@article{fukunaga_usefulness_2023,
	title = {Usefulness of {Voxel}-{Based} {Quantification} ({VBQ}) {Smoothing} in {Relaxation} {Time} {Mapping}},
	volume = {advpub},
	doi = {10.6009/jjrt.2023-1378},
	abstract = {Purpose: Voxel-based quantification (VBQ) smoothing is a technique used to smooth quantitative parametric maps in the Montreal Neurological Institute standard space. Although VBQ smoothing could suppress changes in quantitative values at tissue boundaries, its effectiveness on relaxation time (T1 and T2 values and proton density PD) maps has not been investigated. The purpose of this study was to clarify the usefulness of VBQ smoothing in relaxation time mapping.          Method: T1 and T2 values and PD maps of the brains of 20 healthy participants were obtained using a two-dimensional multi-dynamic multi-echo sequence. VBQ and Gaussian smoothing were applied to the relaxation time maps by varying the kernel size by 1 mm from 1 to 6 mm. Changes in relaxation time before and after VBQ and Gaussian smoothing for the putamen, caudate nucleus, substantia nigra, and corpus callosum on the relaxation time maps were evaluated.          Result: The changes in relaxation time after VBQ smoothing application were smaller than those in that after Gaussian smoothing application. Although the differences in the relaxation time for all tissues before and after VBQ and Gaussian smoothing applications increased with increasing kernel size for all relaxation times for both methods, the changes in the relaxation time for VBQ smoothing were smaller than those in that for Gaussian smoothing.          Conclusion: VBQ smoothing can suppress the change in the relaxation time on the boundary of the tissue and is thus a useful smoothing technique in relaxation time mapping.},
	journal = {Japanese Journal of Radiological Technology},
	author = {Fukunaga, Kota and Fujiwara, Yasuhiro and Enzaki, Masahiro and Komi, Masanori and Hirai, Toshinori and Azuma, Minako},
	year = {2023},
	keywords = {magnetic resonance imaging, quantitative MRI, relaxation time, smoothing, voxel-based analysis},
	pages = {2023--1378},
}

Paper  doi  abstract   bibtex   

@article{
 title = {Functional Outcome Prediction in Acute Ischemic Stroke Using a Fused Imaging and Clinical Deep Learning Model},
 type = {article},
 year = {2023},
 keywords = {goal,infarction,ischemic stroke,magnetic resonance imaging,quality of life},
 pages = {2316-2327},
 volume = {54},
 id = {80c16dd4-2652-3cc5-923d-0ddb7eb0bb21},
 created = {2024-01-13T07:02:56.805Z},
 file_attached = {true},
 profile_id = {d5b9f595-4104-33d2-b640-e84dee1b7ded},
 last_modified = {2025-02-21T12:00:48.744Z},
 read = {false},
 starred = {false},
 authored = {true},
 confirmed = {true},
 hidden = {false},
 folder_uuids = {ded4b384-1a9c-491d-88dd-c5e6a88d479d},
 private_publication = {false},
 abstract = {BACKGROUND: Predicting long-term clinical outcome based on the early acute ischemic stroke information is valuable for prognostication, resource management, clinical trials, and patient expectations. Current methods require subjective decisions about which imaging features to assess and may require time-consuming postprocessing. This study's goal was to predict ordinal 90-day modified Rankin Scale (mRS) score in acute ischemic stroke patients by fusing a Deep Learning model of diffusion-weighted imaging images and clinical information from the acute period. METHODS: A total of 640 acute ischemic stroke patients who underwent magnetic resonance imaging within 1 to 7 days poststroke and had 90-day mRS follow-up data were randomly divided into 70% (n=448) for model training, 15% (n=96) for validation, and 15% (n=96) for internal testing. Additionally, external testing on a cohort from Lausanne University Hospital (n=280) was performed to further evaluate model generalization. Accuracy for ordinal mRS, accuracy within ±1 mRS category, mean absolute prediction error, and determination of unfavorable outcome (mRS score >2) were evaluated for clinical only, imaging only, and 2 fused clinical-imaging models. RESULTS: The fused models demonstrated superior performance in predicting ordinal mRS score and unfavorable outcome in both internal and external test cohorts when compared with the clinical and imaging models. For the internal test cohort, the top fused model had the highest area under the curve of 0.92 for unfavorable outcome prediction and the lowest mean absolute error (0.96 [95% CI, 0.77-1.16]), with the highest proportion of mRS score predictions within ±1 category (79% [95% CI, 71%-88%]). On the external Lausanne University Hospital cohort, the best fused model had an area under the curve of 0.90 for unfavorable outcome prediction and outperformed other models with an mean absolute error of 0.90 (95% CI, 0.79-1.01), and the highest percentage of mRS score predictions within ±1 category (83% [95% CI, 78%-87%]). CONCLUSIONS: A Deep Learning-based imaging model fused with clinical variables can be used to predict 90-day stroke outcome with reduced subjectivity and user burden.},
 bibtype = {article},
 author = {Liu, Yongkai and Yu, Yannan and Ouyang, Jiahong and Jiang, Bin and Yang, Guang and Ostmeier, Sophie and Wintermark, Max and Michel, Patrik and Liebeskind, David S. and Lansberg, Maarten G. and Albers, Gregory W. and Zaharchuk, Greg},
 doi = {10.1161/STROKEAHA.123.044072},
 journal = {Stroke},
 number = {9}
}

@article{oomer_resting-state_2022,
	title = {Resting-state network connectivity in cannabis-induced psychosis: {Is} it different from first episode schizophrenia with heavy cannabis use?},
	volume = {75},
	issn = {1876-2026 1876-2018},
	doi = {10.1016/j.ajp.2022.103201},
	language = {eng},
	journal = {Asian journal of psychiatry},
	author = {Oomer, Fareed and Ghosh, Abhishek and Ahuja, Chirag K. and Basu, Debasish and Holla, Bharath and Avasthi, Ajit},
	month = sep,
	year = {2022},
	pmid = {35841847},
	note = {Place: Netherlands},
	keywords = {*Cannabis/adverse effects, *Hallucinogens, *Marijuana Abuse/complications, *Psychotic Disorders, *Schizophrenia, Cannabis, Humans, Magnetic Resonance Imaging, Psychosis, Resting State Connectivity},
	pages = {103201},
}

@article{yi_spatial_2022,
	title = {Spatial {Relation} {Between} {White} {Matter} {Hyperintensities} and {Incident} {Lacunes} of {Presumed} {Vascular} {Origin}: {A} 14-{Year} {Follow}-{Up} {Study}},
	volume = {53},
	issn = {1524-4628},
	shorttitle = {Spatial {Relation} {Between} {White} {Matter} {Hyperintensities} and {Incident} {Lacunes} of {Presumed} {Vascular} {Origin}},
	doi = {10.1161/STROKEAHA.122.039903},
	abstract = {BACKGROUND: The underlying mechanisms of incident lacunes regarding their spatial distribution remain largely unknown. We investigated the spatial distribution pattern and MRI predictors of incident lacunes in relation to white matter hyperintensity (WMH) over 14 years follow-up in sporadic small vessel disease.
METHODS: Five hundred three participants from the ongoing prospective single-center Radboud University Nijmegen Diffusion Tensor and Magnetic resonance Cohort (RUN DMC) were recruited with baseline assessment in 2006 and follow ups in 2011, 2015, and 2020. Three hundred eighty-two participants who underwent at least 2 available brain MRI scans were included. Incident lacunes were systematically identified, and the spatial relationship between incident lacunes located in subcortical white matter and WMH were determined using a visual rating scale. Adjusted multiple logistic regression and linear mixed-effect regression models were used to assess the association between baseline small vessel disease markers, WMH progression, and incident lacunes. Participants with atrial fibrillation were excluded in multivariable analysis.
RESULTS: Eighty incident lacunes were identified in 43 patients (mean age 66.5±8.2 years, 37.2\% women) during a mean follow-up time of 11.2±3.3 years (incidence rate 10.0/1000 person-year). Sixty percent of incident lacunes were in the white matter, of which 48.9\% showed no contact with preexisting WMH. Baseline WMH volume (odds ratio=2.5 [95\% CI, 1.6-4.2]) predicted incident lacunes after adjustment for age, sex, and vascular risk factors. WMH progression was associated with incident lacunes independent of age, sex, baseline WMH volume, and vascular risk factors (odds ratio, 3.2 [95\% CI, 1.5-6.9]). Baseline WMH volume and progression rate were higher in participants with incident lacunes in contact with preexisting WMH. No difference in vascular risk factors was observed regarding location or relation with preexisting WMH.
CONCLUSIONS: The 2 different distribution patterns of lacunes regarding their relation to WMH may suggest distinct underlying mechanisms, one of which may be more closely linked to a similar pathophysiology as that of WMH. The longitudinal relation between WMH and lacunes further supports plausible shared mechanisms between the 2 key markers.},
	language = {eng},
	number = {12},
	journal = {Stroke},
	author = {Yi, Fang and Cai, Mengfei and Jacob, Mina A. and Marques, José and Norris, David G. and Duering, Marco and Tuladhar, Anil M. and de Leeuw, Frank-Erik},
	month = dec,
	year = {2022},
	pmid = {36189679},
	pmcid = {PMC9698104},
	keywords = {small vessel disease, Aged, Female, Humans, Male, Middle Aged, Prospective Studies, Follow-Up Studies, Magnetic Resonance Imaging, white matter hyperintensities, magnetic resonance imaging, White Matter, Cerebral Small Vessel Diseases, Leukoaraiosis, incident lacunes, spatial distribution},
	pages = {3688--3695},
	file = {Full Text:/Users/mduering/Zotero/storage/E6C97ZU8/Yi et al. - 2022 - Spatial Relation Between White Matter Hyperintensi.pdf:application/pdf},
}

@article{de_brito_robalo_diffusion_2021,
	title = {Diffusion {MRI} harmonization enables joint-analysis of multicentre data of patients with cerebral small vessel disease},
	volume = {32},
	issn = {2213-1582},
	doi = {10.1016/j.nicl.2021.102886},
	abstract = {OBJECTIVES: Acquisition-related differences in diffusion magnetic resonance imaging (dMRI) hamper pooling of multicentre data to achieve large sample sizes. A promising solution is to harmonize the raw diffusion signal using rotation invariant spherical harmonic (RISH) features, but this has not been tested in elderly subjects. Here we aimed to establish if RISH harmonization effectively removes acquisition-related differences in multicentre dMRI of elderly subjects with cerebral small vessel disease (SVD), while preserving sensitivity to disease effects.
METHODS: Five cohorts of patients with SVD (N = 397) and elderly controls (N = 175) with 3 Tesla MRI on different systems were included. First, to establish effectiveness of harmonization, the RISH method was trained with data of 13 to 15 age and sex-matched controls from each site. Fractional anisotropy (FA) and mean diffusivity (MD) were compared in matched controls between sites using tract-based spatial statistics (TBSS) and voxel-wise analysis, before and after harmonization. Second, to assess sensitivity to disease effects, we examined whether the contrast (effect sizes of FA, MD and peak width of skeletonized MD - PSMD) between patients and controls within each site remained unaffected by harmonization. Finally, we evaluated the association between white matter hyperintensity (WMH) burden, FA, MD and PSMD using linear regression analyses both within individual cohorts as well as with pooled scans from multiple sites, before and after harmonization.
RESULTS: Before harmonization, significant differences in FA and MD were observed between matched controls of different sites (p {\textless} 0.05). After harmonization these site-differences were removed. Within each site, RISH harmonization did not alter the effect sizes of FA, MD and PSMD between patients and controls (relative change in Cohen's d = 4 \%) nor the strength of association with WMH volume (relative change in R2 = 2.8 \%). After harmonization, patient data of all sites could be aggregated in a single analysis to infer the association between WMH volume and FA (R2 = 0.62), MD (R2 = 0.64), and PSMD (R2 = 0.60).
CONCLUSIONS: We showed that RISH harmonization effectively removes acquisition-related differences in dMRI of elderly subjects while preserving sensitivity to SVD-related effects. This study provides proof of concept for future multicentre SVD studies with pooled datasets.},
	language = {eng},
	journal = {Neuroimage Clin},
	author = {de Brito Robalo, Bruno M. and Biessels, Geert Jan and Chen, Christopher and Dewenter, Anna and Duering, Marco and Hilal, Saima and Koek, Huiberdina L. and Kopczak, Anna and Yin Ka Lam, Bonnie and Leemans, Alexander and Mok, Vincent and Onkenhout, Laurien P. and van den Brink, Hilde and de Luca, Alberto},
	year = {2021},
	pmid = {34911192},
	pmcid = {PMC8609094},
	keywords = {Aged, Diffusion Magnetic Resonance Imaging, Humans, Magnetic Resonance Imaging, Regression Analysis, White matter hyperintensities, Anisotropy, White Matter, Cerebral Small Vessel Diseases, Cerebral small vessel disease, Diffusion MRI, Harmonization, Multicentre},
	pages = {102886},
	file = {Full Text:/Users/mduering/Zotero/storage/ECPI9WYI/de Brito Robalo et al. - 2021 - Diffusion MRI harmonization enables joint-analysis.pdf:application/pdf},
}

Paper  doi  bibtex   

@article{dessouky_comparison_2021,
	title = {Comparison of free breathing {3D} {mDIXON} with single breath-hold {3D} inversion recovery sequences for the assessment of {Late} {Gadolinium} {Enhancement}},
	volume = {134},
	issn = {0720-048X, 1872-7727},
	url = {https://www.ejradiology.com/article/S0720-048X(20)30617-3/fulltext},
	doi = {10.1016/j.ejrad.2020.109427},
	language = {English},
	urldate = {2021-11-11},
	journal = {European Journal of Radiology},
	author = {Dessouky, Riham and Stasio, Vincenzo De and Boccalini, Sara and Si-Mohamed, Salim and Broussaud, Thomas and Douek, Philippe and Sigovan, Monica},
	month = jan,
	year = {2021},
	pmid = {33307461},
	note = {Publisher: Elsevier},
	keywords = {2D, 3D, CMR, CNR, Cardiac magnetic resonance imaging, DIXON based fat-supression, FOV, IR, LGE, Magnetic resonance imaging, SENSE, SENSitivity Encoding, SNR, SPIR, SSFP, Three-dimensional Image, VIAB, contrast-to-noise ratio, field of view, inversion recovery, inversion recovery fast recalled gradient echo sequence, late gadolinium enhancement, mDIXON, modified DIXON sequence, signal-to-noise ratio, spectral presaturation with inversion recovery sequence, steady state free precision, three dimensional, two dimensional},
}

@article{feng_brief_2021,
	title = {Brief postnatal visual deprivation triggers long-lasting interactive structural and functional reorganization of the human cortex},
	volume = {8},
	issn = {2296858X},
	doi = {10.3389/fmed.2021.752021},
	abstract = {Patients treated for bilateral congenital cataracts provide a unique model to test the role of early visual input in shaping the development of the human cortex. Previous studies showed that brief early visual deprivation triggers long-lasting changes in the human visual cortex. However, it remains unknown if such changes interact with the development of other parts of the cortex. With high-resolution structural and resting-state fMRI images, we found changes in cortical thickness within, but not limited to, the visual cortex in adult patients, who experienced transient visual deprivation early in life as a result of congenital cataracts. Importantly, the covariation of cortical thickness across regions was also altered in the patients. The areas with altered cortical thickness in patients also showed differences in functional connectivity between patients and normally sighted controls. Together, the current findings suggest an impact of early visual deprivation on the interactive development of the human cortex.},
	number = {November},
	journal = {Frontiers in Medicine},
	author = {Feng, Yixuan and Collignon, Olivier and Maurer, Daphne and Yao, Ke and Gao, Xiaoqing},
	year = {2021},
	keywords = {congenital cataracts, cortical thickness covariation, early visual deprivation, functional connectivity, magnetic resonance imaging},
	pages = {1--9},
}

Paper  doi  abstract   bibtex   

@article{esteban_analysis_2020,
	title = {Analysis of task-based functional {MRI} data preprocessed with {fMRIPrep}},
	volume = {15},
	copyright = {2020 The Author(s), under exclusive licence to Springer Nature Limited},
	issn = {1750-2799},
	url = {https://www.nature.com/articles/s41596-020-0327-3},
	doi = {10.1038/s41596-020-0327-3},
	abstract = {Functional magnetic resonance imaging (fMRI) is a standard tool to investigate the neural correlates of cognition. fMRI noninvasively measures brain activity, allowing identification of patterns evoked by tasks performed during scanning. Despite the long history of this technique, the idiosyncrasies of each dataset have led to the use of ad-hoc preprocessing protocols customized for nearly every different study. This approach is time consuming, error prone and unsuitable for combining datasets from many sources. Here we showcase fMRIPrep (http://fmriprep.org), a robust tool to prepare human fMRI data for statistical analysis. This software instrument addresses the reproducibility concerns of the established protocols for fMRI preprocessing. By leveraging the Brain Imaging Data Structure to standardize both the input datasets (MRI data as stored by the scanner) and the outputs (data ready for modeling and analysis), fMRIPrep is capable of preprocessing a diversity of datasets without manual intervention. In support of the growing popularity of fMRIPrep, this protocol describes how to integrate the tool in a task-based fMRI investigation workflow.},
	language = {en},
	number = {7},
	urldate = {2023-03-11},
	journal = {Nature Protocols},
	author = {Esteban, Oscar and Ciric, Rastko and Finc, Karolina and Blair, Ross W. and Markiewicz, Christopher J. and Moodie, Craig A. and Kent, James D. and Goncalves, Mathias and DuPre, Elizabeth and Gomez, Daniel E. P. and Ye, Zhifang and Salo, Taylor and Valabregue, Romain and Amlien, Inge K. and Liem, Franziskus and Jacoby, Nir and Stojić, Hrvoje and Cieslak, Matthew and Urchs, Sebastian and Halchenko, Yaroslav O. and Ghosh, Satrajit S. and De La Vega, Alejandro and Yarkoni, Tal and Wright, Jessey and Thompson, William H. and Poldrack, Russell A. and Gorgolewski, Krzysztof J.},
	month = jul,
	year = {2020},
	note = {Number: 7
Publisher: Nature Publishing Group},
	keywords = {Computational neuroscience, Magnetic resonance imaging, Neurological models, Software},
	pages = {2186--2202},
	file = {Accepted Version:/home/tchaase/snap/zotero-snap/common/Zotero/storage/NHJAVWLK/Esteban et al. - 2020 - Analysis of task-based functional MRI data preproc.pdf:application/pdf},
}

@article{correia_accelerated_2020,
	title = {Accelerated high-resolution free-breathing {3D} whole-heart {T2}-prepared black-blood and bright-blood cardiovascular magnetic resonance},
	volume = {22},
	issn = {1532-429X},
	doi = {10.1186/s12968-020-00691-3},
	abstract = {BACKGROUND: The free-breathing 3D whole-heart T2-prepared Bright-blood and black-blOOd phase SensiTive inversion recovery (BOOST) cardiovascular magnetic resonance (CMR) sequence was recently proposed for simultaneous bright-blood coronary CMR angiography and black-blood late gadolinium enhancement (LGE) imaging. This sequence enables simultaneous visualization of cardiac anatomy, coronary arteries and fibrosis. However, high-resolution ({\textless} 1.4 × 1.4 × 1.4 mm3) fully-sampled BOOST requires long acquisition times of {\textasciitilde} 20 min.
METHODS: In this work, we propose to extend a highly efficient respiratory-resolved motion-corrected reconstruction framework (XD-ORCCA) to T2-prepared BOOST to enable high-resolution 3D whole-heart coronary CMR angiography and black-blood LGE in a clinically feasible scan time. Twelve healthy subjects were imaged without contrast injection (pre-contrast BOOST) and 10 patients with suspected cardiovascular disease were imaged after contrast injection (post-contrast BOOST). A quantitative analysis software was used to compare accelerated pre-contrast BOOST against the fully-sampled counterpart (vessel sharpness and length of the left and right coronary arteries). Moreover, three cardiologists performed diagnostic image quality scoring for clinical 2D LGE and both bright- and black-blood 3D BOOST imaging using a 4-point scale (1-4, non-diagnostic-fully diagnostic). A two one-sided test of equivalence (TOST) was performed to compare the pre-contrast BOOST images. Nonparametric TOST was performed to compare post-contrast BOOST image quality scores.
RESULTS: The proposed method produces images from 3.8 × accelerated non-contrast-enhanced BOOST acquisitions with comparable vessel length and sharpness to those obtained from fully- sampled scans in healthy subjects. Moreover, in terms of visual grading, the 3D BOOST LGE datasets (median 4) and the clinical 2D counterpart (median 3.5) were found to be statistically equivalent (p {\textless} 0.05). In addition, bright-blood BOOST images allowed for visualization of the proximal and middle left anterior descending and right coronary sections with high diagnostic quality (mean score {\textgreater} 3.5).
CONCLUSIONS: The proposed framework provides high-resolution 3D whole-heart BOOST images from a single free-breathing acquisition in {\textasciitilde} 7 min.},
	language = {eng},
	number = {1},
	journal = {Journal of Cardiovascular Magnetic Resonance: Official Journal of the Society for Cardiovascular Magnetic Resonance},
	author = {Correia, Teresa and Ginami, Giulia and Rashid, Imran and Nordio, Giovanna and Hajhosseiny, Reza and Ismail, Tevfik F. and Neji, Radhouene and Botnar, René M. and Prieto, Claudia},
	month = dec,
	year = {2020},
	pmid = {33317570},
	pmcid = {PMC7737390},
	keywords = {Adult, Aged, Aged, 80 and over, Black-blood, Case-Control Studies, Compressed sensing, Contrast Media, Coronary Vessels, Coronary magnetic resonance angiography (CMRA), Female, Fibrosis, Heart Diseases, Humans, Image navigator, Imaging, Three-Dimensional, Late gadolinium enhancement (LGE), Magnetic Resonance Imaging, Male, Middle Aged, Myocardium, Predictive Value of Tests, Reproducibility of Results, Respiratory motion compensation, Workflow, Young Adult},
	pages = {88},
}

Website  abstract   bibtex   

@article{
 title = {Intrinsic functional and structural connectivity of emotion regulation networks in obsessive-compulsive disorder},
 type = {article},
 year = {2019},
 identifiers = {[object Object]},
 keywords = {Adult,Amygdala,Case-Control Studies,Emotions,Female,Humans,Magnetic Resonance Imaging,Male,Obsessive-Compulsive Disorder},
 pages = {110-120},
 volume = {36},
 websites = {http://www.ncbi.nlm.nih.gov/pubmed/30253000},
 id = {da7dfdeb-3ba9-322b-bbdc-f9d9b860019d},
 created = {2020-09-17T09:27:48.121Z},
 file_attached = {false},
 profile_id = {20f87055-ac78-3c65-9cf5-216a3558d16a},
 group_id = {14ca8526-77d5-34fd-89de-e48cae5e6ee2},
 last_modified = {2020-09-17T09:27:48.121Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 source_type = {JOUR},
 language = {eng},
 private_publication = {false},
 abstract = {Despite emotion regulation being altered in patients with obsessive-compulsive disorder (OCD), no studies have investigated its relation to multimodal amygdala connectivity. We compared corticolimbic functional and structural connectivity between OCD patients and healthy controls (HCs), and correlated this with the dispositional use of emotion regulation strategies and with OCD severity. OCD patients (n = 73) and HCs (n = 42) were assessed for suppression and reappraisal strategies using the Emotion Regulation Questionnaire (ERQ) and for OCD severity using the Yale-Brown Obsessive-Compulsive Scale. Resting-state functional magnetic resonance imaging (rs-fMRI) connectivity maps were generated using subject-specific left amygdala (LA) and right amygdala (RA) masks. We identified between-group differences in amygdala whole-brain connectivity, and evaluated the moderating effect of ERQ strategies. Significant regions and amygdala seeds were used as targets in probabilistic tractography analysis. Patients scored higher in suppression and lower in reappraisal. We observed higher rs-fMRI RA-right postcentral gyrus (PCG) connectivity in HC, and in patients this was correlated with symptom severity. Reappraisal scores were associated with higher negative LA-left insula connectivity in HC, and suppression scores were negatively associated with LA-precuneus and angular gyri connectivity in OCD. Structurally, patients showed higher mean diffusivity in tracts connecting the amygdala with the other targets. RA-PCG connectivity is diminished in patients, while disrupted emotion regulation is related to altered amygdala connectivity with the insula and posterior brain regions. Our results are the first showing, from a multimodal perspective, the association between amygdala connectivity and specific emotional processing domains, emphasizing the importance of amygdala connectivity in OCD pathophysiology.},
 bibtype = {article},
 author = {Picó-Pérez, Maria and Ipser, Jonathan and Taylor, Paul and Alonso, Pino and López-Solà, Clara and Real, Eva and Segalàs, Cinto and Roos, Annerine and Menchón, José M and Stein, Dan J and Soriano-Mas, Carles},
 journal = {Depression and Anxiety},
 number = {2}
}

