BibBase https://github.com/salkmanorlab/manor_publications/raw/main/manorlab

2025 (11)

Astrocyte glypican 5 regulates synapse maturation and stabilization. Bosworth, A. P, Contreras, M., Sancho, L., Salas, I. H, Paumier, A., Novak, S. W., Manor, U., & Allen, N. J Cell reports, 44(3). 2025.
link bibtex

@article{bosworth2025astrocyte,
  title={Astrocyte glypican 5 regulates synapse maturation and stabilization},
  author={Bosworth, Alexandra P and Contreras, Minerva and Sancho, Laura and Salas, Isabel H and Paumier, Adrien and Novak, Sammy Weiser and Manor, Uri and Allen, Nicola J},
  journal={Cell reports},
  volume={44},
  number={3},
  year={2025},
  publisher={Elsevier}
}

Mitochondria-and ER-associated actin are required for mitochondrial fusion. Gatti, P., Schiavon, C., Cicero, J., Manor, U., & Germain, M. Nature Communications, 16(1): 451. 2025.
link bibtex

@article{gatti2025mitochondria,
  title={Mitochondria-and ER-associated actin are required for mitochondrial fusion},
  author={Gatti, Priya and Schiavon, Cara and Cicero, Julien and Manor, Uri and Germain, Marc},
  journal={Nature Communications},
  volume={16},
  number={1},
  pages={451},
  year={2025},
  publisher={Nature Publishing Group UK London}
}

Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain. Wang, M., Zhang, L., Novak, S. W., Yu, J., Gallina, I. S, Xu, L. L, Lim, C. K, Fernandes, S., Shokhirev, M. N, Williams, A. E, & others Nature Biotechnology, 43(1): 52–62. 2025.
link bibtex

@article{wang2025morphological,
  title={Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain},
  author={Wang, Meiyan and Zhang, Lei and Novak, Sammy Weiser and Yu, Jingting and Gallina, Iryna S and Xu, Lynne L and Lim, Christina K and Fernandes, Sarah and Shokhirev, Maxim N and Williams, April E and others},
  journal={Nature Biotechnology},
  volume={43},
  number={1},
  pages={52--62},
  year={2025},
  publisher={Nature Publishing Group US New York}
}

PSSR2: a user-friendly Python package for democratizing deep learning-based point-scanning super-resolution microscopy. Stites, H. C, & Manor, U. BMC Methods, 2(1): 1. 2025.
link bibtex

@article{stites2025pssr2,
  title={PSSR2: a user-friendly Python package for democratizing deep learning-based point-scanning super-resolution microscopy},
  author={Stites, Hayden C and Manor, Uri},
  journal={BMC Methods},
  volume={2},
  number={1},
  pages={1},
  year={2025},
  publisher={BioMed Central London}
}

VASCilia (Vision Analysis StereoCilia): A Napari Plugin for Deep Learning-Based 3D Analysis of Cochlear Hair Cell Stereocilia Bundles. Kassim, Y. M, Rosenberg, D. B, Das, S., Huang, Z., Rahman, S., Al Shammaa, I., Salim, S., Huang, K., Renero, A., Miller, C., & others bioRxiv,2024–06. 2025.
link bibtex

@article{kassim2025vascilia,
  title={VASCilia (Vision Analysis StereoCilia): A Napari Plugin for Deep Learning-Based 3D Analysis of Cochlear Hair Cell Stereocilia Bundles},
  author={Kassim, Yasmin M and Rosenberg, David B and Das, Samprita and Huang, Zhuoling and Rahman, Samia and Al Shammaa, Ibraheem and Salim, Samer and Huang, Kevin and Renero, Alma and Miller, Cayla and others},
  journal={bioRxiv},
  pages={2024--06},
  year={2025}
}

An Open-Source Deep Learning-Based GUI Toolbox For Automated Auditory Brainstem Response Analyses (ABRA). Erra, A., Chen, J., Miller, C. M, Chrysostomou, E., Barret, S., Kassim, Y. M, Friedman, R. A, Lauer, A., Ceriani, F., Marcotti, W., & others bioRxiv,2024–06. 2025.
link bibtex

@article{erra2025open,
  title={An Open-Source Deep Learning-Based GUI Toolbox For Automated Auditory Brainstem Response Analyses (ABRA)},
  author={Erra, Abhijeeth and Chen, Jeffrey and Miller, Cayla M and Chrysostomou, Elena and Barret, Shannon and Kassim, Yasmin M and Friedman, Rick A and Lauer, Amanda and Ceriani, Federico and Marcotti, Walter and others},
  journal={bioRxiv},
  pages={2024--06},
  year={2025}
}

Beyond static snapshots: Mitochondria in action. Cicero, J., & Manor, U. Current Opinion in Cell Biology, 92: 102460. 2025.
link bibtex

@article{cicero2025beyond,
  title={Beyond static snapshots: Mitochondria in action},
  author={Cicero, Julien and Manor, Uri},
  journal={Current Opinion in Cell Biology},
  volume={92},
  pages={102460},
  year={2025},
  publisher={Elsevier Current Trends}
}

Psychoplastogens for treating hearing-related disorders. Olson, D. E, & MANOR, U. February 20 2025. US Patent App. 18/720,410
link bibtex

@misc{olson2025psychoplastogens,
  title={Psychoplastogens for treating hearing-related disorders},
  author={Olson, David E and MANOR, Uri},
  year={2025},
  month=feb # "~20",
  note={US Patent App. 18/720,410}
}

Pcdh20 is a POU2F3 target gene required for proper tuft cell microvillus formation. Ankenbauer, K. E, Yang, Y., Chung, C., Andrade, L. R, Weiser Novak, S., Jarvis, B., Ali Hanel, W. H, Liu, J., Sarkisian, V., Dani, N., & others bioRxiv,2025–03. 2025.
link bibtex

@article{ankenbauer2025pcdh20,
  title={Pcdh20 is a POU2F3 target gene required for proper tuft cell microvillus formation},
  author={Ankenbauer, Katherine E and Yang, Yilin and Chung, Chi-Yeh and Andrade, Leonardo R and Weiser Novak, Sammy and Jarvis, Brenda and Ali Hanel, Wahida H and Liu, Jiayue and Sarkisian, Victoria and Dani, Neil and others},
  journal={bioRxiv},
  pages={2025--03},
  year={2025},
  publisher={Cold Spring Harbor Laboratory}
}

Molecular design of a therapeutic LSD analogue with reduced hallucinogenic potential. Tuck, J. R, Dunlap, L. E, Khatib, Y. A, Hatzipantelis, C. J, Weiser Novak, S., Rahn, R. M, Davis, A. R, Mosswood, A., Vernier, A. M., Fenton, E. M, & others Proceedings of the National Academy of Sciences, 122(16): e2416106122. 2025.
link bibtex

@article{tuck2025molecular,
  title={Molecular design of a therapeutic LSD analogue with reduced hallucinogenic potential},
  author={Tuck, Jeremy R and Dunlap, Lee E and Khatib, Yara A and Hatzipantelis, Cassandra J and Weiser Novak, Sammy and Rahn, Rachel M and Davis, Alexis R and Mosswood, Adam and Vernier, Anna MM and Fenton, Ethan M and others},
  journal={Proceedings of the National Academy of Sciences},
  volume={122},
  number={16},
  pages={e2416106122},
  year={2025},
  publisher={National Academy of Sciences}
}

Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress. Rhine, K., Li, R., Kopalle, H. M, Rothamel, K., Ge, X., Epstein, E., Mizrahi, O., Madrigal, A. A, Her, H., Gomberg, T. A, & others Nature Neuroscience,1–11. 2025.
link bibtex

@article{rhine2025neuronal,
  title={Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress},
  author={Rhine, Kevin and Li, Rachel and Kopalle, Hema M and Rothamel, Katherine and Ge, Xuezhen and Epstein, Elle and Mizrahi, Orel and Madrigal, Assael A and Her, Hsuan-Lin and Gomberg, Trent A and others},
  journal={Nature Neuroscience},
  pages={1--11},
  year={2025},
  publisher={Nature Publishing Group}
}

2024 (12)

Content-aware frame interpolation (CAFI): deep learning-based temporal super-resolution for fast bioimaging. Priessner, M., Gaboriau, D. C., Sheridan, A., Lenn, T., Garzon-Coral, C., Dunn, A. R, Chubb, J. R, Tousley, A. M, Majzner, R. G, Manor, U., & others Nature Methods, 21(2): 322–330. 2024.
link bibtex

@article{priessner2024content,
  title={Content-aware frame interpolation (CAFI): deep learning-based temporal super-resolution for fast bioimaging},
  author={Priessner, Martin and Gaboriau, David CA and Sheridan, Arlo and Lenn, Tchern and Garzon-Coral, Carlos and Dunn, Alexander R and Chubb, Jonathan R and Tousley, Aidan M and Majzner, Robbie G and Manor, Uri and others},
  journal={Nature Methods},
  volume={21},
  number={2},
  pages={322--330},
  year={2024},
  publisher={Nature Publishing Group US New York}
}

