan, Fernando R. and Grecco, Julia A. and Ribeiro, Camila M. and Corbi, Pedro P.},
 doi = {10.1016/j.ica.2019.119293},
 journal = {Inorganica Chimica Acta}
}

@article{
 title = {Copper transporter 1 affinity as a delivery strategy to improve the cytotoxic profile of rationally designed copper(II) complexes for cancer treatment},
 type = {article},
 year = {2020},
 pages = {104922},
 volume = {67},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S0887233320304720},
 month = {9},
 id = {8d411d4b-0fdb-3bd2-a141-faf783707555},
 created = {2020-07-23T00:23:11.387Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2020-07-23T00:23:11.387Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Teles, Ramon Handerson Gomes and Graminha, Angelica Ellen and Rivera-Cruz, Cosette M. and Nakahata, Douglas Hideki and Formiga, André Luiz Barboza and Corbi, Pedro Paulo and Figueiredo, Marxa Leão and Cominetti, Márcia Regina},
 doi = {10.1016/j.tiv.2020.104922},
 journal = {Toxicology in Vitro}
}

@article{
 title = {Synthesis, crystal structures, DFT studies, antibacterial assays and interaction assessments with biomolecules of new platinum( <scp>ii</scp> ) complexes with adamantane derivatives},
 type = {article},
 year = {2020},
 pages = {11546-11556},
 volume = {44},
 websites = {http://xlink.rsc.org/?DOI=D0NJ02009E},
 id = {865ca4fb-bf3c-3652-8f24-c43576104e64},
 created = {2020-07-23T00:23:11.618Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2020-07-23T00:23:11.618Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 abstract = {Synthesis, crystal structures and antibacterial activities of new Pt( ii ) complexes with adamantane derivatives are presented in this article.},
 bibtype = {article},
 author = {Pereira, Anna Karla dos Santos and Manzano, Carlos Marrote and Nakahata, Douglas Hideki and Clavijo, Juan Carlos Tenorio and Pereira, Douglas Henrique and Lustri, Wilton Rogério and Corbi, Pedro Paulo},
 doi = {10.1039/D0NJ02009E},
 journal = {New Journal of Chemistry},
 number = {27}
}

Synthesis, crystal structures and antibacterial activities of new Pt( ii ) complexes with adamantane derivatives are presented in this article.

@article{
 title = {Silver(I) and gold(I) complexes with sulfasalazine: Spectroscopic characterization, theoretical studies and antiproliferative activities over Gram-positive and Gram-negative bacterial strains},
 type = {article},
 year = {2020},
 pages = {128158},
 volume = {1214},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S002228602030483X},
 month = {8},
 id = {a548ddf9-933e-3386-b14d-7128b5074e5f},
 created = {2020-07-23T00:23:11.863Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2020-07-23T00:23:11.863Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Fiori-Duarte, Ana Thereza and de Paiva, Raphael Enoque F. and Manzano, Carlos M. and Lustri, Wilton R. and Corbi, Pedro P.},
 doi = {10.1016/j.molstruc.2020.128158},
 journal = {Journal of Molecular Structure}
}

@article{
 title = {Synthesis, characterization, crystal structure and in vitro antiproliferative assays of the 2-thiouracilato(triphenylphosphine)gold(I) complex},
 type = {article},
 year = {2019},
 pages = {169-178},
 volume = {1178},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S0022286018312092},
 month = {2},
 id = {d778b695-b8f0-34fb-b396-320ed6674924},
 created = {2018-10-26T19:26:49.333Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T19:26:49.333Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Bormio Nunes, Julia H. and Simoni, Deborah A. and Braga, Lúcia E.O. and Ruiz, Ana Lúcia T.G. and Ernesto de Carvalho, João and Corbi, Pedro P.},
 doi = {10.1016/j.molstruc.2018.10.026},
 journal = {Journal of Molecular Structure}
}

@article{
 title = {Polynuclear copper(II) complexes with nalidixic acid hydrazones: Antiproliferative activity and selectivity assessment over a panel of tumor cells},
 type = {article},
 year = {2019},
 pages = {491-502},
 volume = {484},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S0020169318307072},
 month = {1},
 id = {6bc9cbf6-146d-3994-bf14-94a41f61eff5},
 created = {2019-08-03T16:48:14.629Z},
 file_attached = {false},
 profile_id = {6d4e9e22-09e3-3340-83ee-25b0de1090e1},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2019-08-03T16:48:14.629Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Bergamini, Fernando R.G. and Nunes, Julia H.B. and de Carvalho, Marcos A. and Ribeiro, Marcos A. and de Paiva, Paula P. and Banzato, Thais P. and Ruiz, Ana L.T.G. and de Carvalho, João E. and Lustri, Wilton R. and Martins, Daniel O.T.A. and da Costa Ferreira, Ana M. and Corbi, Pedro P.},
 doi = {10.1016/j.ica.2018.09.084},
 journal = {Inorganica Chimica Acta}
}

@article{
 title = {A new palladium(II) complex with ibuprofen: Spectroscopic characterization, DFT studies, antibacterial activities and interaction with biomolecules},
 type = {article},
 year = {2019},
 pages = {144-154},
 volume = {1186},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S0022286019302819},
 month = {6},
 id = {59b1ec9b-cb26-349d-ab3d-6e8edb087955},
 created = {2019-08-03T16:48:14.861Z},
 file_attached = {false},
 profile_id = {6d4e9e22-09e3-3340-83ee-25b0de1090e1},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2019-08-03T16:48:14.861Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Fiori-Duarte, Ana Thereza and Bergamini, Fernando R.G. and de Paiva, Raphael Enoque F. and Manzano, Carlos M. and Lustri, Wilton R. and Corbi, Pedro P.},
 doi = {10.1016/j.molstruc.2019.03.020},
 journal = {Journal of Molecular Structure}
}

@article{
 title = {New findings on the antiproliferative activity of the silver(I) complex with 5-fluorouracil against human multi-resistant NCI/ADR-RES ovarian tumor cells},
 type = {article},
 year = {2019},
 pages = {359-368},
 volume = {60},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S0887233319303522},
 month = {10},
 id = {65c67799-7f98-3782-b07b-f3a833c56961},
 created = {2020-07-23T00:23:11.350Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2020-07-23T00:23:11.350Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Bormio Nunes, Julia H. and de Paiva, Paula P. and Ruiz, Ana Lúcia T.G. and de Carvalho, João Ernesto and Corbi, Pedro P.},
 doi = {10.1016/j.tiv.2019.06.018},
 journal = {Toxicology in Vitro}
}

@article{
 title = {Polynuclear copper(II) complexes with nalidixic acid hydrazones: Antiproliferative activity and selectivity assessment over a panel of tumor cells},
 type = {article},
 year = {2019},
 pages = {491-502},
 volume = {484},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S0020169318307072},
 month = {1},
 id = {25afa8f9-6234-3b54-8546-99ec4e0f71c4},
 created = {2020-07-23T00:23:11.588Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2020-07-23T00:23:11.588Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Bergamini, Fernando R.G. and Nunes, Julia H.B. and de Carvalho, Marcos A. and Ribeiro, Marcos A. and de Paiva, Paula P. and Banzato, Thais P. and Ruiz, Ana L.T.G. and de Carvalho, João E. and Lustri, Wilton R. and Martins, Daniel O.T.A. and da Costa Ferreira, Ana M. and Corbi, Pedro P.},
 doi = {10.1016/j.ica.2018.09.084},
 journal = {Inorganica Chimica Acta}
}

@article{
 title = {Synthesis, crystallographic studies, molecular modeling and in vitro biological studies of silver(I) complexes with aminoadamantane ligands},
 type = {article},
 year = {2019},
 pages = {114116},
 volume = {173},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S0277538719305467},
 month = {11},
 id = {b1c3cb05-a8a3-3671-a0df-ca4fc0a16a48},
 created = {2020-07-23T00:23:55.713Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2020-07-23T00:23:55.713Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {dos Santos Pereira, Anna Karla and Nakahata, Douglas Hideki and Manzano, Carlos Marrote and de Alencar Simoni, Déborah and Pereira, Douglas Henrique and Lustri, Wilton Rogério and Formiga, André Luiz Barboza and Corbi, Pedro Paulo},
 doi = {10.1016/j.poly.2019.114116},
 journal = {Polyhedron}
}

@article{
 title = {Pt(II) and Pd(II) complexes with ibuprofen hydrazide: Characterization, theoretical calculations, antibacterial and antitumor assays and studies of interaction with CT-DNA},
 type = {article},
 year = {2018},
 keywords = {Antiproliferative assays,DFT studies,Ibuprofen hydrazide,Palladium(II),Platinum(II),Spectroscopic analysis},
 pages = {469-479},
 volume = {1154},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0022286017314187,https://linkinghub.elsevier.com/retrieve/pii/S0022286017314187},
 month = {2},
 id = {c966b3ca-5471-3867-b757-3a9a3473b5c8},
 created = {2017-11-11T01:47:42.475Z},
 file_attached = {false},
 profile_id = {6d4e9e22-09e3-3340-83ee-25b0de1090e1},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T19:26:49.902Z},
 read = {false},
 starred = {false},
 authored = {true},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {a b s t r a c t Palladium(II) and platinum(II) complexes with a hydrazide derivative of ibuprofen (named HIB) were synthesized and characterized by chemical and spectroscopic methods. Elemental and thermogravi-metric analyses, as well as ESI-QTOF-MS studies for both complexes, confirmed a 1:2:2 metal/HIB/Cl À molar ratio. The crystal structure of the palladium(II) complex was solved by single crystal X-ray diffractometric analysis, which permitted identifying the coordination formula [PdCl 2 (HIB) 2 ]. Crystallo-graphic studies also indicate coordination of HIB to the metal by the NH 2 group. Nuclear magnetic resonance and infrared spectroscopies reinforced the coordination observed in the crystal structure and suggested that the platinum(II) complex presents similar coordination modes and structure when compared with the Pd(II) complex. The complexes had their structures optimized with the aid of DFT methods. In vitro antiproliferative assays showed that the [PdCl 2 (HIB) 2 ] complex is active over ovarian cancer cell line OVCAR-03, while biophysical studies indicated its capacity to interact with CT-DNA. The complexes were inactive over Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa bac-terial strains.},
 bibtype = {article},
 author = {Manzano, Carlos M and Bergamini, Fernando RG and Lustri, Wilton R and Ruiz, Ana Lúcia T.G. and de Oliveira, Ellen CS and Ribeiro, Marcos A and Formiga, André LB and Corbi, Pedro P},
 doi = {10.1016/j.molstruc.2017.10.072},
 journal = {Journal of Molecular Structure}
}

a b s t r a c t Palladium(II) and platinum(II) complexes with a hydrazide derivative of ibuprofen (named HIB) were synthesized and characterized by chemical and spectroscopic methods. Elemental and thermogravi-metric analyses, as well as ESI-QTOF-MS studies for both complexes, confirmed a 1:2:2 metal/HIB/Cl À molar ratio. The crystal structure of the palladium(II) complex was solved by single crystal X-ray diffractometric analysis, which permitted identifying the coordination formula [PdCl 2 (HIB) 2 ]. Crystallo-graphic studies also indicate coordination of HIB to the metal by the NH 2 group. Nuclear magnetic resonance and infrared spectroscopies reinforced the coordination observed in the crystal structure and suggested that the platinum(II) complex presents similar coordination modes and structure when compared with the Pd(II) complex. The complexes had their structures optimized with the aid of DFT methods. In vitro antiproliferative assays showed that the [PdCl 2 (HIB) 2 ] complex is active over ovarian cancer cell line OVCAR-03, while biophysical studies indicated its capacity to interact with CT-DNA. The complexes were inactive over Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa bac-terial strains.

@article{
 title = {Gold-Catalyzed C-S Aryl-Group Transfer in Zinc Finger Proteins},
 type = {article},
 year = {2018},
 keywords = {Cysteine Arylation,S transfer,Zinc Finger Proteins: Au,catalyzed C},
 pages = {9305-9309},
 volume = {57},
 websites = {http://doi.wiley.com/10.1002/anie.201803082},
 month = {7},
 publisher = {Wiley-Blackwell},
 day = {20},
 id = {c3fe1b3b-908e-3cbe-916d-f3e3c30c266e},
 created = {2018-06-14T02:50:07.191Z},
 accessed = {2018-06-13},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-24T13:39:28.800Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {de Paiva, Raphael E. F. and Du, Zhifeng and Nakahata, Douglas H. and Lima, Frederico A. and Corbi, Pedro P. and Farrell, Nicholas P.},
 doi = {10.1002/anie.201803082},
 journal = {Angewandte Chemie International Edition},
 number = {30}
}

@article{
 title = {Influence of chemical and physical conditions in selection of Gluconacetobacter hansenii ATCC 23769 strains with high capacity to produce bacterial cellulose for application as sustained antimicrobial drug-release supports},
 type = {article},
 year = {2018},
 pages = {777-791},
 volume = {125},
 websites = {http://doi.wiley.com/10.1111/jam.13916},
 month = {9},
 id = {31bd42a9-bd16-3038-a270-1227086f15cf},
 created = {2018-10-26T19:26:49.508Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T19:26:49.508Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Lazarini, S.C. and Yamada, C. and Barud, H.S. and Trovatti, E. and Corbi, P.P. and Lustri, W.R.},
 doi = {10.1111/jam.13916},
 journal = {Journal of Applied Microbiology},
 number = {3}
}

@article{
 title = {The nitro-reduced metabolite of nimesulide: Crystal structure, spectroscopic characterization, ESI-QTOF mass spectrometric analysis and antibacterial evaluation},
 type = {article},
 year = {2018},
 pages = {469-475},
 volume = {1157},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S0022286017317052},
 month = {4},
 id = {41094670-b3b4-3e8e-bdb0-6b44201ed1b0},
 created = {2018-10-26T20:17:54.799Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T20:17:54.799Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Nunes, Julia H.B. and Nakahata, Douglas H. and Lustri, Wilton R. and Corbi, Pedro P. and de Paiva, Raphael E.F.},
 doi = {10.1016/j.molstruc.2017.12.085},
 journal = {Journal of Molecular Structure}
}

@article{
 title = {A Silver Complex with Cycloserine: Synthesis, Spectroscopic Characterization, Crystal Structure and In Vitro Biological Studies},
 type = {article},
 year = {2018},
 pages = {1719-1726},
 volume = {3},
 websites = {http://doi.wiley.com/10.1002/slct.201703078},
 month = {2},
 day = {14},
 id = {c8081291-5b59-3bbe-8945-57c796dfc6b6},
 created = {2018-10-26T20:17:54.985Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T20:17:54.985Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Ciol, Mariana Rosolen and Manzano, Carlos Marrote and Cuin, Alexandre and Pavan, Fernando Rogério and Ribeiro, Camila Maríngolo and Ruiz, Ana Lúcia Tasca Gois and de Oliveira, Ellen Cristina S. and Lustri, Wilton Rogério and Fregonezi, Nathália Ferreira and Nogueira, Flávia Aparecida Resende and Corbi, Pedro P.},
 doi = {10.1002/slct.201703078},
 journal = {ChemistrySelect},
 number = {6}
}

@article{
 title = {Sulfonamide-containing copper(II) metallonucleases: Correlations with in vitro antimycobacterial and antiproliferative activities},
 type = {article},
 year = {2018},
 pages = {85-96},
 volume = {187},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S0162013418301727},
 month = {10},
 id = {175f0697-b71d-3180-979e-bb9bed7670d4},
 created = {2018-10-26T20:17:54.987Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T20:17:54.987Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Nakahata, Douglas H. and de Paiva, Raphael E.F. and Lustri, Wilton R. and Ribeiro, Camila M. and Pavan, Fernando R. and da Silva, Gisele G. and Ruiz, Ana L.T.G. and de Carvalho, João E. and Corbi, Pedro P.},
 doi = {10.1016/j.jinorgbio.2018.07.011},
 journal = {Journal of Inorganic Biochemistry}
}

@article{
 title = {X-ray Absorption Spectroscopy Combined with Time-Dependent Density Functional Theory Elucidates Differential Substitution Pathways of Au(I) and Au(III) with Zinc Fingers},
 type = {article},
 year = {2018},
 pages = {218-230},
 volume = {57},
 websites = {http://pubs.acs.org/doi/10.1021/acs.inorgchem.7b02406},
 month = {1},
 day = {2},
 id = {1acc72e4-97d2-3b1a-a0e4-2ae2c08e245c},
 created = {2018-10-26T20:17:54.992Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T20:17:54.992Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Abbehausen, Camilla and de Paiva, Raphael Enoque Ferraz and Bjornsson, Ragnar and Gomes, Saulo Quintana and Du, Zhifeng and Corbi, Pedro Paulo and Lima, Frederico Alves and Farrell, Nicholas},
 doi = {10.1021/acs.inorgchem.7b02406},
 journal = {Inorganic Chemistry},
 number = {1}
}

@article{
 title = {Silver(I) and zinc(II) complexes with symmetrical cinnamaldehyde Schiff base derivative: Spectroscopic, powder diffraction characterization, and antimycobacterial studies},
 type = {article},
 year = {2018},
 pages = {166-171},
 volume = {146},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S0277538718301086},
 month = {5},
 id = {4b7d52b0-017e-3d2e-bd64-0ada4c220895},
 created = {2018-10-26T20:24:31.786Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T20:24:31.786Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Amaral, Thaeny C. and Miguel, Fábio B. and Couri, Mara R.C. and Corbi, Pedro P. and Carvalho, Marcos A. and Campos, Débora L. and Pavan, Fernando R. and Cuin, Alexandre},
 doi = {10.1016/j.poly.2018.02.024},
 journal = {Polyhedron}
}

@article{
 title = {Synthesis, characterization and in vitro biological assays of a silver(I) complex with 5-fluorouracil: A strategy to overcome multidrug resistant tumor cells},
 type = {article},
 year = {2017},
 pages = {93-101},
 volume = {195},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0022113916304894},
 month = {3},
 id = {d3d6ee77-39cc-342e-90da-e264af62aa08},
 created = {2017-03-24T14:12:23.635Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:23.635Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Nunes, Julia H. Bormio and Bergamini, Fernando R.G. and Lustri, Wilton R. and de Paiva, Paula P. and Ruiz, Ana Lúcia T.G. and de Carvalho, João Ernesto and Corbi, Pedro P.},
 doi = {10.1016/j.jfluchem.2017.01.016},
 journal = {Journal of Fluorine Chemistry}
}