Website  doi  abstract   bibtex   

@article{
 title = {Automatic Age Estimation and Majority Age Classification From Multi-Factorial MRI Data},
 type = {article},
 year = {2019},
 keywords = {Information fusion,age estimation,convolutional neural network,magnetic resonance imaging,majority age classification,multi-factorial},
 pages = {1392-1403},
 volume = {23},
 websites = {https://ieeexplore.ieee.org/document/8470073/},
 month = {7},
 id = {49adad65-c47c-3592-9d87-d116f916e434},
 created = {2018-09-29T17:57:07.819Z},
 file_attached = {false},
 profile_id = {53d1e3c7-2f16-3c81-9a84-dccd45be4841},
 last_modified = {2020-01-23T23:19:31.299Z},
 read = {false},
 starred = {false},
 authored = {true},
 confirmed = {true},
 hidden = {false},
 citation_key = {Stern2019JBHI},
 folder_uuids = {0ec41d70-75f1-4a99-820b-0a83ccc37f54},
 private_publication = {false},
 abstract = {Age estimation from radiologic data is an important topic both in clinical medicine as well as in forensic applications, where it is used to assess unknown chronological age or to discriminate minors from adults. In this paper, we propose an automatic multi-factorial age estimation method based on MRI data of hand, clavicle, and teeth to extend the maximal age range from up to 19 years, as commonly used for age assessment based on hand bones, to up to 25 years, when combined with clavicle bones and wisdom teeth. Fusing age-relevant information from all three anatomical sites, our method utilizes a deep convolutional neural network that is trained on a dataset of 322 subjects in the age range between 13 and 25 years, to achieve a mean absolute prediction error in regressing chronological age of 1.01± 0.74 years. Furthermore, when used for majority age classification, we show that a classifier derived from thresholding our regression-based predictor is better suited than a classifier directly trained with a classification loss, especially when taking into account that those cases of minors being wrongly classified as adults need to be minimized. In conclusion, we overcome the limitations of the multi-factorial methods currently used in forensic practice, i.e., dependence on ionizing radiation, subjectivity in quantifying age-relevant information, and lack of an established approach to fuse this information from individual anatomical sites.},
 bibtype = {article},
 author = {Stern, Darko and Payer, Christian and Giuliani, Nicola and Urschler, Martin},
 doi = {10.1109/JBHI.2018.2869606},
 journal = {IEEE Journal of Biomedical and Health Informatics},
 number = {4}
}

@article{franzmeier_left_2018-1,
	title = {Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic {Alzheimer}'s disease},
	volume = {141},
	issn = {1460-2156 (Electronic) 0006-8950 (Linking)},
	doi = {10.1093/brain/awy008},
	abstract = {Patients with Alzheimer's disease vary in their ability to sustain cognitive abilities in the presence of brain pathology. A major open question is which brain mechanisms may support higher reserve capacity, i.e. relatively high cognitive performance at a given level of Alzheimer's pathology. Higher functional MRI-assessed functional connectivity of a hub in the left frontal cortex is a core candidate brain mechanism underlying reserve as it is associated with education (i.e. a protective factor often associated with higher reserve) and attenuated cognitive impairment in prodromal Alzheimer's disease. However, no study has yet assessed whether such hub connectivity of the left frontal cortex supports reserve throughout the evolution of pathological brain changes in Alzheimer's disease, including the presymptomatic stage when cognitive decline is subtle. To address this research gap, we obtained cross-sectional resting state functional MRI in 74 participants with autosomal dominant Alzheimer's disease, 55 controls from the Dominantly Inherited Alzheimer's Network and 75 amyloid-positive elderly participants, as well as 41 amyloid-negative cognitively normal elderly subjects from the German Center of Neurodegenerative Diseases multicentre study on biomarkers in sporadic Alzheimer's disease. For each participant, global left frontal cortex connectivity was computed as the average resting state functional connectivity between the left frontal cortex (seed) and each voxel in the grey matter. As a marker of disease stage, we applied estimated years from symptom onset in autosomal dominantly inherited Alzheimer's disease and cerebrospinal fluid tau levels in sporadic Alzheimer's disease cases. In both autosomal dominant and sporadic Alzheimer's disease patients, higher levels of left frontal cortex connectivity were correlated with greater education. For autosomal dominant Alzheimer's disease, a significant left frontal cortex connectivity x estimated years of onset interaction was found, indicating slower decline of memory and global cognition at higher levels of connectivity. Similarly, in sporadic amyloid-positive elderly subjects, the effect of tau on cognition was attenuated at higher levels of left frontal cortex connectivity. Polynomial regression analysis showed that the trajectory of cognitive decline was shifted towards a later stage of Alzheimer's disease in patients with higher levels of left frontal cortex connectivity. Together, our findings suggest that higher resilience against the development of cognitive impairment throughout the early stages of Alzheimer's disease is at least partially attributable to higher left frontal cortex-hub connectivity.},
	number = {4},
	journal = {Brain},
	author = {Franzmeier, N. and Duzel, E. and Jessen, F. and Buerger, K. and Levin, J. and Duering, M. and Dichgans, M. and Haass, C. and Suarez-Calvet, M. and Fagan, A. M. and Paumier, K. and Benzinger, T. and Masters, C. L. and Morris, J. C. and Perneczky, R. and Janowitz, D. and Catak, C. and Wolfsgruber, S. and Wagner, M. and Teipel, S. and Kilimann, I. and Ramirez, A. and Rossor, M. and Jucker, M. and Chhatwal, J. and Spottke, A. and Boecker, H. and Brosseron, F. and Falkai, P. and Fliessbach, K. and Heneka, M. T. and Laske, C. and Nestor, P. and Peters, O. and Fuentes, M. and Menne, F. and Priller, J. and Spruth, E. J. and Franke, C. and Schneider, A. and Kofler, B. and Westerteicher, C. and Speck, O. and Wiltfang, J. and Bartels, C. and Araque Caballero, M. A. and Metzger, C. and Bittner, D. and Weiner, M. and Lee, J. H. and Salloway, S. and Danek, A. and Goate, A. and Schofield, P. R. and Bateman, R. J. and Ewers, M.},
	month = apr,
	year = {2018},
	pmcid = {PMC5888938},
	pmid = {29462334},
	keywords = {Adult, Female, Humans, Male, Middle Aged, Magnetic Resonance Imaging, Presenilin-1, Mutation, Brain Mapping, Functional Laterality, Frontal Lobe/*diagnostic imaging, Functional Laterality/*physiology, Alzheimer Disease/*complications/diagnostic imaging/genetics, Amyloid beta-Protein Precursor/genetics, Cognitive Dysfunction/*diagnostic imaging/*etiology, Imaging, Three-Dimensional, Mutation/genetics, Nerve Net/*diagnostic imaging/physiology, Presenilin-1/genetics, Presenilin-2/genetics, Presenilin-2, Alzheimer Disease, Frontal Lobe, Amyloid beta-Protein Precursor, Cognitive Dysfunction, Nerve Net},
	pages = {1186--1200},
}

@article {650286,
	title = {Gadolinium Retention After Contrast-Enhanced MRI},
	journal = {JAMA},
	volume = {320},
	number = {18},
	year = {2018},
	month = {2018 Nov 13},
	pages = {1853-1854},
	keywords = {Contrast Media, Drug Labeling, Gadolinium, Humans, Magnetic Resonance Imaging, Nephrogenic Fibrosing Dermopathy, United States, United States Food and Drug Administration},
	issn = {1538-3598},
	doi = {10.1001/jama.2018.13362},
	author = {Levine, Deborah and McDonald, Robert J and Kressel, Herbert Y}
}

@article{lee_deep_2017,
	title = {Deep {Learning} in {Medical} {Imaging}: {General} {Overview}.},
	volume = {18},
	issn = {2005-8330 1229-6929},
	doi = {10.3348/kjr.2017.18.4.570},
	abstract = {The artificial neural network (ANN)-a machine learning technique inspired by the human neuronal synapse system-was introduced in the 1950s. However, the ANN was  previously limited in its ability to solve actual problems, due to the vanishing  gradient and overfitting problems with training of deep architecture, lack of  computing power, and primarily the absence of sufficient data to train the  computer system. Interest in this concept has lately resurfaced, due to the  availability of big data, enhanced computing power with the current graphics  processing units, and novel algorithms to train the deep neural network. Recent  studies on this technology suggest its potentially to perform better than humans  in some visual and auditory recognition tasks, which may portend its applications  in medicine and healthcare, especially in medical imaging, in the foreseeable  future. This review article offers perspectives on the history, development, and  applications of deep learning technology, particularly regarding its applications  in medical imaging.},
	language = {eng},
	number = {4},
	journal = {Korean journal of radiology},
	author = {Lee, June-Goo and Jun, Sanghoon and Cho, Young-Won and Lee, Hyunna and Kim, Guk Bae and Seo, Joon Beom and Kim, Namkug},
	month = aug,
	year = {2017},
	pmid = {28670152},
	pmcid = {PMC5447633},
	note = {Place: Korea (South)},
	keywords = {*Algorithms, *Neural Networks, Computer, Artificial intelligence, Computer-aided, Convolutional neural network, Humans, Image Processing, Computer-Assisted, Knee/diagnostic imaging, Machine learning, Magnetic Resonance Imaging, Optical Imaging/methods, Precision medicine, Radiology, Recurrent Neural Network},
	pages = {570--584},
}

@article{de_reuck_frequency_2017,
	title = {Frequency and topography of small cerebrovascular lesions in vascular and in mixed dementia: a post-mortem 7-tesla magnetic resonance imaging study with neuropathological correlates},
	volume = {55},
	issn = {1509-572X},
	shorttitle = {Frequency and topography of small cerebrovascular lesions in vascular and in mixed dementia},
	doi = {10.5114/fn.2017.66711},
	abstract = {\textit{\textbf{Introduction}: Mixed dementia (MixD) refers to a combination of definite Alzheimer's disease (AD) and vascular encephalopathy. The existence of a "pure" type of vascular dementia (VaD) is controversial. There is a need to find magnetic resonance imaging (MRI) characteristics allowing the distinction between VaD and MixD. The present post-mortem 7.0-tesla MRI compares the frequency or severity and the topography of the small cerebrovascular lesions in brains of patients with VaD and with MixD. \textbf{Material and methods}: Based on neuropathological criteria, 14 brains were classified as VaD, 24 as MixD and 11 as controls. Three coronal sections of a cerebral hemisphere and a horizontal section of a cerebellar hemisphere underwent T2 and T2* 7.0-tesla MRI examination. The mean values and topographic distribution of white matter changes (WMCs), lacunar infarcts (LIs), cortical microbleeds (CoMBs) and cortical microinfarcts (CoMIs) were determined and compared between the different groups. \textbf{Results}: Compared to the controls, both VaD and MixD brains had significantly more severe WMCs and increased numbers of CoMBs and CoMIs. Lacunar infarcts predominated only in the VaD cases. On mutual comparison of VaD and MixD brains, CoMBs and CoMIs predominated in the frontal lobe and the cerebellum of VaD, while were mainly present in the occipital lobe of MixD. White matter changes predominated in the temporal lobe of MixD cases. Lacunar infarcts were significantly increased in the corona radiata and putamen of VaD patients. \textbf{Conclusions}: The present post-mortem MRI study shows clear differences in the distribution and the types of cerebrovascular lesions on high-field MRI, confirming that VaD and MixD are different diseases. }.},
	language = {eng},
	number = {1},
	journal = {Folia Neuropathologica},
	author = {De Reuck, Jacques and Auger, Florent and Durieux, Nicolas and Deramecourt, Vincent and Maurage, Claude-Alain and Cordonnier, Charlotte and Pasquier, Florence and Leys, Didier and Bordet, Regis},
	year = {2017},
	pmid = {28430290},
	keywords = {Aged, Humans, Magnetic Resonance Imaging, Dementia, Female, Male, Brain, Autopsy, vascular dementia, cortical microbleeds, cortical microinfarcts, lacunar infarcts, mixed dementia, post-mortem 7.0-tesla MRI, topographic distribution of small cerebrovascular lesions, white matter changes},
	pages = {31--37}
}

Paper  bibtex   

@article{lin_yoga_2017,
	title = {Yoga reduces the brain's amplitude of low-frequency fluctuations in patients with early psychosis results of a randomized controlled trial},
	volume = {184},
	issn = {1573-2509},
	url = {https://www.ncbi.nlm.nih.gov/pubmed/27913158},
	language = {eng},
	urldate = {0006-01-01},
	journal = {Schizophrenia research},
	author = {Lin, Jingxia and Geng, Xiujuan and Lee, Edwin Hm and Chan, Sherry Kw and Chang, Wing Chung and Hui, Christy Lm and Tse, Michael and Chan, Cecilia Lw and Khong, P L and Honer, William G and Chen, Eric Yh},
	year = {2017},
	keywords = {*Yoga, Antipsychotic Agents/therapeutic use, Brain, Exercise, Female, Follow-Up Studies, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Oxygen/blood, Psychiatric Status Rating Scales, Psychotic Disorders, Schizophrenia/*diagnostic imaging/*rehabilitation, Visual Cortex/*diagnostic imaging/*physiopathology},
	pages = {141--142},
}

Website  abstract   bibtex   

@article{
 title = {Assessing the psychedelic "after-glow" in ayahuasca users: Post-acute neurometabolic and functional connectivity changes are associated with enhanced mindfulness capacities},
 type = {article},
 year = {2017},
 identifiers = {[object Object]},
 keywords = {Ayahuasca,Human,Magnetic resonance Imaging,Mindfulness,Psychedelic After-effects},
 pages = {698-711},
 volume = {20},
 websites = {https://academic.oup.com/ijnp/article-lookup/doi/10.1093/ijnp/pyx036},
 id = {3f5e337e-0d03-39b1-830b-5aade057fc25},
 created = {2017-11-10T18:19:09.331Z},
 file_attached = {false},
 profile_id = {38c6dbcb-2394-3f18-9217-58d777c08c69},
 group_id = {d9389c6c-8ab5-3b8b-86ed-33db09ca0198},
 last_modified = {2019-10-23T13:46:49.607Z},
 tags = {OA,WP},
 read = {true},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 citation_key = {Sampedro},
 private_publication = {false},
 abstract = {Background: Ayahuasca is a plant tea containing the psychedelic 5-HT2A agonist N,N-dimethyltryptamine and harmala monoamine-oxidase inhibitors. Acute administration leads to neurophysiological modifications in brain regions of the default mode network, purportedly through a glutamatergic mechanism. Post-acutely, ayahuasca potentiates mindfulness capacities in volunteers and induces rapid and sustained antidepressant effects in treatment-resistant patients. However, the mechanisms underlying these fast and maintained effects are poorly understood. Here, we investigated in an open-label uncontrolled study in 16 healthy volunteers ayahuasca-induced post-acute neurometabolic and connectivity modifications and their association with mindfulness measures. Methods: Using 1H-magnetic resonance spectroscopy and functional connectivity, we compared baseline and post-acute neurometabolites and seed-to-voxel connectivity in the posterior and anterior cingulate cortex after a single ayahuasca dose. Results: Magnetic resonance spectroscopy showed post-acute reductions in glutamate+glutamine, creatine, and N-acetylaspartate+N-acetylaspartylglutamate in the posterior cingulate cortex. Connectivity was increased between the posterior cingulate cortex and the anterior cingulate cortex, and between the anterior cingulate cortex and limbic structures in the right medial temporal lobe. Glutamate+glutamine reductions correlated with increases in the “nonjudging” subscale of the Five Facets Mindfulness Questionnaire. Increased anterior cingulate cortex-medial temporal lobe connectivity correlated with increased scores on the self-compassion questionnaire. Post-acute neural changes predicted sustained elevations in nonjudging 2 months later. Conclusions: These results support the involvement of glutamate neurotransmission in the effects of psychedelics in humans. They further suggest that neurometabolic changes in the posterior cingulate cortex, a key region within the default mode network, and increased connectivity between the anterior cingulate cortex and medial temporal lobe structures involved in emotion and memory potentially underlie the post-acute psychological effects of ayahuasca.},
 bibtype = {article},
 author = {Sampedro, Frederic and Revenga, Mario De La Fuente and Valle, Marta and Roberto, Natalia and Domínguez-Clavé, Elisabet and Elices, Matilde and Luna, Luís Eduardo and Crippa, José Alexandre S. and Hallak, Jaime Eduardo Cecilio and Araujo, Draulio Barros de and Friedlander, Pablo and Barker, Steven Andrew and Álvarez, Enrique and Soler, Joaquim and Pascual, Juan C. and Feilding, Amanda and Riba, Jordi},
 journal = {International Journal of Neuropsychopharmacology},
 number = {9}
}

@article{franzmeier_left_2017-1,
	title = {Left frontal cortex connectivity underlies cognitive reserve in prodromal {Alzheimer} disease},
	volume = {88},
	issn = {1526-632X (Electronic) 0028-3878 (Linking)},
	doi = {10.1212/WNL.0000000000003711},
	abstract = {OBJECTIVE: To test whether higher global functional connectivity of the left frontal cortex (LFC) in Alzheimer disease (AD) is associated with more years of education (a proxy of cognitive reserve [CR]) and mitigates the association between AD-related fluorodeoxyglucose (FDG)-PET hypometabolism and episodic memory. METHODS: Forty-four amyloid-PET-positive patients with amnestic mild cognitive impairment (MCI-Abeta+) and 24 amyloid-PET-negative healthy controls (HC) were included. Voxel-based linear regression analyses were used to test the association between years of education and FDG-PET in MCI-Abeta+, controlled for episodic memory performance. Global LFC (gLFC) connectivity was computed through seed-based resting-state fMRI correlations between the LFC (seed) and each voxel in the gray matter. In linear regression analyses, education as a predictor of gLFC connectivity and the interaction of gLFC connectivity x FDG-PET hypometabolism on episodic memory were tested. RESULTS: FDG-PET metabolism in the precuneus was reduced in MCI-Abeta+ compared to HC (p = 0.028), with stronger reductions observed in MCI-Abeta+ with more years of education (p = 0.006). In MCI-Abeta+, higher gLFC connectivity was associated with more years of education (p = 0.021). At higher levels of gLFC connectivity, the association between precuneus FDG-PET hypometabolism and lower memory performance was attenuated (p = 0.027). CONCLUSIONS: Higher gLFC connectivity is a functional substrate of CR that helps to maintain episodic memory relatively well in the face of emerging FDG-PET hypometabolism in early-stage AD.},
	number = {11},
	journal = {Neurology},
	author = {Franzmeier, N. and Duering, M. and Weiner, M. and Dichgans, M. and Ewers, M. and Alzheimer's Disease Neuroimaging, Initiative},
	month = mar,
	year = {2017},
	pmcid = {PMC5384837},
	pmid = {28188306},
	keywords = {Female, Humans, Male, Magnetic Resonance Imaging, Nerve Net/*pathology, Oxygen/blood, Neuropsychological Tests, Cognition Disorders/*etiology, Functional Laterality, Functional Laterality/*physiology, Alzheimer Disease/*complications/diagnostic imaging/*pathology, Chi-Square Distribution, Cognitive Reserve/*physiology, Epilepsy/diagnostic imaging/etiology, Fluorodeoxyglucose F18/metabolism, Frontal Lobe/diagnostic imaging/pathology, Positron-Emission Tomography, Prodromal Symptoms, Fluorodeoxyglucose F18, Cognition Disorders, Alzheimer Disease, Epilepsy, Frontal Lobe, Nerve Net, Cognitive Reserve, Oxygen},
	pages = {1054--1061},
}

Paper  doi  bibtex   

@article{DBLP:journals/tmi/RajchlLOKPBDRHK17,
  author    = {Martin Rajchl and
               Matthew C. H. Lee and
               Ozan Oktay and
               Konstantinos Kamnitsas and
               Jonathan Passerat{-}Palmbach and
               Wenjia Bai and
               Mellisa Damodaram and
               Mary A. Rutherford and
               Joseph V. Hajnal and
               Bernhard Kainz and
               Daniel Rueckert},
  title     = {DeepCut: Object Segmentation From Bounding Box Annotations Using Convolutional
               Neural Networks},
  journal   = {{IEEE} Trans. Med. Imaging},
  volume    = {36},
  number    = {2},
  pages     = {674--683},
  year      = {2017},
  url       = {https://doi.org/10.1109/TMI.2016.2621185},
  doi       = {10.1109/TMI.2016.2621185},
  timestamp = {Wed, 25 Sep 2019 01:00:00 +0200},
  biburl    = {https://dblp.org/rec/journals/tmi/RajchlLOKPBDRHK17.bib},
  bibsource = {dblp computer science bibliography, https://dblp.org}
}

Paper  doi  bibtex   

@article{el_marroun_prenatal_2016,
	title = {{PRENATAL} {EXPOSURE} {TO} {MATERNAL} {AND} {PATERNAL} {DEPRESSIVE} {SYMPTOMS} {AND} {BRAIN} {MORPHOLOGY}: {A} {POPULATION}-{BASED} {PROSPECTIVE} {NEUROIMAGING} {STUDY} {IN} {YOUNG} {CHILDREN}},
	volume = {33},
	issn = {10914269},
	url = {http://doi.wiley.com/10.1002/da.22524},
	doi = {10.1002/da.22524},
	number = {7},
	urldate = {2018-08-28},
	journal = {Depression and Anxiety},
	author = {El Marroun, Hanan and Tiemeier, Henning and Muetzel, Ryan L. and Thijssen, Sandra and van der Knaap, Noortje J. F. and Jaddoe, Vincent W. V. and Fernández, Guillén and Verhulst, Frank C. and White, Tonya J. H.},
	month = jul,
	year = {2016},
	note = {Publisher: Wiley-Blackwell},
	keywords = {brain morphology, depression, magnetic resonance imaging, paternal exposure, prenatal programing},
	pages = {658--666},
}

Paper  doi  abstract   bibtex   

@article{englund_evidence_2016,
	title = {Evidence that meniscus damage may be a component of osteoarthritis: {The} {Framingham} study.},
	volume = {24},
	issn = {1522-9653},
	shorttitle = {Evidence that meniscus damage may be a component of osteoarthritis},
	url = {http://dx.doi.org/10.1016%2Fj.joca.2015.08.005},
	doi = {10.1016/j.joca.2015.08.005},
	abstract = {OBJECTIVES: The etiology of degenerative meniscus tear is unclear but could be related to a generalized osteoarthritic disease process. We studied whether radiographic hand osteoarthritis (OA) is associated with meniscus damage.
METHODS: We examined 974 persons aged 50-90 years drawn via census tract data and random-digit dialing from Framingham, Massachusetts, United States. One reader assessed bilateral hand radiographs (30 joints) and another read frontal knee radiographs, all according to the Kellgren-Lawrence (KL) scale. A third reader assessed right knee 1.5-T magnetic resonance imaging (MRI) scans for meniscus damage. We calculated the prevalence of medial and/or lateral meniscus damage in those with one to two and three or more finger joints with radiographic OA (KL grade ≥2) compared to those without radiographic hand OA with adjustment for age, sex, and body mass index. We also evaluated the above association in persons without evidence of radiographic OA (KL grade 0) in their knee (n = 748).
RESULTS: The prevalence of meniscus damage in the knee of subjects with no, one to two, and three or more finger joints with OA was 24.9\%, 31.7\%, and 47.2\%, respectively. The adjusted prevalence ratio (PR) of having meniscus damage was significantly increased in those who had three or more finger joints with OA (1.40 [95\% confidence interval (CI) 1.11-1.77]). The estimate remained similar in persons without evidence of radiographic OA in their knee (PR, 1.42 [95\% CI 1.03-1.97]). The association was more robust for medial meniscus damage.
CONCLUSION: Results suggest a common non-age related etiologic pathway for both radiographic hand OA and meniscus damage.},
	language = {eng},
	number = {2},
	journal = {Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society},
	author = {Englund, M. and Haugen, I. K. and Guermazi, A. and Roemer, F. W. and Niu, J. and Neogi, T. and Aliabadi, P. and Felson, D. T.},
	month = feb,
	year = {2016},
	pmid = {26318660},
	pmcid = {PMC4724446},
	keywords = {Hand, Knee, Magnetic resonance imaging, Meniscus, Osteoarthritis, Radiography},
	pages = {270--273},
}