Altered Fhod3 expression involved in progressive high-frequency hearing loss via dysregulation of actin polymerization stoichiometry in the cuticular plate. Boussaty, E. C., Ninoyu, Y., Andrade, L. R, Li, Q., Takeya, R., Sumimoto, H., Ohyama, T., Wahlin, K. J, Manor, U., & Friedman, R. A PLoS genetics, 20(3): e1011211. 2024.
link bibtex

@article{boussaty2024altered,
  title={Altered Fhod3 expression involved in progressive high-frequency hearing loss via dysregulation of actin polymerization stoichiometry in the cuticular plate},
  author={Boussaty, Ely Cheikh and Ninoyu, Yuzuru and Andrade, Leonardo R and Li, Qingzhong and Takeya, Ryu and Sumimoto, Hideki and Ohyama, Takahiro and Wahlin, Karl J and Manor, Uri and Friedman, Rick A},
  journal={PLoS genetics},
  volume={20},
  number={3},
  pages={e1011211},
  year={2024},
  publisher={Public Library of Science San Francisco, CA USA}
}

Large-scale annotated dataset for cochlear hair cell detection and classification. Buswinka, C. J, Rosenberg, D. B, Simikyan, R. G, Osgood, R. T, Fernandez, K., Nitta, H., Hayashi, Y., Liberman, L. W, Nguyen, E., Yildiz, E., & others Scientific data, 11(1): 416. 2024.
link bibtex

@article{buswinka2024large,
  title={Large-scale annotated dataset for cochlear hair cell detection and classification},
  author={Buswinka, Christopher J and Rosenberg, David B and Simikyan, Rubina G and Osgood, Richard T and Fernandez, Katharine and Nitta, Hidetomi and Hayashi, Yushi and Liberman, Leslie W and Nguyen, Emily and Yildiz, Erdem and others},
  journal={Scientific data},
  volume={11},
  number={1},
  pages={416},
  year={2024},
  publisher={Nature Publishing Group UK London}
}

Oligodendrocyte calcium signaling promotes actin-dependent myelin sheath extension. Iyer, M., Kantarci, H., Cooper, M. H, Ambiel, N., Novak, S. W., Andrade, L. R, Lam, M., Jones, G., Münch, A. E, Yu, X., & others Nature communications, 15(1): 265. 2024.
link bibtex

@article{iyer2024oligodendrocyte,
  title={Oligodendrocyte calcium signaling promotes actin-dependent myelin sheath extension},
  author={Iyer, Manasi and Kantarci, Husniye and Cooper, Madeline H and Ambiel, Nicholas and Novak, Sammy Weiser and Andrade, Leonardo R and Lam, Mable and Jones, Graham and M{\"u}nch, Alexandra E and Yu, Xinzhu and others},
  journal={Nature communications},
  volume={15},
  number={1},
  pages={265},
  year={2024},
  publisher={Nature Publishing Group UK London}
}

Mitochondrial DNA replication stress triggers a pro-inflammatory endosomal pathway of nucleoid disposal. Newman, L. E, Weiser Novak, S., Rojas, G. R, Tadepalle, N., Schiavon, C. R, Grotjahn, D. A, Towers, C. G, Tremblay, M., Donnelly, M. P, Ghosh, S., & others Nature cell biology, 26(2): 194–206. 2024.
link bibtex

@article{newman2024mitochondrial,
  title={Mitochondrial DNA replication stress triggers a pro-inflammatory endosomal pathway of nucleoid disposal},
  author={Newman, Laura E and Weiser Novak, Sammy and Rojas, Gladys R and Tadepalle, Nimesha and Schiavon, Cara R and Grotjahn, Danielle A and Towers, Christina G and Tremblay, Marie-{\`E}ve and Donnelly, Matthew P and Ghosh, Sagnika and others},
  journal={Nature cell biology},
  volume={26},
  number={2},
  pages={194--206},
  year={2024},
  publisher={Nature Publishing Group UK London}
}

Early-Onset Hearing Loss in Mouse Models of Alzheimer’s Disease and Increased DNA Damage in the Cochlea. Park, J., Sahbaz, B. D., Pekhale, K., Chu, X., Okur, M. N, Grati, M., Isgrig, K., Chien, W., Chrysostomou, E., Sullivan, L., & others Aging Biology, 1: 20240025. 2024.
link bibtex

@article{park2024early,
  title={Early-Onset Hearing Loss in Mouse Models of Alzheimer’s Disease and Increased DNA Damage in the Cochlea},
  author={Park, Jae-Hyeon and Sahbaz, Burcin Duan and Pekhale, Komal and Chu, Xixia and Okur, Mustafa N and Grati, Mhamed and Isgrig, Kevin and Chien, Wade and Chrysostomou, Elena and Sullivan, Lauren and others},
  journal={Aging Biology},
  volume={1},
  pages={20240025},
  year={2024}
}

INF2-mediated actin polymerization at ER-organelle contacts regulates organelle size and movement. Schiavon, C. R, Wang, Y., Feng, J. W, Garrett, S., Sung, T., Dayn, Y., Wang, C., Youle, R. J, Quintero-Carmona, O. A, Shadel, G. S, & others bioRxiv. 2024.
link bibtex

@article{schiavon2024inf2,
  title={INF2-mediated actin polymerization at ER-organelle contacts regulates organelle size and movement},
  author={Schiavon, Cara R and Wang, Yuning and Feng, Jasmine W and Garrett, Stephanie and Sung, Tsung-Chang and Dayn, Yelena and Wang, Chunxin and Youle, Richard J and Quintero-Carmona, Omar A and Shadel, Gerald S and others},
  journal={bioRxiv},
  year={2024}
}

Marmoset cognitive aging: Heterogeneity and synaptic dysfunction. Glavis-Bloom, C., Vanderlip, C. R, Asch, P. A, Novak, S. P W., Kuwajima, M., Kirk, L. M, Harris, K. M, Manor, U., & Reynolds, J. H Alzheimer's & Dementia, 20: e085459. 2024.
link bibtex

@article{glavis2024marmoset,
  title={Marmoset cognitive aging: Heterogeneity and synaptic dysfunction},
  author={Glavis-Bloom, Courtney and Vanderlip, Casey R and Asch, Payton A and Novak, Sammy P Weiser and Kuwajima, Masaaki and Kirk, Lyndsey M and Harris, Kristen M and Manor, Uri and Reynolds, John H},
  journal={Alzheimer's \& Dementia},
  volume={20},
  pages={e085459},
  year={2024}
}

Dark Microglia Are Abundant in Normal Postnatal Development, where they Remodel Synapses via Phagocytosis and Trogocytosis, and Are Dependent on TREM2. Vecchiarelli, H. A, Bisht, K., Sharma, K., Weiser Novak, S., Traetta, M. E, Garcia-Segura, M. E., St-Pierre, M., Savage, J. C, Willis, C., Picard, K., & others bioRxiv,2024–10. 2024.
link bibtex

@article{vecchiarelli2024dark,
  title={Dark Microglia Are Abundant in Normal Postnatal Development, where they Remodel Synapses via Phagocytosis and Trogocytosis, and Are Dependent on TREM2},
  author={Vecchiarelli, Haley A and Bisht, Kanchan and Sharma, Kaushik and Weiser Novak, Sammy and Traetta, Marianela E and Garcia-Segura, Monica Emili and St-Pierre, Marie-Kim and Savage, Julie C and Willis, Cory and Picard, Katherine and others},
  journal={bioRxiv},
  pages={2024--10},
  year={2024},
  publisher={Cold Spring Harbor Laboratory}
}

Inhibition of RNA splicing triggers CHMP7 nuclear entry, impacting TDP-43 function and leading to the onset of ALS cellular phenotypes. Al-Azzam, N., To, J. H, Gautam, V., Street, L. A, Nguyen, C. B, Naritomi, J. T, Lam, D. C, Madrigal, A. A, Lee, B., Jin, W., & others Neuron, 112(24): 4033–4047. 2024.
link bibtex

@article{al2024inhibition,
  title={Inhibition of RNA splicing triggers CHMP7 nuclear entry, impacting TDP-43 function and leading to the onset of ALS cellular phenotypes},
  author={Al-Azzam, Norah and To, Jenny H and Gautam, Vaishali and Street, Lena A and Nguyen, Chloe B and Naritomi, Jack T and Lam, Dylan C and Madrigal, Assael A and Lee, Benjamin and Jin, Wenhao and others},
  journal={Neuron},
  volume={112},
  number={24},
  pages={4033--4047},
  year={2024},
  publisher={Elsevier}
}