@article{
 title = {Synthesis, crystallographic studies, high resolution mass spectrometric analyses and antibacterial assays of silver(I) complexes with sulfisoxazole and sulfadimethoxine},
 type = {article},
 year = {2017},
 pages = {172-179},
 volume = {121},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0277538716304764},
 month = {1},
 id = {4d170918-a83c-36da-afea-264825db936a},
 created = {2017-03-24T14:12:23.719Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:23.719Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Fiori, Ana Thereza M. and Nakahata, Douglas H. and Cuin, Alexandre and Lustri, Wilton R. and Corbi, Pedro P.},
 doi = {10.1016/j.poly.2016.09.046},
 journal = {Polyhedron}
}

@article{
 title = {Synthesis, characterization and preliminary antimicrobial assays of copper(II) complexes with 2-(imidazole-2-yl)heteroaryl ligands},
 type = {article},
 year = {2017},
 pages = {224-232},
 volume = {458},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0020169317300695},
 month = {3},
 id = {a6c9619c-1801-3137-a865-3e6728f83825},
 created = {2017-03-24T14:12:25.185Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:53:27.349Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Nakahata, Douglas H. and Ribeiro, Marcos A. and Corbi, Pedro P. and Machado, Daisy and Lancellotti, Marcelo and Lustri, Wilton R. and da Costa Ferreira, Ana M. and Formiga, André L.B.},
 doi = {10.1016/j.ica.2017.01.015},
 journal = {Inorganica Chimica Acta}
}

@article{
 title = {Spectroscopic characterization and biological studies in vitro of a new silver complex with furosemide: Prospective of application as an antimicrobial agent},
 type = {article},
 year = {2017},
 pages = {386-394},
 volume = {1134},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0022286016313758},
 month = {4},
 id = {c905884d-7902-3fdf-a189-a9a531323f86},
 created = {2017-03-24T14:12:25.427Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:25.427Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Lustri, Wilton R. and Lazarini, Silmara C. and Lustri, Bruna Cardinali and Corbi, Pedro P. and Silva, Maria Aline C. and Resende Nogueira, Flávia Aparecida and Aquino, Renata and Amaral, André C. and Treu Filho, Oswaldo and Massabni, Antonio Carlos and da Silva Barud, Hernane},
 doi = {10.1016/j.molstruc.2016.12.056},
 journal = {Journal of Molecular Structure}
}

@article{
 title = {Synthesis and crystal structure of dichlorido(1,10-phenanthroline-κ 2 N , N ′)gold(III) hexafluoridophosphate},
 type = {article},
 year = {2017},
 pages = {1048-1051},
 volume = {73},
 websites = {http://scripts.iucr.org/cgi-bin/paper?S2056989017008763},
 month = {7},
 day = {1},
 id = {e1a4dabf-88af-3bc3-9d82-31def74b2777},
 created = {2017-06-20T20:42:05.216Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-06-20T20:42:05.216Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 abstract = {A gold(III) salt of composition [AuCl 2 (C 12 H 8 N 2 )]PF 6 was prepared and characterized by elemental and mass spectrometric analysis (ESI(+)–QTOF–MS), 1 H nuclear magnetic resonance measurements and by single-crystal X-ray diffraction. The square-planar coordination sphere of Au III comprises the bidentate 1,10-phenanthroline ligand and two chloride ions, with the Au III ion only slightly shifted from the least-squares plane of the ligating atoms (r.m.s. = 0.018 Å). In contrast to two other previously reported Au III -phenantroline structures that are stabilized by interactions involving the chlorido ligands, the packing of the title compound does not present these features. Instead, the hexafluoridophosphate counter-ion gives rise to anion...π interactions that are a crucial factor for the crystal packing.},
 bibtype = {article},
 author = {Ferraz de Paiva, Raphael Enoque and Nakahata, Douglas Hideki and Corbi, Pedro Paulo},
 doi = {10.1107/S2056989017008763},
 journal = {Acta Crystallographica Section E Crystallographic Communications},
 number = {7}
}

A gold(III) salt of composition [AuCl 2 (C 12 H 8 N 2 )]PF 6 was prepared and characterized by elemental and mass spectrometric analysis (ESI(+)–QTOF–MS), 1 H nuclear magnetic resonance measurements and by single-crystal X-ray diffraction. The square-planar coordination sphere of Au III comprises the bidentate 1,10-phenanthroline ligand and two chloride ions, with the Au III ion only slightly shifted from the least-squares plane of the ligating atoms (r.m.s. = 0.018 Å). In contrast to two other previously reported Au III -phenantroline structures that are stabilized by interactions involving the chlorido ligands, the packing of the title compound does not present these features. Instead, the hexafluoridophosphate counter-ion gives rise to anion...π interactions that are a crucial factor for the crystal packing.

@article{
 title = {N , N ′, N ′′ versus N , N ′, O imine-containing coordination motifs: ligand-directed synthesis of mononuclear and binuclear Cu II compounds},
 type = {article},
 year = {2017},
 pages = {1563-1567},
 volume = {73},
 websites = {http://scripts.iucr.org/cgi-bin/paper?S2056989017013652},
 month = {10},
 day = {1},
 id = {28bf8292-4c26-3593-b953-f36290eb18ef},
 created = {2018-10-26T19:26:48.801Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T19:26:48.801Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 abstract = {It is demonstrated here that tridentate imine ligands can control the nuclearity of copper(II) complexes based on the donor atoms present in the ligand. The N , N ′, N ′′-donating imine ligand led to a mononuclear compound, namely dichlorido[ N , N -dimethyl- N ′-(pyridin-2-ylmethylidene)ethane-1,2-diamine]copper(II) monohydrate, [CuCl 2 (C 10 H 15 N 3 )]·H 2 O, 1 , while the N , N ′, O -donating imine ligand produced a binuclear metal complex, namely μ 2 -chlorido-dichlorido(μ 2 -2-[2-(dimethylamino)ethyl]iminomethylphenolato)( N , N -dimethylethylenediamine)dicopper(II) 0.11-hydrate, [Cu 2 (C 11 H 15 N 2 O)Cl 3 (C 4 H 12 N 2 )]·0.11H 2 O, 2 . The structure of 2 is a remarkable example of a binuclear copper(II) complex containing a single substituted 2-iminomethylphenolate ligand that has two copper(II) sites in square-pyramidal coordination.},
 bibtype = {article},
 author = {Ferraz de Paiva, Raphael Enoque and Nakahata, Douglas Hideki and Carvalho, Marcos Alberto de and Rodrigues Goulart Bergamini, Fernando and Corbi, Pedro Paulo},
 doi = {10.1107/S2056989017013652},
 journal = {Acta Crystallographica Section E Crystallographic Communications},
 number = {10}
}

It is demonstrated here that tridentate imine ligands can control the nuclearity of copper(II) complexes based on the donor atoms present in the ligand. The N , N ′, N ′′-donating imine ligand led to a mononuclear compound, namely dichlorido[ N , N -dimethyl- N ′-(pyridin-2-ylmethylidene)ethane-1,2-diamine]copper(II) monohydrate, [CuCl 2 (C 10 H 15 N 3 )]·H 2 O, 1 , while the N , N ′, O -donating imine ligand produced a binuclear metal complex, namely μ 2 -chlorido-dichlorido(μ 2 -2-[2-(dimethylamino)ethyl]iminomethylphenolato)( N , N -dimethylethylenediamine)dicopper(II) 0.11-hydrate, [Cu 2 (C 11 H 15 N 2 O)Cl 3 (C 4 H 12 N 2 )]·0.11H 2 O, 2 . The structure of 2 is a remarkable example of a binuclear copper(II) complex containing a single substituted 2-iminomethylphenolate ligand that has two copper(II) sites in square-pyramidal coordination.

@article{
 title = {Copper(II) and silver(I) complexes with sulfamethizole: synthesis, spectroscopic characterization, ESI-QTOF mass spectrometric analysis, crystal structure and antibacterial activities},
 type = {article},
 year = {2017},
 pages = {168-176},
 volume = {138},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S0277538717306113},
 month = {12},
 id = {dedc309e-f9c1-3779-8ac1-ebe964f023b0},
 created = {2018-10-26T19:26:49.012Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T19:26:49.012Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Yamamoto, Lais Megumi and Nunes, Julia Helena Bormio and Ribeiro, Marcos Antônio and Ferreira, Ana Maria da Costa and Lustri, Wilton Rogério and Corbi, Pedro Paulo},
 doi = {10.1016/j.poly.2017.09.034},
 journal = {Polyhedron}
}

@article{
 title = {Probing the HIV-1 NCp7 Nucleocapsid Protein with Site-Specific Gold(I)–Phosphine Complexes},
 type = {article},
 year = {2017},
 pages = {12308-12318},
 volume = {56},
 websites = {http://pubs.acs.org/doi/10.1021/acs.inorgchem.7b01762},
 month = {10},
 day = {16},
 id = {3a74de3c-1e5f-3ba2-b0ec-b68f9b4b43ab},
 created = {2018-10-26T19:26:49.051Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T19:26:49.051Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {de Paiva, Raphael E. F. and Du, Zhifeng and Peterson, Erica J. and Corbi, Pedro P. and Farrell, Nicholas P.},
 doi = {10.1021/acs.inorgchem.7b01762},
 journal = {Inorganic Chemistry},
 number = {20}
}

@article{
 title = {A novel binuclear copper complex incorporating a nalidixic acid derivative displaying a one-dimensional coordination polymeric structure},
 type = {article},
 year = {2016},
 keywords = {BINUCLEAR COMPLEX,CARBONYL HYDRAZONE,COMPUTATIONAL CHEMISTRY,CRYSTAL STRUCTURE,DFT,DIMENSIONAL COPPER(II) COORDINATION POLYMER,NALIDIXIC ACID,ONE},
 pages = {544-548},
 volume = {72},
 websites = {http://scripts.iucr.org/cgi-bin/paper?S2053229616008913},
 month = {7},
 publisher = {International Union of Crystallography},
 day = {1},
 id = {29675281-0c8a-3f53-b93c-f42977670649},
 created = {2017-03-24T14:12:22.803Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-10-20T04:36:50.244Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {The identification of the antibacterial action of nalidixic acid (nx) was central to the development of the quinolone antibacterial compounds. The ability of the nx naphthyridyl ring to interact with and inhibit some proteins has encouraged the investigation of similar structures in the search for more active compounds with less adverse effects. The possibility of structural modification by attachment of other biologically active moieties to the naphthyridyl ring of nx allowed the development of new active antimicrobial molecules. Hydrazone derivatives of nx can be synthesized easily based on the condensation of the hydrazide derivative of nx with the desired aldehyde or ketone. Only a few complexes with nx hydrazone derivatives have been described but for none were the crystal structures elucidated. The synthesis of a new one-dimensional Cu II coordination polymer, namely catena -poly[[copper(II)-di-μ-chlorido-copper(II)-μ-1-ethyl- N ′-[(1 H -imidazol-4-yl)methylidene]-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazidato-[dimethanolcopper(II)]-μ-1-ethyl- N ′-[(1 H -imidazol-3-yl)methylidene]-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazidato] dichloride methanol tetrasolvate], [Cu 3 (C 16 H 15 N 6 O 2 ) 2 Cl 2 (CH 3 OH) 2 ]Cl 2 ·4CH 3 OH n , with the (1 H -imidazol-4-yl)methylidene carbohydrazide derivative of nalidixic acid (denoted h4imi), is presented and its structure is compared to the density functional theory (DFT) optimized structure of free h4imi. The title structure presents an octahedral Cu II ion on an inversion centre alternating along a polymer chain with a square-pyramidal Cu II ion, with the two Cu II centres bridged by two chloride ligands. Hydrogen bonds involving chloride counter-ions and methanol solvent molecules mediate the three-dimensional packing of the polymer. Comparison of the geometrical results from the structure analysis with those derived from a DFT study of the free ligand reveal the differences that arise upon coordination.},
 bibtype = {article},
 author = {Bergamini, F. R. G. and Ribeiro, M. A. and Miranda, P. C. M. L. and Formiga, A. L. B. and Corbi, P. P.},
 doi = {10.1107/S2053229616008913},
 journal = {Acta Crystallographica Section C Structural Chemistry},
 number = {7}
}

The identification of the antibacterial action of nalidixic acid (nx) was central to the development of the quinolone antibacterial compounds. The ability of the nx naphthyridyl ring to interact with and inhibit some proteins has encouraged the investigation of similar structures in the search for more active compounds with less adverse effects. The possibility of structural modification by attachment of other biologically active moieties to the naphthyridyl ring of nx allowed the development of new active antimicrobial molecules. Hydrazone derivatives of nx can be synthesized easily based on the condensation of the hydrazide derivative of nx with the desired aldehyde or ketone. Only a few complexes with nx hydrazone derivatives have been described but for none were the crystal structures elucidated. The synthesis of a new one-dimensional Cu II coordination polymer, namely catena -poly[[copper(II)-di-μ-chlorido-copper(II)-μ-1-ethyl- N ′-[(1 H -imidazol-4-yl)methylidene]-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazidato-[dimethanolcopper(II)]-μ-1-ethyl- N ′-[(1 H -imidazol-3-yl)methylidene]-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazidato] dichloride methanol tetrasolvate], [Cu 3 (C 16 H 15 N 6 O 2 ) 2 Cl 2 (CH 3 OH) 2 ]Cl 2 ·4CH 3 OH n , with the (1 H -imidazol-4-yl)methylidene carbohydrazide derivative of nalidixic acid (denoted h4imi), is presented and its structure is compared to the density functional theory (DFT) optimized structure of free h4imi. The title structure presents an octahedral Cu II ion on an inversion centre alternating along a polymer chain with a square-pyramidal Cu II ion, with the two Cu II centres bridged by two chloride ligands. Hydrogen bonds involving chloride counter-ions and methanol solvent molecules mediate the three-dimensional packing of the polymer. Comparison of the geometrical results from the structure analysis with those derived from a DFT study of the free ligand reveal the differences that arise upon coordination.

@article{
 title = {Crystal structure and cytotoxic activities of a bis(pyrrolyl-imine) gold(III) complex},
 type = {article},
 year = {2016},
 keywords = {DFT,DNA,Pyrrolyl-imine,cytotoxic activity,gold(III)},
 pages = {2707-2722},
 volume = {69},
 websites = {https://www.tandfonline.com/doi/full/10.1080/00958972.2016.1214949},
 month = {9},
 publisher = {Taylor & Francis},
 day = {16},
 id = {ce7dd70b-8986-3eb7-b20c-632ccdfae676},
 created = {2017-03-24T14:12:24.560Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:24.560Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {AbstractA gold(III) complex with N,N′-ethylenebis(pyrrol-2-yl-methyleneamine) (H2pyren) was synthesized and characterized by physicochemical and spectroscopic measurements. Density functional theory (DFT) studies and cytotoxic assays were performed. Infrared, mass spectrometry, and 1H, 13C, and 15N,1H nuclear magnetic resonance analyses indicate that pyren is deprotonated and gold(III) is four coordinate in a square planar environment, with the pyrrole and imine nitrogens as donors. The structure was confirmed by powder X-ray diffraction and confirmed as a minimum of the potential energy surface by DFT. Cytotoxic activity of [Au(pyren)]+ was active against three tumorigenic cell lines with IC50 values of 35 μM. Interaction studies with CT-DNA by fluorescence and competition with ethidium bromide (EB) showed a quenching of the emission band of DNA with a Stern–Volmer quenching constant value of (3.0 ± 0.1) × 104 M−1 and a decrease in fluorescence quenching of EB-DNA system, respectively, confirming that ...},
 bibtype = {article},
 author = {Profirio, Daniel De Moraes and Paiva, Raphael Enoque Ferraz De and Abbehausen, Camilla and Cuin, Alexandre and Masciocchi, Norberto and Machado, Daisy and Lancellotti, Marcelo and Corbi, Pedro Paulo and Formiga, André Luiz Barboza},
 doi = {10.1080/00958972.2016.1214949},
 journal = {Journal of Coordination Chemistry},
 number = {18}
}

AbstractA gold(III) complex with N,N′-ethylenebis(pyrrol-2-yl-methyleneamine) (H2pyren) was synthesized and characterized by physicochemical and spectroscopic measurements. Density functional theory (DFT) studies and cytotoxic assays were performed. Infrared, mass spectrometry, and 1H, 13C, and 15N,1H nuclear magnetic resonance analyses indicate that pyren is deprotonated and gold(III) is four coordinate in a square planar environment, with the pyrrole and imine nitrogens as donors. The structure was confirmed by powder X-ray diffraction and confirmed as a minimum of the potential energy surface by DFT. Cytotoxic activity of [Au(pyren)]+ was active against three tumorigenic cell lines with IC50 values of 35 μM. Interaction studies with CT-DNA by fluorescence and competition with ethidium bromide (EB) showed a quenching of the emission band of DNA with a Stern–Volmer quenching constant value of (3.0 ± 0.1) × 104 M−1 and a decrease in fluorescence quenching of EB-DNA system, respectively, confirming that ...