Paper  doi  abstract   bibtex   

@article{hanneman_assessment_2016,
	title = {Assessment of the precision and reproducibility of ventricular volume, function, and mass measurements with ferumoxytol-enhanced {4D} flow {MRI}},
	volume = {44},
	issn = {1522-2586},
	url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/jmri.25180},
	doi = {10.1002/jmri.25180},
	abstract = {Purpose To compare the precision and interobserver agreement of ventricular volume, function, and mass quantification by 3D time-resolved (4D) flow MRI relative to cine steady-state free precession (SSFP). Materials and Methods With Institutional Research Board approval, informed consent, and HIPAA compliance, 22 consecutive patients with congenital heart disease (CHD) (10 males, 6.4 ± 4.8 years) referred for 3T ferumoxytol-enhanced cardiac MRI were prospectively recruited. Complete ventricular coverage with standard 2D short-axis cine SSFP and whole chest coverage with axial 4D flow were obtained. Two blinded radiologists independently segmented images for left ventricular (LV) and right ventricular (RV) myocardium at end systole (ES) and end diastole (ED). Statistical analysis included linear regression, analysis of variance (ANOVA), Bland–Altman (BA) analysis, and intraclass correlation (ICC). Results Significant positive correlations were found between 4D flow and SSFP for ventricular volumes (r = 0.808–0.972, P {\textless} 0.001), ejection fraction (EF) (r = 0.900–928, P {\textless} 0.001), and mass (r = 0.884–0.934, P {\textless} 0.001). BA relative limits of agreement for both ventricles were between –52\% to 34\% for volumes, –29\% to 27\% for EF, and –41\% to 48\% for mass, with wider limits of agreement for the RV compared to the LV. There was no significant difference between techniques with respect to mean square difference of ED-ES mass for either LV (F = 2.05, P = 0.159) or RV (F = 0.625, P = 0.434). Interobserver agreement was moderate to good with both 4D flow (ICC 0.523–0.993) and SSFP (ICC 0.619–0.982), with overlapping confidence intervals. Conclusion Quantification of ventricular volume, function, and mass can be accomplished with 4D flow MRI with precision and interobserver agreement comparable to that of cine SSFP. J. Magn. Reson. Imaging 2016;44:383–392.},
	language = {en},
	number = {2},
	urldate = {2022-02-03},
	journal = {Journal of Magnetic Resonance Imaging},
	author = {Hanneman, Kate and Kino, Aya and Cheng, Joseph Y. and Alley, Marcus T. and Vasanawala, Shreyas S.},
	year = {2016},
	note = {\_eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1002/jmri.25180},
	keywords = {4D flow, magnetic resonance imaging, ventricular function, ventricular myocardium},
	pages = {383--392},
}

@article{nisenblat_imaging_2016,
	title = {Imaging modalities for the non-invasive diagnosis of endometriosis},
	volume = {2},
	issn = {1469-493X},
	doi = {10.1002/14651858.CD009591.pub2},
	abstract = {BACKGROUND: About 10\% of women of reproductive age suffer from endometriosis. Endometriosis is a costly chronic disease that causes pelvic pain and subfertility. Laparoscopy, the gold standard diagnostic test for endometriosis, is expensive and carries surgical risks. Currently, no non-invasive tests that can be used to accurately diagnose endometriosis are available in clinical practice. This is the first review of diagnostic test accuracy of imaging tests for endometriosis that uses Cochrane methods to provide an update on the rapidly expanding literature in this field.
OBJECTIVES: • To provide estimates of the diagnostic accuracy of imaging modalities for the diagnosis of pelvic endometriosis, ovarian endometriosis and deeply infiltrating endometriosis (DIE) versus surgical diagnosis as a reference standard.• To describe performance of imaging tests for mapping of deep endometriotic lesions in the pelvis at specific anatomical sites.Imaging tests were evaluated as replacement tests for diagnostic surgery and as triage tests that would assist decision making regarding diagnostic surgery for endometriosis.
SEARCH METHODS: We searched the following databases to 20 April 2015: MEDLINE, CENTRAL, EMBASE, CINAHL, PsycINFO, Web of Science, LILACS, OAIster, TRIP, ClinicalTrials.gov, MEDION, DARE, and PubMed. Searches were not restricted to a particular study design or language nor to specific publication dates. The search strategy incorporated words in the title, abstracts, text words across the record and medical subject headings (MeSH).
SELECTION CRITERIA: We considered published peer-reviewed cross-sectional studies and randomised controlled trials of any size that included prospectively recruited women of reproductive age suspected of having one or more of the following target conditions: endometrioma, pelvic endometriosis, DIE or endometriotic lesions at specific intrapelvic anatomical locations. We included studies that compared the diagnostic test accuracy of one or more imaging modalities versus findings of surgical visualisation of endometriotic lesions.
DATA COLLECTION AND ANALYSIS: Two review authors independently collected and performed a quality assessment of data from each study. For each imaging test, data were classified as positive or negative for surgical detection of endometriosis, and sensitivity and specificity estimates were calculated. If two or more tests were evaluated in the same cohort, each was considered as a separate data set. We used the bivariate model to obtain pooled estimates of sensitivity and specificity when sufficient data sets were available. Predetermined criteria for a clinically useful imaging test to replace diagnostic surgery included sensitivity ≥ 94\% and specificity ≥ 79\%. Criteria for triage tests were set at sensitivity ≥ 95\% and specificity ≥ 50\%, ruling out the diagnosis with a negative result (SnNout test - if sensitivity is high, a negative test rules out pathology) or at sensitivity ≥ 50\% with specificity ≥ 95\%, ruling in the diagnosis with a positive result (SpPin test - if specificity is high, a positive test rules in pathology).
MAIN RESULTS: We included 49 studies involving 4807 women: 13 studies evaluated pelvic endometriosis, 10 endometriomas and 15 DIE, and 33 studies addressed endometriosis at specific anatomical sites. Most studies were of poor methodological quality. The most studied modalities were transvaginal ultrasound (TVUS) and magnetic resonance imaging (MRI), with outcome measures commonly demonstrating diversity in diagnostic estimates; however, sources of heterogeneity could not be reliably determined. No imaging test met the criteria for a replacement or triage test for detecting pelvic endometriosis, albeit TVUS approached the criteria for a SpPin triage test. For endometrioma, TVUS (eight studies, 765 participants; sensitivity 0.93 (95\% confidence interval (CI) 0.87, 0.99), specificity 0.96 (95\% CI 0.92, 0.99)) qualified as a SpPin triage test and approached the criteria for a replacement and SnNout triage test, whereas MRI (three studies, 179 participants; sensitivity 0.95 (95\% CI 0.90, 1.00), specificity 0.91 (95\% CI 0.86, 0.97)) met the criteria for a replacement and SnNout triage test and approached the criteria for a SpPin test. For DIE, TVUS (nine studies, 12 data sets, 934 participants; sensitivity 0.79 (95\% CI 0.69, 0.89) and specificity 0.94 (95\% CI 0.88, 1.00)) approached the criteria for a SpPin triage test, and MRI (six studies, seven data sets, 266 participants; sensitivity 0.94 (95\% CI 0.90, 0.97), specificity 0.77 (95\% CI 0.44, 1.00)) approached the criteria for a replacement and SnNout triage test. Other imaging tests assessed in small individual studies could not be statistically evaluated.TVUS met the criteria for a SpPin triage test in mapping DIE to uterosacral ligaments, rectovaginal septum, vaginal wall, pouch of Douglas (POD) and rectosigmoid. MRI met the criteria for a SpPin triage test for POD and vaginal and rectosigmoid endometriosis. Transrectal ultrasonography (TRUS) might qualify as a SpPin triage test for rectosigmoid involvement but could not be adequately assessed for other anatomical sites because heterogeneous data were scant. Multi-detector computerised tomography enema (MDCT-e) displayed the highest diagnostic performance for rectosigmoid and other bowel endometriosis and met the criteria for both SpPin and SnNout triage tests, but studies were too few to provide meaningful results.Diagnostic accuracies were higher for TVUS with bowel preparation (TVUS-BP) and rectal water contrast (RWC-TVS) and for 3.0TMRI than for conventional methods, although the paucity of studies precluded statistical evaluation.
AUTHORS' CONCLUSIONS: None of the evaluated imaging modalities were able to detect overall pelvic endometriosis with enough accuracy that they would be suggested to replace surgery. Specifically for endometrioma, TVUS qualified as a SpPin triage test. MRI displayed sufficient accuracy to suggest utility as a replacement test, but the data were too scant to permit meaningful conclusions. TVUS could be used clinically to identify additional anatomical sites of DIE compared with MRI, thus facilitating preoperative planning. Rectosigmoid endometriosis was the only site that could be accurately mapped by using TVUS, TRUS, MRI or MDCT-e. Studies evaluating recent advances in imaging modalities such as TVUS-BP, RWC-TVS, 3.0TMRI and MDCT-e were observed to have high diagnostic accuracies but were too few to allow prudent evaluation of their diagnostic role. In view of the low quality of most of the included studies, the findings of this review should be interpreted with caution. Future well-designed diagnostic studies undertaken to compare imaging tests for diagnostic test accuracy and costs are recommended.},
	language = {eng},
	journal = {The Cochrane Database of Systematic Reviews},
	author = {Nisenblat, Vicki and Bossuyt, Patrick M. M. and Farquhar, Cindy and Johnson, Neil and Hull, M. Louise},
	year = {2016},
	pmid = {26919512},
	keywords = {Chronic Disease, Cross-Sectional Studies, Diagnostic Imaging, Endometriosis, Female, Humans, Magnetic Resonance Imaging, Ovarian Diseases, Pelvis, Positron-Emission Tomography, Randomized Controlled Trials as Topic, Sensitivity and Specificity, Ultrasonography},
	pages = {CD009591}
}

Website  abstract   bibtex   

@article{
 title = {Prefrontal cortical thinning in HIV infection is associated with impaired striatal functioning},
 type = {article},
 year = {2016},
 identifiers = {[object Object]},
 keywords = {Adult,Anticipation, Psychological,Atrophy,Cortex,Female,HIV,HIV Infections,Humans,Inhibition,Inhibition, Psychological,Magnetic Resonance Imaging,Male,Neostriatum,Prefrontal Cortex,Striatum,Young Adult,fMRI},
 pages = {643-651},
 volume = {123},
 websites = {http://www.ncbi.nlm.nih.gov/pubmed/27173383},
 id = {d7fe6fe0-8a37-3c4f-933f-516819ee81c4},
 created = {2020-09-17T09:27:45.198Z},
 file_attached = {false},
 profile_id = {20f87055-ac78-3c65-9cf5-216a3558d16a},
 group_id = {14ca8526-77d5-34fd-89de-e48cae5e6ee2},
 last_modified = {2020-09-17T09:27:45.198Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 source_type = {JOUR},
 language = {eng},
 private_publication = {false},
 abstract = {While cortical thinning has been associated with HIV infection, it is unclear whether this reflects a direct effect of the virus, whether it is related to disruption of subcortical function or whether it is better explained by epiphenomena, such as drug abuse or comorbid medical conditions. The present study investigated the relationship between cortical thickness and subcortical function in HIV+ patients. Specifically, we examined the relationship between prefrontal cortical thickness and striatal function. Twenty-three largely treatment naïve, non-substance abusing HIV+ participants and 19 healthy controls matched for age, gender, and educational status were included. Cortical morphometry was performed using FreeSurfer software analysis. Striatal function was measured during an fMRI stop-signal anticipation task known to engage the striatum. Any cortical regions showing significant thinning were entered as dependent variables into a single linear regression model which included subcortical function, age, CD4 count, and a measure of global cognitive performance as independent predictors. The only cortical region that was significantly reduced after correction for multiple comparisons was the right superior frontal gyrus. Striatal activity was found to independently predict superior frontal gyral cortical thickness. While cortical thinning in HIV infection is likely multifactorial, viral induced subcortical dysfunction appears to play a role.},
 bibtype = {article},
 author = {du Plessis, Stéfan and Vink, Matthijs and Joska, John A and Koutsilieri, Eleni and Bagadia, Asif and Stein, Dan J and Emsley, Robin},
 journal = {Journal of Neural Transmission (Vienna, Austria: 1996)},
 number = {6}
}

@article{rancan_mri_2016,
	title = {{MRI} {CEST} at {1T} with large µeff {Ln}(3+) complexes {T} m(3+)-{HPDO3A}: {An} efficient {MRI} {pH} reporter},
	volume = {75},
	issn = {1522-2594},
	shorttitle = {{MRI} {CEST} at {1T} with large µeff {Ln}(3+) complexes {T} m(3+)-{HPDO3A}},
	doi = {10.1002/mrm.25589},
	abstract = {PURPOSE: Chemical exchange saturation transfer (CEST) sensitivity relies on the prototropic exchange rate kex between the agent and the "bulk" water protons. To exploit large kex, a large frequency separation (Δω) between the pools of exchanging protons is necessary. For this reason, high magnetic fields are preferred. Herein it is shown that the use of paramagnetic CEST agents based on lanthanide (III) ions with large effective magnetic moments allows the carrying out of CEST experiments at the relatively low field strength of 1 tesla (T).
METHODS: Measurements were performed on a 1T MR-scanner using continuous wave (cw)-presaturation with a spin echo sequence. ParaCEST complexes have been synthetized by mixing the ligand and Ln(III)Cl3 in a stoichiometric ratio at room temperature and pH 7.
RESULTS: Different lanthanide chelates were investigated (Tm-, Dy-, Yb-, Eu-HPDO3A, and Eu-DOTAMGly). Ratiometric (Tm-HPDO3A) and selective detection (Eu-DOTAMGly and Tm-HPDO3A) experiments have been proven feasible in vivo.
CONCLUSION: In vitro experiments demonstrated the feasibility of the CEST methodology at 1T for nearly every paraCEST candidate under investigation, except for Eu-HPDO3A. Among the studied compounds, Tm-HPDO3A proved suitable for the application of a ratiometric method for assessing pH both in vitro and in vivo.},
	language = {eng},
	number = {1},
	journal = {Magnetic Resonance in Medicine},
	author = {Rancan, Giaime and Delli Castelli, Daniela and Aime, Silvio},
	month = jan,
	year = {2016},
	pmid = {25651986},
	keywords = {Animals, CEST, Contrast Media, Feasibility Studies, HPDO3A, Heterocyclic Compounds, 1-Ring, Hydrogen-Ion Concentration, Lanthanoid Series Elements, Magnetic Resonance Imaging, Phantoms, Imaging, Rats, Reproducibility of Results, Sensitivity and Specificity, Urinary Bladder, low-field CEST, pH mapping, paraCEST},
	pages = {329--336},
}

@article{wendler_irreversible_2016,
	title = {Irreversible {Electroporation} of {Prostate} {Cancer}: {Patient}-{Specific} {Pretreatment} {Simulation} by {Electric} {Field} {Measurement} in a {3D} {Bioprinted} {Textured} {Prostate} {Cancer} {Model} to {Achieve} {Optimal} {Electroporation} {Parameters} for {Image}-{Guided} {Focal} {Ablation}.},
	volume = {39},
	issn = {1432-086X 0174-1551},
	doi = {10.1007/s00270-016-1390-6},
	language = {eng},
	number = {11},
	journal = {Cardiovascular and interventional radiology},
	author = {Wendler, Johann Jakob and Klink, Fabian and Seifert, Sven and Fischbach, Frank and Jandrig, Burkhard and Porsch, Markus and Pech, Maciej and Baumunk, Daniel and Ricke, Jens and Schostak, Martin and Liehr, Uwe-Bernd},
	month = nov,
	year = {2016},
	pmid = {27256102},
	keywords = {*Models, Biological, *Printing, Three-Dimensional, Catheter Ablation/methods, Electroporation/*methods, Humans, Magnetic Resonance Imaging, Interventional/*methods, Male, Preoperative Care/*methods, Prostate/diagnostic imaging/surgery, Prostatic Neoplasms/diagnostic imaging/*surgery},
	pages = {1668--1671},
}

@article{hennion_functional_2016,
	title = {A functional magnetic resonance imaging investigation of theory of mind impairments in patients with temporal lobe epilepsy},
	volume = {93},
	issn = {1873-3514},
	doi = {10.1016/j.neuropsychologia.2016.11.007},
	abstract = {Although patients with mesial temporal lobe epilepsy (mTLE) are known to have theory of mind (ToM) impairments, the latter's neural functional bases have yet to be explored. We used functional magnetic resonance imaging (fMRI) to gain insights into the neural dysfunction associated with ToM impairments in patients with mTLE. Twenty-five patients (12 and 13 with right and left mTLE, respectively) and 25 healthy controls performed the "animated shapes" task during fMRI. This complex ToM task requires both explicit reasoning about mental states and implicit processing of information on biological motion and action. The animated shapes evoke both ToM and non-ToM interaction perception, and the corresponding neural activation patterns were compared. Behavioral performance (i.e. categorization of the interactions) was also recorded. Relative to healthy controls, both patients with right and left mTLE were impaired in categorizing ToM interactions. The fMRI results showed that both patients with right and left mTLE had less intense neural activation (relative to controls) in regions involved in the implicit component of ToM processes (i.e. the fusiform gyrus in patients with right mTLE and the supplementary motor area in patients with left mTLE). In patients with right mTLE, we also observed more intense activation (relative to controls) in regions involved in the explicit component of ToM processes (i.e. the dorsal medial prefrontal cortex); age at onset of epilepsy also mediated activation in regions involved in the explicit component (i.e. the ventral medial prefrontal cortex and the temporoparietal junction). Patients with left mTLE displayed greater activation of the contralateral mesial regions (relative to controls); we speculate that this may correspond to the deployment of a compensatory mechanism. This study provides insights into the disturbances of the implicit/explicit ToM neural network in patients with mTLE. These impairments in the ToM neural network depend on clinical characteristics, such as the laterality (right or left mTLE) and the age at onset of epilepsy.},
	language = {eng},
	number = {Pt A},
	journal = {Neuropsychologia},
	author = {Hennion, Sophie and Delbeuck, Xavier and Koelkebeck, Katja and Brion, Marine and Tyvaert, Louise and Plomhause, Lucie and Derambure, Philippe and Lopes, Renaud and Szurhaj, William},
	month = dec,
	year = {2016},
	pmid = {27847305},
	keywords = {Humans, Magnetic Resonance Imaging, Age of Onset, Female, Male, Brain, Neuropsychological Tests, Adult, Time Factors, Regression Analysis, Cognitive Dysfunction, Pattern Recognition, Visual, Theory of Mind, Brain Mapping, Functional Laterality, Epilepsy, Temporal Lobe, Animated shapes, Functional imaging, Judgment, Mesial temporal epilepsy, Motion Perception, Theory of mind},
	pages = {271--279}
}

@inproceedings{ohldag_time_2015,
	title = {Time resolved magnetic imaging at {10Ghz} and beyond},
	doi = {10.1109/INTMAG.2015.7157028},
	abstract = {Summary form only given. Understanding magnetic properties at ultrafast timescales is crucial for the development of new generations of magnetic devices. Such devices will employ the spin torque or spin Hall effect, whose manifestation at the nanoscale is not yet sufficiently understood, which is why studies addressing these effects are of great fundamental significance as well. The samples of interest are often thin film magnetic multilayers with thicknesses in the range of a atomic layers. This fact alone presents a sensitivity challenge in STXM microscopy, which is more suited toward studying thicker samples. In addition the relevant time scale is of the order of 10 ps, which is well below the typical x-ray pulse length of 50-100 ps. Altogether this means that pushing the time resolution of a synchrotron x-ray microscopy experiment is synonymous with improving the signal to noise ratio on the detector and providing stable, low jitter excitation to not further dilute the already small magnetic signals. To achieve the required stability and sensitivity the SSRL STXM is equipped with a single photon counting electronics that effectively allows us to use a double lock-in detection at 476MHz (the x-ray pulse frequency) and 1.28MHz (the synchrotron revelation frequency). The pulsed or continuous sample excitation source is synchronized with the synchrotron source with a few picosecond drift over 24 hours (see figure). This setup currently allows us to achieve a signal to noise ratio of better than 10000, enabling us to detect miniscule variations of the x-ray absorption cross section. In this talk I will describe the time resolved STXM setup developed at SSRL and present firsts results that have been obtained using the instrument in collaboration with an outstanding group of external users. The instrument operates in ultra high vacuum ( 10-8torr) and allows us to apply electrical pulses to our samples that can be placed in out of plane magnetic fields up to 0.8 Tesla - r in plane magnetic fields up to 0.3 Tesla. We have used the instrument to successfully image spin waves excited in spin-torque and spin Hall oscillators with nano contacts of the size of 100nm. We also succeeded in imaging different excitation modes of magnetic samples in ferromagnetic resonance at 9.6GHz excitation frequency, where the opening angle of the precession cone is of the order of 10mrad. The facility that is dedicated to ultrafast studies of materials under electric and magnetic fields is open to general users who are interested in this field.},
	booktitle = {2015 {IEEE} {Magnetics} {Conference} ({INTERMAG})},
	author = {Ohldag, H. and Bonetti, S. and Kukreja, R. and Frisch, J. and Duerr, H. and Stoehr, J.},
	year = {2015},
	keywords = {Ferromagnetic Resonance, Magnetic fields, Magnetic resonance imaging, Microscopy, electric field, electrical pulses, excitation frequency, excitation modes, frequency 9.6 GHz, high-speed techniques, in plane magnetic fields, magnetic multilayers, magnetoelectronics, nanocontacts, opening angle, oscillators, out of plane magnetic fields, precession cone, sensitivity, spin Hall effect, spin Hall oscillators, spin waves, spin-torque, time resolved STXM setup, time resolved magnetic imaging, torque, x-ray microscopy},
	pages = {1--1},
}

@article{
 title = {Daily Marijuana Use Is Not Associated with Brain Morphometric Measures in Adolescents or Adults},
 type = {article},
 year = {2015},
 identifiers = {[object Object]},
 keywords = {Adolescent,Adult,Aging,Brain,Brain: pathology,Dose-Response Relationship, Drug,Female,Humans,Image Processing, Computer-Assisted,Magnetic Resonance Imaging,Male,Marijuana Smoking,Marijuana Smoking: pathology,Retrospective Studies,Statistics, Nonparametric,Young Adult},
 id = {16df742c-e4c4-381b-a7c2-b594d11f069a},
 created = {2016-01-05T19:45:08.000Z},
 file_attached = {false},
 profile_id = {50a856f4-e41b-3395-a32c-35f3a97eb9f9},
 group_id = {41f9b5d2-912d-3281-b756-e2d6e7ccfec5},
 last_modified = {2016-01-05T19:45:08.000Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 abstract = {Recent research has suggested that marijuana use is associated with volumetric and shape differences in subcortical structures, including the nucleus accumbens and amygdala, in a dose-dependent fashion. Replication of such results in well controlled studies is essential to clarify the effects of marijuana. To that end, this retrospective study examined brain morphology in a sample of adult daily marijuana users (n = 29) versus nonusers (n = 29) and a sample of adolescent daily users (n = 50) versus nonusers (n = 50). Groups were matched on a critical confounding variable, alcohol use, to a far greater degree than in previously published studies. We acquired high-resolution MRI scans, and investigated group differences in gray matter using voxel-based morphometry, surface-based morphometry, and shape analysis in structures suggested to be associated with marijuana use, as follows: the nucleus accumbens, amygdala, hippocampus, and cerebellum. No statistically significant differences were found between daily users and nonusers on volume or shape in the regions of interest. Effect sizes suggest that the failure to find differences was not due to a lack of statistical power, but rather was due to the lack of even a modest effect. In sum, the results indicate that, when carefully controlling for alcohol use, gender, age, and other variables, there is no association between marijuana use and standard volumetric or shape measurements of subcortical structures. },
 bibtype = {article},
 author = {Weiland, B. J. and Thayer, R. E. and Depue, B. E. and Sabbineni, a. and Bryan, a. D. and Hutchison, K. E.},
 journal = {Journal of Neuroscience}
}