Sparse Annotation is Sufficient for Bootstrapping Dense Segmentation. Thiyagarajan, V. V., Sheridan, A., Harris, K. M, & Manor, U. bioRxiv. 2024.
link bibtex

@article{thiyagarajan2024sparse,
  title={Sparse Annotation is Sufficient for Bootstrapping Dense Segmentation},
  author={Thiyagarajan, Vijay Venu and Sheridan, Arlo and Harris, Kristen M and Manor, Uri},
  journal={bioRxiv},
  year={2024}
}

Gene therapy for hearing loss: challenges and the promise of cellular plasticity and epigenetic modulation. Das, S., & Manor, U. Frontiers in Neurology, 15: 1511938. 2024.
link bibtex

@article{das2024gene,
  title={Gene therapy for hearing loss: challenges and the promise of cellular plasticity and epigenetic modulation},
  author={Das, Samprita and Manor, Uri},
  journal={Frontiers in Neurology},
  volume={15},
  pages={1511938},
  year={2024},
  publisher={Frontiers Media SA}
}

2023 (16)

Local shape descriptors for neuron segmentation. Sheridan, A., Nguyen, T. M, Deb, D., Lee, W. A., Saalfeld, S., Turaga, S. C, Manor, U., & Funke, J. Nature methods, 20(2): 295–303. 2023.
link bibtex

@article{sheridan2023local,
  title={Local shape descriptors for neuron segmentation},
  author={Sheridan, Arlo and Nguyen, Tri M and Deb, Diptodip and Lee, Wei-Chung Allen and Saalfeld, Stephan and Turaga, Srinivas C and Manor, Uri and Funke, Jan},
  journal={Nature methods},
  volume={20},
  number={2},
  pages={295--303},
  year={2023},
  publisher={Nature Publishing Group US New York}
}

Obstructive Sleep Apnea–induced Endothelial Dysfunction Is Mediated by miR-210. Shang, F., Wang, S., Gongol, B., Han, S. Y., Cho, Y., Schiavon, C. R, Chen, L., Xing, Y., Zhao, Y., Ning, M., & others American Journal of Respiratory and Critical Care Medicine, 207(3): 323–335. 2023.
link bibtex

@article{shang2023obstructive,
  title={Obstructive Sleep Apnea--induced Endothelial Dysfunction Is Mediated by miR-210},
  author={Shang, Fenqing and Wang, Shen-Chih and Gongol, Brendoan and Han, So Yun and Cho, Yoshitake and Schiavon, Cara R and Chen, Lili and Xing, Yuanming and Zhao, Yingshuai and Ning, Ming’an and others},
  journal={American Journal of Respiratory and Critical Care Medicine},
  volume={207},
  number={3},
  pages={323--335},
  year={2023},
  publisher={American Thoracic Society}
}

Violation of the ultrastructural size principle in the dorsolateral prefrontal cortex underlies working memory impairment in the aged common marmoset (Callithrix jacchus). Glavis-Bloom, C., Vanderlip, C. R, Weiser Novak, S., Kuwajima, M., Kirk, L., Harris, K. M, Manor, U., & Reynolds, J. H Frontiers in Aging Neuroscience, 15: 1146245. 2023.
link bibtex

@article{glavis2023violation,
  title={Violation of the ultrastructural size principle in the dorsolateral prefrontal cortex underlies working memory impairment in the aged common marmoset (Callithrix jacchus)},
  author={Glavis-Bloom, Courtney and Vanderlip, Casey R and Weiser Novak, Sammy and Kuwajima, Masaaki and Kirk, Lyndsey and Harris, Kristen M and Manor, Uri and Reynolds, John H},
  journal={Frontiers in Aging Neuroscience},
  volume={15},
  pages={1146245},
  year={2023},
  publisher={Frontiers Media SA}
}

Mutant Prion Protein Endoggresomes are Hubs for Local Axonal Organelle-Cytoskeletal Remodeling. Chaiamarit, T., Verhelle, A., Chassefeyre, R., Shukla, N., Novak, S. W., Andrade, L. R, Manor, U., & Encalada, S. E bioRxiv,2023–03. 2023.
link bibtex 1 download

@article{chaiamarit2023mutant,
  title={Mutant Prion Protein Endoggresomes are Hubs for Local Axonal Organelle-Cytoskeletal Remodeling},
  author={Chaiamarit, Tai and Verhelle, Adriaan and Chassefeyre, Romain and Shukla, Nandini and Novak, Sammy Weiser and Andrade, Leonardo R and Manor, Uri and Encalada, Sandra E},
  journal={bioRxiv},
  pages={2023--03},
  year={2023},
  publisher={Cold Spring Harbor Laboratory}
}

Biomonitoring and precision health in deep space supported by artificial intelligence. Scott, R. T, Sanders, L. M, Antonsen, E. L, Hastings, J. J., Park, S., Mackintosh, G., Reynolds, R. J, Hoarfrost, A. L, Sawyer, A., Greene, C. S, & others Nature Machine Intelligence, 5(3): 196–207. 2023.
link bibtex

@article{scott2023biomonitoring,
  title={Biomonitoring and precision health in deep space supported by artificial intelligence},
  author={Scott, Ryan T and Sanders, Lauren M and Antonsen, Erik L and Hastings, Jaden JA and Park, Seung-min and Mackintosh, Graham and Reynolds, Robert J and Hoarfrost, Adrienne L and Sawyer, Aenor and Greene, Casey S and others},
  journal={Nature Machine Intelligence},
  volume={5},
  number={3},
  pages={196--207},
  year={2023},
  publisher={Nature Publishing Group UK London}
}

Biological research and self-driving labs in deep space supported by artificial intelligence. Sanders, L. M, Scott, R. T, Yang, J. H, Qutub, A. A., Garcia Martin, H., Berrios, D. C, Hastings, J. J., Rask, J., Mackintosh, G., Hoarfrost, A. L, & others Nature Machine Intelligence, 5(3): 208–219. 2023.
link bibtex

@article{sanders2023biological,
  title={Biological research and self-driving labs in deep space supported by artificial intelligence},
  author={Sanders, Lauren M and Scott, Ryan T and Yang, Jason H and Qutub, Amina Ann and Garcia Martin, Hector and Berrios, Daniel C and Hastings, Jaden JA and Rask, Jon and Mackintosh, Graham and Hoarfrost, Adrienne L and others},
  journal={Nature Machine Intelligence},
  volume={5},
  number={3},
  pages={208--219},
  year={2023},
  publisher={Nature Publishing Group UK London}
}

Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1. Malik, N., Ferreira, B. I, Hollstein, P. E, Curtis, S. D, Trefts, E., Weiser Novak, S., Yu, J., Gilson, R., Hellberg, K., Fang, L., & others Science, 380(6642): eabj5559. 2023.
link bibtex

@article{malik2023induction,
  title={Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1},
  author={Malik, Nazma and Ferreira, Bibiana I and Hollstein, Pablo E and Curtis, Stephanie D and Trefts, Elijah and Weiser Novak, Sammy and Yu, Jingting and Gilson, Rebecca and Hellberg, Kristina and Fang, Lingjing and others},
  journal={Science},
  volume={380},
  number={6642},
  pages={eabj5559},
  year={2023},
  publisher={American Association for the Advancement of Science}
}

Attenuation of age-related hearing impairment in senescence-accelerated mouse prone 8 (SAMP8) mice treated with fatty acid synthase inhibitor CMS121. Pham, T. B, Boussaty, E. C., Currais, A., Maher, P., Schubert, D. R, Manor, U., & Friedman, R. A Journal of Molecular Neuroscience, 73(4): 307–315. 2023.
link bibtex 3 downloads

@article{pham2023attenuation,
  title={Attenuation of age-related hearing impairment in senescence-accelerated mouse prone 8 (SAMP8) mice treated with fatty acid synthase inhibitor CMS121},
  author={Pham, Tammy B and Boussaty, Ely Cheikh and Currais, Antonio and Maher, Pamela and Schubert, David R and Manor, Uri and Friedman, Rick A},
  journal={Journal of Molecular Neuroscience},
  volume={73},
  number={4},
  pages={307--315},
  year={2023},
  publisher={Springer US New York}
}

Roadmap on deep learning for microscopy. Volpe, G., Wählby, C., Tian, L., Hecht, M., Yakimovich, A., Monakhova, K., Waller, L., Sbalzarini, I. F, Metzler, C. A, Xie, M., & others ArXiv,arXiv–2303. 2023.
link bibtex

@article{volpe2023roadmap,
  title={Roadmap on deep learning for microscopy},
  author={Volpe, Giovanni and W{\"a}hlby, Carolina and Tian, Lei and Hecht, Michael and Yakimovich, Artur and Monakhova, Kristina and Waller, Laura and Sbalzarini, Ivo F and Metzler, Christopher A and Xie, Mingyang and others},
  journal={ArXiv},
  pages={arXiv--2303},
  year={2023}
}