@article{
 title = {Characterization of bilayer bacterial cellulose membranes with different fiber densities: a promising system for controlled release of the antibiotic ceftriaxone},
 type = {article},
 year = {2016},
 pages = {737-748},
 volume = {23},
 websites = {http://link.springer.com/10.1007/s10570-015-0843-4},
 month = {2},
 publisher = {Springer Netherlands},
 day = {18},
 id = {2242e7fc-d794-34d0-bc31-8366075f5f53},
 created = {2017-03-24T14:12:24.689Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:53:26.953Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Lazarini, Silmara C. and de Aquino, Renata and Amaral, André C. and Corbi, Fabiana C. A. and Corbi, Pedro P. and Barud, Hernane S. and Lustri, Wilton R.},
 doi = {10.1007/s10570-015-0843-4},
 journal = {Cellulose},
 number = {1}
}

@article{
 title = {Copper(II), palladium(II) and platinum(II) complexes with 2,2-thiophen-yl-imidazole: Synthesis, spectroscopic characterization, X-ray crystallographic studies and interactions with calf-thymus DNA},
 type = {article},
 year = {2016},
 pages = {304-315},
 volume = {443},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0020169316000220},
 month = {3},
 id = {f21266dd-95cb-3806-974e-3d2c35636cef},
 created = {2017-03-24T14:12:24.921Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:24.921Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Zanvettor, Nina T. and Nakahata, Douglas H. and de Paiva, Raphael E.F. and Ribeiro, Marcos A. and Cuin, Alexandre and Corbi, Pedro P. and Formiga, André L.B.},
 doi = {10.1016/j.ica.2016.01.011},
 journal = {Inorganica Chimica Acta}
}

@article{
 title = {Enhanced performance of a metal-organic framework analogue to MIL-101(Cr) containing amine groups for ibuprofen and nimesulide controlled release},
 type = {article},
 year = {2016},
 pages = {47-50},
 volume = {70},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S1387700316301526},
 month = {8},
 id = {43e1056e-9ba1-387f-b64a-52fe6a642403},
 created = {2017-03-24T14:12:25.419Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:25.419Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Silva, Irlene M.P. and Carvalho, Marcos A. and Oliveira, Cintia S. and Profirio, Daniel M. and Ferreira, Ricardo B. and Corbi, Pedro P. and Formiga, André L.B.},
 doi = {10.1016/j.inoche.2016.05.020},
 journal = {Inorganic Chemistry Communications}
}

@article{
 title = {Synthesis, spectroscopic characterization, crystallographic studies and antibacterial assays of new copper(II) complexes with sulfathiazole and nimesulide},
 type = {article},
 year = {2016},
 pages = {14-20},
 volume = {1112},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0022286016301004},
 month = {5},
 id = {6776de7a-5f74-3e90-894e-fc5eb7fad0b2},
 created = {2017-03-24T14:12:25.454Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:25.454Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Nunes, Julia Helena Bormio and de Paiva, Raphael Enoque Ferraz and Cuin, Alexandre and da Costa Ferreira, Ana Maria and Lustri, Wilton Rogério and Corbi, Pedro Paulo},
 doi = {10.1016/j.molstruc.2016.02.006},
 journal = {Journal of Molecular Structure}
}

@article{
 title = {Crystal structure, spectroscopic characterization and antibacterial activities of a silver complex with sulfameter},
 type = {article},
 year = {2016},
 pages = {609-615},
 volume = {1125},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S002228601630730X},
 month = {12},
 id = {11f6e88d-e05d-3787-b325-978ee63c1a47},
 created = {2017-03-24T14:12:26.101Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:26.101Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Nakahata, Douglas H. and Lustri, Wilton R. and Cuin, Alexandre and Corbi, Pedro P.},
 doi = {10.1016/j.molstruc.2016.07.049},
 journal = {Journal of Molecular Structure}
}

@article{
 title = {Synthesis, spectroscopic characterizations, crystal structures and DFT studies of nalidixic acid carbonyl hydrazones derivatives},
 type = {article},
 year = {2016},
 pages = {115-124},
 volume = {1120},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0022286016304719},
 month = {9},
 id = {9cb6cc7b-e134-3e9a-91ce-d6262084c41a},
 created = {2017-03-24T14:12:26.429Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:26.429Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Bergamini, F.R.G. and Ribeiro, M.A. and Lancellotti, M. and Machado, D. and Miranda, P.C.M.L. and Cuin, A. and Formiga, A.L.B. and Corbi, P.P.},
 doi = {10.1016/j.molstruc.2016.05.025},
 journal = {Journal of Molecular Structure}
}

@article{
 title = {Effects of coordination mode of 2-mercaptothiazoline on reactivity of Au(I) compounds with thiols and sulfur-containing proteins},
 type = {article},
 year = {2016},
 pages = {136-145},
 volume = {165},
 websites = {https://linkinghub.elsevier.com/retrieve/pii/S0162013416301349},
 month = {12},
 id = {e40514c2-a3b8-3ada-aaa7-fd019b749e42},
 created = {2018-10-26T20:24:32.332Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T20:24:32.332Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Abbehausen, C. and Manzano, C.M. and Corbi, P.P. and Farrell, N.P.},
 doi = {10.1016/j.jinorgbio.2016.05.011},
 journal = {Journal of Inorganic Biochemistry}
}

@article{
 title = {Chemical and spectroscopic characterizations, ESI-QTOF mass spectrometric measurements and DFT studies of new complexes of palladium(II) with tryptamine and mefenamic acid},
 type = {article},
 year = {2015},
 pages = {6-13},
 volume = {1100},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0022286015301319},
 month = {11},
 id = {71349ea5-8394-3511-b91e-3e6915cf35d1},
 created = {2017-03-24T14:12:23.772Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:23.772Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Carvalho, Marcos A. and Arruda, Eduardo G.R. and Profirio, Daniel M. and Gomes, Alexandre F. and Gozzo, Fábio C. and Formiga, André L.B. and Corbi, Pedro P.},
 doi = {10.1016/j.molstruc.2015.07.020},
 journal = {Journal of Molecular Structure}
}

@article{
 title = {Silver sulfadoxinate: Synthesis, structural and spectroscopic characterizations, and preliminary antibacterial assays in vitro},
 type = {article},
 year = {2015},
 pages = {180-187},
 volume = {1082},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0022286014011107},
 month = {2},
 id = {7ab4ae19-3464-32fa-8af6-bdc373d7a404},
 created = {2017-03-24T14:12:24.026Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:24.026Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Zanvettor, Nina T. and Abbehausen, Camilla and Lustri, Wilton R. and Cuin, Alexandre and Masciocchi, Norberto and Corbi, Pedro P.},
 doi = {10.1016/j.molstruc.2014.11.004},
 journal = {Journal of Molecular Structure}
}

@article{
 title = {Silver complexes with sulfathiazole and sulfamethoxazole: Synthesis, spectroscopic characterization, crystal structure and antibacterial assays},
 type = {article},
 year = {2015},
 keywords = {Antibacterial agents,Silver,Sulfamethoxazole,Sulfathiazole,X-ray diffraction},
 pages = {437-444},
 volume = {85},
 websites = {http://dx.doi.org/10.1016/j.poly.2014.09.010,http://linkinghub.elsevier.com/retrieve/pii/S0277538714006135},
 month = {1},
 publisher = {Elsevier BV},
 day = {31},
 id = {a467a37d-0b79-3260-b847-0f628e138d52},
 created = {2017-03-24T14:12:26.397Z},
 accessed = {2016-10-19},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:55:01.802Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 source_type = {JOUR},
 private_publication = {false},
 abstract = {The present work describes the synthesis and spectroscopic characterization of two silver(I) complexes with the sulfonamides sulfathiazole (AgC9H8N3O2S2, Ag-SFT) and sulfamethoxazole (AgC10H10N3O3S, Ag-SFM). Elemental analyses indicate a 1:1 metal/ligand composition for both complexes. Spectroscopic techniques such as 1H, 15N NMR and IR evidence the coordination of both ligands to silver through the nitrogen atom of the sulfonamide group, and also indicate the participation of the 5-membered N-heterocyclic ring in the coordination. The Ag-SFT crystal structure was solved by X-ray powder diffraction and indicates the formation of a dimeric structure with silver bridging between two ligand molecules. Biological studies showed the antibacterial activity of Ag-SFT and Ag-SFM complexes against Gram-positive and Gram-negative bacterial strains, with MIC values ranging from 3.45 to 6.90 mmol L-1 for the sulfathiazole complex and 1.74 to 13.9 mmol L-1 for the sulfamethoxazole complex. The complexes have shown to be more active against Gram-negative bacterial strains.},
 bibtype = {article},
 author = {Bormio Nunes, Julia Helena and de Paiva, Raphael Enoque Ferraz and Cuin, Alexandre and Lustri, Wilton Rogério and Corbi, Pedro Paulo},
 doi = {10.1016/j.poly.2014.09.010},
 journal = {Polyhedron}
}

The present work describes the synthesis and spectroscopic characterization of two silver(I) complexes with the sulfonamides sulfathiazole (AgC9H8N3O2S2, Ag-SFT) and sulfamethoxazole (AgC10H10N3O3S, Ag-SFM). Elemental analyses indicate a 1:1 metal/ligand composition for both complexes. Spectroscopic techniques such as 1H, 15N NMR and IR evidence the coordination of both ligands to silver through the nitrogen atom of the sulfonamide group, and also indicate the participation of the 5-membered N-heterocyclic ring in the coordination. The Ag-SFT crystal structure was solved by X-ray powder diffraction and indicates the formation of a dimeric structure with silver bridging between two ligand molecules. Biological studies showed the antibacterial activity of Ag-SFT and Ag-SFM complexes against Gram-positive and Gram-negative bacterial strains, with MIC values ranging from 3.45 to 6.90 mmol L-1 for the sulfathiazole complex and 1.74 to 13.9 mmol L-1 for the sulfamethoxazole complex. The complexes have shown to be more active against Gram-negative bacterial strains.

@article{
 title = {Spectroscopic characterization and molecular modeling of novel palladium(II) complexes with carbazates and hydrazides},
 type = {article},
 year = {2015},
 pages = {15-22},
 volume = {1097},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0022286015004135},
 month = {10},
 id = {fa243d5d-f1c2-30b1-9acf-971243021750},
 created = {2017-03-24T14:12:26.546Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:26.546Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Sousa, L.M. and Corbi, P.P. and Formiga, A.L.B. and Lancellotti, Marcelo and Marzano, I.M. and Pereira-Maia, E.C. and Von Poelhsitz, G. and Guerra, W.},
 doi = {10.1016/j.molstruc.2015.05.012},
 journal = {Journal of Molecular Structure}
}

@article{
 title = {Synthesis and crystal structure of a palladium(II) complex with the amino acid L-citrulline},
 type = {article},
 year = {2015},
 keywords = {amino acids,palladium complex,powder diffraction,x-ray},
 pages = {357-361},
 volume = {30},
 websites = {http://www.journals.cambridge.org/abstract_S0885715615000652},
 month = {12},
 day = {2},
 id = {a41ff4dd-75ff-3f9b-b673-132e01f48b89},
 created = {2017-04-06T15:17:13.868Z},
 file_attached = {false},
 profile_id = {6d4e9e22-09e3-3340-83ee-25b0de1090e1},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:54:59.216Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {Synthesis and structural characterization of a novel palladium Pd(II) complex with the amino acid L-citrulline (Cit, C 6 H 13 N 3 O 3 ) are presented in this paper. Elemental analysis indicates a 1:2 metal/ligand molar composition for the complex, with the molecular formula PdC 12 H 24 N 6 O 6. The compound was also characterized by infrared (IR) spectroscopic measurements and the crystal structure has been solved by powder X-ray diffraction data with simulated annealing strategy in real space. The Pd(II) complex crystallizes in the triclinic system with space group P-1 and cell parameters a = 4.6493(4) Å, b = 5.222(4) Å, c = 18.040(2) Å, α = 77.41(6)°, β = 94.72(7),° and γ = 101.45(7)°. The crystal structure confirms the presence of Pd(II) ions in a nearly square planar environment and the molecular formula with deprotonated citrulline as proposed by analytical and spectroscopic data.},
 bibtype = {article},
 author = {Mascaliovas, Bruno Z and Bergamini, Fernando R.G. and Cuin, Alexandre and Corbi, Pedro P},
 doi = {10.1017/S0885715615000652},
 journal = {Powder Diffraction},
 number = {04}
}

Synthesis and structural characterization of a novel palladium Pd(II) complex with the amino acid L-citrulline (Cit, C 6 H 13 N 3 O 3 ) are presented in this paper. Elemental analysis indicates a 1:2 metal/ligand molar composition for the complex, with the molecular formula PdC 12 H 24 N 6 O 6. The compound was also characterized by infrared (IR) spectroscopic measurements and the crystal structure has been solved by powder X-ray diffraction data with simulated annealing strategy in real space. The Pd(II) complex crystallizes in the triclinic system with space group P-1 and cell parameters a = 4.6493(4) Å, b = 5.222(4) Å, c = 18.040(2) Å, α = 77.41(6)°, β = 94.72(7),° and γ = 101.45(7)°. The crystal structure confirms the presence of Pd(II) ions in a nearly square planar environment and the molecular formula with deprotonated citrulline as proposed by analytical and spectroscopic data.

@article{
 title = {A new platinum complex with tryptophan: Synthesis, structural characterization, DFT studies and biological assays in vitro over human tumorigenic cells},
 type = {article},
 year = {2014},
 pages = {209-215},
 volume = {122},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S1386142513013619},
 month = {3},
 id = {ae348dad-3a44-3bce-8c1d-66210e33f065},
 created = {2017-03-24T14:12:23.260Z},
 accessed = {2016-10-19},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:53:26.562Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 abstract = {A new platinum(II) complex with the amino acid L-tryptophan (trp), named Pt-trp, was synthesized and characterized. Elemental, thermogravimetric and ESI-QTOF mass spectrometric analyses led to the composition [Pt(C11H11N2O2)2]⋅6H2O. Infrared spectroscopic data indicate the coordination of trp to Pt(II) through the oxygen of the carboxylate group and also through the nitrogen atom of the amino group. The 13C CP/MAS NMR spectroscopic data confirm coordination through the oxygen atom of the carboxylate group, while the 15N CP/MAS NMR data confirm coordination of the nitrogen of the NH2 group to the metal. Density functional theory (DFT) studies were applied to evaluate the cis and trans coordination modes of trp to platinum(II). The trans isomer was shown to be energetically more stable than the cis one. The Pt-trp complex was evaluated as a cytotoxic agent against SK-Mel 103 (human melanoma) and Panc-1 (human pancreatic carcinoma) cell lines. The complex was shown to be cytotoxic over the considered cells.},
 bibtype = {article},
 author = {Carvalho, Marcos A. and Shishido, Silvia M. and Souza, Bárbara C. and de Paiva, Raphael E.F. and Gomes, Alexandre F. and Gozzo, Fábio C. and Formiga, André L.B. and Corbi, Pedro P.},
 doi = {10.1016/j.saa.2013.11.044},
 journal = {Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy}
}

A new platinum(II) complex with the amino acid L-tryptophan (trp), named Pt-trp, was synthesized and characterized. Elemental, thermogravimetric and ESI-QTOF mass spectrometric analyses led to the composition [Pt(C11H11N2O2)2]⋅6H2O. Infrared spectroscopic data indicate the coordination of trp to Pt(II) through the oxygen of the carboxylate group and also through the nitrogen atom of the amino group. The 13C CP/MAS NMR spectroscopic data confirm coordination through the oxygen atom of the carboxylate group, while the 15N CP/MAS NMR data confirm coordination of the nitrogen of the NH2 group to the metal. Density functional theory (DFT) studies were applied to evaluate the cis and trans coordination modes of trp to platinum(II). The trans isomer was shown to be energetically more stable than the cis one. The Pt-trp complex was evaluated as a cytotoxic agent against SK-Mel 103 (human melanoma) and Panc-1 (human pancreatic carcinoma) cell lines. The complex was shown to be cytotoxic over the considered cells.

@article{
 title = {Investigating the inclusion of the Ag(I)-nimesulide complex into β-cyclodextrin: studies in solution and in the solid state},
 type = {article},
 year = {2014},
 pages = {225-235},
 volume = {79},
 websites = {http://link.springer.com/10.1007/s10847-013-0348-4},
 month = {6},
 publisher = {Springer Netherlands},
 day = {23},
 id = {f40977a4-9a68-3a0b-9281-7fc5b831e86a},
 created = {2017-03-24T14:12:24.271Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:53:26.558Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {de Paiva, Raphael E. F. and Abbehausen, Camilla and Bergamini, Fernando R. G. and Thompson, Andre L. and Alves, Danilo A. and Lancellotti, Marcelo and Corbi, Pedro P.},
 doi = {10.1007/s10847-013-0348-4},
 journal = {Journal of Inclusion Phenomena and Macrocyclic Chemistry},
 number = {1-2}
}

@article{
 title = {Three new mononuclear group 12 complexes with benzimidazole},
 type = {article},
 year = {2014},
 keywords = {1-Benzyl-2-phenyl-1H-benzimidazole,Cadmium,Mercury,Powder diffraction,Zinc},
 pages = {1380-1391},
 volume = {67},
 websites = {http://www.tandfonline.com/doi/abs/10.1080/00958972.2014.914179},
 month = {4},
 publisher = {Taylor & Francis},
 day = {18},
 id = {0ec633c1-f107-3855-84c1-16df2847af0b},
 created = {2017-03-24T14:12:25.713Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:25.713Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {Three iso-structural Zn(II), Cd(II), and Hg(II) complexes with 1-benzyl-2-phenyl-1H-benzimidazole (BPB), ZnBPB, CdBPB, and HgBPB, respectively, were synthesized by reaction of the ligand with the corresponding metal chlorides in methanolic solutions. The complexes [MCl2(BPB)2], where M = Zn(II), Cd(II), or Hg(II), were characterized by elemental analysis, 13C, 1H, and [1H–15N] heteronuclear multiple bond coherence NMR measurements, and Raman spectroscopy. The structures of the cadmium and mercury complexes were solved by single-crystal X-ray diffraction, while the structure of the zinc complex was determined by X-ray powder diffraction. The three compounds crystallize in the triclinic system in P-1 space group with the metal ions lying in a distorted tetrahedral environment. The zinc complex shows high luminescence in the solid state at room temperature.},
 bibtype = {article},
 author = {Amaral, Thaeny C. and De Carvalho, Gustavo S.G. and Da Silva, Adilson D. and Corbi, Pedro P. and Masciocchi, Norberto and Castellano, Eduardo E. and Cuin, Alexandre},
 doi = {10.1080/00958972.2014.914179},
 journal = {Journal of Coordination Chemistry},
 number = {8}
}

Three iso-structural Zn(II), Cd(II), and Hg(II) complexes with 1-benzyl-2-phenyl-1H-benzimidazole (BPB), ZnBPB, CdBPB, and HgBPB, respectively, were synthesized by reaction of the ligand with the corresponding metal chlorides in methanolic solutions. The complexes [MCl2(BPB)2], where M = Zn(II), Cd(II), or Hg(II), were characterized by elemental analysis, 13C, 1H, and [1H–15N] heteronuclear multiple bond coherence NMR measurements, and Raman spectroscopy. The structures of the cadmium and mercury complexes were solved by single-crystal X-ray diffraction, while the structure of the zinc complex was determined by X-ray powder diffraction. The three compounds crystallize in the triclinic system in P-1 space group with the metal ions lying in a distorted tetrahedral environment. The zinc complex shows high luminescence in the solid state at room temperature.