@article{arnal_human_2015,
	title = {Human screams occupy a privileged niche in the communication soundscape},
	volume = {25},
	issn = {1879-0445},
	doi = {10.1016/j.cub.2015.06.043},
	abstract = {Screaming is arguably one of the most relevant communication signals for survival in humans. Despite their practical relevance and their theoretical significance as innate [1] and virtually universal [2, 3] vocalizations, what makes screams a unique signal and how they are processed is not known. Here, we use acoustic analyses, psychophysical experiments, and neuroimaging to isolate those features that confer to screams their alarming nature, and we track their processing in the human brain. Using the modulation power spectrum (MPS [4, 5]), a recently developed, neurally informed characterization of sounds, we demonstrate that human screams cluster within restricted portion of the acoustic space (between ∼30 and 150 Hz modulation rates) that corresponds to a well-known perceptual attribute, roughness. In contrast to the received view that roughness is irrelevant for communication [6], our data reveal that the acoustic space occupied by the rough vocal regime is segregated from other signals, including speech, a pre-requisite to avoid false alarms in normal vocal communication. We show that roughness is present in natural alarm signals as well as in artificial alarms and that the presence of roughness in sounds boosts their detection in various tasks. Using fMRI, we show that acoustic roughness engages subcortical structures critical to rapidly appraise danger. Altogether, these data demonstrate that screams occupy a privileged acoustic niche that, being separated from other communication signals, ensures their biological and ultimately social efficiency.},
	language = {eng},
	number = {15},
	journal = {Current biology: CB},
	author = {Arnal, Luc H. and Flinker, Adeen and Kleinschmidt, Andreas and Giraud, Anne-Lise and Poeppel, David},
	month = aug,
	year = {2015},
	pmid = {26190070},
	pmcid = {PMC4562283},
	keywords = {Acoustic Stimulation, Adult, Female, Humans, Magnetic Resonance Imaging, Male, Sound, Speech Acoustics, Speech Intelligibility, Speech Perception, Young Adult},
	pages = {2051--2056},
}

Paper  abstract   bibtex   

@article{critchley_slow_2015,
	title = {Slow breathing and hypoxic challenge: cardiorespiratory consequences and their central neural substrates},
	volume = {10},
	issn = {1932-6203},
	url = {https://www.ncbi.nlm.nih.gov/pubmed/25973923},
	abstract = {Controlled slow breathing (at 6/min, a rate frequently adopted during yoga practice) can benefit cardiovascular function, including responses to hypoxia. We tested the neural substrates of cardiorespiratory control in humans during volitional controlled breathing and hypoxic challenge using functional magnetic resonance imaging (fMRI). Twenty healthy volunteers were scanned during paced (slow and normal rate) breathing and during spontaneous breathing of normoxic and hypoxic (13\% inspired O2) air. Cardiovascular and respiratory measures were acquired concurrently, including beat-to-beat blood pressure from a subset of participants (N = 7). Slow breathing was associated with increased tidal ventilatory volume. Induced hypoxia raised heart rate and suppressed heart rate variability. Within the brain, slow breathing activated dorsal pons, periaqueductal grey matter, cerebellum, hypothalamus, thalamus and lateral and anterior insular cortices. Blocks of hypoxia activated mid pons, bilateral amygdalae, anterior insular and occipitotemporal cortices. Interaction between slow breathing and hypoxia was expressed in ventral striatal and frontal polar activity. Across conditions, within brainstem, dorsal medullary and pontine activity correlated with tidal volume and inversely with heart rate. Activity in rostroventral medulla correlated with beat-to-beat blood pressure and heart rate variability. Widespread insula and striatal activity tracked decreases in heart rate, while subregions of insular cortex correlated with momentary increases in tidal volume. Our findings define slow breathing effects on central and cardiovascular responses to hypoxic challenge. They highlight the recruitment of discrete brainstem nuclei to cardiorespiratory control, and the engagement of corticostriatal circuitry in support of physiological responses that accompany breathing regulation during hypoxic challenge.},
	language = {eng},
	number = {5},
	urldate = {0005-01-01},
	journal = {PloS one},
	author = {Critchley, Hugo D and Nicotra, Alessia and Chiesa, Patrizia A and Nagai, Yoko and Gray, Marcus A and Minati, Ludovico and Bernardi, Luciano},
	year = {2015},
	keywords = {*Respiration, Adult, Blood Pressure, Brain/*physiology, Female, Heart Rate, Humans, Hypoxia/metabolism/*physiopathology, Magnetic Resonance Imaging, Male, Middle Aged, Oxygen/*metabolism, Pulmonary Ventilation, Respiration, Tidal Volume, Young Adult},
	pages = {e0127082--e0127082},
}

@article{rizzitelli_vivo_2014,
	title = {In vivo {MRI} visualization of release from liposomes triggered by local application of pulsed low-intensity non-focused ultrasound},
	volume = {10},
	issn = {1549-9642},
	doi = {10.1016/j.nano.2014.03.012},
	abstract = {The work aimed at developing a MRI-guided protocol for the visualization of the release of material entrapped in liposomes stimulated by the local application of pulsed low-intensity non-focused ultrasound (pLINFU). The task was achieved by formulating liposomes filled up with the clinically approved paramagnetic agent gadoteridol, because the release of the agent from the nanovesicles is accompanied by a significant MRI signal enhancement. The protocol was validated in vivo on mice-bearing subcutaneous syngeneic B16 melanoma and i.v. injected with the paramagnetic liposomes. Upon exposing tumor to pLINFU (3MHz, insonation time 2min, duty cycle 50\%) few minutes after liposomes injection, a signal enhancement of ca. 35\% was detected. The effective release of the agent was confirmed by the strong enhancement measured in kidneys calyx and bladder due to the rapid renal excretion of the agent released in the tumor.
FROM THE CLINICAL EDITOR: In this paper, a pulsed low-intensity non-focused ultrasound-based technique was used to release a paramagnetic MRI contrast agent from liposomes, demonstrating the feasibility of this triggered release system in a mouse melanoma model for future research applications.},
	language = {eng},
	number = {5},
	journal = {Nanomedicine: Nanotechnology, Biology, and Medicine},
	author = {Rizzitelli, Silvia and Giustetto, Pierangela and Boffa, Cinzia and Delli Castelli, Daniela and Cutrin, Juan Carlos and Aime, Silvio and Terreno, Enzo},
	month = jul,
	year = {2014},
	pmid = {24657833},
	keywords = {Contrast Media, Drug release, Liposomes, MRI, Magnetic Resonance Imaging, Theranosis, Ultrasound},
	pages = {901--904},
}

@article{vytal_sustained_2014,
	title = {Sustained anxiety increases amygdala-dorsomedial prefrontal coupling: a mechanism for maintaining an anxious state in healthy adults.},
	volume = {39},
	copyright = {All rights reserved},
	issn = {1488-2434 1180-4882},
	doi = {10.1503/jpn.130145},
	abstract = {BACKGROUND: Neuroimaging research has traditionally explored fear and anxiety in response to discrete threat cues (e.g., during fear conditioning). However,  anxiety is a sustained aversive state that can persist in the absence of discrete  threats. Little is known about mechanisms that maintain anxiety states over a  prolonged period. Here, we used a robust translational paradigm (threat of shock)  to induce sustained anxiety. Recent translational work has implicated an  amygdala-prefrontal cortex (PFC) circuit in the maintenance of anxiety in  rodents. To explore the functional homologues of this circuitry in humans, we  used a novel paradigm to examine the impact of sustained anticipatory anxiety on  amygdala-PFC intrinsic connectivity. METHODS: Task-independent fMRI data were  collected in healthy participants during long-duration periods of shock  anticipation and safety. We examined intrinsic functional connectivity. RESULTS:  Our study involved 20 healthy participants. During sustained anxiety, amygdala  activity was positively coupled with dorsomedial PFC (DMPFC) activity. High trait  anxiety was associated with increased amygdala-DMPFC coupling. In addition,  induced anxiety was associated with positive coupling between regions involved in  defensive responding, and decreased coupling between regions involved in  emotional control and the default mode network. LIMITATIONS: Inferences regarding  anxious pathology should be made with caution because this study was conducted in  healthy participants. CONCLUSION: Findings suggest that anticipatory anxiety  increases intrinsic amygdala-DMPFC coupling and that the DMPFC may serve as a  functional homologue for the rodent prefrontal regions by sustaining anxiety.  Future research may use this defensive neural context to identify biomarkers of  risk for anxious pathology and target these circuits for therapeutic  intervention.},
	language = {eng},
	number = {5},
	journal = {Journal of psychiatry \& neuroscience : JPN},
	author = {Vytal, Katherine E. and Overstreet, Cassie and Charney, Danielle R. and Robinson, Oliver J. and Grillon, Christian},
	month = sep,
	year = {2014},
	pmid = {24886788},
	pmcid = {PMC4160361},
	note = {Place: Canada},
	keywords = {Adult, Amygdala/*physiopathology, Anticipation, Anticipation, Psychological/physiology, Anxiety/*physiopathology, Brain Mapping, Electroshock, Fear/physiology, Female, Humans, Magnetic Resonance Imaging, Male, Neural Pathways/physiopathology, Neuropsychological Tests, Personality, Prefrontal Cortex/*physiopathology, Psychological/physiology, Psychophysics, Young Adult},
	pages = {321--329},
}

Paper  abstract   bibtex   

@article{
 id = {a3662ba2-1207-3a5a-b1d3-9b382873adcc},
 title = {Advances in the understanding of the pathophysiology and management of aortic stenosis: role of novel imaging techniques.},
 type = {article},
 year = {2014},
 identifiers = {[object Object]},
 keywords = {Aortic Valve Stenosis,Aortic Valve Stenosis: diagnosis,Aortic Valve Stenosis: physiopathology,Aortic Valve Stenosis: therapy,Cardiac Imaging Techniques,Cardiac Imaging Techniques: methods,Echocardiography,Exercise,Humans,Magnetic Resonance Imaging,Meglumine,Meglumine: analogs & derivatives,Meglumine: diagnostic use,Organometallic Compounds,Organometallic Compounds: diagnostic use,Positron-Emission Tomography,Spectrum Analysis,Tomography, X-Ray Computed},
 created = {2015-03-04T10:21:07.000Z},
 pages = {994-1003},
 volume = {30},
 websites = {http://www.sciencedirect.com/science/article/pii/S0828282X14001469},
 month = {9},
 accessed = {2015-03-04},
 file_attached = {true},
 profile_id = {b5c74ca0-0e1c-3768-8aaa-5b327da36472},
 last_modified = {2015-03-13T13:53:09.000Z},
 tags = {aortic stenosis},
 read = {false},
 starred = {false},
 authored = {true},
 confirmed = {true},
 hidden = {false},
 abstract = {The management of asymptomatic patients with aortic stenosis (AS) is controversial and the mechanisms leading to symptom generation and adverse outcome are not fully understood. Novel imaging techniques offer a noninvasive tool for in vivo assessment of AS and its pathophysiological consequences on the myocardium. Exercise echocardiography provides insight into the mechanisms responsible for exercise limitation and symptom generation. Speckle tracking allows the detection of reduced myocardial strain, which is associated with adverse events in asymptomatic patients. Computed tomography scanning can accurately quantify valve calcification and is associated with disease severity. Positron emission tomography/computed tomography imaging has the potential to monitor disease activity (inflammation and microcalcification) for the first time. Cardiac magnetic resonance (CMR) imaging uniquely allows tissue characterization with identification of fibrosis, a key characteristic of failing myocardium. T1 mapping allows estimation of diffuse interstitial fibrosis and late gadolinium enhancement demonstrates focal fibrosis/scarring. Myocardial steatosis, assessed using CMR spectroscopy, is increased in severe AS and might contribute to myocardial dysfunction. Positron emission tomography and CMR imaging can quantify myocardial blood flow and assess microvascular dysfunction, which might contribute to symptom development and myocardial remodelling. These novel imaging techniques are now being assessed in prospective prognostic studies that will clarify their utility in risk stratification in AS, and lead to improved management and outcomes for these patients.},
 bibtype = {article},
 author = {Singh, Anvesha and Steadman, Christopher D and McCann, Gerry P},
 journal = {The Canadian journal of cardiology},
 number = {9}
}

Paper  doi  abstract   bibtex   

@article{ sommer_frameless_2014,
  title = {Frameless stereotactic functional neuronavigation combined with intraoperative magnetic resonance imaging as a strategy in highly eloquent located tumors causing epilepsy.},
  volume = {92},
  url = {http://www.ncbi.nlm.nih.gov/pubmed/24356382},
  doi = {10.1159/000355216},
  abstract = {BACKGROUND: Intractable epilepsy due to tumors located in highly eloquent brain regions is often considered surgically inaccessible because of a high risk of postoperative neurological deterioration. Intraoperative MRI and functional navigation contribute to overcome this problem. OBJECTIVES: To retrospectively investigate the long-term results and impact of functional neuronavigation and 1.5-tesla intraoperative MRI on patients who underwent surgery of tumors associated with epilepsy located close to or within eloquent brain areas. METHODS: Nineteen patients (9 female, 10 male, mean age 41.4 ± 13.4 years, 11 low-grade and 8 high-grade glial tumors) were evaluated preoperatively using BOLD imaging, diffusion-tensor imaging tractography and magnetoencephalography. Functional data were implemented into neuronavigation in this multimodal approach. RESULTS: In 14 of 19 patients (74%), complete resection was achieved, and in 5 patients significant tumor volume reduction was accomplished. Eight of 14 (57%) complete resections were achieved only by performing an intraoperative image update. Neurological deterioration was found permanently in 2 patients. After a mean follow-up of 43.8 ± 23.8 months, 15 patients (79%) became seizure free (Engel class Ia). CONCLUSIONS: Despite the highly eloquent location of tumors causing intractable epilepsy, our multimodal approach led to complete resection in more than two-thirds of patients with an acceptable neurological morbidity and excellent long-term seizure control.},
  number = {1},
  journal = {Stereotactic and functional neurosurgery},
  author = {Sommer, Bjoern and Grummich, Peter and Hamer, Hajo and Bluemcke, Ingmar and Coras, Roland and Buchfelder, Michael and Roessler, Karl},
  month = {January},
  year = {2014},
  keywords = {Adult, Brain Neoplasms, Brain Neoplasms: complications, Brain Neoplasms: pathology, Brain Neoplasms: surgery, Cerebral Cortex, Cerebral Cortex: pathology, Electroencephalography, Epilepsy, Epilepsy: epidemiology, Epilepsy: etiology, Female, Follow-Up Studies, Humans, Incidence, Intraoperative Period, Magnetic Resonance Imaging, Magnetic Resonance Imaging: methods, Male, Middle Aged, Neuronavigation, Neuronavigation: methods, Neurosurgical Procedures, Neurosurgical Procedures: methods, Retrospective Studies, Treatment Outcome},
  pages = {59--67}
}

Paper  doi  bibtex   

@article{robinson_role_2013,
	title = {The role of serotonin in the neurocircuitry of negative affective bias: {Serotonergic} modulation of the dorsal medial prefrontal-amygdala ‘aversive amplification’ circuit},
	volume = {78},
	copyright = {All rights reserved},
	issn = {1053-8119},
	shorttitle = {The role of serotonin in the neurocircuitry of negative affective bias: {Serotonergic} modulation of the dorsal medial prefrontal-amygdala ‘aversive amplification’ circuit},
	url = {http://www.sciencedirect.com/science/article/pii/S1053811913003303},
	doi = {10.1016/j.neuroimage.2013.03.075},
	journal = {Neuroimage},
	author = {Robinson, Oliver J. and Overstreet, Cassie and Allen, Philip S. and Letkiewicz, Alison and Vytal, Katherine and Pine, Daniel S. and Grillon, Christian},
	year = {2013},
	note = {0},
	keywords = {ATD, Adult, Affect/drug effects/physiology, Affective Symptoms, Amygdala, Amygdala/*metabolism/physiopathology, Anxiety/metabolism/physiopathology, Aversive amplification, Bias, Computer-Assisted, Cross-Over Studies, DMPFC, Depression/metabolism/physiopathology, Double-Blind Method, Emotions/drug effects/physiology, Female, Humans, Image Interpretation, Image Interpretation, Computer-Assisted, Magnetic Resonance Imaging, Male, Negative bias, Neural Pathways/*metabolism/physiopathology, Prefrontal Cortex/*metabolism/physiopathology, Serotonin Receptor Agonists/pharmacology, Serotonin/*metabolism, Tryptophan/pharmacology, serotonin},
	pages = {217--223},
}

@article{zieren_education_2013,
	title = {Education modifies the relation of vascular pathology to cognitive function: cognitive reserve in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy},
	volume = {34},
	issn = {1558-1497 (Electronic) 0197-4580 (Linking)},
	doi = {10.1016/j.neurobiolaging.2012.04.019},
	abstract = {A clinical impact of cognitive reserve (CR) has been demonstrated in Alzheimer's disease, whereas its role in vascular cognitive impairment (VCI) is largely unknown. In this study, we investigated the impact of CR in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a genetic variant of pure VCI. A total of 247 NOTCH3 mutation carriers from a two-center study were investigated using detailed neuropsychological and neuroimaging protocols. CR was operationalized as years of formal education. Brain pathology was assessed by MRI using normalized brain volume and lacunar lesion volume as proxies. Multivariate analyses were done for each structural measure with scores of processing speed, executive function, and memory as dependent variables. Additional linear regression models were conducted with interaction terms for education x brain volume and education x lacunar lesion volume. Education had an independent impact on cognitive performance in subjects with mild and moderate degrees of brain pathology, whereas there was no significant influence of education on cognition in patients with severe MRI changes. This interaction was found for processing speed, the cognitive domain most impaired in our patients. Our findings demonstrate an interaction of education and brain pathology in regard to cognitive impairment: the effect of education seems most pronounced in early disease stages but may ultimately be overwhelmed by the pathological changes. The results extend the concept of CR to VCI.},
	number = {2},
	journal = {Neurobiol Aging},
	author = {Zieren, N. and Duering, M. and Peters, N. and Reyes, S. and Jouvent, E. and Herve, D. and Gschwendtner, A. and Mewald, Y. and Opherk, C. and Chabriat, H. and Dichgans, M.},
	month = feb,
	year = {2013},
	pmid = {22626524},
	keywords = {Cognition, Adult, Aged, Female, Humans, Male, Middle Aged, Prospective Studies, Magnetic Resonance Imaging, Brain/*pathology/physiopathology, *Cognitive Reserve, CADASIL/*pathology/physiopathology/psychology, Educational Status, Executive Function, Memory, Neuropsychological Tests, Brain, CADASIL, Cognitive Reserve},
	pages = {400--7},
}

@article{ radua_new_2012,
  title = {A new meta-analytic method for neuroimaging studies that combines reported peak coordinates and statistical parametric maps},
  volume = {27},
  issn = {1778-3585},
  doi = {10.1016/j.eurpsy.2011.04.001},
  abstract = {Meta-analyses are essential to summarize the results of the growing number of neuroimaging studies in psychiatry, neurology and allied disciplines. Image-based meta-analyses use full image information (i.e. the statistical parametric maps) and well-established statistics, but images are rarely available making them highly unfeasible. Peak-probability meta-analyses such as activation likelihood estimation (ALE) or multilevel kernel density analysis (MKDA) are more feasible as they only need reported peak coordinates. Signed-differences methods, such as signed differential mapping (SDM) build upon the positive features of existing peak-probability methods and enable meta-analyses of studies comparing patients with controls. In this paper we present a new version of SDM, named Effect Size SDM (ES-SDM), which enables the combination of statistical parametric maps and peak coordinates and uses well-established statistics. We validated the new method by comparing the results of an ES-SDM meta-analysis of studies on the brain response to fearful faces with the results of a pooled analysis of the original individual data. The results showed that ES-SDM is a valid and reliable coordinate-based method, whose performance might be additionally increased by including statistical parametric maps. We anticipate that ES-SDM will be a helpful tool for researchers in the fields of psychiatry, neurology and allied disciplines.},
  language = {eng},
  number = {8},
  journal = {European Psychiatry: The Journal of the Association of European Psychiatrists},
  author = {Radua, J. and Mataix-Cols, D. and Phillips, M. L. and El-Hage, W. and Kronhaus, D. M. and Cardoner, N. and Surguladze, S.},
  month = {November},
  year = {2012},
  pmid = {21658917},
  keywords = {Adult, Brain, Brain Mapping, Facial Expression, Humans, Magnetic Resonance Imaging, Neuroimaging, Neuropsychological Tests, Reproducibility of Results},
  pages = {605--611}
}

@article{baracos_advances_2012,
	title = {Advances in the science and application of body composition measurement},
	volume = {36},
	issn = {1941-2444},
	doi = {10.1177/0148607111417448},
	language = {eng},
	number = {1},
	journal = {JPEN. Journal of parenteral and enteral nutrition},
	author = {Baracos, Vickie and Caserotti, Paolo and Earthman, Carrie P. and Fields, David and Gallagher, Dympna and Hall, Kevin D. and Heymsfield, Steven B. and Müller, Manfred J. and Rosen, Antonella Napolitano and Pichard, Claude and Redman, Leanne M. and Shen, Wei and Shepherd, John A. and Thomas, Diana},
	month = jan,
	year = {2012},
	pmid = {22235108},
	pmcid = {PMC4422066},
	keywords = {Absorptiometry, Photon, Acute Disease, Adipose Tissue, Aging, Body Composition, Chronic Disease, Dielectric Spectroscopy, Energy Metabolism, Humans, Magnetic Resonance Imaging, Metabolic Diseases, Models, Biological, Neoplasms},
	pages = {96--107}
}

Paper  doi  abstract   bibtex   

@article{hayashi_knee_2012,
	title = {Knee malalignment is associated with an increased risk for incident and enlarging bone marrow lesions in the more loaded compartments: {The} {MOST} study.},
	volume = {20},
	issn = {1522-9653},
	shorttitle = {Knee malalignment is associated with an increased risk for incident and enlarging bone marrow lesions in the more loaded compartments},
	url = {http://dx.doi.org/10.1016%2Fj.joca.2012.07.020},
	doi = {10.1016/j.joca.2012.07.020},
	abstract = {OBJECTIVE: To examine the relationship of knee malalignment with occurrence of incident and enlarging bone marrow lesions (BMLs) and regression of BMLs.
METHODS: Subjects from the Multicenter Osteoarthritis Study aged 50-79 years with or at high risk of knee osteoarthritis were studied. Full-limb radiographs were taken at baseline and hip-knee-ankle mechanical axis was measured. Baseline and 30-month magnetic resonance imaging (MRI) of knees (n = 1782) were semiquantitatively assessed for BMLs. Outcome was defined as a change in BML score in femoral/tibial condyle in medial/lateral compartments. Medial compartment in varus alignment and lateral compartment in valgus alignment were combined to form 'more loaded' compartment, while lateral compartment in valgus and medial compartment in varus were combined to form 'less loaded' compartment. Relative risk (RR) of BML score increase or decrease in relation to malalignment was estimated using a log linear regression model with the Poisson assumption, adjusting for age, gender, body mass index, physical activity scale for the elderly, race and clinic site. Further, results were stratified by ipsilateral meniscal and cartilage status at baseline.
RESULTS: Baseline varus alignment was associated with higher risk of BML score increase from baseline to follow-up in the medial compartment [adjusted RRs (95\%CI): 1.5 (1.2-1.9)] and valgus alignment in the lateral compartment [1.4 (1.0-2.1)]. Increase in BML score was more likely in the more loaded compartments [1.7 (1.4-2.0)] in malaligned knees. Regardless of ipsilateral cartilage or meniscus status, adjusted RR for BML score increase was higher in the more loaded compartments of malaligned knees than those with neutral alignment. Decrease in BML score was less likely in the more loaded compartments in malaligned knees [0.8 (0.7-1.0)].
CONCLUSION: Knee malalignment is associated with increased risk of incident and enlarging BMLs in the more loaded compartments of the tibiofemoral joint.},
	language = {eng},
	number = {11},
	journal = {Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society},
	author = {Hayashi, D. and Englund, M. and Roemer, F. W. and Niu, J. and Sharma, L. and Felson, D. T. and Crema, M. D. and Marra, M. D. and Segal, N. A. and Lewis, C. E. and Nevitt, M. C. and Guermazi, A.},
	month = nov,
	year = {2012},
	pmid = {22874524},
	pmcid = {PMC3448813},
	keywords = {Aged, Bone Malalignment, Bone Marrow, Bone Marrow Diseases, Cartilage, Articular, Coxa Valga, Coxa Vara, Female, Humans, Knee Joint, Magnetic resonance imaging, Male, Menisci, Tibial, Middle Aged, Osteoarthritis, Knee, Risk Factors},
	pages = {1227--1233},
}