Cochlear transcriptome analysis of an outbred mouse population (CFW). Boussaty, E. C., Tedeschi, N., Novotny, M., Ninoyu, Y., Du, E., Draf, C., Zhang, Y., Manor, U., Scheuermann, R. H, & Friedman, R. Frontiers in Cellular Neuroscience, 17: 1256619. 2023.
link bibtex

@article{boussaty2023cochlear,
  title={Cochlear transcriptome analysis of an outbred mouse population (CFW)},
  author={Boussaty, Ely Cheikh and Tedeschi, Neil and Novotny, Mark and Ninoyu, Yuzuru and Du, Eric and Draf, Clara and Zhang, Yun and Manor, Uri and Scheuermann, Richard H and Friedman, Rick},
  journal={Frontiers in Cellular Neuroscience},
  volume={17},
  pages={1256619},
  year={2023},
  publisher={Frontiers Media SA}
}

Long-term NAD+ supplementation prevents the progression of age-related hearing loss in mice. Okur, M. N., Sahbaz, B. D., Kimura, R., Manor, U., Patel, J., Park, J., Andrade, L., Puligilla, C., Croteau, D. L., & Bohr, V. A. Aging Cell,1474–9718. 2023.
link bibtex

@article{okur2023long,
  title={Long-term NAD+ supplementation prevents the progression of age-related hearing loss in mice},
  author={Okur, Mustafa N. and Sahbaz, Burcin Duan and Kimura, Risako and Manor, Uri and Patel, Jaimin and Park, Jae-Hyeon and Andrade, Leo and Puligilla, Chandrakalap and Croteau, Deborah L. and Bohr, Vilhelm A.},
  journal={Aging Cell},
  pages={1474--9718},
  year={2023}
}

NGLY1 mutations cause protein aggregation in human neurons. Manole, A., Wong, T., Rhee, A., Novak, S., Chin, S., Tsimring, K., Paucar, A., Williams, A., Newmeyer, T. F., Schafer, S. T, & others Cell reports, 42(12). 2023.
link bibtex

@article{manole2023ngly1,
  title={NGLY1 mutations cause protein aggregation in human neurons},
  author={Manole, Andreea and Wong, Thomas and Rhee, Amanda and Novak, Sammy and Chin, Shao-Ming and Tsimring, Katya and Paucar, Andres and Williams, April and Newmeyer, Traci Fang and Schafer, Simon T and others},
  journal={Cell reports},
  volume={42},
  number={12},
  year={2023},
  publisher={Elsevier}
}

Myelin accuracy requires calcium-regulated actin steering. Iyer, M, Kantarci, H, Ambiel, N, Novak, S., Andrade, L, Lam, M, Yu, X, Khakh, B, Manor, U, & Zuchero, B In GLIA, volume 71, pages E63–E63, 2023. WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
link bibtex

@inproceedings{iyer2023myelin,
  title={Myelin accuracy requires calcium-regulated actin steering},
  author={Iyer, M and Kantarci, H and Ambiel, N and Novak, SW and Andrade, L and Lam, M and Yu, X and Khakh, B and Manor, U and Zuchero, B},
  booktitle={GLIA},
  volume={71},
  pages={E63--E63},
  year={2023},
  organization={WILEY 111 RIVER ST, HOBOKEN 07030-5774, NJ USA}
}

Opinions on imaging and cutting-edge developments in light microscopy for biomedical applications. Prakash, K., Heintzmann, R., Manor, U., & Smith, C. Applied Physics Letters, 123(26). 2023.
link bibtex

@article{prakash2023opinions,
  title={Opinions on imaging and cutting-edge developments in light microscopy for biomedical applications},
  author={Prakash, Kirti and Heintzmann, Rainer and Manor, Uri and Smith, Carlas},
  journal={Applied Physics Letters},
  volume={123},
  number={26},
  year={2023},
  publisher={AIP Publishing}
}

Endolysosomal pathways in the formation of toxic protein aggregates in axons: mechanisms of neurodegeneration and strategies to restore neuronal function. Chassefeyre, R, Chaiamarit, T, Verhelle, A, Noval, S W., Andrade, L, Manor, U, & Encalada, S In MOLECULAR BIOLOGY OF THE CELL, volume 34, pages 139–139, 2023. AMER SOC CELL BIOLOGY 8120 WOODMONT AVE, STE 750, BETHESDA, MD 20814-2755 USA
link bibtex

@inproceedings{chassefeyre2023endolysosomal,
  title={Endolysosomal pathways in the formation of toxic protein aggregates in axons: mechanisms of neurodegeneration and strategies to restore neuronal function},
  author={Chassefeyre, R and Chaiamarit, T and Verhelle, A and Noval, S Weiser and Andrade, L and Manor, U and Encalada, S},
  booktitle={MOLECULAR BIOLOGY OF THE CELL},
  volume={34},
  number={2},
  pages={139--139},
  year={2023},
  organization={AMER SOC CELL BIOLOGY 8120 WOODMONT AVE, STE 750, BETHESDA, MD 20814-2755 USA}
}

INF2 Regulates Organelle Motility via ER-associated Actin. Schiavon, C., Wang, Y, Manole, A, Sung, T., Dayn, Y, Latour, P, Echaniz-Laguna, A, Shy, M., Zuchero, B., Shadel, G., & others In MOLECULAR BIOLOGY OF THE CELL, volume 34, pages 311–312, 2023. AMER SOC CELL BIOLOGY 8120 WOODMONT AVE, STE 750, BETHESDA, MD 20814-2755 USA
link bibtex

@inproceedings{schiavon2023inf2,
  title={INF2 Regulates Organelle Motility via ER-associated Actin},
  author={Schiavon, CR and Wang, Y and Manole, A and Sung, T-C and Dayn, Y and Latour, P and Echaniz-Laguna, A and Shy, ME and Zuchero, BJ and Shadel, GS and others},
  booktitle={MOLECULAR BIOLOGY OF THE CELL},
  volume={34},
  number={2},
  pages={311--312},
  year={2023},
  organization={AMER SOC CELL BIOLOGY 8120 WOODMONT AVE, STE 750, BETHESDA, MD 20814-2755 USA}
}

2022 (8)

Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury. Ma, Z., Lytle, N. K, Chen, B., Jyotsana, N., Novak, S. W., Cho, C. J, Caplan, L., Ben-Levy, O., Neininger, A. C, Burnette, D. T, & others Gastroenterology, 162(2): 604–620. 2022.
link bibtex

@article{ma2022single,
  title={Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury},
  author={Ma, Zhibo and Lytle, Nikki K and Chen, Bob and Jyotsana, Nidhi and Novak, Sammy Weiser and Cho, Charles J and Caplan, Leah and Ben-Levy, Olivia and Neininger, Abigail C and Burnette, Dylan T and others},
  journal={Gastroenterology},
  volume={162},
  number={2},
  pages={604--620},
  year={2022},
  publisher={WB Saunders}
}

INF2-mediated actin filament reorganization confers intrinsic resilience to neuronal ischemic injury. Calabrese, B., Jones, S. L, Shiraishi-Yamaguchi, Y., Lingelbach, M., Manor, U., Svitkina, T. M, Higgs, H. N, Shih, A. Y, & Halpain, S. Nature communications, 13(1): 6037. 2022.
link bibtex

@article{calabrese2022inf2,
  title={INF2-mediated actin filament reorganization confers intrinsic resilience to neuronal ischemic injury},
  author={Calabrese, Barbara and Jones, Steven L and Shiraishi-Yamaguchi, Yoko and Lingelbach, Michael and Manor, Uri and Svitkina, Tatyana M and Higgs, Henry N and Shih, Andy Y and Halpain, Shelley},
  journal={Nature communications},
  volume={13},
  number={1},
  pages={6037},
  year={2022},
  publisher={Nature Publishing Group UK London}
}

A Nesprin-4/kinesin-1 cargo model for nuclear positioning in cochlear outer hair cells. Taiber, S., Gozlan, O., Cohen, R., Andrade, L. R, Gregory, E. F, Starr, D. A, Moran, Y., Hipp, R., Kelley, M. W, Manor, U., & others Frontiers in Cell and Developmental Biology, 10: 974168. 2022.
link bibtex 1 download

@article{taiber2022nesprin,
  title={A Nesprin-4/kinesin-1 cargo model for nuclear positioning in cochlear outer hair cells},
  author={Taiber, Shahar and Gozlan, Oren and Cohen, Roie and Andrade, Leonardo R and Gregory, Ellen F and Starr, Daniel A and Moran, Yehu and Hipp, Rebecca and Kelley, Matthew W and Manor, Uri and others},
  journal={Frontiers in Cell and Developmental Biology},
  volume={10},
  pages={974168},
  year={2022},
  publisher={Frontiers Media SA}
}