@article{
 title = {Synthesis, spectroscopic characterization, DFT studies, and antibacterial and antitumor activities of a novel water soluble Pd(II) complex with l-alliin},
 type = {article},
 year = {2013},
 pages = {421-426},
 volume = {1035},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0022286012011453},
 month = {3},
 id = {6e032d12-1208-3d65-a55b-5a4869a28f22},
 created = {2017-03-24T14:12:23.055Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:23.055Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Abbehausen, Camilla and Sucena, Suelen F. and Lancellotti, Marcelo and Heinrich, Tassiele A. and Abrão, Emiliana P. and Costa-Neto, Claudio M. and Formiga, André L.B. and Corbi, Pedro P.},
 doi = {10.1016/j.molstruc.2012.11.065},
 journal = {Journal of Molecular Structure}
}

@article{
 title = {A silver complex with tryptophan: Synthesis, structural characterization, DFT studies and antibacterial and antitumor assays in vitro},
 type = {article},
 year = {2013},
 keywords = {Antibacterial agent,Antitumoral assays,ESI-QTOF mass spectrometry,Silver,Solid-state NMR,l-tryptophan},
 pages = {125-131},
 volume = {1031},
 websites = {http://dx.doi.org/10.1016/j.molstruc.2012.07.044},
 month = {12},
 day = {30},
 id = {1a7fe812-e231-3eda-9b8f-6495fea03380},
 created = {2017-03-24T14:12:23.150Z},
 accessed = {2016-10-19},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:53:26.555Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 source_type = {JOUR},
 private_publication = {false},
 abstract = {The synthesis, spectroscopic characterization and biological assays of a new silver(I) complex with l-tryptophan (TRP) are presented. Elemental and thermal analyses and ESI-QTOF mass spectrometric measurements of the solid compound suggest the composition AgC11H11N 2O2. Infrared and solid-state NMR analyses indicate coordination of TRP to Ag(I) ion through the nitrogen of the NH2 group and also through the oxygen of carboxylate group. Theoretical (DFT) calculations permit proposing an optimized geometry for the complex. Antibacterial assays indicated that the Ag-TRP complex is effective against Staphylococcus aureus and Enterococcus faecalis (Gram-positive), and Pseudomonas aeruginosa and Escherichia coli (Gram-negative) bacterial strains. The complex was also cytotoxic against Panc-1 (human pancreatic carcinoma) and SK-Mel 103 (human melanoma) cells. © 2012 Elsevier B.V. All rights reserved.},
 bibtype = {article},
 author = {Carvalho, Marcos a. and de Paiva, Raphael E.F. F and Bergamini, Fernando R.G. G and Gomes, Alexandre F. and Gozzo, Fábio C. and Lustri, Wilton R. and Formiga, André L.B. B and Shishido, Silvia M. and Ferreira, Carmen V. and Corbi, Pedro P.},
 doi = {10.1016/j.molstruc.2012.07.044},
 journal = {Journal of Molecular Structure}
}

The synthesis, spectroscopic characterization and biological assays of a new silver(I) complex with l-tryptophan (TRP) are presented. Elemental and thermal analyses and ESI-QTOF mass spectrometric measurements of the solid compound suggest the composition AgC11H11N 2O2. Infrared and solid-state NMR analyses indicate coordination of TRP to Ag(I) ion through the nitrogen of the NH2 group and also through the oxygen of carboxylate group. Theoretical (DFT) calculations permit proposing an optimized geometry for the complex. Antibacterial assays indicated that the Ag-TRP complex is effective against Staphylococcus aureus and Enterococcus faecalis (Gram-positive), and Pseudomonas aeruginosa and Escherichia coli (Gram-negative) bacterial strains. The complex was also cytotoxic against Panc-1 (human pancreatic carcinoma) and SK-Mel 103 (human melanoma) cells. © 2012 Elsevier B.V. All rights reserved.

@article{
 title = {A simple method to synthesize fluorescent modified gold nanoparticles using tryptamine as the reducing and capping agent},
 type = {article},
 year = {2013},
 pages = {61-65},
 volume = {185-186},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0379677913004864},
 month = {12},
 id = {3a3fea54-9971-30f5-b8c8-04253695e490},
 created = {2017-03-24T14:12:23.812Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:23.812Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {de Carvalho, Marcos Alberto and Andrade, Patrícia Fernanda and Corbi, Fabiana Cristina Andrade and Gonçalves, Maria do Carmo and Formiga, André Luiz Barboza and Mazali, Italo Odone and Bonacin, Juliano Alves and Corbi, Pedro Paulo},
 doi = {10.1016/j.synthmet.2013.09.038},
 journal = {Synthetic Metals}
}

@article{
 title = {Gold(I)-phosphine-N-heterocycles: Biological activity and specific (ligand) interactions on the C-terminal HIVNCp7 zinc finger},
 type = {article},
 year = {2013},
 pages = {11280-11287},
 volume = {52},
 websites = {http://dx.doi.org/10.1021/ic401535s,http://pubs.acs.org/doi/pdf/10.1021/ic401535s,http://pubs.acs.org/doi/abs/10.1021/ic401535s},
 month = {10},
 publisher = {American Chemical Society},
 day = {7},
 id = {723e3eef-a6c0-3b95-ae83-819847739ab6},
 created = {2017-03-24T14:12:24.127Z},
 accessed = {2016-10-19},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:39:57.292Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 source_type = {JOUR},
 private_publication = {false},
 abstract = {The syntheses and the characterization by chemical analysis, (1)H and (31)P NMR spectroscopy, and mass spectrometry of a series of linear triphenylphosphine gold(I) complexes with substituted N-heterocycle ligands (L), [(PPh3)Au(I)(L)](+), is reported. The reaction of [(PPh3)Au(L)](+) (L = Cl(-) or substituted N- heterocyclic pyridine) with the C-terminal (Cys3His) finger of HIVNCp7 shows evidence by mass spectrometry (ESI-MS) and (31)P NMR spectroscopy of a long-lived (PPh3)Au-S-peptide species resulting from displacement of the chloride or pyridine ligand by zinc-bound cysteine with concomitant displacement of Zn(2+). In contrast, reactions with the Cys2His2 finger-3 of the Sp1 transcription factor shows significantly reduced intensities of (PPh3)Au adducts. The results suggest the possibility of systematic (electronic, steric) variations of "carrier" group PR3 and "leaving" group L as well as the nature of the zinc finger in modulation of biological activity. The cytotoxicity, cell cycle signaling effects, and cellular accumulation of the series are also reported. All compounds display cytotoxicity in the micromolar range upon 96 h continuous exposure to human tumor cells. The results may have relevance for the reported inhibition of viral load in simian virus by the gold(I) drug auranofin.},
 bibtype = {article},
 author = {Abbehausen, Camilla and Peterson, Erica J. and De Paiva, Raphael E F and Corbi, Pedro P. and Formiga, André L. B. and Qu, Yun and Farrell, Nicholas P.},
 doi = {10.1021/ic401535s},
 journal = {Inorganic Chemistry},
 number = {19}
}

The syntheses and the characterization by chemical analysis, (1)H and (31)P NMR spectroscopy, and mass spectrometry of a series of linear triphenylphosphine gold(I) complexes with substituted N-heterocycle ligands (L), [(PPh3)Au(I)(L)](+), is reported. The reaction of [(PPh3)Au(L)](+) (L = Cl(-) or substituted N- heterocyclic pyridine) with the C-terminal (Cys3His) finger of HIVNCp7 shows evidence by mass spectrometry (ESI-MS) and (31)P NMR spectroscopy of a long-lived (PPh3)Au-S-peptide species resulting from displacement of the chloride or pyridine ligand by zinc-bound cysteine with concomitant displacement of Zn(2+). In contrast, reactions with the Cys2His2 finger-3 of the Sp1 transcription factor shows significantly reduced intensities of (PPh3)Au adducts. The results suggest the possibility of systematic (electronic, steric) variations of "carrier" group PR3 and "leaving" group L as well as the nature of the zinc finger in modulation of biological activity. The cytotoxicity, cell cycle signaling effects, and cellular accumulation of the series are also reported. All compounds display cytotoxicity in the micromolar range upon 96 h continuous exposure to human tumor cells. The results may have relevance for the reported inhibition of viral load in simian virus by the gold(I) drug auranofin.

@article{
 title = {Silver(I) complexes with symmetrical Schiff bases: Synthesis, structural characterization, DFT studies and antimycobacterial assays},
 type = {article},
 year = {2013},
 pages = {104-109},
 volume = {62},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0277538713004828},
 month = {10},
 id = {361a1717-f1db-3903-bda5-204d0de0ee42},
 created = {2017-03-24T14:12:26.428Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:26.428Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Paiva, Isabela L. and de Carvalho, Gustavo S.G. and da Silva, Adilson D. and Corbi, Pedro P. and Bergamini, Fernando R.G. and Formiga, André L.B. and Diniz, Renata and do Carmo, Weberton R. and Leite, Clarice Q.F. and Pavan, Fernando R. and Cuin, Alexandre},
 doi = {10.1016/j.poly.2013.06.031},
 journal = {Polyhedron}
}

@article{
 title = {A silver complex with ibuprofen: Synthesis, solid state characterization, DFT calculations and antibacterial assays},
 type = {article},
 year = {2013},
 pages = {1-6},
 volume = {1049},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0022286013005541},
 month = {10},
 id = {83b9080c-2815-3530-be35-35ab857ea599},
 created = {2017-03-24T14:12:26.918Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:26.918Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Silva, Irlene Maria Pereira e and Profirio, Daniel de Moraes and de Paiva, Raphael Enoque Ferraz and Lancellotti, Marcelo and Formiga, André Luiz Barboza and Corbi, Pedro Paulo},
 doi = {10.1016/j.molstruc.2013.06.034},
 journal = {Journal of Molecular Structure}
}

@article{
 title = {Characterization, and crystal structure of thiophenyl-2-methylidene-2-aminophenol},
 type = {article},
 year = {2013},
 pages = {269-273},
 volume = {54},
 websites = {http://link.springer.com/10.1134/S0022476613010423},
 month = {2},
 day = {26},
 id = {4d6b7948-691b-3d55-8ec0-07e6fbdb3f4c},
 created = {2018-10-26T20:24:32.054Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T20:24:32.054Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Cuin, A. and Pereira, G. A. and Bortoluzzi, A. J. and Massabni, A. C. and Corbi, P. P.},
 doi = {10.1134/S0022476613010423},
 journal = {Journal of Structural Chemistry},
 number = {1}
}

@article{
 title = {Silver(I) and gold(I) complexes with penicillamine: Synthesis, spectroscopic characterization and biological studies},
 type = {article},
 year = {2012},
 keywords = {Antibacterial assays,DFT,NMR,Penicillamine,gold(I),silver(I)},
 pages = {210-214},
 volume = {34},
 month = {2},
 id = {f4c45914-5087-3e17-93f9-8a6876be3edc},
 created = {2017-03-24T14:12:23.218Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:53:26.943Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {Two new metal complexes of penicillamine (Pen), with molecular formulas [Ag(C 5H 10O 2NS)]·H 2O and [Au(C 5H 10O 2NS)], were synthesized by the reaction of the ligand with, respectively, silver nitrate and potassium dicyanoaurate(I) salts in aqueous solutions. Analytical characterizations of the complexes were based on elemental (C, H, N and S), thermal (TG-DTA) and electrospray ionization mass spectrometry (ESI-MS) analyses. Solid-state 13C nuclear magnetic resonance (SSNMR) and infrared (IR) spectroscopic measurements indicate coordination of Pen to Ag(I) or Au(I) through the sulfur atom. Studies based on density functional theory (DFT) confirmed that Pen acts as an S-donor ligand to Au(I) or Ag(I). Thermal decompositions of the silver(I) and gold(I) complexes start at temperatures near 50 °C, leading to the formation of Ag 0 and Au 0 at 700 °C and 500 °C, respectively. Both complexes are just slightly soluble in common solvents such as water, methanol, ethanol, acetonitrile, hexane and dimethylsulfoxide. An antibiogram assay was performed by the disc diffusion method. The AgPen complex showed antibacterial activities against Escherichia coli and Pseudomonas aeruginosa bacterial strains. © 2012 Elsevier Ltd. All rights reserved.},
 bibtype = {article},
 author = {Costa, Gustavo S M and Corbi, Pedro P. and Abbehausen, Camilla and Formiga, André L B and Lustri, Wilton R. and Cuin, Alexandre},
 doi = {10.1016/j.poly.2012.01.002},
 journal = {Polyhedron},
 number = {1}
}

Two new metal complexes of penicillamine (Pen), with molecular formulas [Ag(C 5H 10O 2NS)]·H 2O and [Au(C 5H 10O 2NS)], were synthesized by the reaction of the ligand with, respectively, silver nitrate and potassium dicyanoaurate(I) salts in aqueous solutions. Analytical characterizations of the complexes were based on elemental (C, H, N and S), thermal (TG-DTA) and electrospray ionization mass spectrometry (ESI-MS) analyses. Solid-state 13C nuclear magnetic resonance (SSNMR) and infrared (IR) spectroscopic measurements indicate coordination of Pen to Ag(I) or Au(I) through the sulfur atom. Studies based on density functional theory (DFT) confirmed that Pen acts as an S-donor ligand to Au(I) or Ag(I). Thermal decompositions of the silver(I) and gold(I) complexes start at temperatures near 50 °C, leading to the formation of Ag 0 and Au 0 at 700 °C and 500 °C, respectively. Both complexes are just slightly soluble in common solvents such as water, methanol, ethanol, acetonitrile, hexane and dimethylsulfoxide. An antibiogram assay was performed by the disc diffusion method. The AgPen complex showed antibacterial activities against Escherichia coli and Pseudomonas aeruginosa bacterial strains. © 2012 Elsevier Ltd. All rights reserved.

@article{
 title = {Studies of the tautomeric equilibrium of 1,3-thiazolidine-2-thione: Theoretical and experimental approaches},
 type = {article},
 year = {2012},
 keywords = {1,1H NMR,3-Thiazolidine-2-thione,3-thiazolidine-2-thione,DFT,Tautomeric equilibrium,tautomeric equilibrium},
 pages = {62-68},
 volume = {408},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S0301010412003606},
 month = {10},
 day = {24},
 id = {7bd4338f-6f4e-36b9-959c-481849bc98d8},
 created = {2017-03-24T14:12:24.394Z},
 accessed = {2016-10-19},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:53:26.952Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 source_type = {JOUR},
 private_publication = {false},
 abstract = {The tautomeric equilibrium of the thione/thiol forms of 1,3-thiazolidine-2-thione was studied by nuclear magnetic resonance, infrared and ultraviolet?visible spectroscopies. Density functional theory was used to support the experimental data and indicates the predominance of the thione tautomer in the solid state, being in agreement with previously reported crystallographic data. In solution, the tautomeric equilibrium was evaluated using 1H NMR at different temperatures in four deuterated solvents acetonitrile, dimethylsulfoxide, chloroform and methanol. The equilibrium constants, K = (thiol)/(thione), and free Gibbs energies were obtained by integration of N bonded hydrogen signals at each temperature for each solvent, excluding methanol. The endothermic tautomerization is entropy-driven and the combined effect of solvent and temperature can be used to achieve almost 50% thiol concentrations in solution. The nature of the electronic transitions was investigated theoretically and the assignment of the bands was made using time-dependent DFT as well as the influence of solvent on the energy of the most important bands of the spectra.},
 bibtype = {article},
 author = {Abbehausen, Camilla and de Paiva, Raphael E.F. F and Formiga, André L.B. B and Corbi, Pedro P.},
 doi = {10.1016/j.chemphys.2012.09.019},
 journal = {Chemical Physics}
}

The tautomeric equilibrium of the thione/thiol forms of 1,3-thiazolidine-2-thione was studied by nuclear magnetic resonance, infrared and ultraviolet?visible spectroscopies. Density functional theory was used to support the experimental data and indicates the predominance of the thione tautomer in the solid state, being in agreement with previously reported crystallographic data. In solution, the tautomeric equilibrium was evaluated using 1H NMR at different temperatures in four deuterated solvents acetonitrile, dimethylsulfoxide, chloroform and methanol. The equilibrium constants, K = (thiol)/(thione), and free Gibbs energies were obtained by integration of N bonded hydrogen signals at each temperature for each solvent, excluding methanol. The endothermic tautomerization is entropy-driven and the combined effect of solvent and temperature can be used to achieve almost 50% thiol concentrations in solution. The nature of the electronic transitions was investigated theoretically and the assignment of the bands was made using time-dependent DFT as well as the influence of solvent on the energy of the most important bands of the spectra.