Paper  abstract   bibtex   

@article{
 title = {Joint tumor segmentation and dense deformable registration of brain MR images.},
 type = {article},
 year = {2012},
 keywords = {Algorithms,Automated,Automated: methods,Brain,Brain Neoplasms,Brain Neoplasms: pathology,Brain: pathology,Computer-Assisted,Computer-Assisted: methods,Humans,Image Enhancement,Image Enhancement: methods,Image Interpretation,Magnetic Resonance Imaging,Magnetic Resonance Imaging: methods,Pattern Recognition,Reproducibility of Results,Sensitivity and Specificity,Subtraction Technique},
 pages = {651-8},
 volume = {15},
 websites = {http://www.ncbi.nlm.nih.gov/pubmed/23286104},
 id = {1c3dd5ae-9af5-3dfe-b9d4-a950eb79cb77},
 created = {2015-09-08T00:08:17.000Z},
 file_attached = {true},
 profile_id = {c08cee0c-cdfe-3253-a183-89b4a1ce8187},
 last_modified = {2015-09-08T00:15:37.000Z},
 read = {false},
 starred = {false},
 authored = {true},
 confirmed = {true},
 hidden = {false},
 abstract = {In this paper we propose a novel graph-based concurrent registration and segmentation framework. Registration is modeled with a pairwise graphical model formulation that is modular with respect to the data and regularization term. Segmentation is addressed by adopting a similar graphical model, using image-based classification techniques while producing a smooth solution. The two problems are coupled via a relaxation of the registration criterion in the presence of tumors as well as a segmentation through a registration term aiming the separation between healthy and diseased tissues. Efficient linear programming is used to solve both problems simultaneously. State of the art results demonstrate the potential of our method on a large and challenging low-grade glioma data set.},
 bibtype = {article},
 author = {Parisot, Sarah and Duffau, Hugues and Chemouny, Stéphane and Paragios, Nikos},
 journal = {Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention},
 number = {Pt 2}
}

@article{yao_nihss_2012,
	title = {{NIHSS} scores in ischemic small vessel disease: a study in {CADASIL}},
	volume = {34},
	issn = {1421-9786 (Electronic) 1015-9770 (Linking)},
	doi = {10.1159/000345067},
	abstract = {BACKGROUND: The National Institutes of Health Stroke Scale (NIHSS) is widely used to measure neurological deficits, evaluate the effectiveness of treatment and predict outcome in acute ischemic stroke. It has also been used to measure the residual neurological deficit at the chronic stage after ischemic events. However, the value of NIHSS in ischemic cerebral small vessel disease has not been specifically evaluated. The purpose of this study was to investigate the link between the NIHSS score and clinical severity in a large population of subjects with CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy), a unique model to investigate the pathophysiology and natural history of ischemic small vessel disease. METHODS: Demographic and clinical data of 220 patients with one or more lacunar infarcts confirmed by MRI examination and enrolled from a prospective cohort study were analyzed. Detailed neurological examinations, including evaluation of the NIHSS and modified Rankin Scale score (mRS) for evaluating the clinical severity, were performed in all subjects. The sensitivity, specificity, positive and negative predictive values of various NIHSS thresholds to capture the absence of significant disability (mRS {\textless}3) were calculated. General linear models, controlling for age, educational level and different clinical manifestations frequently observed in CADASIL, were used to evaluate the relationships between NIHSS and clinical severity. RESULTS: In the whole cohort, 45 (20.5\%) subjects presented with mRS {\textgreater}/=3, but only 16 (7.3\%) had NIHSS {\textgreater}5. All but 1 subject with NIHSS {\textgreater}5 showed mRS {\textgreater}/=3. NIHSS {\textless}/=5 had an 85.3\% positive predictive value for no or slight disability with only 33.3\% specificity. The NIHSS, MMSE score and presence or absence of gait disturbances were found to be strongly and independently correlated with disability (all p {\textless} 0.001). Altogether, they accounted for 73\% of the variance of mRS in contrast with the NIHSS alone accounting for only 50\% of this variance. Among patients with NIHSS {\textless}/=5, subjects with mRS {\textgreater}/=3 showed a lower MMSE score than those with mRS {\textless}3 (p {\textless} 0.001). All patients with NIHSS {\textless}/=5 but with mRS {\textgreater}/=3 presented either with gait disturbances or MMSE score {\textless}25. CONCLUSIONS: The present results suggest that the NIHSS cannot reflect the extent of neurological deficit and clinical severity in subjects with lacunar infarctions in the context of a chronic and diffuse small vessel disease. A specific and global neurological scale, including the assessment of cognitive and gait performances, should be developed for ischemic cerebral microangiopathy.},
	number = {5-6},
	journal = {Cerebrovasc Dis},
	author = {Yao, M. and Herve, D. and Allili, N. and Jouvent, E. and Duering, M. and Dichgans, M. and Chabriat, H.},
	year = {2012},
	pmid = {23221354},
	keywords = {Adult, Aged, Disease Progression, Female, Humans, Male, Middle Aged, Prospective Studies, Magnetic Resonance Imaging, Cohort Studies, Neuropsychological Tests, Magnetic Resonance Imaging/methods, Sensitivity and Specificity, Severity of Illness Index, CADASIL/*diagnosis, Brain Ischemia/*diagnosis, Cerebral Small Vessel Diseases/*diagnosis, National Institutes of Health (U.S.), United States, Cerebral Small Vessel Diseases, CADASIL, Brain Ischemia},
	pages = {419--23},
}

Paper  doi  abstract   bibtex   

@article{luchinger_eegbold_2011,
	title = {{EEG}–{BOLD} correlations during (post-) adolescent brain maturation},
	volume = {56},
	issn = {10538119},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/21349336},
	doi = {10.1016/j.neuroimage.2011.02.050},
	abstract = {The transition from adolescence to adulthood is a critical stage in the human lifespan during which the brain still undergoes substantial structural and functional change. The changing frequency composition of the resting state EEG reflects maturation of brain function. This study investigated (post)adolescent brain maturation captured by two independently but simultaneously recorded neuronal signals: EEG and fMRI. Data were collected in a 20 min eyes-open/eyes-closed resting state paradigm. EEG, fMRI-BOLD signal and EEG-BOLD correlations were compared between groups of adults, age 25 (n=18), and adolescents, age 15 (n=18). A typical developmental decrease of low-frequency EEG power was observed even at this late stage of brain maturation. Frequency and condition specific EEG-fMRI correlations proved robust for multiple brain regions. However, no consistent change in the EEG-BOLD correlations was identified that would correspond to the neuronal maturation captured by the EEG. This result indicates that the EEG-BOLD correlation measures a distinct aspect of neurophysiological activity that presumably matures earlier, since it is less sensitive to late maturation than the neuronal activity captured by low-frequency EEG.},
	number = {3},
	urldate = {2015-04-10},
	journal = {NeuroImage},
	author = {Lüchinger, Rafael and Michels, Lars and Martin, Ernst and Brandeis, Daniel},
	month = jun,
	year = {2011},
	pmid = {21349336},
	keywords = {Adolescent, Adult, Aging, Aging: physiology, Alpha Rhythm, Alpha Rhythm: physiology, Brain, Brain: growth \& development, Data Interpretation, Delta Rhythm, Delta Rhythm: physiology, Electroencephalography, Female, Humans, Magnetic Resonance Imaging, Male, Models, Nerve Net, Nerve Net: growth \& development, Nerve Net: physiology, Neurological, Oxygen, Oxygen: blood, Photic Stimulation, Regression Analysis, Rest, Rest: physiology, Statistical, Theta Rhythm, Theta Rhythm: physiology, Young Adult},
	pages = {1493--1505},
}

Paper  doi  abstract   bibtex   

@article{mulligan_neural_2011,
	title = {Neural correlates of inhibitory control in adult attention deficit/hyperactivity disorder: evidence from the {Milwaukee} longitudinal sample.},
	volume = {194},
	issn = {0165-1781},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/21937201},
	doi = {10.1016/j.pscychresns.2011.02.003},
	abstract = {Only a few studies have investigated the neural substrate of response inhibition in adult attention deficit hyperactivity disorder (ADHD) using Stop-Signal and Go/No-Go tasks. Inconsistencies and methodological limitations in the existing literature have resulted in limited conclusions regarding underlying pathophysiology. We examined the neural basis of response inhibition in a group of adults diagnosed with ADHD in childhood and who continue to meet criteria for ADHD. Adults with ADHD (n=12) and controls (n=12) were recruited from an ongoing longitudinal study and were matched for age, IQ, and education. Individuals with comorbid conditions were excluded. Functional magnetic resonance imaging (fMRI) was used to identify and compare the brain activation patterns during correct trials of a response-inhibition task (Go/No-Go). Our results showed that the control group recruited a more extensive network of brain regions than the ADHD group during correct inhibition trials. Adults with ADHD showed reduced brain activation in the right frontal eye field, pre-supplementary motor area, left precentral gyrus, and the inferior parietal lobe bilaterally. During successful inhibition of an inappropriate response, adults with ADHD display reduced activation in fronto-parietal networks previously implicated in working memory, goal-oriented attention, and response selection. This profile of brain activation may be specifically associated with ADHD in adulthood.},
	number = {2},
	urldate = {2012-03-22},
	journal = {Psychiatry research},
	author = {Mulligan, Richard C and Knopik, Valerie S and Sweet, Lawrence H and Fischer, Mariellen and Seidenberg, Michael and Rao, Stephen M},
	month = nov,
	year = {2011},
	pmid = {21937201},
	keywords = {Adult, Attention Deficit Disorder with Hyperactivity, Attention Deficit Disorder with Hyperactivity: com, Attention Deficit Disorder with Hyperactivity: psy, Brain, Brain Mapping, Brain: blood supply, Brain: physiopathology, Cognition Disorders, Cognition Disorders: etiology, Cognition Disorders: pathology, Decision Making, Decision Making: physiology, Female, Humans, Image Processing, Computer-Assisted, Inhibition (Psychology), Intelligence, Longitudinal Studies, Magnetic Resonance Imaging, Magnetic Resonance Imaging: methods, Male, Neuropsychological Tests, Oxygen, Oxygen: blood, Wisconsin, Wisconsin: epidemiology},
	pages = {119--29},
}

@article{kolnagou_efficacy_2011,
	title = {Efficacy, compliance and toxicity factors are affecting the rate of normalization of body iron stores in thalassemia patients using the deferiprone and  deferoxamine combination therapy.},
	volume = {35},
	issn = {1532-432X 0363-0269},
	doi = {10.3109/03630269.2011.576153},
	language = {eng},
	number = {3},
	journal = {Hemoglobin},
	author = {Kolnagou, Annita and Kleanthous, Marios and Kontoghiorghes, George J.},
	year = {2011},
	pmid = {21599431},
	note = {Place: England},
	keywords = {Deferiprone, Deferoxamine/*therapeutic use, Drug Therapy, Combination, Ferritins/blood/drug effects, Humans, Iron Chelating Agents/pharmacokinetics/therapeutic use/toxicity, Iron/*metabolism, Liver/metabolism, Longitudinal Studies, Magnetic Resonance Imaging, Myocardium/metabolism, Pyridones/*therapeutic use, beta-Thalassemia/*drug therapy/metabolism},
	pages = {186--198},
}

Website  abstract   bibtex   

@article{
 title = {ERPs and neural oscillations during volitional supporession of memory retrieval},
 type = {article},
 year = {2010},
 identifiers = {[object Object]},
 keywords = {Adolescent,Analysis of Variance,Association Learning,Association Learning: physiology,Biological Clocks,Biological Clocks: physiology,Brain,Brain Mapping,Brain: blood supply,Brain: physiology,Electroencephalography,Emotions,Emotions: physiology,Evoked Potentials,Evoked Potentials: physiology,Female,Humans,Image Processing, Computer-Assisted,Magnetic Resonance Imaging,Male,Mental Recall,Mental Recall: physiology,Oxygen,Oxygen: blood,Photic Stimulation,Reaction Time,Visual Perception,Young Adult},
 pages = {1-10},
 volume = {25},
 websites = {http://www.mitpressjournals.org/doi/abs/10.1162/jocn_a_00418#.Vgcwxo9Viko},
 month = {10},
 publisher = {MIT Press55 Hayward Street, Cambridge, MA 02142-1315USAjournals-info@mit.edu},
 day = {28},
 id = {9e3549f7-2c0d-33e4-84d8-bab5eb144557},
 created = {2015-09-27T00:17:34.000Z},
 accessed = {2015-09-26},
 file_attached = {false},
 profile_id = {50a856f4-e41b-3395-a32c-35f3a97eb9f9},
 group_id = {1d7f53de-0a60-3d99-b9ab-c9b479ac932e},
 last_modified = {2015-11-28T00:03:58.000Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 citation_key = {Depue2010m},
 language = {en},
 abstract = {Although investigations of memory and the dynamics of ERP components and neural oscillations as assessed through EEG have been well utilized, little research into the volitional nature of suppression over memory retrieval have used these methods. Oscillation analyses conducted on the Think/No-Think (TNT) task and volitional suppression of retrieval are of interest to broaden our knowledge of neural oscillations associated not only during successful memory retrieval but also when retrieval is unwanted or suppressed. In the current study, we measured EEG during a TNT task and performed ERP and EEG spectral power band analyses. ERP results replicated other researchers' observations of increases in 500-800 msec parietal effects for items where retrieval was instructed to be elaborated compared with being suppressed. Furthermore, EEG analyses indicated increased alpha (8-12 Hz) and theta (3-8 Hz) oscillations across parietal electrodes for items that were instructed to be suppressed versus those to be elaborated. Additionally, during the second half of the experiment (after repeated attempts at control), increases in theta oscillations were found across both frontal and parietal electrodes for items that were instructed to be suppressed and that were ultimately forgotten versus those ultimately remembered. Increased alpha power for items that were instructed to be suppressed versus elaborated may indicate reductions of retrieval attempts or lack of retrieval success. Increased theta power for items that were instructed to be suppressed versus elaborated may indicate increased or prolonged cognitive control to monitor retrieval events.},
 bibtype = {article},
 author = {Depue, Brendan Eliot and Ketz, Nick and Mollison, Matthew V and Nyhus, Erika and Banich, Marie T and Curran, Tim},
 journal = {Journal of Cognitive Neuroscience},
 number = {10}
}

Paper  abstract   bibtex   

@article{
 title = {Dissemination limits the survival of patients with anaplastic ependymoma after extensive surgical resection, meticulous follow up, and intensive treatment for recurrence.},
 type = {article},
 year = {2010},
 identifiers = {[object Object]},
 keywords = {Adjuvant,Adolescent,Adult,Brain Neoplasms,Brain Neoplasms: diagnosis,Brain Neoplasms: mortality,Brain Neoplasms: pathology,Brain Neoplasms: therapy,Chemotherapy,Child,Ependymoma,Ependymoma: diagnosis,Ependymoma: mortality,Ependymoma: pathology,Ependymoma: therapy,Female,Follow-Up Studies,Humans,Kaplan-Meier Estimate,Local,Local: therapy,Magnetic Resonance Imaging,Male,Middle Aged,Neoplasm Recurrence,Preschool,Radiotherapy,Retrospective Studies,Survival Rate},
 pages = {185-91; discussion 191-2},
 volume = {33},
 websites = {http://www.ncbi.nlm.nih.gov/pubmed/20186454},
 month = {4},
 id = {095ad00f-60e1-3a2f-8cae-2eb3aba8490a},
 created = {2013-09-07T05:22:53.000Z},
 accessed = {2013-09-07},
 file_attached = {true},
 profile_id = {8c4ca2d5-86de-3b5d-86be-8408415f34e0},
 group_id = {a484ae4c-fcac-3c7e-9ac3-3fad0df719a2},
 last_modified = {2014-11-22T16:36:56.000Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 abstract = {The extent of resection is the most consistent factor affecting outcome of intracranial ependymomas. The outcomes in patients with intracranial anaplastic ependymomas who underwent more than subtotal resection and intensive treatment for recurrence were reviewed retrospectively. Between 1989 and 2007, 18 patients underwent more than subtotal resection at Tohoku University Hospital. Adjuvant chemoradiation therapy was conducted in 16 patients. Meticulous follow-up was performed for early detection of recurrence. Intensive therapy including surgery and chemoradiation therapy was added for recurrence. Median survival in all 18 patients was 136 months. The 5- and 10-year survival rates were 59.1% and 50.7%, respectively. Eight patients died during the observation period, five of dissemination, but none of uncontrollable local recurrence. High resection rate, meticulous follow-up, and intensive treatment for recurrence improved the survival of patients with anaplastic ependymoma. Dissemination was the life-determining factor in this series of patients.},
 bibtype = {article},
 author = {Saito, Ryuta and Kumabe, Toshihiro and Kanamori, Masayuki and Sonoda, Yukihiko and Tominaga, Teiji},
 journal = {Neurosurgical Review},
 number = {2}
}

Paper  abstract   bibtex   

@article{holzel_stress_2010,
	title = {Stress reduction correlates with structural changes in the amygdala},
	volume = {5},
	issn = {["1749-5024", "1749-5016"]},
	url = {https://www.ncbi.nlm.nih.gov/pubmed/19776221},
	abstract = {Stress has significant adverse effects on health and is a risk factor for many illnesses. Neurobiological studies have implicated the amygdala as a brain structure crucial in stress responses. Whereas hyperactive amygdala function is often observed during stress conditions, cross-sectional reports of differences in gray matter structure have been less consistent. We conducted a longitudinal MRI study to investigate the relationship between changes in perceived stress with changes in amygdala gray matter density following a stress-reduction intervention. Stressed but otherwise healthy individuals (N = 26) participated in an 8-week mindfulness-based stress reduction intervention. Perceived stress was rated on the perceived stress scale (PSS) and anatomical MR images were acquired pre- and post-intervention. PSS change was used as the predictive regressor for changes in gray matter density within the bilateral amygdalae. Following the intervention, participants reported significantly reduced perceived stress. Reductions in perceived stress correlated positively with decreases in right basolateral amygdala gray matter density. Whereas prior studies found gray matter modifications resulting from acquisition of abstract information, motor and language skills, this study demonstrates that neuroplastic changes are associated with improvements in a psychological state variable.},
	language = {eng},
	number = {1},
	urldate = {0003-01-01},
	journal = {Social cognitive and affective neuroscience},
	author = {Hölzel, Britta K and Carmody, James and Evans, Karleyton C and Hoge, Elizabeth A and Dusek, Jeffery A and Morgan, Lucas and Pitman, Roger K and Lazar, Sara W},
	year = {2010},
	keywords = {Adult, Amygdala, Amygdala/*pathology, Brain Mapping, Female, Humans, Magnetic Resonance Imaging, Male, Meditation, Psychiatric Status Rating Scales, Psychotherapy, Group, Stress, Psychological/*pathology/*therapy, Treatment Outcome, Yoga},
	pages = {11--17},
}

Website  abstract   bibtex   

@article{
 title = {An fMRI study of parietal cortex involvement in the visual guidance of locomotion.},
 type = {article},
 year = {2010},
 identifiers = {[object Object]},
 keywords = {Adult,Brain Mapping,Cues,Distance Perception,Distance Perception: physiology,Dominance, Cerebral,Dominance, Cerebral: physiology,Female,Fixation, Ocular,Fixation, Ocular: physiology,Humans,Image Processing, Computer-Assisted,Kinesthesis,Kinesthesis: physiology,Locomotion,Locomotion: physiology,Magnetic Resonance Imaging,Male,Nerve Net,Nerve Net: physiology,Optic Flow,Optic Flow: physiology,Orientation,Orientation: physiology,Oxygen Consumption,Oxygen Consumption: physiology,Parietal Lobe,Parietal Lobe: physiology,Psychomotor Performance,Psychomotor Performance: physiology,Saccades,Saccades: physiology,Visual Perception,Visual Perception: physiology,Young Adult},
 pages = {1495-507},
 volume = {36},
 websites = {http://psycnet.apa.org/journals/xhp/36/6/1495.html},
 month = {12},
 publisher = {American Psychological Association},
 day = {1},
 id = {d6e8443d-ed66-3783-81b3-3c281afdea75},
 created = {2016-01-20T16:02:53.000Z},
 accessed = {2015-12-10},
 file_attached = {false},
 profile_id = {d5b53108-91c5-30b8-8e6c-dd027f636bcd},
 last_modified = {2016-01-21T12:29:57.000Z},
 read = {false},
 starred = {false},
 authored = {true},
 confirmed = {true},
 hidden = {false},
 language = {English},
 abstract = {Locomoting through the environment typically involves anticipating impending changes in heading trajectory in addition to maintaining the current direction of travel. We explored the neural systems involved in the "far road" and "near road" mechanisms proposed by Land and Horwood (1995) using simulated forward or backward travel where participants were required to gauge their current direction of travel (rather than directly control it). During forward egomotion, the distant road edges provided future path information, which participants used to improve their heading judgments. During backward egomotion, the road edges did not enhance performance because they no longer provided prospective information. This behavioral dissociation was reflected at the neural level, where only simulated forward travel increased activation in a region of the superior parietal lobe and the medial intraparietal sulcus. Providing only near road information during a forward heading judgment task resulted in activation in the motion complex. We propose a complementary role for the posterior parietal cortex and motion complex in detecting future path information and maintaining current lane positioning, respectively.},
 bibtype = {article},
 author = {Billington, Jac and Field, David T and Wilkie, Richard M and Wann, John P},
 journal = {Journal of experimental psychology. Human perception and performance},
 number = {6}
}

Paper  doi  abstract   bibtex   

@article{ongur_default_2010,
	title = {Default mode network abnormalities in bipolar disorder and schizophrenia.},
	volume = {183},
	issn = {0165-1781},
	url = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2902695&tool=pmcentrez&rendertype=abstract},
	doi = {10.1016/j.pscychresns.2010.04.008},
	abstract = {The default-mode network (DMN) consists of a set of brain areas preferentially activated during internally focused tasks. We used functional magnetic resonance imaging (fMRI) to study the DMN in bipolar mania and acute schizophrenia. Participants comprised 17 patients with bipolar disorder (BD), 14 patients with schizophrenia (SZ) and 15 normal controls (NC), who underwent 10-min resting fMRI scans. The DMN was extracted using independent component analysis and template-matching; spatial extent and timecourse were examined. Both patient groups showed reduced DMN connectivity in the medial prefrontal cortex (mPFC) (BD: x=-2, y=54, z=-12; SZ: x=-2, y=22, z=18). BD subjects showed abnormal recruitment of parietal cortex (correlated with mania severity) while SZ subjects showed greater recruitment of the frontopolar cortex/basal ganglia. Both groups had significantly higher frequency fluctuations than controls. We found ventral mPFC abnormalities in BD and dorsal mPFC abnormalities in SZ. The higher frequency of BOLD signal oscillations observed in patients suggests abnormal functional organization of circuits in both disorders. Further studies are needed to determine how these abnormalities are related to specific symptoms of each condition.},
	number = {1},
	urldate = {2015-03-02},
	journal = {Psychiatry research},
	author = {Ongür, Dost and Lundy, Miriam and Greenhouse, Ian and Shinn, Ann K and Menon, Vinod and Cohen, Bruce M and Renshaw, Perry F},
	month = jul,
	year = {2010},
	pmid = {20553873},
	keywords = {Adult, Bipolar Disorder, Bipolar Disorder: pathology, Brain, Brain Mapping, Brain: blood supply, Brain: pathology, Female, Functional Laterality, Humans, Image Processing, Computer-Assisted, Image Processing, Computer-Assisted: methods, Magnetic Resonance Imaging, Magnetic Resonance Imaging: methods, Male, Middle Aged, Models, Neurological, Nerve Net, Nerve Net: blood supply, Schizophrenia, Schizophrenia: pathology, Spectrum Analysis, Young Adult},
	pages = {59--68},
}