Metaplasia-induced Epithelial Heterogeneity Directs Pancreatic Injury and Tumorigenesis. DelGiorno, K., Ma, Z., Lytle, N., Chen, B., Jyotsana, N., Weiser Novak, S., Cho, C., Caplan, L., Ben-Levy, O., Neininger, A., & others The FASEB Journal, 36. 2022.
link bibtex 1 download

@article{delgiorno2022metaplasia,
  title={Metaplasia-induced Epithelial Heterogeneity Directs Pancreatic Injury and Tumorigenesis},
  author={DelGiorno, Kathleen and Ma, Zhibo and Lytle, Nikki and Chen, Bob and Jyotsana, Nidhi and Weiser Novak, Sammy and Cho, Charles and Caplan, Leah and Ben-Levy, Olivia and Neininger, Abigail and others},
  journal={The FASEB Journal},
  volume={36},
  year={2022},
  publisher={The Federation of American Societies for Experimental Biology}
}

Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3. Ramirez, M. A, Ninoyu, Y., Miller, C., Andrade, L. R, Edassery, S., Bomba-Warczak, E., Ortega, B., Manor, U., Rutherford, M. A, Friedman, R. A, & others IScience, 25(8). 2022.
link bibtex

@article{ramirez2022cochlear,
  title={Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3},
  author={Ramirez, Miguel A and Ninoyu, Yuzuru and Miller, Cayla and Andrade, Leonardo R and Edassery, Seby and Bomba-Warczak, Ewa and Ortega, Briana and Manor, Uri and Rutherford, Mark A and Friedman, Rick A and others},
  journal={IScience},
  volume={25},
  number={8},
  year={2022},
  publisher={Elsevier}
}

AAV-mediated rescue of Eps8 expression in vivo restores hair-cell function in a mouse model of recessive deafness. Jeng, J., Carlton, A. J, Goodyear, R. J, Chinowsky, C., Ceriani, F., Johnson, S. L, Sung, T., Dayn, Y., Richardson, G. P, Bowl, M. R, & others Molecular Therapy Methods & Clinical Development, 26: 355–370. 2022.
link bibtex

@article{jeng2022aav,
  title={AAV-mediated rescue of Eps8 expression in vivo restores hair-cell function in a mouse model of recessive deafness},
  author={Jeng, Jing-Yi and Carlton, Adam J and Goodyear, Richard J and Chinowsky, Colbie and Ceriani, Federico and Johnson, Stuart L and Sung, Tsung-Chang and Dayn, Yelena and Richardson, Guy P and Bowl, Michael R and others},
  journal={Molecular Therapy Methods \& Clinical Development},
  volume={26},
  pages={355--370},
  year={2022},
  publisher={Elsevier}
}

Exploring the role of image domain in self-supervised DNN models of rodent brains. Prasad, A., Manor, U., & Pereira, T. In SVRHM 2022 Workshop@ NeurIPS, 2022.
link bibtex

@inproceedings{prasad2022exploring,
  title={Exploring the role of image domain in self-supervised DNN models of rodent brains},
  author={Prasad, Aaditya and Manor, Uri and Pereira, Talmo},
  booktitle={SVRHM 2022 Workshop@ NeurIPS},
  year={2022}
}

Researchers who reach far beyond their disabilities. Marx, V. 2022.
link bibtex

@misc{marx2022researchers,
  title={Researchers who reach far beyond their disabilities},
  author={Marx, Vivien},
  journal={Nature Methods},
  volume={19},
  number={12},
  pages={1512--1512},
  year={2022},
  publisher={NATURE PORTFOLIO HEIDELBERGER PLATZ 3, BERLIN, 14197, GERMANY}
}

2021 (8)

Impaired mitochondrial mobility in Charcot-Marie-Tooth disease. Schiavon, C. R, Shadel, G. S, & Manor, U. Frontiers in Cell and Developmental Biology, 9: 624823. 2021.
link bibtex

@article{schiavon2021impaired,
  title={Impaired mitochondrial mobility in Charcot-Marie-Tooth disease},
  author={Schiavon, Cara R and Shadel, Gerald S and Manor, Uri},
  journal={Frontiers in Cell and Developmental Biology},
  volume={9},
  pages={624823},
  year={2021},
  publisher={Frontiers Media SA}
}

Dynamic regulation of CTCF stability and sub-nuclear localization in response to stress. Lehman, B. J, Lopez-Diaz, F. J, Santisakultarm, T. P, Fang, L., Shokhirev, M. N, Diffenderfer, K. E, Manor, U., & Emerson, B. M PLoS genetics, 17(1): e1009277. 2021.
link bibtex

@article{lehman2021dynamic,
  title={Dynamic regulation of CTCF stability and sub-nuclear localization in response to stress},
  author={Lehman, Bettina J and Lopez-Diaz, Fernando J and Santisakultarm, Thom P and Fang, Linjing and Shokhirev, Maxim N and Diffenderfer, Kenneth E and Manor, Uri and Emerson, Beverly M},
  journal={PLoS genetics},
  volume={17},
  number={1},
  pages={e1009277},
  year={2021},
  publisher={Public Library of Science San Francisco, CA USA}
}

Deep learning-based point-scanning super-resolution imaging. Fang, L., Monroe, F., Novak, S. W., Kirk, L., Schiavon, C. R, Yu, S. B, Zhang, T., Wu, M., Kastner, K., Latif, A. A., & others Nature methods, 18(4): 406–416. 2021.
link bibtex

@article{fang2021deep,
  title={Deep learning-based point-scanning super-resolution imaging},
  author={Fang, Linjing and Monroe, Fred and Novak, Sammy Weiser and Kirk, Lyndsey and Schiavon, Cara R and Yu, Seungyoon B and Zhang, Tong and Wu, Melissa and Kastner, Kyle and Latif, Alaa Abdel and others},
  journal={Nature methods},
  volume={18},
  number={4},
  pages={406--416},
  year={2021},
  publisher={Nature Publishing Group US New York}
}

SARS-CoV-2 spike protein impairs endothelial function via downregulation of ACE 2. Lei, Y., Zhang, J., Schiavon, C. R, He, M., Chen, L., Shen, H., Zhang, Y., Yin, Q., Cho, Y., Andrade, L., & others Circulation research, 128(9): 1323–1326. 2021.
link bibtex

@article{lei2021sars,
  title={SARS-CoV-2 spike protein impairs endothelial function via downregulation of ACE 2},
  author={Lei, Yuyang and Zhang, Jiao and Schiavon, Cara R and He, Ming and Chen, Lili and Shen, Hui and Zhang, Yichi and Yin, Qian and Cho, Yoshitake and Andrade, Leonardo and others},
  journal={Circulation research},
  volume={128},
  number={9},
  pages={1323--1326},
  year={2021},
  publisher={Lippincott Williams \& Wilkins Hagerstown, MD}
}

The San Diego Nathan shock center: tackling the heterogeneity of aging. Shadel, G. S, Adams, P. D, Berggren, W T., Diedrich, J. K, Diffenderfer, K. E, Gage, F. H, Hah, N., Hansen, M., Hetzer, M. W, Molina, A. J., & others Geroscience, 43(5): 2139–2148. 2021.
link bibtex

@article{shadel2021san,
  title={The San Diego Nathan shock center: tackling the heterogeneity of aging},
  author={Shadel, Gerald S and Adams, Peter D and Berggren, W Travis and Diedrich, Jolene K and Diffenderfer, Kenneth E and Gage, Fred H and Hah, Nasun and Hansen, Malene and Hetzer, Martin W and Molina, Anthony JA and others},
  journal={Geroscience},
  volume={43},
  number={5},
  pages={2139--2148},
  year={2021},
  publisher={Springer International Publishing Cham}
}

SARS-COV-2 SPIKE PROTEIN IMPAIRMENT OF ENDOTHELIAL FUNCTION DOES NOT IMPACT VACCINE SAFETY. Manor, U., & Howard, J. P . 2021.
link bibtex

@article{manor2021sars,
  title={SARS-COV-2 SPIKE PROTEIN IMPAIRMENT OF ENDOTHELIAL FUNCTION DOES NOT IMPACT VACCINE SAFETY},
  author={Manor, Uri and Howard, Jeremy P},
  year={2021},
  publisher={Zenodo}
}

Endosomal sorting drives the formation of axonal prion protein endoggresomes. Chassefeyre, R., Chaiamarit, T., Verhelle, A., Novak, S. W., Andrade, L. R, Leitão, A. D., Manor, U., & Encalada, S. E Science Advances, 7(52): eabg3693. 2021.
link bibtex