@article{
 title = {Synthesis, spectroscopic characterization, DFT studies, and initial antibacterial assays in vitro of a new palladium(II) complex with tryptophan},
 type = {article},
 year = {2012},
 keywords = {Antibacterial agent,ESI-QTOF-MS,Infrared,L-Tryptophan,Molecular modeling,palladium(II)},
 pages = {1700-1711},
 volume = {65},
 websites = {http://www.tandfonline.com/doi/abs/10.1080/00958972.2012.679660,http://dx.doi.org/10.1080/00958972.2012.679660},
 month = {5},
 publisher = { Taylor & Francis Group },
 day = {20},
 id = {aadfff10-f06f-3b48-9e9c-765dcaa0e6e6},
 created = {2017-03-24T14:12:25.444Z},
 accessed = {2016-10-19},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:25.444Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {A new palladium(II) complex with the amino acid L-tryptophan (Pd-TRP) was synthesized in aqueous solution and characterized by chemical and spectroscopic methods. Elemental, ESI-QTOF mass spectrometric, and thermal analyses of the solid compound permitted proposing the [Pd(C11H11N2O2)2]?·?2H2O composition. Infrared, Raman, and UV-Vis spectroscopic data indicate the coordination of the ligand to Pd(II) through monodentate oxygen of carboxylate and through nitrogen of the amino group. The 1H and 13C NMR spectroscopic data confirm coordination through the carboxylate, while 15N NMR data confirm coordination of nitrogen of NH2. Density functional theory studies con?rmed nitrogen and oxygen coordination to palladium(II) as a minimum of the potential energy surface with calculations of the hessians showing no imaginary frequencies. Biological studies were performed to provide information concerning the antibacterial activities of the compound. The Pd-TRP complex was shown to be active against Gram-positive and Gram-negative pathogenic bacterial strains.},
 bibtype = {article},
 author = {Carvalho, M.A. A and Souza, B.C. C and Paiva, R.E.F. E F and Bergamini, F.R.G. R G and Gomes, A.F. F and Gozzo, F.C. C and Lustri, W.R. R and Formiga, A.L.B. L B and Rigatto, G. and Corbi, P.P. P},
 doi = {10.1080/00958972.2012.679660},
 journal = {Journal of Coordination Chemistry},
 number = {10}
}

A new palladium(II) complex with the amino acid L-tryptophan (Pd-TRP) was synthesized in aqueous solution and characterized by chemical and spectroscopic methods. Elemental, ESI-QTOF mass spectrometric, and thermal analyses of the solid compound permitted proposing the [Pd(C11H11N2O2)2]?·?2H2O composition. Infrared, Raman, and UV-Vis spectroscopic data indicate the coordination of the ligand to Pd(II) through monodentate oxygen of carboxylate and through nitrogen of the amino group. The 1H and 13C NMR spectroscopic data confirm coordination through the carboxylate, while 15N NMR data confirm coordination of nitrogen of NH2. Density functional theory studies con?rmed nitrogen and oxygen coordination to palladium(II) as a minimum of the potential energy surface with calculations of the hessians showing no imaginary frequencies. Biological studies were performed to provide information concerning the antibacterial activities of the compound. The Pd-TRP complex was shown to be active against Gram-positive and Gram-negative pathogenic bacterial strains.

@article{
 title = {Chemical, spectroscopic characterization, DFT studies and antibacterial activities in vitro of a new gold(I) complex with rimantadine},
 type = {article},
 year = {2012},
 pages = {114-118},
 volume = {89},
 websites = {http://linkinghub.elsevier.com/retrieve/pii/S1386142511011292},
 month = {4},
 id = {ee4b5b98-3e47-33a8-88f7-e09f9d81f8b2},
 created = {2017-03-24T14:12:26.446Z},
 accessed = {2017-03-24},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:26.446Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Sucena, Suelen F. and Paiva, Raphael E.F. and Abbehausen, Camilla and Mattos, Ives B. and Lancellotti, Marcelo and Formiga, André L.B. and Corbi, Pedro P.},
 doi = {10.1016/j.saa.2011.12.043},
 journal = {Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy}
}

@article{
 title = {Synthesis, spectroscopic characterization and molecular modeling of a tetranuclear platinum(II) complex with thiazolidine-4-carboxylic acid},
 type = {article},
 year = {2012},
 pages = {21-26},
 volume = {1019},
 websites = {http://www.sciencedirect.com/science/article/pii/S0022286012003109},
 id = {72045718-f757-3c18-8aad-c16b1d7e1e4c},
 created = {2017-04-06T15:42:53.408Z},
 accessed = {2017-04-06},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:53:27.343Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {The synthesis, spectroscopic characterization and molecular modeling of a novel tetranuclear platinum(II) complex with thiazolidine-4-carboxylic acid (THC) are described. Elemental analysis is consistent with the composition PtCl2C4H7NO2S·H2O. Infrared (IR) spectroscopic results and solid-state 13C and 15N nuclear magnetic resonance (NMR) data indicate coordination of the ligand to Pt(II) through the nitrogen and sulfur atoms. The square planar geometry of the platinum(II) complex is completed by chlorine atoms. Density functional theory (DFT) suggests the formation of a tetrameric cluster as the most probable structure, where each THC molecule bridges between two metal centers. The compound is insoluble in water.},
 bibtype = {article},
 author = {Corbi, Pedro P. and Formiga, André L.B. and Bonk, Fábio A. and Quintão, Frederico A. and Ferraresi, Diego K.D. and Lustri, Wilton R. and Massabni, Antonio C.},
 doi = {10.1016/j.molstruc.2012.03.074},
 journal = {Journal of Molecular Structure}
}

The synthesis, spectroscopic characterization and molecular modeling of a novel tetranuclear platinum(II) complex with thiazolidine-4-carboxylic acid (THC) are described. Elemental analysis is consistent with the composition PtCl2C4H7NO2S·H2O. Infrared (IR) spectroscopic results and solid-state 13C and 15N nuclear magnetic resonance (NMR) data indicate coordination of the ligand to Pt(II) through the nitrogen and sulfur atoms. The square planar geometry of the platinum(II) complex is completed by chlorine atoms. Density functional theory (DFT) suggests the formation of a tetrameric cluster as the most probable structure, where each THC molecule bridges between two metal centers. The compound is insoluble in water.

@article{
 title = {Crystal structure and theoretical studies of the keto-enol isomerism of N,N′-bis(salicylidene)-o-phenylenediamine (salophen)},
 type = {article},
 year = {2012},
 pages = {110-115},
 volume = {99},
 websites = {http://www.sciencedirect.com/science/article/pii/S1386142512008682},
 id = {60d894b5-48ef-3390-863a-125593a575a0},
 created = {2017-04-06T15:43:35.581Z},
 accessed = {2017-04-06},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:53:27.339Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {The Schiff base N,N′-bis(salicylidene)-o-phenylenediamine (salophen) was prepared by the condensation of salicylaldehyde with o-phenylenediamine in ethanol solution. The compound was characterized by elemental analysis, infrared (IR), 1H, 13C and 1H15N HMBC nuclear magnetic resonance (NMR) spectroscopic measurements, and also by X-ray diffraction. The tautomerism of salophen was also studied by calculations using density functional theory (DFT). Two of the three tautomers were shown to coexist. A comparison of the DFT data of the three tautomers has shown that the most stable one is salophen 1, which is in accordance with experimental X-ray crystallographic data.},
 bibtype = {article},
 author = {Mota, Vinicius Z. and de Carvalho, Gustavo S.G. and Corbi, Pedro P. and Bergamini, Fernando R.G. and Formiga, André L.B. and Diniz, Renata and Freitas, Maria C.R. and da Silva, Adilson D. and Cuin, Alexandre},
 doi = {10.1016/j.saa.2012.09.002},
 journal = {Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy}
}

The Schiff base N,N′-bis(salicylidene)-o-phenylenediamine (salophen) was prepared by the condensation of salicylaldehyde with o-phenylenediamine in ethanol solution. The compound was characterized by elemental analysis, infrared (IR), 1H, 13C and 1H15N HMBC nuclear magnetic resonance (NMR) spectroscopic measurements, and also by X-ray diffraction. The tautomerism of salophen was also studied by calculations using density functional theory (DFT). Two of the three tautomers were shown to coexist. A comparison of the DFT data of the three tautomers has shown that the most stable one is salophen 1, which is in accordance with experimental X-ray crystallographic data.

@article{
 title = {Synthesis, spectroscopic characterization, DFT studies and antibacterial assays of a novel silver(I) complex with the anti-inflammatory nimesulide},
 type = {article},
 year = {2012},
 keywords = {2-Mercaptothiazoline,Antibacterial activity,Cytotoxic assays,Infrared spectroscopy,NMR spectroscopy,gold(I)},
 pages = {112-119},
 volume = {36},
 websites = {http://dx.doi.org/10.1016/j.poly.2012.02.002},
 month = {8},
 day = {4},
 id = {cb06e9be-6ad3-37fe-8ced-611063d4dd33},
 created = {2017-04-06T15:44:16.918Z},
 accessed = {2016-10-19},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:53:27.344Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 source_type = {JOUR},
 language = {English},
 private_publication = {false},
 abstract = {A novel silver(I) complex with nimesulide (NMS) of composition AgC 13H 11N 2O 5S was synthesized and characterized by chemical and spectroscopic measurements, density functional theory (DFT) studies and biological assays. Infrared (IR), ESI-QTOF-mass spectrometric (MS) analyses and 1H, 13C and [ 1H- 15N] nuclear magnetic resonance (NMR) studies indicate that NMS acts as a bidentate ligand, being coordinated to Ag(I) through the nitrogen and one of the oxygen atoms of the sulphonamide group. The proposed structure based on the experimental data was confirmed as a minimum of the potential energy surface (PES) with the calculation of the hessians, showing no imaginary frequencies. Also, the theoretical IR spectra of the free ligand and of the silver(I) complex (Ag-NMS) are in a good agreement with the experimental data. Theoretical Time-Dependent DFT (TD-DFT) studies confirmed that the observed transitions in the UV-Vis spectra of the NMS and Ag-NMS are due to π-π * transitions. The antibacterial activity of Ag-NMS was evaluated by an antibiogram assay, using the disk diffusion method. The complex showed an effective antibacterial activity against Staphylococcus aureus (Gram-positive), and Escherichia coli and Pseudomonas aeruginosa (Gram-negative) pathogenic bacterial cells. © 2012 Elsevier Ltd. All rights reserved.},
 bibtype = {article},
 author = {de Paiva, Raphael E.F. F and Abbehausen, Camilla and Gomes, Alexandre F. and Gozzo, Fábio C. and Lustri, Wilton R. and Formiga, André L.B. B and Corbi, Pedro P.},
 doi = {10.1016/j.poly.2012.02.002},
 journal = {Polyhedron},
 number = {1}
}

A novel silver(I) complex with nimesulide (NMS) of composition AgC 13H 11N 2O 5S was synthesized and characterized by chemical and spectroscopic measurements, density functional theory (DFT) studies and biological assays. Infrared (IR), ESI-QTOF-mass spectrometric (MS) analyses and 1H, 13C and [ 1H- 15N] nuclear magnetic resonance (NMR) studies indicate that NMS acts as a bidentate ligand, being coordinated to Ag(I) through the nitrogen and one of the oxygen atoms of the sulphonamide group. The proposed structure based on the experimental data was confirmed as a minimum of the potential energy surface (PES) with the calculation of the hessians, showing no imaginary frequencies. Also, the theoretical IR spectra of the free ligand and of the silver(I) complex (Ag-NMS) are in a good agreement with the experimental data. Theoretical Time-Dependent DFT (TD-DFT) studies confirmed that the observed transitions in the UV-Vis spectra of the NMS and Ag-NMS are due to π-π * transitions. The antibacterial activity of Ag-NMS was evaluated by an antibiogram assay, using the disk diffusion method. The complex showed an effective antibacterial activity against Staphylococcus aureus (Gram-positive), and Escherichia coli and Pseudomonas aeruginosa (Gram-negative) pathogenic bacterial cells. © 2012 Elsevier Ltd. All rights reserved.

@article{
 title = {A binuclear silver complex with l-buthionine sulfoximine: synthesis, spectroscopic characterization, DFT studies and antibacterial assays},
 type = {article},
 year = {2012},
 pages = {10372},
 volume = {2},
 websites = {http://xlink.rsc.org/?DOI=c2ra21433d},
 id = {610ace46-405c-3505-9559-0ee4863cf0b8},
 created = {2018-10-26T20:25:45.747Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T20:25:45.747Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Bergamini, Fernando Rodrigues Goulart and Ferreira, Marcos Antonio and de Paiva, Raphael Enoque Ferraz and Gomes, Alexandre Ferreira and Gozzo, Fábio Cesar and Formiga, André Luiz Barboza and Corbi, Fabiana Cristina Andrade and Mazali, Italo Odone and Alves, Danilo Antonini and Lancellotti, Marcelo and Corbi, Pedro Paulo},
 doi = {10.1039/c2ra21433d},
 journal = {RSC Advances},
 number = {27}
}

@article{
 title = {Synthesis, spectroscopic characterization, DFT studies and biological assays of a novel gold(I) complex with 2-mercaptothiazoline},
 type = {article},
 year = {2011},
 keywords = {2-Mercaptothiazoline,Antibacterial activity,Cytotoxic assays,Gold(I),Infrared spectroscopy,NMR spectroscopy},
 pages = {2354-2359},
 volume = {30},
 month = {8},
 id = {b7fbf494-b912-3f3d-84c1-3ba26d5ae647},
 created = {2017-03-24T14:12:23.518Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:23.518Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {A new gold(I) complex with 2-mercaptothiazoline (MTZ) with the coordination formula [AuCN(C3H5NS2)] was synthesized and characterized by chemical and spectroscopic measurements, DFT studies and biological assays. Infrared (IR) and 1H, 13C and 15N nuclear magnetic resonance (NMR) spectroscopic measurements indicate coordination of the ligand to gold(I) through the nitrogen atom. Studies based on DFT confirmed nitrogen coordination to gold(I) as a minimum of the potential energy surface with calculations of the hessians showing no imaginary frequencies. Thermal decomposition starts at temperatures near 160°C, leading to the formation of Au0 as the final residue at 1000°C. The gold(I) complex with 2-mercaptothiazoline (Au-MTZ) is soluble in dimethyl sulfoxide (DMSO), and is insoluble in water, methanol, ethanol, acetonitrile and hexane. The antibacterial activities of the Au-MTZ complex were evaluated by an antibiogram assay using the disc diffusion method. The compound showed an effective antibacterial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli and Pseudomonas aeruginosa (Gram-negative) bacterial cells. Biological analysis for evaluation of the cytotoxic effect of the Au-MTZ complex was performed using HeLa cells derived from human cervical adenocarcinoma. The complex presented a potent cytotoxic activity, inducing 85% of cell death at a concentration of 2.0 μmol L-1. © 2011 Elsevier Ltd. All rights reserved.},
 bibtype = {article},
 author = {Abbehausen, Camilla and Castro, Juliana F. and Spera, Marcelle B M and Heinrich, Tassiele A. and Costa-Neto, Claudio M. and Lustri, Wilton R. and Formiga, André L B and Corbi, Pedro P.},
 doi = {10.1016/j.poly.2011.06.021},
 journal = {Polyhedron},
 number = {13}
}

A new gold(I) complex with 2-mercaptothiazoline (MTZ) with the coordination formula [AuCN(C3H5NS2)] was synthesized and characterized by chemical and spectroscopic measurements, DFT studies and biological assays. Infrared (IR) and 1H, 13C and 15N nuclear magnetic resonance (NMR) spectroscopic measurements indicate coordination of the ligand to gold(I) through the nitrogen atom. Studies based on DFT confirmed nitrogen coordination to gold(I) as a minimum of the potential energy surface with calculations of the hessians showing no imaginary frequencies. Thermal decomposition starts at temperatures near 160°C, leading to the formation of Au0 as the final residue at 1000°C. The gold(I) complex with 2-mercaptothiazoline (Au-MTZ) is soluble in dimethyl sulfoxide (DMSO), and is insoluble in water, methanol, ethanol, acetonitrile and hexane. The antibacterial activities of the Au-MTZ complex were evaluated by an antibiogram assay using the disc diffusion method. The compound showed an effective antibacterial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli and Pseudomonas aeruginosa (Gram-negative) bacterial cells. Biological analysis for evaluation of the cytotoxic effect of the Au-MTZ complex was performed using HeLa cells derived from human cervical adenocarcinoma. The complex presented a potent cytotoxic activity, inducing 85% of cell death at a concentration of 2.0 μmol L-1. © 2011 Elsevier Ltd. All rights reserved.

@unpublished{
 title = {Chemical, spectroscopic characterization and antibacterial activities in vitro of a novel gold(I)–ibuprofen complex},
 type = {unpublished},
 year = {2011},
 source = {Inorganic Chemistry Communications},
 pages = {738-740},
 volume = {14},
 issue = {5},
 id = {97541e01-6da5-3dfa-83ce-a3b9a03b2495},
 created = {2017-04-06T15:47:26.775Z},
 accessed = {2017-04-06},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:53:27.762Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {A novel gold(I) complex with ibuprofen was synthesized and characterized by chemical and spectroscopic measurements. Elemental analysis led to the composition AuC14H18O2N. Infrared, 1H and 13C NMR data suggest coordination of the ligand to Au(I) through the oxygen atom of the carboxylic group in a monodentate form. An antibiotic sensitive profile indicated antibacterial activity in vitro of the complex against Gram-negative (E. coli and P. aeruginosa) and Gram-positive (S. aureus) microorganisms.},
 bibtype = {unpublished},
 author = {Fiori, Ana Thereza M. and Lustri, Wilton R. and Magalhães, Alviclér and Corbi, Pedro P.},
 doi = {10.1016/j.inoche.2011.02.024}
}

A novel gold(I) complex with ibuprofen was synthesized and characterized by chemical and spectroscopic measurements. Elemental analysis led to the composition AuC14H18O2N. Infrared, 1H and 13C NMR data suggest coordination of the ligand to Au(I) through the oxygen atom of the carboxylic group in a monodentate form. An antibiotic sensitive profile indicated antibacterial activity in vitro of the complex against Gram-negative (E. coli and P. aeruginosa) and Gram-positive (S. aureus) microorganisms.

@article{
 title = {Synthesis, spectroscopic characterization, and antibacterial assays <i>in vitro</i> of a new platinum(II) complex with methionine sulfoxide},
 type = {article},
 year = {2011},
 keywords = {Antibacterial activity,Mass spectrometry,Methionine sulfoxide,NMR spectroscopy,Platinum(II)},
 pages = {272-280},
 volume = {64},
 websites = {http://www.tandfonline.com/doi/abs/10.1080/00958972.2010.540325},
 month = {1},
 publisher = { Taylor & Francis Group },
 day = {20},
 id = {ea7744c5-0494-3314-8c12-a4215d2a28f9},
 created = {2017-04-06T15:47:33.591Z},
 accessed = {2017-04-06},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-04-06T15:47:33.591Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {A new platinum(II) complex with methionine sulfoxide was synthesized and characterized by chemical and spectroscopic techniques. Elemental analyses, mass spectrometric measurements (electrospray ionization quadrupole time-of-flight mass spectrometry), and thermal analyses of the solid compound fit the composition [(C5H10NO3S)Pt(µ-Cl)2Pt(C5H10NO3S)] · 2.5H2O. Infrared spectroscopic data indicate coordination of the ligand to Pt(II) through the nitrogen of NH2 and the sulfur of the S=O group. 1H-15N nuclear magnetic resonance spectroscopic data confirm nitrogen coordination. Antibacterial activities were evaluated by antibiogram assays using the disc diffusion method. The platinum(II) complex showed antibacterial activity against Gram-negative Pseudomonas aeruginosa bacterial cells.},
 bibtype = {article},
 author = {Castello, W.S. and Spera, M.B.M. and Gomes, A.F. and Gozzo, F.C. and Lustri, W.R. and Formiga, A.L.B. and Corbi, P.P.},
 doi = {10.1080/00958972.2010.540325},
 journal = {Journal of Coordination Chemistry},
 number = {2}
}

A new platinum(II) complex with methionine sulfoxide was synthesized and characterized by chemical and spectroscopic techniques. Elemental analyses, mass spectrometric measurements (electrospray ionization quadrupole time-of-flight mass spectrometry), and thermal analyses of the solid compound fit the composition [(C5H10NO3S)Pt(µ-Cl)2Pt(C5H10NO3S)] · 2.5H2O. Infrared spectroscopic data indicate coordination of the ligand to Pt(II) through the nitrogen of NH2 and the sulfur of the S=O group. 1H-15N nuclear magnetic resonance spectroscopic data confirm nitrogen coordination. Antibacterial activities were evaluated by antibiogram assays using the disc diffusion method. The platinum(II) complex showed antibacterial activity against Gram-negative Pseudomonas aeruginosa bacterial cells.