@article{
 title = {Imaging of ependymomas: MRI and CT.},
 type = {article},
 year = {2009},
 identifiers = {[object Object]},
 keywords = {Brain Neoplasms,Brain Neoplasms: metabolism,Brain Neoplasms: pathology,Brain Neoplasms: radiography,Child, Preschool,Diffusion Magnetic Resonance Imaging,Ependymoma,Ependymoma: metabolism,Ependymoma: pathology,Ependymoma: radiography,Humans,Magnetic Resonance Imaging,Magnetic Resonance Spectroscopy,Perfusion Imaging,Protons,Spinal Cord Neoplasms,Spinal Cord Neoplasms: metabolism,Spinal Cord Neoplasms: pathology,Spinal Cord Neoplasms: radiography,Tomography, X-Ray Computed},
 pages = {1203-13},
 volume = {25},
 websites = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2744772&tool=pmcentrez&rendertype=abstract},
 month = {10},
 id = {2861e18e-9fb0-3054-889f-dab7b8dba29b},
 created = {2015-04-16T16:43:58.000Z},
 accessed = {2015-04-16},
 file_attached = {false},
 profile_id = {77af58c9-50fe-33a7-884e-41c4f0059fcb},
 group_id = {a484ae4c-fcac-3c7e-9ac3-3fad0df719a2},
 last_modified = {2015-04-16T16:43:58.000Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 abstract = {The imaging features of intracranial and spinal ependymoma are reviewed with an emphasis on conventional magnetic resonance imaging (MRI), perfusion MRI and proton magnetic resonance spectroscopy, and computed tomography. Imaging manifestations of leptomeningeal dissemination of disease are described. Finally, salient imaging features obtained in the postoperative period to evaluate completeness of surgical resection, and thereafter for long-term surveillance for disease recurrence, are reviewed.},
 bibtype = {article},
 author = {Yuh, E L and Barkovich, A J and Gupta, N},
 journal = {Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery},
 number = {10}
}

@article{freiwald_face_2009,
	title = {A face feature space in the macaque temporal lobe.},
	volume = {12},
	doi = {10.1038/nn.2363},
	abstract = {The ability of primates to effortlessly recognize faces has been attributed to the existence of specialized face areas. One such area, the macaque middle face patch, consists almost entirely of cells that are selective for faces, but the principles by which these cells analyze faces are unknown. We found that middle face patch neurons detect and differentiate faces using a strategy that is both part based and holistic. Cells detected distinct constellations of face parts. Furthermore, cells were tuned to the geometry of facial features. Tuning was most often ramp-shaped, with a one-to-one mapping of feature magnitude to firing rate. Tuning amplitude depended on the presence of a whole, upright face and features were interpreted according to their position in a whole, upright face. Thus, cells in the middle face patch encode axes of a face space specialized for whole, upright faces},
	language = {eng},
	number = {9},
	journal = {Nat Neurosci},
	author = {Freiwald, Winrich A and Tsao, Doris Y and Livingstone, Margaret S},
	year = {2009},
	pmid = {19668199},
	note = {Place: United States
ISBN: 1546-1726},
	keywords = {Action Potentials, Analysis of Variance, Animals, Face, Macaca mulatta, Magnetic Resonance Imaging, Male, Microelectrodes, Neurons, Photic Stimulation, Temporal Lobe, Time Factors, Visual Perception, research support, n.i.h., extramural, research support, non-u.s. gov't},
	pages = {1187--1196},
}

Paper  doi  abstract   bibtex   

@article{frye_increased_2009,
	title = {Increased prefrontal activation in adolescents born prematurely at high risk during a reading task.},
	volume = {1303},
	issn = {1872-6240},
	url = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2783693&tool=pmcentrez&rendertype=abstract},
	doi = {10.1016/j.brainres.2009.09.091},
	abstract = {Although individuals born prematurely have subtle white matter abnormalities and are at risk for cognitive dysfunction, few studies have examined functional reorganization in these individuals. In this study we use magnetoencephalography (MEG) to examine cortical reorganization related to prematurity. Thirty-one adolescents systemically selected from a longitudinal study on child development based on gestational age, birth weight and neonatal complications (full term, low-risk premature, high-risk premature) and reading ability (good, average or poor) performed two reading-based rhyme tasks during MEG recording. Equivalent current dipoles were localized every 4 ms during the 150 ms to 550 ms period following the onset of the word presentation. The association of the mean number of dipole (NOD) with birth risk, reading ability and latency was examined. During the real-word rhyme task, adolescents born at high-risk demonstrated a greater NOD in the left prefrontal area than those born at low-risk and term. During the non-word rhyme task, good and average readers born at high-risk demonstrated a greater NOD in the left prefrontal area than good and average readers born at low-risk and term. Time course analysis confirmed increased activation in the left prefrontal regions of those born at high-risk. This study suggests that adolescents born prematurely at high-risk, as compared to those born at low-risk and term, demonstrate increased prefrontal cortical activation during a reading task. These results suggest a reorganization of the prefrontal cortex in adolescents born prematurely at high-risk.},
	urldate = {2015-06-01},
	journal = {Brain research},
	author = {Frye, Richard E and Malmberg, Benjamin and Desouza, Laura and Swank, Paul and Smith, Karen and Landry, Susan},
	month = dec,
	year = {2009},
	pmid = {19796631},
	keywords = {Adolescent, Asphyxia Neonatorum, Asphyxia Neonatorum: complications, Asphyxia Neonatorum: physiopathology, Birth Weight, Brain Mapping, Cohort Studies, Dyslexia, Dyslexia: diagnosis, Dyslexia: etiology, Dyslexia: physiopathology, Female, Gestational Age, Humans, Hypoxia, Brain, Hypoxia, Brain: complications, Hypoxia, Brain: physiopathology, Infant, Newborn, Language Tests, Longitudinal Studies, Magnetic Resonance Imaging, Magnetoencephalography, Male, Neuronal Plasticity, Neuronal Plasticity: physiology, Prefrontal Cortex, Prefrontal Cortex: physiopathology, Pregnancy, Pregnancy, High-Risk, Pregnancy, High-Risk: physiology, Premature Birth, Premature Birth: physiopathology, Reading},
	pages = {111--9},
}

Paper  bibtex   

@article{smadja_l_GADOLINIUMENHANCED_2009,
title = {Gadolinium-enhanced thoracic CTA: retrospective analysis of image quality and tolerability in 45 patients evaluated prior to th edescription of nephrogenic systemic fibrosis},
volume = {90},
issn = {0221-0363},
url = {http://www.ncbi.nlm.nih.gov/pubmed/19421113},
Language = {French},
Journal = {J. Radiol.},
author = {{Smadja L} and {Remy-Jardin M} and {Dupuis P} and {Deken-Delannoy V} and {Devos P} and {Duhamel A} and {Laffitte JJ} and {Dequiedt P} and {Remy J}},
year = {2009},
keywords = {Adult, Aged, Aged, 80 and over, Angiography/methods*, Contrast Media*/adverse effects, Data Interpretation, Statistical, Feasibility Studies, Female, Gadolinium DTPA*/adverse effects, Humans, Kidney Failure, Chronic/complications*, Magnetic Resonance Imaging, Male, Middle Aged, Nephrogenic Fibrosing Dermopathy*, Pulmonary Artery/diagnostic imaging, Radiography, Thoracic*, Randomized Controlled Trials as Topic, Retrospective Studies, Tomography, X-Ray Computed/methods*},
pages = {287-298}
}

@article{kuo_camptocormia_2009,
	title = {Camptocormia as a presentation of generalized inflammatory myopathy},
	volume = {40},
	issn = {1097-4598},
	doi = {10.1002/mus.21403},
	abstract = {Camptocormia is an abnormal truncal flexion posture that occurs while walking or standing. It is usually caused by various hypokinetic movement disorders such as Parkinson disease and multiple system atrophy. Myopathy or motor neuron disease can also be infrequent causes of camptocormia. Paraspinous muscle biopsy usually reveals focal myositis, regardless of the etiology of camptocormia. We describe the first case of generalized inflammatory myopathy with prominent camptocormia and proximal muscle weakness. Muscle biopsy of the quadriceps confirmed the diagnosis of polymyositis, and the posture showed modest improvement in response to steroid treatment.},
	language = {eng},
	number = {6},
	journal = {Muscle \& Nerve},
	author = {Kuo, Sheng-Han and Vullaganti, Mithila and Jimenez-Shahed, Joohi and Kwan, Justin Y.},
	month = dec,
	year = {2009},
	pmid = {19750541},
	keywords = {Diagnosis, Differential, Female, Humans, Lumbar Vertebrae, Magnetic Resonance Imaging, Middle Aged, Myositis, Neuromuscular Diseases, Posture},
	pages = {1059--1063},
}

Paper  bibtex   

@Article{SCI:Seg2009a,
  author =    "N.M. Segerson and M. Daccarett and T.J. Badger and
              A. Shabaan and N. Akoum and E.N. Fish and S. Rao
              and N.S. Burgon and Y. Adjei-Poku and E.G.
              Kholmovski and S. Vijayakumar and E.V.R. Dibella
              and R.S. Macleod and N.F. Marrouche",
  title =     "Magnetic Resonance Imaging-Confirmed Ablative
              Debulking of the Left Atrial Posterior Wall and
              Septum for Treatment of Persistent Atrial
              Fibrillation: Rationale and Initial Experience",
  journal =   "Journal of Cardiovascular Electrophysiology",
  volume =    "21",
  number =    "2",
  pages =     "126--132",
  year =      "2009",
  keywords =  "atrial fibrillation, radiofrequency ablation,
              debulking, magnetic resonance imaging, delayed
              enhancement, complex fractionated electrograms",
  url =       "http://www.sci.utah.edu/publications/segerson09/Segerson_JCEP2009.pdf",
}

Paper  doi  abstract   bibtex   

@article{Hadjikhani2008a,
	title = {Pointing with the eyes: the role of gaze in communicating danger.},
	volume = {68},
	issn = {1090-2147},
	url = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2582139&tool=pmcentrez&rendertype=abstract},
	doi = {10.1016/j.bandc.2008.01.008},
	abstract = {Facial expression and direction of gaze are two important sources of social information, and what message each conveys may ultimately depend on how the respective information interacts in the eye of the perceiver. Direct gaze signals an interaction with the observer but averted gaze amounts to "pointing with the eyes", and in combination with a fearful facial expression may signal the presence of environmental danger. We used fMRI to examine how gaze direction influences brain processing of facial expression of fear. The combination of fearful faces and averted gazes activated areas related to gaze shifting (STS, IPS) and fear-processing (amygdala, hypothalamus, pallidum). Additional modulation of activation was observed in motion detection areas, in premotor areas and in the somatosensory cortex, bilaterally. Our results indicate that the direction of gaze prompts a process whereby the brain combines the meaning of the facial expression with the information provided by gaze direction, and in the process computes the behavioral implications for the observer.},
	number = {1},
	urldate = {2013-08-25},
	journal = {Brain and cognition},
	author = {Hadjikhani, Nouchine and Hoge, Rick and Snyder, Josh and de Gelder, Beatrice},
	month = oct,
	year = {2008},
	pmid = {18586370},
	keywords = {\#nosource, Adult, Amygdala, Amygdala: physiology, Analysis of Variance, Brain, Brain: physiology, Cerebral Cortex, Cerebral Cortex: physiology, Dominance, Cerebral, Dominance, Cerebral: physiology, Facial Expression, Fear, Fear: physiology, Female, Fixation, Ocular, Humans, Hypothalamus, Hypothalamus: physiology, Image Processing, Computer-Assisted, Image Processing, Computer-Assisted: methods, Magnetic Resonance Imaging, Magnetic Resonance Imaging: methods, Male, Pattern Recognition, Visual, Pattern Recognition, Visual: physiology, Photic Stimulation, Photic Stimulation: methods, Social Perception, Somatosensory Cortex, Somatosensory Cortex: physiology, Visual Perception, Visual Perception: physiology, Young Adult, cognitiva, humanos},
	pages = {1--8},
}

Paper  doi  abstract   bibtex   

@article{Kerr2008,
	title = {Imaging in vivo: watching the brain in action.},
	volume = {9},
	issn = {1471-0048},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/18270513},
	doi = {10.1038/nrn2338},
	abstract = {The appeal of in vivo cellular imaging to any neuroscientist is not hard to understand: it is almost impossible to isolate individual neurons while keeping them and their complex interactions with surrounding tissue intact. These interactions lead to the complex network dynamics that underlie neural computation which, in turn, forms the basis of cognition, perception and consciousness. In vivo imaging allows the study of both form and function in reasonably intact preparations, often with subcellular spatial resolution, a time resolution of milliseconds and a purview of months. Recently, the limits of what can be achieved in vivo have been pushed into terrain that was previously only accessible in vitro, due to advances in both physical-imaging technology and the design of molecular contrast agents.},
	number = {3},
	urldate = {2013-05-21},
	journal = {Nature reviews. Neuroscience},
	author = {Kerr, Jason N D and Denk, Winfried},
	month = mar,
	year = {2008},
	pmid = {18270513},
	keywords = {Animals, Brain, Brain Mapping, Brain: cytology, Brain: physiology, Computer-Assisted, Humans, Image Processing, Magnetic Resonance Imaging, Magnetic Resonance Imaging: methods, Models, Neurological, Neurons, Neurons: physiology, Neurons: ultrastructure, optics},
	pages = {195--205},
}

@article{scholte_feedforward_2008,
	title = {Feedforward and recurrent processing in scene segmentation: electroencephalography and functional magnetic resonance imaging.},
	volume = {20},
	doi = {10.1162/jocn.2008.20142},
	abstract = {In texture segregation, an example of scene segmentation, we can discern two different processes: texture boundary detection and subsequent surface segregation [Lamme, V. A. F., Rodriguez-Rodriguez, V., \& Spekreijse, H. Separate processing dynamics for texture elements, boundaries and surfaces in primary visual cortex of the macaque monkey. Cerebral Cortex, 9, 406-413, 1999]. Neural correlates of texture boundary detection have been found in monkey V1 [Sillito, A. M., Grieve, K. L., Jones, H. E., Cudeiro, J., \& Davis, J. Visual cortical mechanisms detecting focal orientation discontinuities. Nature, 378, 492-496, 1995; Grosof, D. H., Shapley, R. M., \& Hawken, M. J. Macaque-V1 neurons can signal illusory contours. Nature, 365, 550-552, 1993], but whether surface segregation occurs in monkey V1 [Rossi, A. F., Desimone, R., \& Ungerleider, L. G. Contextual modulation in primary visual cortex of macaques. Journal of Neuroscience, 21, 1698-1709, 2001; Lamme, V. A. F. The neurophysiology of figure ground segregation in primary visual-cortex. Journal of Neuroscience, 15, 1605-1615, 1995], and whether boundary detection or surface segregation signals can also be measured in human V1, is more controversial [Kastner, S., De Weerd, P., \& Ungerleider, L. G. Texture segregation in the human visual cortex: A functional MRI study. Journal of Neurophysiology, 83, 2453-2457, 2000]. Here we present electroencephalography (EEG) and functional magnetic resonance imaging data that have been recorded with a paradigm that makes it possible to differentiate between boundary detection and scene segmentation in humans. In this way, we were able to show with EEG that neural correlates of texture boundary detection are first present in the early visual cortex around 92 msec and then spread toward the parietal and temporal lobes. Correlates of surface segregation first appear in temporal areas (around 112 msec) and from there appear to spread to parietal, and back to occipital areas. After 208 msec, correlates of surface segregation and boundary detection also appear in more frontal areas. Blood oxygenation level-dependent magnetic resonance imaging results show correlates of boundary detection and surface segregation in all early visual areas including V1. We conclude that texture boundaries are detected in a feedforward fashion and are represented at increasing latencies in higher visual areas. Surface segregation, on the other hand, is represented in "reverse hierarchical" fashion and seems to arise from feedback signals toward early visual areas such as V1.},
	language = {eng},
	number = {11},
	journal = {J Cogn Neurosci},
	author = {Scholte, H Steven and Jolij, Jacob and Fahrenfort, Johannes J and Lamme, Victor A F},
	year = {2008},
	pmid = {18416684},
	note = {Place: United States
ISBN: 0898-929X},
	keywords = {Adolescent, Adult, Brain Mapping, Electroencephalography, Evoked Potentials, Visual, Feedback, Female, Form Perception, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Oxygen, Pattern Recognition, Visual, Photic Stimulation, Visual Cortex, Young Adult},
	pages = {2097--2109},
}

@article{
 title = {Prefrontal regions orchestrate suppression of emotional memories via a two-phase process.},
 type = {article},
 year = {2007},
 identifiers = {[object Object]},
 keywords = {Adult,Amygdala,Amygdala: physiology,Brain Mapping,Cognition,Cues,Emotions,Female,Frontal Lobe,Frontal Lobe: physiology,Hippocampus,Hippocampus: physiology,Humans,Magnetic Resonance Imaging,Male,Memory,Mental Recall,Prefrontal Cortex,Prefrontal Cortex: physiology,Pulvinar,Pulvinar: physiology,Repression, Psychology,Thinking,Visual Cortex,Visual Cortex: physiology},
 id = {e6052fbc-1b5a-343a-9182-d149433f5b27},
 created = {2016-01-05T19:45:07.000Z},
 file_attached = {false},
 profile_id = {50a856f4-e41b-3395-a32c-35f3a97eb9f9},
 group_id = {41f9b5d2-912d-3281-b756-e2d6e7ccfec5},
 last_modified = {2016-01-05T19:45:07.000Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {false},
 hidden = {false},
 abstract = {Whether memories can be suppressed has been a controversial issue in psychology and cognitive neuroscience for decades. We found evidence that emotional memories are suppressed via two time-differentiated neural mechanisms: (i) an initial suppression by the right inferior frontal gyrus over regions supporting sensory components of the memory representation (visual cortex, thalamus), followed by (ii) right medial frontal gyrus control over regions supporting multimodal and emotional components of the memory representation (hippocampus, amygdala), both of which are influenced by fronto-polar regions. These results indicate that memory suppression does occur and, at least in nonpsychiatric populations, is under the control of prefrontal regions.},
 bibtype = {article},
 author = {Depue, Brendan E and Curran, Tim and Banich, Marie T},
 journal = {Science (New York, N.Y.)}
}

@article{ hommet_atypical_2007,
  title = {Atypical neuropsychiatric symptoms revealing Hashimoto's encephalopathy},
  volume = {55},
  issn = {0002-8614},
  doi = {10.1111/j.1532-5415.2007.01219.x},
  language = {eng},
  number = {7},
  journal = {Journal of the American Geriatrics Society},
  author = {Hommet, Caroline and Mondon, Karl and Huc, Melina and Jeffredo, Sophie and Constans, Thierry and de Toffol, Bertrand and Camus, Vincent},
  month = {July},
  year = {2007},
  pmid = {17608897},
  keywords = {Aged, Brain Diseases, Diagnosis, Differential, Female, Follow-Up Studies, Glucocorticoids, Hashimoto Disease, Humans, Magnetic Resonance Imaging, Prednisolone, Psychotic Disorders},
  pages = {1144--1146}
}

Paper  abstract   bibtex   

@article{konrad_dysfunctional_2006,
	title = {Dysfunctional attentional networks in children with attention deficit/hyperactivity disorder: evidence from an event-related functional magnetic resonance imaging study.},
	volume = {59},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/16197925},
	abstract = {BACKGROUND: Although there is evidence for attentional dysfunction in children with attention deficit/hyperactivity disorder (ADHD), the neural basis of these deficits remains poorly understood. METHODS: We used event-related functional magnetic resonance imaging (fMRI) to investigate brain activations related to three particular aspects of attention: alerting, reorienting, and executive control. Sixteen medication-naive boys with ADHD and 16 healthy boys, aged 8 to 12 years, were studied. RESULTS: Behaviorally, children with ADHD showed a significant impairment only in their executive control system compared to healthy subjects. Neurally, children with ADHD (relative to controls) recruited deviant brain regions for all three attentional networks: less right-sided activation in the anterior cingulate gyrus during alerting, more fronto-striatal-insular activation during reorienting, and less fronto-striatal activation for executive control. ADHD symptom severity was associated with dysregulation of the blood oxygen level dependent (BOLD) signal within the putamen during reorienting and executive control. CONCLUSIONS: Our results demonstrated altered brain mechanism in ADHD associated with all three attentional networks investigated. For alerting and executive attention, our data indicate a deviant mechanism of cortical control, while ADHD children may have adopted altered strategies for reorienting of attention. Our results also stress the etiological role of functional abnormalities in the putamen in medication-naive ADHD.},
	number = {7},
	journal = {Biological Psychiatry},
	author = {Konrad, Kerstin and Neufang, Susanne and Hanisch, Charlotte and Fink, Gereon R and Herpertz-Dahlmann, Beate},
	year = {2006},
	pmid = {16197925},
	note = {Publisher: Department of Child and Adolescent Psychiatry, University Hospital Aachen, Germany. kkonrad@ukaachen.de},
	keywords = {attention deficit disorder with hyperactivity, attention deficit disorder with hyperactivity dia, attention deficit disorder with hyperactivity epi, attention deficit disorder with hyperactivity phy, cerebral cortex, cerebral cortex metabolism, child, cognition disorders, cognition disorders diagnosis, cognition disorders epidemiology, corpus striatum, corpus striatum metabolism, evoked potentials, evoked potentials physiology, frontal lobe, frontal lobe metabolism, gyrus cinguli, gyrus cinguli physiopathology, humans, magnetic resonance imaging, male, nerve net, nerve net physiopathology, neuropsychological tests, oxygen, oxygen blood, putamen, putamen metabolism, reaction time, reaction time physiology, severity illness index},
	pages = {643--651},
}

@article{yue_what_2006,
	title = {What makes faces special?},
	volume = {46},
	abstract = {What may be special about faces, compared to non-face objects, is that their neural representation may be fundamentally spatial, e.g., Gabor-like. Subjects matched a sequence of two filtered images, each containing every other combination of spatial frequency and orientation, of faces or non-face 3D blobs, judging whether the person or blob was the same or different. On a match trial, the images were either identical or complementary (containing the remaining spatial frequency and orientation content). Relative to an identical pair of images, a complementary pair of faces, but not blobs, reduced matching accuracy and released fMRI adaptation in the fusiform face area.},
	number = {22},
	journal = {Vision Research},
	author = {Yue, X and Tjan, B S and Biederman, I},
	year = {2006},
	pmid = {16938328},
	note = {ISBN: 0042-6989},
	keywords = {*Face, *Recognition (Psychology), Adult, Female, Humans, Judgment, Magnetic Resonance Imaging, Male, Models, Psychological, Occipital Lobe/physiology, Orientation, Pattern Recognition, Visual, Photic Stimulation/methods, Space Perception},
	pages = {3802--3811},
}