@article{chassefeyre2021endosomal,
  title={Endosomal sorting drives the formation of axonal prion protein endoggresomes},
  author={Chassefeyre, Romain and Chaiamarit, Tai and Verhelle, Adriaan and Novak, Sammy Weiser and Andrade, Leonardo R and Leit{\~a}o, Andr{\'e} DG and Manor, Uri and Encalada, Sandra E},
  journal={Science Advances},
  volume={7},
  number={52},
  pages={eabg3693},
  year={2021},
  publisher={American Association for the Advancement of Science}
}

Biologists need modern data infrastructure on campus. Andreev, A., Morrell, T., Briney, K., Gesing, S., & Manor, U. arXiv preprint arXiv:2108.07631. 2021.
link bibtex

@article{andreev2021biologists,
  title={Biologists need modern data infrastructure on campus},
  author={Andreev, Andrey and Morrell, Tom and Briney, Kristin and Gesing, Sandra and Manor, Uri},
  journal={arXiv preprint arXiv:2108.07631},
  year={2021}
}

2020 (8)

Actin chromobody imaging reveals sub-organellar actin dynamics. Schiavon, C. R, Zhang, T., Zhao, B., Moore, A. S, Wales, P., Andrade, L. R, Wu, M., Sung, T., Dayn, Y., Feng, J. W, & others Nature methods, 17(9): 917–921. 2020.
link bibtex 3 downloads

@article{schiavon2020actin,
  title={Actin chromobody imaging reveals sub-organellar actin dynamics},
  author={Schiavon, Cara R and Zhang, Tong and Zhao, Bing and Moore, Andrew S and Wales, Pauline and Andrade, Leonardo R and Wu, Melissa and Sung, Tsung-Chang and Dayn, Yelena and Feng, Jasmine W and others},
  journal={Nature methods},
  volume={17},
  number={9},
  pages={917--921},
  year={2020},
  publisher={Nature Publishing Group US New York}
}

Organelle–Organelle Contacts: Origins and Functions. Manor, U. The Liver: Biology and Pathobiology,151–159. 2020.
link bibtex

@article{manor2020organelle,
  title={Organelle--Organelle Contacts: Origins and Functions},
  author={Manor, Uri},
  journal={The Liver: Biology and Pathobiology},
  pages={151--159},
  year={2020},
  publisher={John Wiley \& Sons, Ltd Chichester, UK}
}

Tuft cell formation reflects epithelial plasticity in pancreatic injury: implications for modeling human pancreatitis. DelGiorno, K. E, Naeem, R. F, Fang, L., Chung, C., Ramos, C., Luhtala, N., O’Connor, C., Hunter, T., Manor, U., & Wahl, G. M Frontiers in physiology, 11: 88. 2020.
link bibtex

@article{delgiorno2020tuft,
  title={Tuft cell formation reflects epithelial plasticity in pancreatic injury: implications for modeling human pancreatitis},
  author={DelGiorno, Kathleen E and Naeem, Razia F and Fang, Linjing and Chung, Chi-Yeh and Ramos, Cynthia and Luhtala, Natalie and O’Connor, Carolyn and Hunter, Tony and Manor, Uri and Wahl, Geoffrey M},
  journal={Frontiers in physiology},
  volume={11},
  pages={88},
  year={2020},
  publisher={Frontiers Media SA}
}

Cysteine depletion induces pancreatic tumor ferroptosis in mice. Badgley, M. A, Kremer, D. M, Maurer, H C., DelGiorno, K. E, Lee, H., Purohit, V., Sagalovskiy, I. R, Ma, A., Kapilian, J., Firl, C. E., & others Science, 368(6486): 85–89. 2020.
link bibtex

@article{badgley2020cysteine,
  title={Cysteine depletion induces pancreatic tumor ferroptosis in mice},
  author={Badgley, Michael A and Kremer, Daniel M and Maurer, H Carlo and DelGiorno, Kathleen E and Lee, Ho-Joon and Purohit, Vinee and Sagalovskiy, Irina R and Ma, Alice and Kapilian, Jonathan and Firl, Christina EM and others},
  journal={Science},
  volume={368},
  number={6486},
  pages={85--89},
  year={2020},
  publisher={American Association for the Advancement of Science}
}

Tuft cells inhibit pancreatic tumorigenesis in mice by producing prostaglandin D2. DelGiorno, K. E, Chung, C., Vavinskaya, V., Maurer, H C., Novak, S. W., Lytle, N. K, Ma, Z., Giraddi, R. R, Wang, D., Fang, L., & others Gastroenterology, 159(5): 1866–1881. 2020.
link bibtex

@article{delgiorno2020tuft,
  title={Tuft cells inhibit pancreatic tumorigenesis in mice by producing prostaglandin D2},
  author={DelGiorno, Kathleen E and Chung, Chi-Yeh and Vavinskaya, Vera and Maurer, H Carlo and Novak, Sammy Weiser and Lytle, Nikki K and Ma, Zhibo and Giraddi, Rajshekhar R and Wang, Dezhen and Fang, Linjing and others},
  journal={Gastroenterology},
  volume={159},
  number={5},
  pages={1866--1881},
  year={2020},
  publisher={WB Saunders}
}

The genetics of variation of the wave 1 amplitude of the mouse auditory brainstem response. Boussaty, E. C., Gillard, D., Lavinsky, J., Salehi, P., Wang, J., Mendonça, A., Allayee, H., Manor, U., & Friedman, R. A. Journal of the Association for Research in Otolaryngology, 21: 323–336. 2020.
link bibtex

@article{boussaty2020genetics,
  title={The genetics of variation of the wave 1 amplitude of the mouse auditory brainstem response},
  author={Boussaty, Ely Cheikh and Gillard, Danielle and Lavinsky, Joel and Salehi, Pezhman and Wang, Juemei and Mendon{\c{c}}a, Aline and Allayee, Hooman and Manor, Uri and Friedman, Rick Adam},
  journal={Journal of the Association for Research in Otolaryngology},
  volume={21},
  pages={323--336},
  year={2020},
  publisher={Springer US}
}

Auxin-induced signaling protein nanoclustering contributes to cell polarity formation. Pan, X., Fang, L., Liu, J., Senay-Aras, B., Lin, W., Zheng, S., Zhang, T., Guo, J., Manor, U., Van Norman, J., & others Nature Communications, 11(1): 3914. 2020.
link bibtex

@article{pan2020auxin,
  title={Auxin-induced signaling protein nanoclustering contributes to cell polarity formation},
  author={Pan, Xue and Fang, Linjing and Liu, Jianfeng and Senay-Aras, Betul and Lin, Wenwei and Zheng, Shuan and Zhang, Tong and Guo, Jingzhe and Manor, Uri and Van Norman, Jaimie and others},
  journal={Nature Communications},
  volume={11},
  number={1},
  pages={3914},
  year={2020},
  publisher={Nature Publishing Group UK London}
}

Uri Manor. Marx, V. Nature Methods, 17(9): 865–866. 2020.
link bibtex

@article{marx2020uri,
  title={Uri Manor.},
  author={Marx, Vivien},
  journal={Nature Methods},
  volume={17},
  number={9},
  pages={865--866},
  year={2020},
  publisher={Nature Publishing Group}
}

2019 (6)

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring. Shi, Y., Gao, W., Lytle, N. K, Huang, P., Yuan, X., Dann, A. M, Ridinger-Saison, M., DelGiorno, K. E, Antal, C. E, Liang, G., & others Nature, 569(7754): 131–135. 2019.
link bibtex

@article{shi2019targeting,
  title={Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring},
  author={Shi, Yu and Gao, Weina and Lytle, Nikki K and Huang, Peiwu and Yuan, Xiao and Dann, Amanda M and Ridinger-Saison, Maya and DelGiorno, Kathleen E and Antal, Corina E and Liang, Gaoyang and others},
  journal={Nature},
  volume={569},
  number={7754},
  pages={131--135},
  year={2019},
  publisher={Nature Publishing Group UK London}
}

A novel role for Myosin-Va in mitochondrial fission. Araujo, J. S, Silva-Junior, R. M., Zhang, T., Schiavon, C. R, Chu, Q., Wu, M., Pontes, C. L., Souza, A. O, Alberici, L. C, Santos, A. M, & others BioRxiv,655803. 2019.
link bibtex

@article{araujo2019novel,
  title={A novel role for Myosin-Va in mitochondrial fission},
  author={Araujo, Jackeline S and Silva-Junior, Rui MP and Zhang, Tong and Schiavon, Cara R and Chu, Qian and Wu, Melissa and Pontes, Carmen LS and Souza, Anderson O and Alberici, Luciane C and Santos, Aline M and others},
  journal={BioRxiv},
  pages={655803},
  year={2019},
  publisher={Cold Spring Harbor Laboratory}
}

Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption. Villanueva, J. E, Livelo, C., Trujillo, A. S, Chandran, S., Woodworth, B., Andrade, L., Le, H. D, Manor, U., Panda, S., & Melkani, G. C Nature communications, 10(1): 2700. 2019.
link bibtex