@article{
 title = {Palladium(II) complex with S-allyl-l-cysteine: New solid-state NMR spectroscopic measurements, molecular modeling and antibacterial assays},
 type = {article},
 year = {2011},
 pages = {313-318},
 volume = {78},
 websites = {http://www.sciencedirect.com/science/article/pii/S1386142510005287},
 id = {cafe4b0d-deb9-39f9-90ef-ed7837b072eb},
 created = {2017-04-06T15:47:39.411Z},
 accessed = {2017-04-06},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:53:27.759Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {Nuclear magnetic resonance studies, molecular modeling and antibacterial assays of the palladium(II) complex with S-allyl-l-cysteine (deoxyalliin) are presented. Studies based on solid and solution 13C and 15N nuclear magnetic resonance (NMR) spectroscopy confirmed that the palladium(II) complex preserved the same structural arrangement in both states, with no modifications on coordination sphere when dissolved in water. Density functional theory (DFT) studies stated that the trans isomer is the most stable one. Antibacterial activities of S-allyl-l-cysteine and its palladium(II) complex were evaluated by antibiogram assays using the disc diffusion method. The palladium(II) complex showed an effective antibacterial activity against Staphylococcus aureus (Gram-positive), Escherichia coli and Pseudomonas aeruginosa (Gram-negative) bacterial cells.},
 bibtype = {article},
 author = {Spera, Marcelle B.M. and Quintão, Frederico A. and Ferraresi, Diego K.D. and Lustri, Wilton R. and Magalhães, Alviclér and Formiga, André L.B. and Corbi, Pedro P.},
 doi = {10.1016/j.saa.2010.10.012},
 journal = {Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy},
 number = {1}
}

Nuclear magnetic resonance studies, molecular modeling and antibacterial assays of the palladium(II) complex with S-allyl-l-cysteine (deoxyalliin) are presented. Studies based on solid and solution 13C and 15N nuclear magnetic resonance (NMR) spectroscopy confirmed that the palladium(II) complex preserved the same structural arrangement in both states, with no modifications on coordination sphere when dissolved in water. Density functional theory (DFT) studies stated that the trans isomer is the most stable one. Antibacterial activities of S-allyl-l-cysteine and its palladium(II) complex were evaluated by antibiogram assays using the disc diffusion method. The palladium(II) complex showed an effective antibacterial activity against Staphylococcus aureus (Gram-positive), Escherichia coli and Pseudomonas aeruginosa (Gram-negative) bacterial cells.

@article{
 title = {Chemical, spectroscopic characterization, DFT studies and initial pharmacological assays of a silver(I) complex with N-acetyl-l-cysteine},
 type = {article},
 year = {2011},
 pages = {579-583},
 volume = {30},
 websites = {http://www.sciencedirect.com/science/article/pii/S027753871000567X},
 id = {e6ef4fec-d4af-353c-9142-a081016ea22f},
 created = {2017-04-06T15:47:53.954Z},
 accessed = {2017-04-06},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-12-29T00:53:27.771Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {A new silver(I) complex with N-acetyl-l-cysteine (NAC) of composition AgC5H8NO3S·H2O was synthesized and characterized by a set of chemical and spectroscopic measurements. Solid-state 13C nuclear magnetic resonance (SSNMR) and infrared (IR) analyses indicate the coordination of the ligand to Ag(I) through the sulfur atom. The Ag–NAC complex is slightly soluble in dimethyl sulfoxide. It is insoluble in water, methanol, ethanol, acetone and hexane. Antibacterial activity of the silver complex with N-acetyl-l-cysteine (Ag–NAC) was evaluated by antibiogram assays using the disc diffusion method. The compound showed an effective antibacterial activity against Staphylococcus aureus (Gram-positive), Escherichia coli and Pseudomonas aeruginosa (Gram-negative) bacterial cells. Biological analysis for evaluation of a potential cytotoxic effect of Ag–NAC was performed using HeLa cells derived from human cervical adenocarcinoma. The complex presented a significant cytotoxic activity, inducing 80% of cell death at a concentration of 200μmolL−1.},
 bibtype = {article},
 author = {Abbehausen, Camilla and Heinrich, Tassiele A. and Abrão, Emiliana P. and Costa-Neto, Claudio M. and Lustri, Wilton R. and Formiga, André L.B. and Corbi, Pedro P.},
 doi = {10.1016/j.poly.2010.11.025},
 journal = {Polyhedron},
 number = {4}
}

A new silver(I) complex with N-acetyl-l-cysteine (NAC) of composition AgC5H8NO3S·H2O was synthesized and characterized by a set of chemical and spectroscopic measurements. Solid-state 13C nuclear magnetic resonance (SSNMR) and infrared (IR) analyses indicate the coordination of the ligand to Ag(I) through the sulfur atom. The Ag–NAC complex is slightly soluble in dimethyl sulfoxide. It is insoluble in water, methanol, ethanol, acetone and hexane. Antibacterial activity of the silver complex with N-acetyl-l-cysteine (Ag–NAC) was evaluated by antibiogram assays using the disc diffusion method. The compound showed an effective antibacterial activity against Staphylococcus aureus (Gram-positive), Escherichia coli and Pseudomonas aeruginosa (Gram-negative) bacterial cells. Biological analysis for evaluation of a potential cytotoxic effect of Ag–NAC was performed using HeLa cells derived from human cervical adenocarcinoma. The complex presented a significant cytotoxic activity, inducing 80% of cell death at a concentration of 200μmolL−1.

@article{
 title = {Synthesis, spectroscopic studies, and preliminary antibacterial assays of a palladium(II) complex with 2-mercaptothiazoline},
 type = {article},
 year = {2011},
 pages = {3092-3101},
 volume = {64},
 websites = {http://www.tandfonline.com/doi/abs/10.1080/00958972.2011.613463},
 month = {9},
 day = {10},
 id = {d632c536-4572-3518-90ef-2b3b11327bf7},
 created = {2018-10-26T19:26:49.239Z},
 file_attached = {false},
 profile_id = {dd5b9595-8664-345f-9f12-472af749995c},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T19:26:49.239Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Bergamini, F.R.G. and Abbehausen, C. and Magalhães, A. and Lustri, W.R. and Gomes, A.F. and Gozzo, F.C. and Corbi, P.P.},
 doi = {10.1080/00958972.2011.613463},
 journal = {Journal of Coordination Chemistry},
 number = {17}
}

@article{
 title = {Pt(II) and Ag(I) complexes with acesulfame: crystal structure and a study of their antitumoral, antimicrobial and antiviral activities.},
 type = {article},
 year = {2010},
 keywords = {Acesulfame-K,Antibiotic,antitumor agents,platinum,silver},
 pages = {533-40},
 volume = {104},
 websites = {http://www.sciencedirect.com/science/article/pii/S0162013410000085},
 month = {5},
 id = {94cd7e1d-822e-3112-9dad-0a2cfdbff6d4},
 created = {2017-03-24T14:12:24.886Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:24.886Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {Two new complexes of platinum(II) and silver(I) with acesulfame were synthesized. Acesulfame is in the anionic form acesulfamate (ace). The structures of both complexes were determined by X-ray crystallography. For K(2)[PtCl(2)(ace)(2)] the platinum atom is coordinated to two Cl(-) and two N-acesulfamate atoms forming a trans-square planar geometry. Each K(+) ion interacts with two oxygen atoms of the S(O)(2) group of each acesulfamate. For the polymeric complex [Ag(ace)](n) the water molecule bridges between two crystallographic equivalent Ag1 atoms which are related each other by a twofold symmetry axis. Two Ag1 atoms, related to each other by a symmetry centre, make bond contact with two equivalent oxygen atoms. These bonds give rise to infinite chains along the unit cell diagonal in the ac plane. The in vitro cytotoxic analyses for the platinum complex using HeLa (human cervix cancer) cells show its low activity when compared to the vehicle-treated cells. The Ag(I) complex submitted to in vitro antimycobacterial tests, using the Microplate Alamar Blue (MABA) method, showed a good activity against Mycobacterium tuberculosis, responsible for tuberculosis, with a minimal inhibitory concentration (MIC) value of 11.6microM. The Ag(I) complex also presented a promising activity against Gram negative (Escherichia coli and Pseudomonas aeruginosa) and Gram positive (Enterococcus faecalis) microorganisms. The complex K(2)[PtCl(2)(ace)(2)] was also evaluated for antiviral properties against dengue virus type 2 (New Guinea C strain) in Vero cells and showed a good inhibition of dengue virus type 2 (New Guinea C strain) replication at 200microM, when compared to vehicle-treated cells.},
 bibtype = {article},
 author = {Cavicchioli, Maurício and Massabni, Antonio C and Heinrich, Tassiele A and Costa-Neto, Claudio M and Abrão, Emiliana P and Fonseca, Benedito A L and Castellano, Eduardo E and Corbi, Pedro P and Lustri, Wilton R and Leite, Clarice Q F},
 doi = {10.1016/j.jinorgbio.2010.01.004},
 journal = {Journal of inorganic biochemistry},
 number = {5}
}

Two new complexes of platinum(II) and silver(I) with acesulfame were synthesized. Acesulfame is in the anionic form acesulfamate (ace). The structures of both complexes were determined by X-ray crystallography. For K(2)[PtCl(2)(ace)(2)] the platinum atom is coordinated to two Cl(-) and two N-acesulfamate atoms forming a trans-square planar geometry. Each K(+) ion interacts with two oxygen atoms of the S(O)(2) group of each acesulfamate. For the polymeric complex [Ag(ace)](n) the water molecule bridges between two crystallographic equivalent Ag1 atoms which are related each other by a twofold symmetry axis. Two Ag1 atoms, related to each other by a symmetry centre, make bond contact with two equivalent oxygen atoms. These bonds give rise to infinite chains along the unit cell diagonal in the ac plane. The in vitro cytotoxic analyses for the platinum complex using HeLa (human cervix cancer) cells show its low activity when compared to the vehicle-treated cells. The Ag(I) complex submitted to in vitro antimycobacterial tests, using the Microplate Alamar Blue (MABA) method, showed a good activity against Mycobacterium tuberculosis, responsible for tuberculosis, with a minimal inhibitory concentration (MIC) value of 11.6microM. The Ag(I) complex also presented a promising activity against Gram negative (Escherichia coli and Pseudomonas aeruginosa) and Gram positive (Enterococcus faecalis) microorganisms. The complex K(2)[PtCl(2)(ace)(2)] was also evaluated for antiviral properties against dengue virus type 2 (New Guinea C strain) in Vero cells and showed a good inhibition of dengue virus type 2 (New Guinea C strain) replication at 200microM, when compared to vehicle-treated cells.

@article{
 title = {Chemical, spectroscopic characterization, and in vitro antibacterial studies of a new gold(I) complex with N -acetyl- L -cysteine},
 type = {article},
 year = {2010},
 keywords = {Antibacterial activity,Gold(I),Infrared spectroscopy,N-acetyl-L-cysteine,NMR spectroscopy},
 pages = {1390-1397},
 volume = {63},
 websites = {http://www.tandfonline.com/doi/abs/10.1080/00958971003782608},
 month = {4},
 publisher = {Taylor & Francis Group},
 day = {20},
 id = {70ed5ce0-1b13-388b-8e2a-a1d2fcc06d16},
 created = {2017-04-06T15:49:38.511Z},
 accessed = {2017-04-06},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T19:27:11.896Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {A new gold(I) complex with N-acetyl-L-cysteine was synthesized and characterized by chemical and spectroscopic techniques. The elemental and thermal analyses of the solid compound fit to the composition AuC5H8NO3S · 0.75H2O. Solid-state 13C-nuclear magnetic resonance (SSNMR) and infrared (IR) analyses indicate the coordination of the ligand to Au(I) through sulfur. The insolubility of the complex in both polar and non-polar solvents supports a polymeric structure. The antibacterial activity of the complex was evaluated by antibiogram assays using the disc diffusion method. The compound showed effective antibacterial activity against Staphylococcus aureus (Gram positive) and Escherichia coli (Gram negative) bacterial cells.},
 bibtype = {article},
 author = {Corbi, P.P. and Quintão, F.A. and Ferraresi, D.K.D. and Lustri, W.R. and Amaral, A.C. and Massabni, A.C.},
 doi = {10.1080/00958971003782608},
 journal = {Journal of Coordination Chemistry},
 number = {8}
}

A new gold(I) complex with N-acetyl-L-cysteine was synthesized and characterized by chemical and spectroscopic techniques. The elemental and thermal analyses of the solid compound fit to the composition AuC5H8NO3S · 0.75H2O. Solid-state 13C-nuclear magnetic resonance (SSNMR) and infrared (IR) analyses indicate the coordination of the ligand to Au(I) through sulfur. The insolubility of the complex in both polar and non-polar solvents supports a polymeric structure. The antibacterial activity of the complex was evaluated by antibiogram assays using the disc diffusion method. The compound showed effective antibacterial activity against Staphylococcus aureus (Gram positive) and Escherichia coli (Gram negative) bacterial cells.

@article{
 title = {Synthesis and characterization of a platinum(II) complex with N-acetyl-L-cysteine},
 type = {article},
 year = {2009},
 pages = {2764-2771},
 volume = {62},
 id = {b76c4ec6-d822-3fb9-8576-fc24edd0e6c9},
 created = {2017-03-24T14:12:26.988Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:26.988Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {Synthesis and spectroscopic studies in the solid-state of a platinum(II) complex with N-acetyl-L-cysteine are described. Elemental analyses are consistent with composition Pt2(C5H8NO3S)4 center dot 3H2O. Solid-state 13C NMR, infrared, and U-Vis spectroscopic results are consistent with coordination of the ligand to platinum(II) through sulfur. Thermal analyses confirmed water in the complex composition. Final residue of the thermal treatment was identified by powder X-ray diffractometry as metallic platinum.},
 bibtype = {article},
 author = {Corbi, P. P. and Cagnin, F. and Massabni, A. C.},
 doi = {10.1080/00958970902942974},
 journal = {Journal of Coordination Chemistry},
 number = {17},
 keywords = {Infrared spectroscopy,N-Acetyl-L-cysteine,Platinum(II),Solid-state NMR,Thermal analysis}
}

Synthesis and spectroscopic studies in the solid-state of a platinum(II) complex with N-acetyl-L-cysteine are described. Elemental analyses are consistent with composition Pt2(C5H8NO3S)4 center dot 3H2O. Solid-state 13C NMR, infrared, and U-Vis spectroscopic results are consistent with coordination of the ligand to platinum(II) through sulfur. Thermal analyses confirmed water in the complex composition. Final residue of the thermal treatment was identified by powder X-ray diffractometry as metallic platinum.

@article{
 title = {Chemical and spectroscopic studies of a new palladium(II) complex with N-acetyl-L-cysteine},
 type = {article},
 year = {2008},
 pages = {3666-3673},
 volume = {61},
 id = {6b29e4ea-4f6d-3a25-8dc1-236c4de3e1c8},
 created = {2017-03-24T14:12:23.123Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:23.123Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {Chemical and spectroscopic studies of a new palladium(II) N-acetyl-L-cysteine complex are described. Elemental analyses for the solid complex are consistent with the formula [Pd(C(5)H(8)NO(3)S)(2)] H(2)O or [Pd(NAC)(2)] H(2)O. Solid-state (13)C nuclear magnetic resonance (NMR), UV-Visible (UV-Vis) and infrared (IR) spectroscopic analyses are consistent with coordination of the ligand to palladium(II) through the nitrogen and sulfur atoms in a square-planar geometry. Thermogravimetric and differential thermal analyses confirmed the composition; final residue was identified as metallic palladium.},
 bibtype = {article},
 author = {Corbi, P. P. and Cagnin, F. and Massabni, A. C.},
 doi = {10.1080/00958970802108809},
 journal = {Journal of Coordination Chemistry},
 number = {22},
 keywords = {(13)C NMR,Infrared spectroscopy,N-Acetyl-L-cysteine,Thermal analysis,UV-Vis,palladium(II)}
}

Chemical and spectroscopic studies of a new palladium(II) N-acetyl-L-cysteine complex are described. Elemental analyses for the solid complex are consistent with the formula [Pd(C(5)H(8)NO(3)S)(2)] H(2)O or [Pd(NAC)(2)] H(2)O. Solid-state (13)C nuclear magnetic resonance (NMR), UV-Visible (UV-Vis) and infrared (IR) spectroscopic analyses are consistent with coordination of the ligand to palladium(II) through the nitrogen and sulfur atoms in a square-planar geometry. Thermogravimetric and differential thermal analyses confirmed the composition; final residue was identified as metallic palladium.