Website  abstract   bibtex   

@article{
 title = {Intact automatic avoidance of obstacles in patients with visual form agnosia.},
 type = {article},
 year = {2006},
 identifiers = {[object Object]},
 keywords = {Adult,Agnosia,Agnosia: psychology,Arm,Arm: innervation,Arm: physiology,Biomechanical Phenomena,Female,Fingers,Fingers: innervation,Fingers: physiology,Functional Laterality,Functional Laterality: physiology,Hand Strength,Humans,Magnetic Resonance Imaging,Male,Movement,Movement: physiology,Orientation,Orientation: physiology,Psychomotor Performance,Psychomotor Performance: physiology,Visual Perception,Visual Perception: physiology},
 pages = {176-88},
 volume = {174},
 websites = {http://www.ncbi.nlm.nih.gov/pubmed/16680429},
 month = {9},
 id = {1cd1441b-4d34-396b-954b-eac92b6f76fd},
 created = {2016-01-20T15:52:45.000Z},
 accessed = {2016-01-20},
 file_attached = {false},
 profile_id = {d5b53108-91c5-30b8-8e6c-dd027f636bcd},
 last_modified = {2017-03-16T06:19:45.131Z},
 read = {false},
 starred = {false},
 authored = {true},
 confirmed = {true},
 hidden = {false},
 abstract = {In everyday life our reaching behaviour has to be guided not only by the location and properties of the target object, but also by the presence of potential obstacles in the workspace. Recent evidence from neglect and optic ataxia patients has suggested that this automatic obstacle avoidance is mediated by the dorsal, rather than the ventral, stream of visual processing. We tested this idea in two studies involving patients with visual form agnosia resulting from bilateral ventral-stream damage. In the first study, we asked patient DF to reach out and pick up a target object in the presence of obstacles placed at varying distances to the left or right of the target. We found that both DF and controls shifted their trajectories away from the potential obstacles and adjusted their grip aperture in such a way as to minimize risk of collision. In a second study, we asked DF and a second patient, SB, to either reach between, or to bisect the space between, two cylinders presented at varying locations. We found that both patients adjusted their reach trajectories to account for shifts in cylinder location in the reaching task, despite showing significantly worse performance than control subjects when asked to make a bisection judgement. Taken together, these data indicate that automatic obstacle avoidance behaviour is spared in our patients with visual form agnosia. We attribute their ability to the functional intactness of the dorsal stream of visual processing, and argue that the ventral stream plays no important role in automatic obstacle avoidance.},
 bibtype = {article},
 author = {Rice, N. J. and McIntosh, R. D. and Schindler, I and Mon-Williams, M. A. and Démonet, J. F. and Milner, A. D.},
 journal = {Experimental brain research},
 number = {1}
}

@article{vogel-claussen_delayed_2006,
	title = {Delayed enhancement {MR} imaging: utility in myocardial assessment},
	volume = {26},
	issn = {1527-1323},
	shorttitle = {Delayed enhancement {MR} imaging},
	doi = {10.1148/rg.263055047},
	abstract = {Use of magnetic resonance (MR) imaging for diagnosis of cardiac diseases and treatment monitoring is expanding. Delayed myocardial enhancement MR imaging is performed after administration of paramagnetic contrast agents and is used for a growing number of clinical applications. This technique was developed primarily for characterization of myocardial scarring after myocardial infarction. On delayed enhancement MR images, scarring or fibrosis appears as an area of high signal intensity that is typically subendocardial or transmural in a coronary artery distribution. However, delayed myocardial enhancement is not specific for myocardial infarction and can occur in a variety of other disorders, such as inflammatory or infectious diseases of the myocardium, cardiomyopathy, cardiac neoplasms, and congenital or genetic cardiac conditions, as well as after cardiac interventions. In nonischemic myocardial disease, the delayed enhancement usually does not occur in a coronary artery distribution and is often midwall rather than subendocardial or transmural. Therefore, the patient's clinical history is critical in the evaluation of delayed myocardial enhancement MR images.},
	language = {eng},
	number = {3},
	journal = {Radiographics: A Review Publication of the Radiological Society of North America, Inc},
	author = {Vogel-Claussen, Jens and Rochitte, Carlos E. and Wu, Katherine C. and Kamel, Ihab R. and Foo, Thomas K. and Lima, João A. C. and Bluemke, David A.},
	month = jun,
	year = {2006},
	pmid = {16702455},
	keywords = {Cardiomyopathies, Contrast Media, Gadolinium DTPA, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Magnetic Resonance Imaging, Practice Guidelines as Topic, Practice Patterns, Physicians', Time Factors, Ventricular Dysfunction, Left},
	pages = {795--810},
}

Paper  doi  abstract   bibtex   

@article{mazard_neural_2005,
	title = {Neural impact of the semantic content of visual mental images and visual percepts},
	volume = {24},
	url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16099355},
	doi = {10/cwgtzc},
	abstract = {The existence of hemispheric lateralization of visual mental imagery remains controversial. In light of the literature, we used fMRI to test whether processing of mental images of object drawings preferentially engages the left hemisphere to compared non-object drawings. An equivalent comparison was also made while participants actually perceived object and non-object drawings. Although these two conditions engaged both hemispheres, activation was significantly stronger in the left occipito-temporo-frontal network during mental inspection of object than of non-object drawings. This network was also activated when perception of object drawings was compared to that of non-object drawings. An interaction was nonetheless observed: this effect was stronger during imagery than during perception in the left inferior frontal and the left inferior temporal gyrus. Although the tasks subjects performed did not explicitly require semantic analysis, activation of this network probably reflected, at least in part, a semantic and possibly a verbal retrieval component when object drawings were processed. Mental imagery tasks elicited activation of early visual cortex at a lower level than perception tasks. In the context of the imagery debate, these findings indicate that, as previously suggested, figurative imagery could involve primary visual cortex and adjacent areas.},
	number = {3},
	journal = {Brain Res Cogn Brain Res},
	author = {Mazard, A. and Laou, L. and Joliot, M. and Mellet, E.},
	year = {2005},
	keywords = {\#nosource, Adolescent, Adult, Cerebral Cortex/*physiology, Data Interpretation, Statistical, Female, Functional Laterality/physiology, Humans, Image Processing, Computer-Assisted, Imagination/*physiology, Learning/physiology, Magnetic Resonance Imaging, Male, Memory/*physiology, Nerve Net/physiology, Photic Stimulation, Semantics, Visual Cortex/physiology, Visual Perception/*physiology},
	pages = {423--35},
}

@article{koelsch_adults_2005,
	title = {Adults and children processing music: {An} {fMRI} study},
	volume = {25},
	issn = {10538119},
	doi = {10.1016/j.neuroimage.2004.12.050},
	abstract = {The present study investigates the functional neuroanatomy of music perception with functional magnetic resonance imaging (fMRI). Three different subject groups were investigated to examine developmental aspects and effects of musical training: 10-year-old children with varying degrees of musical training, adults without formal musical training (nonmusicians), and adult musicians. Subjects made judgements on sequences that ended on chords that were music-syntactically either regular or irregular. In adults, irregular chords activated the inferior frontal gyrus, orbital frontolateral cortex, the anterior insula, ventrolateral premotor cortex, anterior and posterior areas of the superior temporal gyrus, the superior temporal sulcus, and the supramarginal gyrus. These structures presumably form different networks mediating cognitive aspects of music processing (such as processing of musical syntax and musical meaning, as well as auditory working memory), and possibly emotional aspects of music processing. In the right hemisphere, the activation pattern of children was similar to that of adults. In the left hemisphere, adults showed larger activations than children in prefrontal areas, in the supramarginal gyrus, and in temporal areas. In both adults and children, musical training was correlated with stronger activations in the frontal operculum and the anterior portion of the superior temporal gyrus. © 2005 Elsevier Inc. All rights reserved.},
	number = {4},
	journal = {NeuroImage},
	author = {Koelsch, Stefan and Fritz, Thomas and Schulze, Katrin and Alsop, David and Schlaug, Gottfried},
	year = {2005},
	pmid = {15850725},
	note = {ISBN: 1053-8119 (Print){\textbackslash}r1053-8119 (Linking)},
	keywords = {Acoustic Stimulation, Adolescent, Adult, Aging, Auditory processing, BA 21, BA 22, BA 37, BA 44, BA 45, BA 47, BA 6, Brain, Brain Mapping, Child, Child, Preschool, Children, Female, Functional Laterality, Functional plasticity, Humans, Magnetic Resonance Imaging, Male, Music, Musical expertise, fMRI},
	pages = {1068--1076},
}

@Article{Backwell2004,
  author   = {Patricia R Y Backwell and Michael D Jennions},
  journal  = {Nature},
  title    = {Animal behaviour: {C}oalition among male fiddler crabs.},
  year     = {2004},
  number   = {6998},
  pages    = {417},
  volume   = {430},
  abstract = {Until now, no compelling evidence has emerged from studies of animal
	territoriality to indicate that a resident will strategically help
	a neighbour to defend its territory against an intruder. We show
	here that territory-owning Australian fiddler crabs will judiciously
	assist other crabs in defending their neighbouring territories. This
	cooperation supports the prediction that it is sometimes less costly
	to assist a familiar neighbour than to renegotiate boundaries with
	a new, and possibly stronger, neighbour.},
  doi      = {10.1038/430417a},
  keywords = {Animals, Attention, Brain, Decision Making, Face, Female, Haplorhini, Housing, Humans, Magnetic Resonance Imaging, Male, Models, Neurological, Pattern Recognition, Visual, Photic Stimulation, Prefrontal Cortex, Research Support, Non-U.S. Gov't, U.S. Gov't, P.H.S., Visual Perception, Choice Behavior, Cognition, Dopamine, Learning, Schizophrenia, Substance-Related Disorders, Generalization (Psychology), Motor Skills, Non-P.H.S., Nerve Net, Neuronal Plasticity, Perception, Cerebral Cortex, Memory, Neurons, Sound Localization, Synapses, Synaptic Transmission, Neural Pathways, Non-, Acoustic Stimulation, Adult, Age of Onset, Aging, Blindness, Child, Preschool, Infant, Newborn, Pitch Perception, Analysis of Variance, Animal Welfare, Laboratory, Behavior, Animal, Hybridization, Genetic, Maze Learning, Mice, Inbred C57BL, Inbred DBA, Phenotype, Reproducibility of Results, Darkness, Deafness, Finches, Sleep, Sound, Sunlight, Time Factors, Vocalization, Energy Metabolism, Evolution, Fossils, History, Ancient, Hominidae, Biological, Physical Endurance, Running, Skeleton, Walking, Acoustics, Auditory Perception, Cues, Discrimination Learning, Pair Bond, Social Behavior, Songbirds, Adolescent, England, Habituation (Psychophysiology), Korea, Language, Semantics, Vocabulary, Action Potentials, Hippocampus, Pyramidal Cells, Rats, Rotation, Australia, Brachyura, Cooperative Behavior, Logistic Models, Territoriality, 15269757},
}

Paper  doi  abstract   bibtex   

@article{baron-cohen_cognitive_2004,
	title = {The cognitive neuroscience of autism},
	volume = {75},
	copyright = {Copyright 2004 Journal of Neurology Neurosurgery and Psychiatry},
	issn = {0022-3050, 1468-330X},
	url = {https://jnnp.bmj.com/content/75/7/945},
	doi = {10.1136/jnnp.2003.018713},
	abstract = {The psychology and biology of a complex developmental condition

Autism is diagnosed when a child or adult has abnormalities in a “triad” of behavioural domains: social development, communication, and repetitive behaviour/obsessive interests.1,2 Autism can occur at any point on the IQ continuum, and IQ is a strong predictor of outcome.3 Autism is also invariably accompanied by language delay (no single words before 2 years old). Asperger syndrome (AS)4 is a subgroup on the autistic spectrum. People with AS share many of the same features as are seen in autism, but with no history of language delay and with an IQ in the average range or above. In this editorial, the main cognitive theories of autism are summarised. These are then followed by a summary of the key neurobiological findings.

The mind blindness theory of autism5 proposed that in autism spectrum conditions there are deficits in the normal process of empathy, relative to mental age. These deficits can occur by degrees. The term “empathising” encompasses a range of other terms: “theory of mind”, “mind reading”, “empathy”, and taking the “intentional stance”.6 Empathy involves two major elements: (1) the ability to attribute mental states to oneself and others, as a natural way to make sense of agents,7–9 and (2) having an emotional reaction that is appropriate to the other person’s mental state (such as sympathy).

Since the first test of mind blindness in children with autism,10 there have been more than 30 experimental tests. The vast majority of these have revealed profound impairments in the development of their empathising ability. These are reviewed elsewhere.5,11 Some children and adults with AS only show their empathising deficits on age appropriate adult tests.12–14 This deficit in their empathising is thought to underlie …},
	language = {en},
	number = {7},
	urldate = {2019-11-09},
	journal = {Journal of Neurology, Neurosurgery \& Psychiatry},
	author = {Baron-Cohen, S.},
	month = jul,
	year = {2004},
	pmid = {15201345},
	keywords = {AS, Asperger syndrome, CC, central coherence, E-S, empathising-systemising, EFT, embedded figures task, HFA, high functioning autism, MRI, magnetic resonance imaging, autism},
	pages = {945--948},
}

@Article{Abbott2004,
  author   = {LF Abbott and Wade G Regehr},
  journal  = {Nature},
  title    = {Synaptic computation.},
  year     = {2004},
  number   = {7010},
  pages    = {796-803},
  volume   = {431},
  abstract = {Neurons are often considered to be the computational engines of the
	brain, with synapses acting solely as conveyers of information. But
	the diverse types of synaptic plasticity and the range of timescales
	over which they operate suggest that synapses have a more active
	role in information processing. Long-term changes in the transmission
	properties of synapses provide a physiological substrate for learning
	and memory, whereas short-term changes support a variety of computations.
	By expressing several forms of synaptic plasticity, a single neuron
	can convey an array of different signals to the neural circuit in
	which it operates.},
  doi      = {10.1038/nature03010},
  groups   = {Gain control},
  keywords = {Animals, Attention, Brain, Decision Making, Face, Female, Haplorhini, Housing, Humans, Magnetic Resonance Imaging, Male, Models, Neurological, Pattern Recognition, Visual, Photic Stimulation, Prefrontal Cortex, Research Support, Non-U.S. Gov't, U.S. Gov't, P.H.S., Visual Perception, Choice Behavior, Cognition, Dopamine, Learning, Schizophrenia, Substance-Related Disorders, Generalization (Psychology), Motor Skills, Non-P.H.S., Nerve Net, Neuronal Plasticity, Perception, Cerebral Cortex, Memory, Neurons, Sound Localization, Synapses, Synaptic Transmission, 15483601},
}

@article{behrmann_parietal_2004,
	title = {Parietal cortex and attention},
	volume = {14},
	abstract = {The parietal lobe forms about 20\% of the human cerebral cortex and is divided into two major regions, the somatosensory cortex and the posterior parietal cortex. Posterior parietal cortex, located at the junction of multiple sensory regions, projects to several cortical and subcortical areas and is engaged in a host of cognitive operations. One such operation is selective attention, the process where by the input is filtered and a subset of the information is selected for preferential processing. Recent neuroimaging and neuropsychological studies have provided a more fine-grained understanding of the relationship between brain and behavior in the domain of selective attention.},
	number = {2},
	journal = {Curr Opin Neurobiol},
	author = {Behrmann, M and Geng, J J and Shomstein, S},
	year = {2004},
	pmid = {15082327},
	keywords = {Attention/*physiology, Cues, Humans, Magnetic Resonance Imaging, Neural Pathways/anatomy \& histology/*physiology, Parietal Lobe/anatomy \& histology/*physiology, Perception/physiology, Perceptual Disorders/pathology/physiopathology, Psychomotor Performance/physiology, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., Sensation/physiology},
	pages = {212--217},
}

@Article{Gil-da-Costa2004,
  author   = {Ricardo Gil-da-Costa and Allen Braun and Marco Lopes and Marc D Hauser and Richard E Carson and Peter Herscovitch and Alex Martin},
  journal  = {Proc Natl Acad Sci U S A},
  title    = {Toward an evolutionary perspective on conceptual representation: {S}pecies-specific calls activate visual and affective processing systems in the macaque.},
  year     = {2004},
  number   = {50},
  pages    = {17516-21},
  volume   = {101},
  abstract = {Non-human primates produce a diverse repertoire of species-specific
	calls and have rich conceptual systems. Some of their calls are designed
	to convey information about concepts such as predators, food, and
	social relationships, as well as the affective state of the caller.
	Little is known about the neural architecture of these calls, and
	much of what we do know is based on single-cell physiology from anesthetized
	subjects. By using positron emission tomography in awake rhesus macaques,
	we found that conspecific vocalizations elicited activity in higher-order
	visual areas, including regions in the temporal lobe associated with
	the visual perception of object form (TE/TEO) and motion (superior
	temporal sulcus) and storing visual object information into long-term
	memory (TE), as well as in limbic (the amygdala and hippocampus)
	and paralimbic regions (ventromedial prefrontal cortex) associated
	with the interpretation and memory-encoding of highly salient and
	affective material. This neural circuitry strongly corresponds to
	the network shown to support representation of conspecifics and affective
	information in humans. These findings shed light on the evolutionary
	precursors of conceptual representation in humans, suggesting that
	monkeys and humans have a common neural substrate for representing
	object concepts.},
  doi      = {10.1073/pnas.0408077101},
  keywords = {Acoustic Stimulation, Animals, Brain, Concept Formation, Electrophysiology, Evolution, Female, Macaca mulatta, Magnetic Resonance Imaging, Male, Positron-Emission Tomography, Research Support, Non-U.S. Gov't, U.S. Gov't, P.H.S., Species Specificity, Visual Perception, Vocalization, Animal, 15583132},
}

@Article{Mellars2004,
  author   = {Paul Mellars},
  journal  = {Nature},
  title    = {Neanderthals and the modern human colonization of {E}urope.},
  year     = {2004},
  number   = {7016},
  pages    = {461-5},
  volume   = {432},
  abstract = {The fate of the Neanderthal populations of Europe and western Asia
	has gripped the popular and scientific imaginations for the past
	century. Following at least 200,000 years of successful adaptation
	to the glacial climates of northwestern Eurasia, they disappeared
	abruptly between 30,000 and 40,000 years ago, to be replaced by populations
	all but identical to modern humans. Recent research suggests that
	the roots of this dramatic population replacement can be traced far
	back to events on another continent, with the appearance of distinctively
	modern human remains and artefacts in eastern and southern Africa.},
  doi      = {10.1038/nature03103},
  keywords = {Animals, Attention, Brain, Decision Making, Face, Female, Haplorhini, Housing, Humans, Magnetic Resonance Imaging, Male, Models, Neurological, Pattern Recognition, Visual, Photic Stimulation, Prefrontal Cortex, Research Support, Non-U.S. Gov't, U.S. Gov't, P.H.S., Visual Perception, Choice Behavior, Cognition, Dopamine, Learning, Schizophrenia, Substance-Related Disorders, Generalization (Psychology), Motor Skills, Non-P.H.S., Nerve Net, Neuronal Plasticity, Perception, Cerebral Cortex, Memory, Neurons, Sound Localization, Synapses, Synaptic Transmission, Neural Pathways, Non-, Acoustic Stimulation, Adult, Age of Onset, Aging, Blindness, Child, Preschool, Infant, Newborn, Pitch Perception, Analysis of Variance, Animal Welfare, Laboratory, Behavior, Animal, Hybridization, Genetic, Maze Learning, Mice, Inbred C57BL, Inbred DBA, Phenotype, Reproducibility of Results, Darkness, Deafness, Finches, Sleep, Sound, Sunlight, Time Factors, Vocalization, Energy Metabolism, Evolution, Fossils, History, Ancient, Hominidae, Biological, Physical Endurance, Running, Skeleton, Walking, Acoustics, Auditory Perception, Cues, Discrimination Learning, Pair Bond, Social Behavior, Songbirds, Adolescent, England, Habituation (Psychophysiology), Korea, Language, Semantics, Vocabulary, Action Potentials, Hippocampus, Pyramidal Cells, Rats, Rotation, Australia, Brachyura, Cooperative Behavior, Logistic Models, Territoriality, Africa, Archaeology, Emigration and Immigration, Europe, Geography, Phylogeny, Population Dynamics, 15565144},
}

@Article{Tsodyks2004,
  author   = {Misha Tsodyks and Charles Gilbert},
  journal  = {Nature},
  title    = {Neural networks and perceptual learning.},
  year     = {2004},
  number   = {7010},
  pages    = {775-81},
  volume   = {431},
  abstract = {Sensory perception is a learned trait. The brain strategies we use
	to perceive the world are constantly modified by experience. With
	practice, we subconsciously become better at identifying familiar
	objects or distinguishing fine details in our environment. Current
	theoretical models simulate some properties of perceptual learning,
	but neglect the underlying cortical circuits. Future neural network
	models must incorporate the top-down alteration of cortical function
	by expectation or perceptual tasks. These newly found dynamic processes
	are challenging earlier views of static and feedforward processing
	of sensory information.},
  doi      = {10.1038/nature03013},
  keywords = {Animals, Attention, Brain, Decision Making, Face, Female, Haplorhini, Housing, Humans, Magnetic Resonance Imaging, Male, Models, Neurological, Pattern Recognition, Visual, Photic Stimulation, Prefrontal Cortex, Research Support, Non-U.S. Gov't, U.S. Gov't, P.H.S., Visual Perception, Choice Behavior, Cognition, Dopamine, Learning, Schizophrenia, Substance-Related Disorders, Generalization (Psychology), Motor Skills, Non-P.H.S., Nerve Net, Neuronal Plasticity, Perception, 15483598},
}

@Article{Piazza2004,
  author   = {Manuela Piazza and V\'eronique Izard and Philippe Pinel and Denis Le Bihan and Stanislas Dehaene},
  journal  = {Neuron},
  title    = {Tuning curves for approximate numerosity in the human intraparietal sulcus.},
  year     = {2004},
  number   = {3},
  pages    = {547-55},
  volume   = {44},
  abstract = {Number, like color or movement, is a basic property of the environment.
	Recently, single neurons tuned to number have been observed in animals.
	We used both psychophysics and neuroimaging to examine whether a
	similar neural coding scheme is present in humans. When participants
	viewed sets of items with a variable number, the bilateral intraparietal
	sulci responded selectively to number change. Functionally, the shape
	of this response indicates that humans, like other animal species,
	encode approximate number on a compressed internal scale. Anatomically,
	the intraparietal site coding for number in humans is compatible
	with that observed in macaque monkeys. Our results therefore suggest
	an evolutionary basis for human elementary arithmetic.},
  doi      = {10.1016/j.neuron.2004.10.014},
  keywords = {Adult, Brain Mapping, Cerebral Cortex, Choice Behavior, Comparative Study, Humans, Laterality, Magnetic Resonance Imaging, Non-U.S. Gov't, Oxygen, Parietal Lobe, Photic Stimulation, Psychophysics, Research Support, Semantics, Size Perception, Visual Perception, 15504333},
}

@Article{VanMarle2003,
  author   = {Kristy VanMarle and Brian J Scholl},
  journal  = {Psychol Sci},
  title    = {Attentive tracking of objects versus substances.},
  year     = {2003},
  number   = {5},
  pages    = {498-504},
  volume   = {14},
  abstract = {Recent research in vision science, infant cognition, and word learning
	suggests a special role for the processing of discrete objects. But
	what counts as an object? Answers to this question often depend on
	contrasting object-based processing with the processing of spatial
	areas or unbound visual features. In infant cognition and word learning,
	though, another salient contrast has been between rigid cohesive
	objects and nonsolid substances. Whereas objects may move from one
	location to another, a nonsolid substance must pour from one location
	to another. In the study reported here, we explored whether attentive
	tracking processes are sensitive to dynamic information of this type.
	Using a multiple-object tracking task, we found that subjects could
	easily track four items in a display of eight identical unpredictably
	moving entities that moved as discrete objects from one location
	to another, but could not track similar entities that noncohesively
	"poured" from one location to another-even when the items in both
	conditions followed the same trajectories at the same speeds. Other
	conditions revealed that this inability to track multiple "substances"
	stemmed not from violations of rigidity or cohesiveness per se, because
	subjects were able to track multiple noncohesive collections and
	multiple nonrigid deforming objects. Rather, the impairment was due
	to the dynamic extension and contraction during the substancelike
	motion, which rendered the location of the entity ambiguous. These
	results demonstrate a convergence between processes of midlevel adult
	vision and infant cognition, and in general help to clarify what
	can count as a persisting dynamic object of attention.},
  keywords = {Abscess, Adult, Age Factors, Animal, Animals, Anti-Bacterial Agents, Antimony Sodium Gluconate, Antineoplastic Agents, Antiviral Agents, Attention, Awareness, Axilla, Behavior, Biopsy, Bone and Bones, Breast Neoplasms, Carcinoma, Child Development, Chronic Disease, Clarithromycin, Cognition, Combined Modality Therapy, Computer-Assisted, Concept Formation, Consciousness, Cross Infection, Cues, Cytomegalovirus Infections, Discrimination (Psychology), Discrimination Learning, Distance Perception, Drainage, Ductal, Electrocoagulation, English Abstract, Extramural, Eye Movements, False Negative Reactions, Female, Field Dependence-Independence, Fine-Needle, Foscarnet, Ganciclovir, Health Care, Humans, Infant, Infant Behavior, Intervertebral Disk, Intraductal, Judgment, Legionnaires' Disease, Leishmaniasis, Liver Transplantation, Low Back Pain, Lumbar Vertebrae, Lymph Node Excision, Lymph Nodes, Lymphatic Metastasis, Macaca mulatta, Magnetic Resonance Imaging, Male, Mastitis, Memory, Middle Aged, Motion Perception, N.I.H., Neoadjuvant Therapy, Neoplasm Staging, Non-P.H.S., Non-U.S. Gov't, Noninfiltrating, Object Attachment, Optical Illusions, Orientation, Osteonecrosis, P.H.S., Pattern Recognition, Photic Stimulation, Postoperative Complications, Practice (Psychology), Practice Guidelines, Predictive Value of Tests, Problem Solving, Prognosis, Psychological Theory, Psychophysics, Puerperal Disorders, Quality Assurance, Reading, Reproducibility of Results, Research Support, Rotation, Schistosomicides, Semantics, Sentinel Lymph Node Biopsy, Set (Psychology), Short-Term, Space Perception, Surgery, Switzerland, Treatment Outcome, U.S. Gov't, Unconscious (Psychology), Viral Load, Visceral, Visual, Visual Perception, 12930483},
}