@article{villanueva2019time,
  title={Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption},
  author={Villanueva, Jes{\'u}s E and Livelo, Christopher and Trujillo, Adriana S and Chandran, Sahaana and Woodworth, Brendon and Andrade, Leo and Le, Hiep D and Manor, Uri and Panda, Satchidananda and Melkani, Girish C},
  journal={Nature communications},
  volume={10},
  number={1},
  pages={2700},
  year={2019},
  publisher={Nature Publishing Group UK London}
}

Regulation of the ER stress response by a mitochondrial microprotein. Chu, Q., Martinez, T. F, Novak, S. W., Donaldson, C. J, Tan, D., Vaughan, J. M, Chang, T., Diedrich, J. K, Andrade, L., Kim, A., & others Nature communications, 10(1): 4883. 2019.
link bibtex

@article{chu2019regulation,
  title={Regulation of the ER stress response by a mitochondrial microprotein},
  author={Chu, Qian and Martinez, Thomas F and Novak, Sammy Weiser and Donaldson, Cynthia J and Tan, Dan and Vaughan, Joan M and Chang, Tina and Diedrich, Jolene K and Andrade, Leo and Kim, Andrew and others},
  journal={Nature communications},
  volume={10},
  number={1},
  pages={4883},
  year={2019},
  publisher={Nature Publishing Group UK London}
}

Pancreatic tumorigenesis evokes mechanisms of tissue injury and repair. DelGiorno, K. E, Chung, C., Giraddi, R., Ke, E., Maurer, H C., Ridinger-Saison, M., Ali, W. H, Tsui, C., Ramos, C., Naeem, R., & others Cancer Research, 79(13_Supplement): 5169–5169. 2019.
link bibtex

@article{delgiorno2019pancreatic,
  title={Pancreatic tumorigenesis evokes mechanisms of tissue injury and repair},
  author={DelGiorno, Kathleen E and Chung, Chi-Yeh and Giraddi, Raj and Ke, Eugene and Maurer, H Carlo and Ridinger-Saison, Maya and Ali, Wahida H and Tsui, Crystal and Ramos, Cynthia and Naeem, Razia and others},
  journal={Cancer Research},
  volume={79},
  number={13\_Supplement},
  pages={5169--5169},
  year={2019},
  publisher={The American Association for Cancer Research}
}

Decrappification, deoldification, and super resolution. Antic, J., Howard, J., & Manor, U. In Facebook f8 conference, pages 1, 2019.
link bibtex

@inproceedings{antic2019decrappification,
  title={Decrappification, deoldification, and super resolution},
  author={Antic, Jason and Howard, Jeremy and Manor, Uri},
  booktitle={Facebook f8 conference},
  pages={1},
  year={2019}
}

2018 (1)

FanStore: Enabling efficient and scalable I/O for distributed deep learning. Zhang, Z., Huang, L., Manor, U., Fang, L., Merlo, G., Michoski, C., Cazes, J., & Gaffney, N. arXiv preprint arXiv:1809.10799. 2018.
link bibtex

@article{zhang2018fanstore,
  title={FanStore: Enabling efficient and scalable I/O for distributed deep learning},
  author={Zhang, Zhao and Huang, Lei and Manor, Uri and Fang, Linjing and Merlo, Gabriele and Michoski, Craig and Cazes, John and Gaffney, Niall},
  journal={arXiv preprint arXiv:1809.10799},
  year={2018}
}

2017 (3)

Sonic hedgehog pathway activation increases mitochondrial abundance and activity in hippocampal neurons. Yao, P. J, Manor, U., Petralia, R. S, Brose, R. D, Wu, R. T., Ott, C., Wang, Y., Charnoff, A., Lippincott-Schwartz, J., & Mattson, M. P Molecular Biology of the Cell, 28(3): 387–395. 2017.
link bibtex

@article{yao2017sonic,
  title={Sonic hedgehog pathway activation increases mitochondrial abundance and activity in hippocampal neurons},
  author={Yao, Pamela J and Manor, Uri and Petralia, Ronald S and Brose, Rebecca D and Wu, Ryan TY and Ott, Carolyn and Wang, Ya-Xian and Charnoff, Ari and Lippincott-Schwartz, Jennifer and Mattson, Mark P},
  journal={Molecular Biology of the Cell},
  volume={28},
  number={3},
  pages={387--395},
  year={2017},
  publisher={The American Society for Cell Biology}
}

Actin cytoskeleton-mediated constriction of membrane organelles via endoplasmic reticulum scaffolding. Curchoe, C. L., & Manor, U. ACS biomaterials science & engineering, 3(11): 2727–2732. 2017.
link bibtex

@article{curchoe2017actin,
  title={Actin cytoskeleton-mediated constriction of membrane organelles via endoplasmic reticulum scaffolding},
  author={Curchoe, Carol Lynn and Manor, Uri},
  journal={ACS biomaterials science \& engineering},
  volume={3},
  number={11},
  pages={2727--2732},
  year={2017},
  publisher={American Chemical Society}
}

In vivo ribbon mobility and turnover of ribeye at zebrafish hair cell synapses. Graydon, C. W, Manor, U., & Kindt, K. S Scientific Reports, 7(1): 7467. 2017.
link bibtex

@article{graydon2017vivo,
  title={In vivo ribbon mobility and turnover of ribeye at zebrafish hair cell synapses},
  author={Graydon, Cole W and Manor, Uri and Kindt, Katie S},
  journal={Scientific Reports},
  volume={7},
  number={1},
  pages={7467},
  year={2017},
  publisher={Nature Publishing Group UK London}
}

2016 (2)

Intravital imaging reveals ghost fibers as architectural units guiding myogenic progenitors during regeneration. Webster, M. T, Manor, U., Lippincott-Schwartz, J., & Fan, C. Cell stem cell, 18(2): 243–252. 2016.
link bibtex

@article{webster2016intravital,
  title={Intravital imaging reveals ghost fibers as architectural units guiding myogenic progenitors during regeneration},
  author={Webster, Micah T and Manor, Uri and Lippincott-Schwartz, Jennifer and Fan, Chen-Ming},
  journal={Cell stem cell},
  volume={18},
  number={2},
  pages={243--252},
  year={2016},
  publisher={Elsevier}
}

Tectorins crosslink type II collagen fibrils and connect the tectorial membrane to the spiral limbus. Andrade, L. R, Salles, F. T, Grati, M., Manor, U., & Kachar, B. Journal of structural biology, 194(2): 139–146. 2016.
link bibtex

@article{andrade2016tectorins,
  title={Tectorins crosslink type II collagen fibrils and connect the tectorial membrane to the spiral limbus},
  author={Andrade, Leonardo R and Salles, Felipe T and Grati, M’hamed and Manor, Uri and Kachar, Bechara},
  journal={Journal of structural biology},
  volume={194},
  number={2},
  pages={139--146},
  year={2016},
  publisher={Academic Press}
}

2015 (2)

A biophysical model for the staircase geometry of stereocilia. Orly, G., Manor, U., & Gov, N. S PloS one, 10(7): e0127926. 2015.
link bibtex

@article{orly2015biophysical,
  title={A biophysical model for the staircase geometry of stereocilia},
  author={Orly, Gilad and Manor, Uri and Gov, Nir S},
  journal={PloS one},
  volume={10},
  number={7},
  pages={e0127926},
  year={2015},
  publisher={Public Library of Science}
}

A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division. Manor, U., Bartholomew, S., Golani, G., Christenson, E., Kozlov, M., Higgs, H., Spudich, J., & Lippincott-Schwartz, J. elife, 4: e08828. 2015.
link bibtex 1 download

@article{manor2015mitochondria,
  title={A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division},
  author={Manor, Uri and Bartholomew, Sadie and Golani, Gonen and Christenson, Eric and Kozlov, Michael and Higgs, Henry and Spudich, James and Lippincott-Schwartz, Jennifer},
  journal={elife},
  volume={4},
  pages={e08828},
  year={2015},
  publisher={eLife Sciences Publications, Ltd}
}

2013 (3)

Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2. Furness, D. N, Johnson, S. L, Manor, U., Rüttiger, L., Tocchetti, A., Offenhauser, N., Olt, J., Goodyear, R. J, Vijayakumar, S., Dai, Y., & others Proceedings of the National Academy of Sciences, 110(34): 13898–13903. 2013.
link bibtex

@article{furness2013progressive,
  title={Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2},
  author={Furness, David N and Johnson, Stuart L and Manor, Uri and R{\"u}ttiger, Lukas and Tocchetti, Arianna and Offenhauser, Nina and Olt, Jennifer and Goodyear, Richard J and Vijayakumar, Sarath and Dai, Yuhai and others},
  journal={Proceedings of the National Academy of Sciences},
  volume={110},
  number={34},
  pages={13898--13903},
  year={2013},
  publisher={National Academy of Sciences}
}