@article{
 title = {Lithium thiazolidine-4-carboxylate: Synthesis, spectroscopic characterization and preliminary in vitro cytotoxic studies in human HeLa cells},
 type = {article},
 year = {2008},
 keywords = {Cytotoxicity,Infrared spectroscopy,NMR spectroscopy,thiazolidine-4-carboxylic acid},
 pages = {929-931},
 volume = {71},
 month = {12},
 id = {816ee81b-9dd9-3a5f-9c3b-12a4c17ae730},
 created = {2017-03-24T14:12:24.630Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:24.630Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {A new water-soluble lithium salt of thiazolidine-4-carboxylic acid was synthesized and characterized by chemical and spectroscopic techniques. Elemental and mass spectrometric (ESI-MS) analyses of the solid compound fit to the composition LiC4H6NSO2. 1H, 13C nuclear magnetic resonance (NMR), [1H-15N] NMR and infrared (IR) analyses permitted to elucidate the structure of the compound. Biological activity was evaluated by cytotoxic analysis using HeLa cells. Determination of cell death was assessed using a tetrazolium salt colorimetric assay, which reflects the cells viability. © 2008 Elsevier B.V. All rights reserved.},
 bibtype = {article},
 author = {Corbi, Pedro P. and Andrade, Fabiana C. and Massabni, Antonio C. and Heinrich, Tassiele a. and Souza, P. P C and Costa-Neto, Cláudio M.},
 doi = {10.1016/j.saa.2008.02.013},
 journal = {Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy},
 number = {3}
}

A new water-soluble lithium salt of thiazolidine-4-carboxylic acid was synthesized and characterized by chemical and spectroscopic techniques. Elemental and mass spectrometric (ESI-MS) analyses of the solid compound fit to the composition LiC4H6NSO2. 1H, 13C nuclear magnetic resonance (NMR), [1H-15N] NMR and infrared (IR) analyses permitted to elucidate the structure of the compound. Biological activity was evaluated by cytotoxic analysis using HeLa cells. Determination of cell death was assessed using a tetrazolium salt colorimetric assay, which reflects the cells viability. © 2008 Elsevier B.V. All rights reserved.

@article{
 title = {Characterization and biological studies of a new platinum(II) complex with the amino acid L-alliin},
 type = {article},
 year = {2008},
 keywords = {15N resonance,L-alliin,S-allyl-L-cysteine sulfoxide,cytotoxicity,platinum(II)},
 pages = {2470-2477},
 volume = {61},
 websites = {http://www.tandfonline.com/doi/abs/10.1080/00958970801930005},
 month = {8},
 publisher = { Taylor & Francis Group },
 day = {10},
 id = {179215f4-741f-33bd-92c9-b4eb98fbbe3e},
 created = {2017-04-06T15:51:03.277Z},
 accessed = {2017-04-06},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-04-06T15:51:03.277Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {Synthesis and characterization of a new Pt(II) complex with the amino acid L-alliin (S-allyl-L-cysteine sulfoxide, C6H11NO3S) are described. Elemental and mass spectrometric analyses of the solid complex are consistent with [PtCl2(alliin)], or [PtCl2(C6H11NO3S)]. 13C nuclear magnetic resonance (NMR), [1H–15N] two dimensional (2D) NMR and infrared spectroscopy indicate coordination of the ligand to Pt(II) through the N and S atoms. The complex is very soluble in dimethyl sulfoxide. Biological analysis for evaluation of a potential cytotoxic effect of the complex was performed using HeLa cells derived from human cervical adenocarcinoma. The complex presented moderate cytotoxic activity, inducing about 40% cell death at a concentration of 400 μmol  · L−1.},
 bibtype = {article},
 author = {Corbi, P. P. and Massabni, A. C. and Sabeh, L. P. B. and Costa-Neto, C. M.},
 doi = {10.1080/00958970801930005},
 journal = {Journal of Coordination Chemistry},
 number = {15}
}

Synthesis and characterization of a new Pt(II) complex with the amino acid L-alliin (S-allyl-L-cysteine sulfoxide, C6H11NO3S) are described. Elemental and mass spectrometric analyses of the solid complex are consistent with [PtCl2(alliin)], or [PtCl2(C6H11NO3S)]. 13C nuclear magnetic resonance (NMR), [1H–15N] two dimensional (2D) NMR and infrared spectroscopy indicate coordination of the ligand to Pt(II) through the N and S atoms. The complex is very soluble in dimethyl sulfoxide. Biological analysis for evaluation of a potential cytotoxic effect of the complex was performed using HeLa cells derived from human cervical adenocarcinoma. The complex presented moderate cytotoxic activity, inducing about 40% cell death at a concentration of 400 μmol  · L−1.

@article{
 title = {Crystal structure and infrared analysis of a new trinuclear platinum(II) complex with L-cysteine},
 type = {article},
 year = {2007},
 keywords = {X-ray,crystallography,cysteine,infrared analysis,platinum},
 pages = {91-95},
 volume = {37},
 month = {2},
 id = {243c1c33-a7f0-37d8-be46-67f7e9df0c62},
 created = {2017-03-24T14:12:23.225Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:23.225Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {A new trinuclear platinum(II) complex with cysteine of composition [Pt(C3H6NO2S)Cl](3)center dot(C2H6SO)(3) was obtained and structurally characterized by X-ray diffraction and infrared analysis. The compound crystallizes in the trigonal system, space group R3, and is described in a hexagonal cell with a=17.739(1), c=9.531(1) and Z=3. Cysteine is coordinated to Pt(II) through the nitrogen and sulphur atoms. Each cysteine sulphur bridges between two metal atoms. A square planar coordination sphere of platinum is completed by a chlorine atom. The complex is soluble in dimethyl sulfoxide.},
 bibtype = {article},
 author = {Corbi, Pedro P. and Castellano, Eduardo E. and Cagnin, Flávia and Massabni, Antonio C.},
 doi = {10.1007/s10870-006-9151-z},
 journal = {Journal of Chemical Crystallography},
 number = {2}
}

A new trinuclear platinum(II) complex with cysteine of composition [Pt(C3H6NO2S)Cl](3)center dot(C2H6SO)(3) was obtained and structurally characterized by X-ray diffraction and infrared analysis. The compound crystallizes in the trigonal system, space group R3, and is described in a hexagonal cell with a=17.739(1), c=9.531(1) and Z=3. Cysteine is coordinated to Pt(II) through the nitrogen and sulphur atoms. Each cysteine sulphur bridges between two metal atoms. A square planar coordination sphere of platinum is completed by a chlorine atom. The complex is soluble in dimethyl sulfoxide.

@article{
 title = {Synthesis, spectroscopic characterization and biological analysis of a new palladium(II) complex with methionine sulfoxide.},
 type = {article},
 year = {2007},
 keywords = {Cytotoxicity,Infrared spectroscopy,Methionine sulfoxide,N-15 NMR,antitumor,palladium(II)},
 pages = {1171-4},
 volume = {66},
 websites = {http://www.sciencedirect.com/science/article/pii/S1386142506003337},
 month = {4},
 id = {c4ca41aa-83be-32d2-8b29-01d544fa3562},
 created = {2017-03-24T14:12:24.067Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:24.067Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {A new palladium(II) complex with methionine sulfoxide was synthesized and characterized by a set of chemical and spectroscopic techniques. Elemental and mass spectrometry analyses of the solid complex fit to the composition [Pd(C5H10NO3S)2].H2O. 13C NMR, [1H-15N] NMR and infrared spectra indicate coordination of the amino acid to Pd(II) through the carboxylate and amino groups in a square planar geometry. The complex is soluble in water. Biological activity was evaluated by cytotoxic analysis using HeLa cells. Determination of cell death was assessed using a tetrazolium salt colorimetric assay, which reflects the cells viability. After incubation for 48 h, 20% of cell death was achieved at a concentration of 200 micromol L-1 of the complex.},
 bibtype = {article},
 author = {Corbi, Pedro P and Cagnin, Flávia and Sabeh, Lilian P B and Massabni, Antonio C and Costa-Neto, Claudio M},
 doi = {10.1016/j.saa.2006.06.003},
 journal = {Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy},
 number = {4-5}
}

A new palladium(II) complex with methionine sulfoxide was synthesized and characterized by a set of chemical and spectroscopic techniques. Elemental and mass spectrometry analyses of the solid complex fit to the composition [Pd(C5H10NO3S)2].H2O. 13C NMR, [1H-15N] NMR and infrared spectra indicate coordination of the amino acid to Pd(II) through the carboxylate and amino groups in a square planar geometry. The complex is soluble in water. Biological activity was evaluated by cytotoxic analysis using HeLa cells. Determination of cell death was assessed using a tetrazolium salt colorimetric assay, which reflects the cells viability. After incubation for 48 h, 20% of cell death was achieved at a concentration of 200 micromol L-1 of the complex.

@article{
 title = {1H-15N NMR studies of the complex bis(S-allyl-L-cysteinate)palladium(II).},
 type = {article},
 year = {2006},
 keywords = {N-15 NMR,S-allyl-L-cysteine,deoxyallim,palladium(II)},
 pages = {418-9},
 volume = {64},
 websites = {http://www.ncbi.nlm.nih.gov/pubmed/16458061},
 month = {5},
 id = {9506501f-8625-3ea9-9a78-fffd018ae13c},
 created = {2017-03-24T14:12:25.003Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:25.003Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {1H-15N 2D NMR data for S-allyl-L-cysteine (deoxyalliin) and for bis(S-allyl-L-cysteinate)palladium(II) complex are presented in this manuscript. Large upfield 15N NMR shift of the amine nitrogen in the spectrum of the complex when compared to the spectrum of the ligand shows clearly coordination of S-allyl-L-cysteine, in the anion form, to palladium(II) through the NH2 group.},
 bibtype = {article},
 author = {Corbi, Pedro P and Massabni, Antonio C},
 doi = {10.1016/j.saa.2005.07.039},
 journal = {Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy},
 number = {2}
}

1H-15N 2D NMR data for S-allyl-L-cysteine (deoxyalliin) and for bis(S-allyl-L-cysteinate)palladium(II) complex are presented in this manuscript. Large upfield 15N NMR shift of the amine nitrogen in the spectrum of the complex when compared to the spectrum of the ligand shows clearly coordination of S-allyl-L-cysteine, in the anion form, to palladium(II) through the NH2 group.

@article{
 title = {Four new metal complexes with the amino acid deoxyalliin},
 type = {article},
 year = {2005},
 pages = {718-722},
 volume = {16},
 month = {8},
 id = {30eec088-7c26-33da-8905-37a4290dc0b9},
 created = {2017-03-24T14:12:23.940Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:23.940Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {The solid complexes [Co(C(6)H(10)NO(2)S)(2)], [Ni(C(6)H(10)NO(2)S)(2)], [Cu(C(6)H(10)NO(2)S)(2)] and [Fe(C(6)H(10)NO(2)S)(2)] were obtained from the reaction of cobalt(II), nickel(II), copper(II) and iron(II) salts with the potassium salt of the amino acid deoxyalliin (S-allyl-L-cysteine). Electronic absorption spectra of the complexes are typical of octahedral structures. Infrared spectroscopy confirms the ligand coordination to the metal ions through (COO-) and (NH(2)) groups. EPR spectrum of the Cu(II) complex indicates a slight distortion of its octahedral symmetry. Mossbauer parameters permitted to identify the presence of iron(II) and iron(III) species in the same sample, both of octahedral geometry. Thermal decomposition of the complexes lead to the formation of CoO, NiO, CuO and Fe(2)O(3) as final products. The compounds show poor solubility in water and in the common organic solvents.},
 bibtype = {article},
 author = {Massabni, AC and Corbi, PP and Melnikov, P and Zacharias, MA and Rechenberg, HR},
 journal = {Journal of the Brazilian Chemical Society},
 number = {4},
 keywords = {cobalt,copper,deoxyalliin,iron,nickel}
}

The solid complexes [Co(C(6)H(10)NO(2)S)(2)], [Ni(C(6)H(10)NO(2)S)(2)], [Cu(C(6)H(10)NO(2)S)(2)] and [Fe(C(6)H(10)NO(2)S)(2)] were obtained from the reaction of cobalt(II), nickel(II), copper(II) and iron(II) salts with the potassium salt of the amino acid deoxyalliin (S-allyl-L-cysteine). Electronic absorption spectra of the complexes are typical of octahedral structures. Infrared spectroscopy confirms the ligand coordination to the metal ions through (COO-) and (NH(2)) groups. EPR spectrum of the Cu(II) complex indicates a slight distortion of its octahedral symmetry. Mossbauer parameters permitted to identify the presence of iron(II) and iron(III) species in the same sample, both of octahedral geometry. Thermal decomposition of the complexes lead to the formation of CoO, NiO, CuO and Fe(2)O(3) as final products. The compounds show poor solubility in water and in the common organic solvents.

@article{
 title = {Synthesis, characterization, and biological activity of a new palladium(II) complex with deoxyalliin},
 type = {article},
 year = {2005},
 keywords = {S-allyl-L-cysteine,cancer,deoxyalliin,palladium( II),tumor cells},
 pages = {104-109},
 volume = {83},
 month = {2},
 id = {dcb42de2-6a75-3fb5-9c8a-1996833fd969},
 created = {2017-03-24T14:12:25.749Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:25.749Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {Synthesis, characterization, and biological activity of a new water-soluble Pd(II)-deoxyalliin (S-allyl-L-cysteine) complex are described in this article. Elemental and thermal analysis for the complex are consistent with the formula [Pd(C6H10NO2S)(2)]. C-13 NMR, H-1 NMR, and IR spectroscopy show coordination of the ligand to Pd(II) through S and N atoms in a square planar geometry. Final residue of the thermal treatment was identified as a mixture of PdO and metallic Pd. Antiproliferative assays using aqueous solutions of the complex against HeLa and TM5 tumor cells showed a pronounced activity of the complex even at low concentrations. After incubation for 24 h, the complex induced cytotoxic effect over HeLa cells when used at concentrations higher than 0.40 mmol/L. At lower concentrations, the complex was nontoxic, indicating its action is probably due to cell cycle arrest, rather than cell death. In agreement with these results, the flow cytometric analysis indicated that after incubation for 24 h at low concentrations of the complex cells are arrested in G0/G1.},
 bibtype = {article},
 author = {Corbi, Pedro P and Massabni, Antonio C and Moreira, Andréia G and Medrano, Francisco J and Jasiulionis, Miriam G and Costa-Neto, Claudio M},
 doi = {10.1139/v05-003},
 journal = {Canadian Journal of Chemistry},
 number = {2}
}

Synthesis, characterization, and biological activity of a new water-soluble Pd(II)-deoxyalliin (S-allyl-L-cysteine) complex are described in this article. Elemental and thermal analysis for the complex are consistent with the formula [Pd(C6H10NO2S)(2)]. C-13 NMR, H-1 NMR, and IR spectroscopy show coordination of the ligand to Pd(II) through S and N atoms in a square planar geometry. Final residue of the thermal treatment was identified as a mixture of PdO and metallic Pd. Antiproliferative assays using aqueous solutions of the complex against HeLa and TM5 tumor cells showed a pronounced activity of the complex even at low concentrations. After incubation for 24 h, the complex induced cytotoxic effect over HeLa cells when used at concentrations higher than 0.40 mmol/L. At lower concentrations, the complex was nontoxic, indicating its action is probably due to cell cycle arrest, rather than cell death. In agreement with these results, the flow cytometric analysis indicated that after incubation for 24 h at low concentrations of the complex cells are arrested in G0/G1.

@article{
 title = {Synthesis and characterization of a new platinum(II) complex with L -mimosine},
 type = {article},
 year = {2005},
 pages = {1477-1483},
 volume = {58},
 websites = {http://www.tandfonline.com/doi/abs/10.1080/00958970500236209},
 month = {11},
 id = {5688afe6-6826-3136-acbc-2beb3c8f8fbc},
 created = {2017-03-24T14:12:26.193Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:26.193Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {Synthesis and characterization of a new Pt(II)-mimosine complex are described. Elemental, mass spectrometry and thermal analyses for the complex are consistent with the formula [PtCl2(C8H10N2O4)]center dot 1.5H(2)O. C-13 NMR, N-15 NMR and infrared spectroscopy indicate coordination of the ligand to Pt(II) through the N and O atoms in a square-planar geometry. The final residue after thermal treatment was identified as metallic Pt. The complex is soluble in dimethylsulfoxide.},
 bibtype = {article},
 author = {Corbi, PP Pedro P. and Massabni, Antonio C. AC and Costa-Neto, Claudio M. CM},
 doi = {10.1080/00958970500236209},
 journal = {Journal of Coordination Chemistry},
 number = {16},
 keywords = {Infrared spectroscopy,L-mimosine,N-15 NMR,N-Acetyl-L-cysteine,Platinum(II),Solid-state NMR,Thermal analysis,amino acids,metal complex}
}

Synthesis and characterization of a new Pt(II)-mimosine complex are described. Elemental, mass spectrometry and thermal analyses for the complex are consistent with the formula [PtCl2(C8H10N2O4)]center dot 1.5H(2)O. C-13 NMR, N-15 NMR and infrared spectroscopy indicate coordination of the ligand to Pt(II) through the N and O atoms in a square-planar geometry. The final residue after thermal treatment was identified as metallic Pt. The complex is soluble in dimethylsulfoxide.

@article{
 title = {Competition Between Humic Substances and α-Amino Acids by Metal Species},
 type = {article},
 year = {2004},
 keywords = {alpha-amino acids,humic substances,metals,soils},
 pages = {437-440},
 volume = {15},
 month = {6},
 id = {297a0c12-3615-332d-84dd-9634de9769c8},
 created = {2017-03-24T14:12:22.807Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:22.807Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {The aim of the present work was to carry out experimental comparison between humic substances (HS) and representative alpha-amino acids ( methionine, methionine sulfoxide and cysteine hydrochloride) in relation to the complexation of biologically active trace elements (Al, Cu, Pb, Mn, Zn, Cd and Ni). A mobile time-controlled tangential-flow UF technique was applied to differentiate between HS-metal and alpha-aminoacids-metal complexes. Metal determinations were conventionally carried out using a ICP-OES. The results showed that HS may be considered as a selective complexing agents with higher metal bonding capability in relation to Al, Cu and Pb, the fact that may be clinically important.},
 bibtype = {article},
 author = {Santos, Ademir dos and Bellin, Iramaia C and Corbi, Pedro Paulo and Cuin, Alexandre and Rosa, Andre Henrique and Rezende, Maria Olimpia de O and Rocha, Julio Cesar and Melnikov, Petr},
 journal = {Journal Of Brazil Chemical Society},
 number = {3}
}

The aim of the present work was to carry out experimental comparison between humic substances (HS) and representative alpha-amino acids ( methionine, methionine sulfoxide and cysteine hydrochloride) in relation to the complexation of biologically active trace elements (Al, Cu, Pb, Mn, Zn, Cd and Ni). A mobile time-controlled tangential-flow UF technique was applied to differentiate between HS-metal and alpha-aminoacids-metal complexes. Metal determinations were conventionally carried out using a ICP-OES. The results showed that HS may be considered as a selective complexing agents with higher metal bonding capability in relation to Al, Cu and Pb, the fact that may be clinically important.

@misc{
 title = {Composto de paládio com desoxialiina, processo de preparação deste composto e agente com atividade antiproliferativa e citotóxica sobre células tumorais, obtido a partir do composto},
 type = {misc},
 year = {2004},
 month = {11},
 publisher = {Instituto Nacional de Propriedade Industrial (INPI)},
 id = {c5578fe2-57d4-3091-8262-c62f54899381},
 created = {2017-03-24T14:12:25.094Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:25.094Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 language = {por},
 private_publication = {false},
 abstract = {Processo: PI0300583-6},
 bibtype = {misc},
 author = {Massabni, Antonio Carlos [UNESP] and Corbi, Pedro Paulo and Costa Neto, Claudio Miguel da and Moreira, Andreia Galdin}
}

Processo: PI0300583-6

@misc{
 title = {Composto de paládio com desoxialiina, processo de preparação deste composto e agente com atividade antiproliferativa e citotóxica sobre células tumorais, obtido a partir do composto, PI0300583-6},
 type = {misc},
 year = {2004},
 websites = {http://base.repositorio.unesp.br/handle/11449/108975},
 month = {2},
 day = {12},
 id = {7249dd17-f1f6-3c41-bf91-92b729825a50},
 created = {2017-03-24T14:12:25.936Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-04-06T15:58:06.231Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 source_type = {PAT},
 private_publication = {false},
 bibtype = {misc},
 author = {Massabni, Carlos Antonio and Corbi, Paulo Pedro and Costa Neto, da Claudio Miguel and Moreira, Galdin Andreia}
}

@article{
 title = {Molecular mechanisms of N -acetylcysteine actions},
 type = {article},
 year = {2003},
 keywords = {X-ray,amino acids,powder diffraction,thiazolidine-4-carboxylic acid},
 pages = {6-20},
 volume = {60},
 websites = {http://link.springer.com/10.1007/s000180300001},
 month = {1},
 publisher = {Cambridge University Press},
 day = {1},
 id = {86dc9d0f-0900-3340-afd5-2700ebdef744},
 created = {2017-04-06T15:49:48.287Z},
 accessed = {2017-04-06},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T19:26:49.898Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 bibtype = {article},
 author = {Zafarullah, M. and Li, W. Q. and Sylvester, J. and Ahmad, M.},
 doi = {10.1007/s000180300001},
 journal = {Cellular and Molecular Life Sciences (CMLS)},
 number = {1}
}

@article{
 title = {Physicochemical Properties of Sildenafil Citrate (Viagra) and Sildenafil Base},
 type = {article},
 year = {2003},
 pages = {2140-2143},
 volume = {92},
 websites = {http://www.sciencedirect.com/science/article/pii/S0022354916313235},
 id = {4265d53d-8dde-3aaf-a192-1f3a494246d3},
 created = {2017-04-06T15:53:05.581Z},
 accessed = {2017-04-06},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-04-06T15:53:05.581Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {Sildenafil citrate (Viagra) [I] and sildenafil base [II] are easily and unequivocally characterized by a set of physicochemical methods that include X‐ray diffractometry, infrared spectroscopy, and thermal analysis. Monoclinic lattice constants: [I]: a = 26.98 Å; b = 11.95 Å; c = 16.68 Å; β = 106.97°. [II]: a = 8.66 Å; b = 34.27 Å; c = 8.93 Å; β = 96.63°. Both compounds decompose at 189.4°C [I] and 251.9°C [II]. Densities and refractive indices are given. © 2003 Wiley‐Liss, Inc. and the American Pharmacists Association J Pharm Sci 92:2140–2143, 2003},
 bibtype = {article},
 author = {Melnikov, Petr and Corbi, Pedro P. and Cuin, Alexandre and Cavicchioli, Mauricio and Guimarães, Wellington R.},
 doi = {10.1002/jps.10469},
 journal = {Journal of Pharmaceutical Sciences},
 number = {10}
}

Sildenafil citrate (Viagra) [I] and sildenafil base [II] are easily and unequivocally characterized by a set of physicochemical methods that include X‐ray diffractometry, infrared spectroscopy, and thermal analysis. Monoclinic lattice constants: [I]: a = 26.98 Å; b = 11.95 Å; c = 16.68 Å; β = 106.97°. [II]: a = 8.66 Å; b = 34.27 Å; c = 8.93 Å; β = 96.63°. Both compounds decompose at 189.4°C [I] and 251.9°C [II]. Densities and refractive indices are given. © 2003 Wiley‐Liss, Inc. and the American Pharmacists Association J Pharm Sci 92:2140–2143, 2003

@inproceedings{
 title = {X-ray and Mossbauer study of mixed potassium-sodium ferrate (VI)},
 type = {inproceedings},
 year = {2002},
 pages = {277-280},
 publisher = {SPRINGER},
 city = {PO BOX 17, 3300 AA DORDRECHT, NETHERLANDS},
 id = {f4a99206-05ee-3f65-94dd-60266cb88e16},
 created = {2017-03-24T14:12:26.000Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:26.000Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {Mixed potassium-sodium ferrate(VI), K3Na(FeO4)(2) has been synthesised by precipitation from alkaline solution. It crystallise in a hexagonal system with lattice parameters a=5,8273+/-0.0018 Angstrom, c=7.5415+/-0.0032 Angstrom and belongs to glaserite-like structures (space group P/3m1). Iron is present in oxidation state +6: room temperature Mossbauer spectrum is a doublet with isomer shift delta=-0.89+/-0.01 mm.s(-1) (relative to alpha-iron), quadrupole splitting Delta=0.21+/-0.01 mm.s(-1) and full width at half-height Gamma=0.22+/-0.01 mm.s(-1).},
 bibtype = {inproceedings},
 author = {Dedushenko, SK and Perfiliev, YD and Golubev, AM and Melnikov, P and Corbi, PP and Saprykin, AA},
 editor = {Thomas, MF and Williams, JM and Gibb, TC}
}

Mixed potassium-sodium ferrate(VI), K3Na(FeO4)(2) has been synthesised by precipitation from alkaline solution. It crystallise in a hexagonal system with lattice parameters a=5,8273+/-0.0018 Angstrom, c=7.5415+/-0.0032 Angstrom and belongs to glaserite-like structures (space group P/3m1). Iron is present in oxidation state +6: room temperature Mossbauer spectrum is a doublet with isomer shift delta=-0.89+/-0.01 mm.s(-1) (relative to alpha-iron), quadrupole splitting Delta=0.21+/-0.01 mm.s(-1) and full width at half-height Gamma=0.22+/-0.01 mm.s(-1).

@article{
 title = {Synthesis, characterization and thermal behavior of complexes of copper(II), zinc(II) and cadmium(II) with S,S '-methylenebis(cysteine)},
 type = {article},
 year = {2001},
 pages = {337},
 volume = {86},
 month = {8},
 id = {b190d146-e938-34db-9c42-32df387cc7fe},
 created = {2017-03-24T14:12:24.262Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:24.262Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {Synthesis and characterization, including data on thermal decomposition, are reported for the complexes of S,S'-methylenebis(cysteine) (djenkolic acid) with copper(II), zinc(II) and cadmium(II): CuC(7)H(12)N(2)O(4)S(2) [I]; ZnC(7)H(12)N(2)O(4)S(2) [II] and CdC(7)H(12)N(2)O(4)S(2) [III] X-ray diffraction showed that the compounds are isostructural and belong to a monoclinic system. According to IR spectra, COO, NH(2) groups and bridging sulfur atoms are the main coordination sites.},
 bibtype = {article},
 author = {Melnikov, P and Cavicchioli, M and Corbi, P P and al, et},
 journal = {Journal of Inorganic Biochemistry},
 number = {1},
 keywords = {S,S `-methylenebis(cysteine),complexes,djenkolic acid,transition metals}
}

Synthesis and characterization, including data on thermal decomposition, are reported for the complexes of S,S'-methylenebis(cysteine) (djenkolic acid) with copper(II), zinc(II) and cadmium(II): CuC(7)H(12)N(2)O(4)S(2) [I]; ZnC(7)H(12)N(2)O(4)S(2) [II] and CdC(7)H(12)N(2)O(4)S(2) [III] X-ray diffraction showed that the compounds are isostructural and belong to a monoclinic system. According to IR spectra, COO, NH(2) groups and bridging sulfur atoms are the main coordination sites.

@article{
 title = {Powder X-Ray characterization of sildenafil base},
 type = {article},
 year = {2001},
 pages = {337},
 volume = {86},
 month = {8},
 id = {f3f5ffa2-b669-38b1-9f48-4fe814be4133},
 created = {2017-03-24T14:12:24.333Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:24.333Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 bibtype = {article},
 author = {Melnikov, P and Cavicchioli, M and Corbi, P P and al, et},
 journal = {Journal of Inorganic Biochemistry},
 number = {1}
}

@article{
 title = {Powder X-ray characterization of djenkolic acid},
 type = {article},
 year = {2001},
 pages = {46-47},
 volume = {16},
 month = {3},
 id = {ba8eadf2-3a1c-3abe-8439-5049e16cf90a},
 created = {2017-03-24T14:12:26.714Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:26.714Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {X-ray powder diffraction data for the orthorhombic natural amino acid djenkolic acid, C7H14N2O4S2, is described in this paper. The orthorhombic cell parameters are: a = 8.12 Angstrom, b = 12.16 Angstrom, and c = 5.38 Angstrom . (C) 2001 International Centre for Diffraction Data.},
 bibtype = {article},
 author = {Melnikov, P and Cuin, A and Corbi, PP and Cavicchioli, M and Massabni, AC},
 doi = {10.1154/1.1348002},
 journal = {Powder Diffraction},
 number = {1},
 keywords = {amino acids,djenkolic acid,powder diffraction}
}

X-ray powder diffraction data for the orthorhombic natural amino acid djenkolic acid, C7H14N2O4S2, is described in this paper. The orthorhombic cell parameters are: a = 8.12 Angstrom, b = 12.16 Angstrom, and c = 5.38 Angstrom . (C) 2001 International Centre for Diffraction Data.

@article{
 title = {Synthesis and characterization of a cobalt(II) complex with methionine sulfoxide},
 type = {article},
 year = {2001},
 pages = {185},
 volume = {86},
 month = {8},
 id = {773e77cc-76ce-317e-9d14-9359f4524037},
 created = {2017-03-24T14:12:26.942Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:26.942Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 bibtype = {article},
 author = {Corbi, PP and Melnikov, P and Massabni, AC},
 journal = {Journal of Inorganic Biochemistry},
 number = {1}
}

@article{
 title = {Cobalt(II) and nickel(II) complexes with djenkolic acid},
 type = {article},
 year = {2000},
 pages = {28-31},
 volume = {26},
 month = {1},
 id = {f1866320-fffd-3fc9-a676-0d705289d85a},
 created = {2017-03-24T14:12:24.546Z},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2017-03-24T14:12:24.546Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 language = {English},
 private_publication = {false},
 abstract = {Cobalt(II) and nickel(II) djenkolates CoC7H12N2O4S2. H2O (I) and NiC7H12N2O4S2. H2O (II) were synthesized by the reaction of potassium djenkolate with the respective chlorides. LR spectra suggested coordination via the COO- and NH2 groups for the ligands in both compounds. Visible absorption spectra confirmed the octahedral structure of the complexes. X-ray powder diffraction patterns were indexed in the orthorhombic and monoclinic unit cells with parameters: a = 11.35, b = 7.35, c = 6.85 Angstrom for I and a = 11.54, b = 7.45, c = 6.90 Angstrom, beta = 94.95 degrees for II.},
 bibtype = {article},
 author = {Corbi, P P and Cavicchioli, M and Mel'Nikov, P and al, et},
 journal = {Russian Journal of Coordination Chemistry}
}

Cobalt(II) and nickel(II) djenkolates CoC7H12N2O4S2. H2O (I) and NiC7H12N2O4S2. H2O (II) were synthesized by the reaction of potassium djenkolate with the respective chlorides. LR spectra suggested coordination via the COO- and NH2 groups for the ligands in both compounds. Visible absorption spectra confirmed the octahedral structure of the complexes. X-ray powder diffraction patterns were indexed in the orthorhombic and monoclinic unit cells with parameters: a = 11.35, b = 7.35, c = 6.85 Angstrom for I and a = 11.54, b = 7.45, c = 6.90 Angstrom, beta = 94.95 degrees for II.

@article{
 title = {A solid nickel(II) complex with methionine sulfoxide},
 type = {article},
 year = {2000},
 pages = {153-157},
 volume = {308},
 websites = {http://www.sciencedirect.com/science/article/pii/S0925838800010227,http://linkinghub.elsevier.com/retrieve/pii/S0925838800010227},
 month = {8},
 id = {333006d4-7031-3fd4-899e-9266281c48a0},
 created = {2017-04-06T15:54:47.320Z},
 accessed = {2017-04-06},
 file_attached = {false},
 profile_id = {12b9f049-9566-3679-935b-c90c226950d2},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2018-10-26T19:26:49.901Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {Solid Ni(C5H10NO3S)2·2H2O complex was prepared and characterized. Electronic absorption spectrum shows an octahedral geometry for the complex. Infrared spectroscopy analysis shows that the metal atom is coordinated to the ligand through (COO−) and (S=O) groups. Thermal analysis confirmed the composition of the complex and suggests that the water molecules are not coordinated to the metal ion. The complex shows extremely high solubility in water.},
 bibtype = {article},
 author = {Corbi, Pedro P and Melnikov, Petr and Massabni, Antonio C},
 doi = {10.1016/S0925-8388(00)01022-7},
 journal = {Journal of Alloys and Compounds},
 number = {1-2}
}

Solid Ni(C5H10NO3S)2·2H2O complex was prepared and characterized. Electronic absorption spectrum shows an octahedral geometry for the complex. Infrared spectroscopy analysis shows that the metal atom is coordinated to the ligand through (COO−) and (S=O) groups. Thermal analysis confirmed the composition of the complex and suggests that the water molecules are not coordinated to the metal ion. The complex shows extremely high solubility in water.

@article{
 title = {Silver Sulfadiazine: Effect on the Ultrastructure of Pseudomonas aeruginosa},
 type = {article},
 year = {1973},
 pages = {621-624},
 volume = {3},
 websites = {https://journals.asm.org/doi/10.1128/AAC.3.5.621},
 id = {c077e203-1de1-3074-a276-18d1a477e478},
 created = {2022-12-21T18:20:52.998Z},
 accessed = {2022-11-09},
 file_attached = {false},
 profile_id = {9a2b34ac-8c18-3784-982f-470861446144},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2022-12-21T18:20:52.998Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {Pseudomonas aeruginosa exposed to silver sulfadiazine (AgSu) were examined in an electron microscope. The treated cells were distorted in shape, and structures (blebs) protruded from the cell surfa...},
 bibtype = {article},
 author = {Coward, J. E. and Carr, H. S. and Rosenkranz, H. S.},
 doi = {10.1128/AAC.3.5.621},
 journal = {Antimicrobial Agents and Chemotherapy},
 number = {5}
}

Pseudomonas aeruginosa exposed to silver sulfadiazine (AgSu) were examined in an electron microscope. The treated cells were distorted in shape, and structures (blebs) protruded from the cell surfa...

@article{
 title = {Silver Sulfadiazine: Effect on the Growth and Ultrastructure of Staphylococci},
 type = {article},
 year = {1973},
 keywords = {245666,Antibacterial,Chemotherapy 1973,No. 6,Sensitivity,Silver sulfadiazine,Staphylococci,Vol. 19},
 pages = {348-353},
 volume = {19},
 websites = {https://www.karger.com/Article/FullText/221475,https://www.karger.com/Article/Abstract/221475},
 publisher = {Karger Publishers},
 id = {b3b7d238-47b7-3cbe-9828-30afee22bd8a},
 created = {2022-12-21T18:20:52.999Z},
 accessed = {2022-11-09},
 file_attached = {false},
 profile_id = {9a2b34ac-8c18-3784-982f-470861446144},
 group_id = {90e2c5d9-8e7e-3658-9751-f62154fc0a37},
 last_modified = {2022-12-21T18:20:52.999Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 private_publication = {false},
 abstract = {Clinical isolates of Staphylococcus aureus and S. epidermidis were sensitive to levels of silver sulfadiazine (AgSu) that can readily be achieved topically. As a species, S. epidermidis isolates were sensitive to lower levels of AgSu than S. aureus strains. There was no correlation between sensitivity to AgSu and sensitivity or resistance to other antimicrobial agents. Many of the strains tested were multiply-resistant to a number of antibiotics. Significantly, there was no relationship between sensitivity to AgSu and to sulfadiazine (sodium). AgSu-treated Staphylococcí became enlarged and exhibited retraction of the cytoplasmic membrane from the cell wall. Division planes between bacteria became indistinct. It is concluded that in Staphylococcí AgSu acts at the external cell structures.},
 bibtype = {article},
 author = {Coward, Joe E. and Carr, Howard S. and Rosenkranz, Herbert S.},
 doi = {10.1159/000221475},
 journal = {Chemotherapy},
 number = {6}
}

Clinical isolates of Staphylococcus aureus and S. epidermidis were sensitive to levels of silver sulfadiazine (AgSu) that can readily be achieved topically. As a species, S. epidermidis isolates were sensitive to lower levels of AgSu than S. aureus strains. There was no correlation between sensitivity to AgSu and sensitivity or resistance to other antimicrobial agents. Many of the strains tested were multiply-resistant to a number of antibiotics. Significantly, there was no relationship between sensitivity to AgSu and to sulfadiazine (sodium). AgSu-treated Staphylococcí became enlarged and exhibited retraction of the cytoplasmic membrane from the cell wall. Division planes between bacteria became indistinct. It is concluded that in Staphylococcí AgSu acts at the external cell structures.