Linking actin networks and cell membrane via a reaction-diffusion-elastic description of nonlinear filopodia initiation. Ben Isaac, E., Manor, U., Kachar, B., Yochelis, A., & Gov, N. S Physical Review E—Statistical, Nonlinear, and Soft Matter Physics, 88(2): 022718. 2013.
link bibtex

@article{ben2013linking,
  title={Linking actin networks and cell membrane via a reaction-diffusion-elastic description of nonlinear filopodia initiation},
  author={Ben Isaac, Eyal and Manor, Uri and Kachar, Bechara and Yochelis, Arik and Gov, Nir S},
  journal={Physical Review E—Statistical, Nonlinear, and Soft Matter Physics},
  volume={88},
  number={2},
  pages={022718},
  year={2013},
  publisher={American Physical Society}
}

Myosin 3A kinase activity is regulated by phosphorylation of the kinase domain activation loop. Quintero, O. A, Unrath, W. C, Stevens Jr, S. M, Manor, U., Kachar, B., & Yengo, C. M Journal of Biological Chemistry, 288(52): 37126–37137. 2013.
link bibtex

@article{quintero2013myosin,
  title={Myosin 3A kinase activity is regulated by phosphorylation of the kinase domain activation loop},
  author={Quintero, Omar A and Unrath, William C and Stevens Jr, Stanley M and Manor, Uri and Kachar, Bechara and Yengo, Christopher M},
  journal={Journal of Biological Chemistry},
  volume={288},
  number={52},
  pages={37126--37137},
  year={2013},
  publisher={Elsevier}
}

2012 (2)

Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions. Merritt, R. C, Manor, U., Salles, F. T, Grati, M., Dose, A. C, Unrath, W. C, Quintero, O. A, Yengo, C. M, & Kachar, B. Current biology, 22(4): 320–325. 2012.
link bibtex

@article{merritt2012myosin,
  title={Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions},
  author={Merritt, Raymond C and Manor, Uri and Salles, Felipe T and Grati, M'hamed and Dose, Andrea C and Unrath, William C and Quintero, Omar A and Yengo, Christopher M and Kachar, Bechara},
  journal={Current biology},
  volume={22},
  number={4},
  pages={320--325},
  year={2012},
  publisher={Elsevier}
}

Competition and compensation: dissecting the biophysical and functional differences between the class 3 myosin paralogs, myosins 3a and 3b. Manor, U., Grati, M., Yengo, C. M, Kachar, B., & Gov, N. S Bioarchitecture, 2(5): 171–174. 2012.
link bibtex

@article{manor2012competition,
  title={Competition and compensation: dissecting the biophysical and functional differences between the class 3 myosin paralogs, myosins 3a and 3b},
  author={Manor, Uri and Grati, M'hamed and Yengo, Christopher M and Kachar, Bechara and Gov, Nir S},
  journal={Bioarchitecture},
  volume={2},
  number={5},
  pages={171--174},
  year={2012},
  publisher={Taylor \& Francis}
}

2011 (2)

Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8. Manor, U., Disanza, A., Grati, M., Andrade, L., Lin, H., Di Fiore, P. P., Scita, G., & Kachar, B. Current Biology, 21(2): 167–172. 2011.
link bibtex

@article{manor2011regulation,
  title={Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8},
  author={Manor, Uri and Disanza, Andrea and Grati, M'Hamed and Andrade, Leonardo and Lin, Harrison and Di Fiore, Pier Paolo and Scita, Giorgio and Kachar, Bechara},
  journal={Current Biology},
  volume={21},
  number={2},
  pages={167--172},
  year={2011},
  publisher={Elsevier}
}

Dynamic regulation of stereocilia length by unconventional myosins and their actin-regulatory cargo. Manor, U. The Johns Hopkins University, 2011.
link bibtex

@book{manor2011dynamic,
  title={Dynamic regulation of stereocilia length by unconventional myosins and their actin-regulatory cargo},
  author={Manor, Uri},
  year={2011},
  publisher={The Johns Hopkins University}
}

2010 (1)

Intermolecular autophosphorylation regulates myosin IIIa activity and localization in parallel actin bundles. Quintero, O. A, Moore, J. E, Unrath, W. C, Manor, U., Salles, F. T, Grati, M., Kachar, B., & Yengo, C. M Journal of Biological Chemistry, 285(46): 35770–35782. 2010.
link bibtex

@article{quintero2010intermolecular,
  title={Intermolecular autophosphorylation regulates myosin IIIa activity and localization in parallel actin bundles},
  author={Quintero, Omar A and Moore, Judy E and Unrath, William C and Manor, Uri and Salles, Felipe T and Grati, M'hamed and Kachar, Bechara and Yengo, Christopher M},
  journal={Journal of Biological Chemistry},
  volume={285},
  number={46},
  pages={35770--35782},
  year={2010},
  publisher={Elsevier}
}

2009 (1)

Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments. Salles, F. T, Merritt Jr, R. C, Manor, U., Dougherty, G. W, Sousa, A. D, Moore, J. E, Yengo, C. M, Dosé, A. C, & Kachar, B. Nature cell biology, 11(4): 443–450. 2009.
link bibtex

@article{salles2009myosin,
  title={Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments},
  author={Salles, Felipe T and Merritt Jr, Raymond C and Manor, Uri and Dougherty, Gerard W and Sousa, Aurea D and Moore, Judy E and Yengo, Christopher M and Dos{\'e}, Andr{\'e}a C and Kachar, Bechara},
  journal={Nature cell biology},
  volume={11},
  number={4},
  pages={443--450},
  year={2009},
  publisher={Nature Publishing Group UK London}
}

2008 (3)

Dynamic length regulation of sensory stereocilia. Manor, U., & Kachar, B. In Seminars in cell & developmental biology, volume 19, pages 502–510, 2008. Academic Press
link bibtex

@inproceedings{manor2008dynamic,
  title={Dynamic length regulation of sensory stereocilia},
  author={Manor, Uri and Kachar, Bechara},
  booktitle={Seminars in cell \& developmental biology},
  volume={19},
  number={6},
  pages={502--510},
  year={2008},
  organization={Academic Press}
}

Protein localization by actin treadmilling and molecular motors regulates stereocilia shape and treadmilling rate. Naoz, M., Manor, U., Sakaguchi, H., Kachar, B., & Gov, N. S Biophysical journal, 95(12): 5706–5718. 2008.
link bibtex

@article{naoz2008protein,
  title={Protein localization by actin treadmilling and molecular motors regulates stereocilia shape and treadmilling rate},
  author={Naoz, Moshe and Manor, Uri and Sakaguchi, Hirofumi and Kachar, Bechara and Gov, Nir S},
  journal={Biophysical journal},
  volume={95},
  number={12},
  pages={5706--5718},
  year={2008},
  publisher={Elsevier}
}

Quantification of co-occurring reaction rates in deep subseafloor sediments. Wang, G., Spivack, A. J, Rutherford, S., Manor, U., & D’Hondt, S. Geochimica et Cosmochimica Acta, 72(14): 3479–3488. 2008.
link bibtex

@article{wang2008quantification,
  title={Quantification of co-occurring reaction rates in deep subseafloor sediments},
  author={Wang, Guizhi and Spivack, Arthur J and Rutherford, Scott and Manor, Uri and D’Hondt, Steven},
  journal={Geochimica et Cosmochimica Acta},
  volume={72},
  number={14},
  pages={3479--3488},
  year={2008},
  publisher={Elsevier}
}

undefined (2)

An Improved Numerical Model For Determining Chemical Reaction Rates. Manor, U., & Rutherford, S. SURFO Technical Report No. 2004-01,52. .
link bibtex

@article{manor2004improved,
  title={An Improved Numerical Model For Determining Chemical Reaction Rates},
  author={Manor, Uri and Rutherford, Scott},
  journal={SURFO Technical Report No. 2004-01},
  pages={52}
}

Machine Learning, Artificial Intelligence and Data Modeling for the Next Decade of Space Biology Research and Astronaut Health Support. Antonsen, E., Babdor, J., Baranzini, S. E, Barker, R., Beheshti, A., Berrios, D. C, Chalk, S., Delgado-Aparicio, G. M, Martin, H. G., Glicksberg, B. S, & others . .
link bibtex

@article{antonsenmachine,
  title={Machine Learning, Artificial Intelligence and Data Modeling for the Next Decade of Space Biology Research and Astronaut Health Support},
  author={Antonsen, Erik and Babdor, Joel and Baranzini, Sergio E and Barker, Richard and Beheshti, Afshin and Berrios, Daniel C and Chalk, Stuart and Delgado-Aparicio, Guillermo M and Martin, Hector Garcia and Glicksberg, Benjamin S and others}
}