@Article{Pinker2002a,
  author   = {Steven Pinker and Michael T Ullman},
  journal  = {Trends Cogn Sci},
  title    = {The past and future of the past tense.},
  year     = {2002},
  number   = {11},
  pages    = {456-463},
  volume   = {6},
  abstract = {What is the interaction between storage and computation in language
	processing? What is the psychological status of grammatical rules?
	What are the relative strengths of connectionist and symbolic models
	of cognition? How are the components of language implemented in the
	brain? The English past tense has served as an arena for debates
	on these issues. We defend the theory that irregular past-tense forms
	are stored in the lexicon, a division of declarative memory, whereas
	regular forms can be computed by a concatenation rule, which requires
	the procedural system. Irregulars have the psychological, linguistic
	and neuropsychological signatures of lexical memory, whereas regulars
	often have the signatures of grammatical processing. Furthermore,
	because regular inflection is rule-driven, speakers can apply it
	whenever memory fails.},
  keywords = {Computing Methodologies, Human, Language, Learning, Mental Processes, Models, Theoretical, Stochastic Processes, Support, U.S. Gov't, Non-P.H.S., Cognition, Linguistics, Neural Networks (Computer), Practice (Psychology), Non-U.S. Gov't, Memory, Psychological, Task Performance and Analysis, Time Factors, Visual Perception, Adult, Attention, Discrimination Learning, Female, Male, Short-Term, Mental Recall, Orientation, Pattern Recognition, Visual, Perceptual Masking, Reading, Concept Formation, Form Perception, Animals, Corpus Striatum, Shrews, P.H.S., Visual Cortex, Visual Pathways, Acoustic Stimulation, Auditory Cortex, Auditory Perception, Cochlea, Ear, Gerbillinae, Glycine, Hearing, Neurons, Space Perception, Strychnine, Adolescent, Decision Making, Reaction Time, Astrocytoma, Brain Mapping, Brain Neoplasms, Cerebral Cortex, Electric Stimulation, Electrophysiology, Epilepsy, Temporal Lobe, Evoked Potentials, Frontal Lobe, Noise, Parietal Lobe, Scalp, Child, Language Development, Psycholinguistics, Brain, Perception, Speech, Vocalization, Animal, Discrimination (Psychology), Hippocampus, Rats, Calcium, Chelating Agents, Excitatory Postsynaptic Potentials, Glutamic Acid, Guanosine Diphosphate, In Vitro, Neuronal Plasticity, Pyramidal Cells, Receptors, AMPA, Metabotropic Glutamate, N-Methyl-D-Aspartate, Somatosensory Cortex, Synapses, Synaptic Transmission, Thionucleotides, Action Potentials, Calcium Channels, L-Type, Electric Conductivity, Entorhinal Cortex, Neurological, Long-Evans, Infant, Mathematics, Statistics, Probability Learning, Problem Solving, Psychophysics, Association Learning, Child Psychology, Habituation (Psychophysiology), Probability Theory, Analysis of Variance, Semantics, Symbolism, Behavior, Eye Movements, Macaca mulatta, Prefrontal Cortex, Cats, Dogs, Haplorhini, Photic Stimulation, Electroencephalography, Nervous System Physiology, Darkness, Grasshoppers, Light, Membrane Potentials, Neural Inhibition, Afferent, Picrotoxin, Vision, Deoxyglucose, Injections, Microspheres, Neural Pathways, Rhodamines, Choice Behavior, Speech Perception, Verbal Learning, Dominance, Cerebral, Fixation, Ocular, Language Tests, Random Allocation, Comparative Study, Saguinus, Sound Spectrography, Species Specificity, Audiometry, Auditory Threshold, Calibration, Data Interpretation, Statistical, Anesthesia, General, Electrodes, Implanted, Pitch Perception, Sound Localization, Paired-Associate Learning, Serial Learning, Auditory, Age Factors, Motion Perception, Brain Injuries, Computer Simulation, Blindness, Psychomotor Performance, Color Perception, Signal Detection (Psychology), Judgment, ROC Curve, Regression Analysis, Music, Probability, Arm, Cerebrovascular Disorders, Hemiplegia, Movement, Muscle, Skeletal, Myoclonus, Robotics, Magnetoencephalography, Phonetics, Software, Speech Production Measurement, Epilepsies, Partial, Laterality, Stereotaxic Techniques, Germany, Speech Acoustics, Verbal Behavior, Child Development, Instinct, Brain Stem, Coma, Diagnosis, Differential, Hearing Disorders, Hearing Loss, Central, Neuroma, Acoustic, Dendrites, Down-Regulation, Patch-Clamp Techniques, Wistar, Up-Regulation, Aged, Aphasia, Middle Aged, Cones (Retina), Primates, Retina, Retinal Ganglion Cells, Tympanic Membrane, Cell Communication, Extremities, Biological, Motor Activity, Rana catesbeiana, Spinal Cord, Central Nervous System, Motion, Motor Cortex, Intelligence, Macaca fascicularis, Adoption, Critical Period (Psychology), France, Korea, Magnetic Resonance Imaging, Multilingualism, Auditory Pathways, Cochlear Nerve, Loudness Perception, Neural Conduction, Sensory Thresholds, Sound, Language Disorders, 12457895},
}

@Article{Wolff2001,
  author   = {C Wolff and E Schr\"oger},
  journal  = {Brain Res Cogn Brain Res},
  title    = {Activation of the auditory pre-attentive change detection system by tone repetitions with fast stimulation rate.},
  year     = {2001},
  number   = {3},
  pages    = {323-7},
  volume   = {10},
  abstract = {The human automatic pre-attentive change detection system indexed
	by the mismatch negativity (MMN) component of the auditory event-related
	brain potential is known to be highly adaptive. The present study
	showed that even infrequent repetitions of tones can elicit MMN,
	independently of attention, when tones of varying frequency are rapidly
	presented in an isochronous rhythm. This demonstrates that frequency
	variation can be extracted as an invariant feature of the acoustic
	environment revealing the capacity for adaptation of the auditory
	pre-attentive change detection system. It is argued that this capacity
	is related to the temporal-window of integration.},
  keywords = {Computing Methodologies, Human, Language, Learning, Mental Processes, Models, Theoretical, Stochastic Processes, Support, U.S. Gov't, Non-P.H.S., Cognition, Linguistics, Neural Networks (Computer), Practice (Psychology), Non-U.S. Gov't, Memory, Psychological, Task Performance and Analysis, Time Factors, Visual Perception, Adult, Attention, Discrimination Learning, Female, Male, Short-Term, Mental Recall, Orientation, Pattern Recognition, Visual, Perceptual Masking, Reading, Concept Formation, Form Perception, Animals, Corpus Striatum, Shrews, P.H.S., Visual Cortex, Visual Pathways, Acoustic Stimulation, Auditory Cortex, Auditory Perception, Cochlea, Ear, Gerbillinae, Glycine, Hearing, Neurons, Space Perception, Strychnine, Adolescent, Decision Making, Reaction Time, Astrocytoma, Brain Mapping, Brain Neoplasms, Cerebral Cortex, Electric Stimulation, Electrophysiology, Epilepsy, Temporal Lobe, Evoked Potentials, Frontal Lobe, Noise, Parietal Lobe, Scalp, Child, Language Development, Psycholinguistics, Brain, Perception, Speech, Vocalization, Animal, Discrimination (Psychology), Hippocampus, Rats, Calcium, Chelating Agents, Excitatory Postsynaptic Potentials, Glutamic Acid, Guanosine Diphosphate, In Vitro, Neuronal Plasticity, Pyramidal Cells, Receptors, AMPA, Metabotropic Glutamate, N-Methyl-D-Aspartate, Somatosensory Cortex, Synapses, Synaptic Transmission, Thionucleotides, Action Potentials, Calcium Channels, L-Type, Electric Conductivity, Entorhinal Cortex, Neurological, Long-Evans, Infant, Mathematics, Statistics, Probability Learning, Problem Solving, Psychophysics, Association Learning, Child Psychology, Habituation (Psychophysiology), Probability Theory, Analysis of Variance, Semantics, Symbolism, Behavior, Eye Movements, Macaca mulatta, Prefrontal Cortex, Cats, Dogs, Haplorhini, Photic Stimulation, Electroencephalography, Nervous System Physiology, Darkness, Grasshoppers, Light, Membrane Potentials, Neural Inhibition, Afferent, Picrotoxin, Vision, Deoxyglucose, Injections, Microspheres, Neural Pathways, Rhodamines, Choice Behavior, Speech Perception, Verbal Learning, Dominance, Cerebral, Fixation, Ocular, Language Tests, Random Allocation, Comparative Study, Saguinus, Sound Spectrography, Species Specificity, Audiometry, Auditory Threshold, Calibration, Data Interpretation, Statistical, Anesthesia, General, Electrodes, Implanted, Pitch Perception, Sound Localization, Paired-Associate Learning, Serial Learning, Auditory, Age Factors, Motion Perception, Brain Injuries, Computer Simulation, Blindness, Psychomotor Performance, Color Perception, Signal Detection (Psychology), Judgment, ROC Curve, Regression Analysis, Music, Probability, Arm, Cerebrovascular Disorders, Hemiplegia, Movement, Muscle, Skeletal, Myoclonus, Robotics, Magnetoencephalography, Phonetics, Software, Speech Production Measurement, Epilepsies, Partial, Laterality, Stereotaxic Techniques, Germany, Speech Acoustics, Verbal Behavior, Child Development, Instinct, Brain Stem, Coma, Diagnosis, Differential, Hearing Disorders, Hearing Loss, Central, Neuroma, Acoustic, Dendrites, Down-Regulation, Patch-Clamp Techniques, Wistar, Up-Regulation, Aged, Aphasia, Middle Aged, Cones (Retina), Primates, Retina, Retinal Ganglion Cells, Tympanic Membrane, Cell Communication, Extremities, Biological, Motor Activity, Rana catesbeiana, Spinal Cord, Central Nervous System, Motion, Motor Cortex, Intelligence, Macaca fascicularis, Adoption, Critical Period (Psychology), France, Korea, Magnetic Resonance Imaging, Multilingualism, Auditory Pathways, Cochlear Nerve, Loudness Perception, Neural Conduction, Sensory Thresholds, Sound, Language Disorders, Preschool, Generalization (Psychology), Vocabulary, Biophysics, Nerve Net, Potassium Channels, Sodium Channels, Cues, Differential Threshold, Arousal, Newborn, Sucking Behavior, Ferrets, Microelectrodes, Gestalt Theory, Mathematical Computing, Perceptual Closure, Vestibulocochlear Nerve, Brain Damage, Chronic, Regional Blood Flow, Thinking, Tomography, Emission-Computed, Case-Control Studies, Multivariate Analysis, Artificial Intelligence, Depth Perception, Broca, Encephalitis, Herpes Simplex, Infarction, Middle Cerebral Artery, X-Ray Computed, 11167055},
}

@Article{Thoroughman2000,
  author   = {KA Thoroughman and R Shadmehr},
  journal  = {Nature},
  title    = {Learning of action through adaptive combination of motor primitives.},
  year     = {2000},
  number   = {6805},
  pages    = {742-7},
  volume   = {407},
  abstract = {Understanding how the brain constructs movements remains a fundamental
	challenge in neuroscience. The brain may control complex movements
	through flexible combination of motor primitives, where each primitive
	is an element of computation in the sensorimotor map that transforms
	desired limb trajectories into motor commands. Theoretical studies
	have shown that a system's ability to learn action depends on the
	shape of its primitives. Using a time-series analysis of error patterns,
	here we show that humans learn the dynamics of reaching movements
	through a flexible combination of primitives that have gaussian-like
	tuning functions encoding hand velocity. The wide tuning of the inferred
	primitives predicts limitations on the brain's ability to represent
	viscous dynamics. We find close agreement between the predicted limitations
	and the subjects' adaptation to new force fields. The mathematical
	properties of the derived primitives resemble the tuning curves of
	Purkinje cells in the cerebellum. The activity of these cells may
	encode primitives that underlie the learning of dynamics.},
  doi      = {10.1038/35037588},
  keywords = {Computing Methodologies, Human, Language, Learning, Mental Processes, Models, Theoretical, Stochastic Processes, Support, U.S. Gov't, Non-P.H.S., Cognition, Linguistics, Neural Networks (Computer), Practice (Psychology), Non-U.S. Gov't, Memory, Psychological, Task Performance and Analysis, Time Factors, Visual Perception, Adult, Attention, Discrimination Learning, Female, Male, Short-Term, Mental Recall, Orientation, Pattern Recognition, Visual, Perceptual Masking, Reading, Concept Formation, Form Perception, Animals, Corpus Striatum, Shrews, P.H.S., Visual Cortex, Visual Pathways, Acoustic Stimulation, Auditory Cortex, Auditory Perception, Cochlea, Ear, Gerbillinae, Glycine, Hearing, Neurons, Space Perception, Strychnine, Adolescent, Decision Making, Reaction Time, Astrocytoma, Brain Mapping, Brain Neoplasms, Cerebral Cortex, Electric Stimulation, Electrophysiology, Epilepsy, Temporal Lobe, Evoked Potentials, Frontal Lobe, Noise, Parietal Lobe, Scalp, Child, Language Development, Psycholinguistics, Brain, Perception, Speech, Vocalization, Animal, Discrimination (Psychology), Hippocampus, Rats, Calcium, Chelating Agents, Excitatory Postsynaptic Potentials, Glutamic Acid, Guanosine Diphosphate, In Vitro, Neuronal Plasticity, Pyramidal Cells, Receptors, AMPA, Metabotropic Glutamate, N-Methyl-D-Aspartate, Somatosensory Cortex, Synapses, Synaptic Transmission, Thionucleotides, Action Potentials, Calcium Channels, L-Type, Electric Conductivity, Entorhinal Cortex, Neurological, Long-Evans, Infant, Mathematics, Statistics, Probability Learning, Problem Solving, Psychophysics, Association Learning, Child Psychology, Habituation (Psychophysiology), Probability Theory, Analysis of Variance, Semantics, Symbolism, Behavior, Eye Movements, Macaca mulatta, Prefrontal Cortex, Cats, Dogs, Haplorhini, Photic Stimulation, Electroencephalography, Nervous System Physiology, Darkness, Grasshoppers, Light, Membrane Potentials, Neural Inhibition, Afferent, Picrotoxin, Vision, Deoxyglucose, Injections, Microspheres, Neural Pathways, Rhodamines, Choice Behavior, Speech Perception, Verbal Learning, Dominance, Cerebral, Fixation, Ocular, Language Tests, Random Allocation, Comparative Study, Saguinus, Sound Spectrography, Species Specificity, Audiometry, Auditory Threshold, Calibration, Data Interpretation, Statistical, Anesthesia, General, Electrodes, Implanted, Pitch Perception, Sound Localization, Paired-Associate Learning, Serial Learning, Auditory, Age Factors, Motion Perception, Brain Injuries, Computer Simulation, Blindness, Psychomotor Performance, Color Perception, Signal Detection (Psychology), Judgment, ROC Curve, Regression Analysis, Music, Probability, Arm, Cerebrovascular Disorders, Hemiplegia, Movement, Muscle, Skeletal, Myoclonus, Robotics, Magnetoencephalography, Phonetics, Software, Speech Production Measurement, Epilepsies, Partial, Laterality, Stereotaxic Techniques, Germany, Speech Acoustics, Verbal Behavior, Child Development, Instinct, Brain Stem, Coma, Diagnosis, Differential, Hearing Disorders, Hearing Loss, Central, Neuroma, Acoustic, Dendrites, Down-Regulation, Patch-Clamp Techniques, Wistar, Up-Regulation, Aged, Aphasia, Middle Aged, Cones (Retina), Primates, Retina, Retinal Ganglion Cells, Tympanic Membrane, Cell Communication, Extremities, Biological, Motor Activity, Rana catesbeiana, Spinal Cord, Central Nervous System, Motion, Motor Cortex, Intelligence, Macaca fascicularis, Adoption, Critical Period (Psychology), France, Korea, Magnetic Resonance Imaging, Multilingualism, Auditory Pathways, Cochlear Nerve, Loudness Perception, Neural Conduction, Sensory Thresholds, Sound, Language Disorders, Preschool, Generalization (Psychology), Vocabulary, Biophysics, Nerve Net, Potassium Channels, Sodium Channels, Cues, Differential Threshold, Arousal, Newborn, Sucking Behavior, Ferrets, Microelectrodes, Gestalt Theory, Mathematical Computing, Perceptual Closure, Vestibulocochlear Nerve, Brain Damage, Chronic, Regional Blood Flow, Thinking, Tomography, Emission-Computed, Case-Control Studies, Multivariate Analysis, Artificial Intelligence, Depth Perception, 11048700},
}

@article{lee_mapping_2000,
	title = {Mapping of functional organization in human visual cortex: electrical cortical stimulation},
	volume = {54},
	doi = {10/gpckkm},
	abstract = {OBJECTIVES: To investigate the pattern of functional organization in the human visual cortex through electrical cortical stimulation. METHODS: Electrical cortical stimulation was applied to the occipital cortex and adjacent cortices using subdural grid electrodes in 23 epilepsy patients. Diverse visual responses were recorded. These responses were divided into different categories according to the specific response modalities, such as form, color, and motion. Form visual responses were further subdivided into simple, intermediate, and complex responses. The cortical localization of subdural electrodes was identified using MRI-CT coregistration. The cortical distribution of different visual responses was projected into three-dimensional surface renderings of the brain. The distribution and frequency of subdural electrodes showing different visual responses were quantified by calculating the percentage of the number of electrodes showing one specific type of visual response at the corresponding anatomic region to the total number of electrodes in all brain regions that produced the same response. RESULTS: Simple form responses were obtained mostly at the occipital pole and the inferior occipital gyrus (47.4\%) and the striate cortex (42.4\%). Intermediate form responses occurred mainly on the peristriate cortex (52.5\%) and the lateral occipital (28.0\%) and fusiform gyri (19.5\%). Complex forms were produced by stimulation of the basal temporo-occipital region (57.6\%) and the lateral temporal or lateral temporo-occipital junctional region (42.4\%). Color responses occurred on the basal occipital area, mostly at the fusiform (40.0\%) and lingual gyri (36.0\%). Moving sensations were evoked by stimulation of the basal temporo-occipital (28.4\%) and the mesial parieto-occipital or temporo-parieto-occipital junctional regions (23.9\%). CONCLUSIONS: Different modalities of vision, such as form, color, and moving sensation, appeared to be distributed and organized in different areas of the human visual cortex.},
	number = {4},
	journal = {Neurology},
	author = {Lee, H.W. and Hong, S.B. and Seo, D.W. and Tae, W.S. and Hong, S.C.},
	year = {2000},
	keywords = {\#nosource, Adolescence, Adult, Brain Mapping, Electric Stimulation, Epilepsy/*pathology/*physiopathology, Female, Human, Magnetic Resonance Imaging, Male, Support, Non-U.S. Gov't, Visual Cortex/*pathology/*physiopathology},
	pages = {849--54},
}

@article{beschin_perceiving_2000,
	title = {Perceiving left and imagining right: dissociation in neglect},
	volume = {36},
	doi = {10.1016/S0010-9452(08)70849-9},
	abstract = {Signor Piazza, a patient with a left parieto-occipital haemorrhage and a right thalamic stroke, showed severe right personal neglect (e.g. touching own body parts) and right perceptual neglect in tasks with (e.g. cancelling tasks) or without (e.g. description of a complex picture) motor response. He had also right-sided neglect dyslexia (including single words), without language impairments. However, the patient also presented with a clear left-sided deficit in the representational domain (e.g. imagery tasks). Signor Piazza's pattern of performance suggests dissociation between imagery and perception within the neglect syndrome.},
	number = {3},
	journal = {Cortex},
	author = {Beschin, N. and Basso, A. and Della Sala, S.},
	year = {2000},
	keywords = {\#nosource, Aged, Agnosia/*diagnosis, Brain Ischemia/diagnosis, Brain/pathology/radiography, Case Report, Cerebral Hemorrhage/diagnosis, Dyslexia/diagnosis, Human, Laterality/physiology, Magnetic Resonance Imaging, Male, Occipital Lobe/pathology/radiography, Parietal Lobe/pathology/radiography, Questionnaires, Severity of Illness Index, Thalamus/blood supply/pathology/radiography, Tomography, X-Ray Computed},
	pages = {401--414},
}

@Article{Marshuetz2000,
  author   = {C. Marshuetz and E. E. Smith and J. Jonides and J. DeGutis and T. L. Chenevert},
  journal  = {J Cogn Neurosci},
  title    = {Order information in working memory: f{MRI} evidence for parietal and prefrontal mechanisms.},
  year     = {2000},
  pages    = {130-44},
  volume   = {12 Suppl 2},
  abstract = {Working memory is thought to include a mechanism that allows for the
	coding of order information. One question of interest is how order
	information is coded, and how that code is neurally implemented.
	Here we report both behavioral and fMRI findings from an experiment
	involved comparing two tasks, an item-memory task and an order-memory
	task. In each case, five letters were presented for storage, followed
	after a brief interval by a set of probe letters. In the case of
	the item-memory task, the two letters were identical, and the subject
	responded to the question, "Was this letter one of the items you
	saw?". In the case of the order-memory task, the letters were different,
	and subjects responded to the question, "Are these two letters in
	the order in which you saw them?". Behaviorally, items that were
	further apart in the sequence that elicited faster reaction times
	and higher accuracy in the Order task. Areas that were significantly
	more activated in the Order condition included the parietal and prefrontal
	cortex. Parietal activations overlapped those involved in number
	processing, leading to the suggestion that the underlying representation
	of order and numbers may share a common process, coding for magnitude.},
  doi      = {10.1162/08989290051137459},
  keywords = {Brain Mapping, Cognition, Female, Functional Laterality, Humans, Magnetic Resonance Imaging, Male, Memory, Parietal Lobe, Pattern Recognition, Prefrontal Cortex, Reaction Time, Short-Term, Time Factors, Visual, 11506653},
}

@article{ohno_apraxic_2000,
	title = {Apraxic agraphia due to thalamic infarction},
	volume = {54},
	doi = {10/grrsrk},
	abstract = {The authors report a patient of pure apraxic agraphia with normal praxis due to left thalamic infarction. 15O-gas-PET showed reduced oxygen metabolism in the left thalamus and the left dorsolateral premotor area, while MRI and 11C-fulumazenil-PET showed no remarkable lesions in the frontal cortex. The patient's word imaging remained normal. The authors hypothesize that thalamic destruction causes pure apraxic agraphia by exerting a remote effect on left dorsolateral premotor area and blocking somewhere between graphemic area and motor programming.},
	number = {12},
	journal = {Neurology},
	author = {Ohno, T. and Bando, M. and Nagura, H. and Ishii, K. and Yamanouchi, H.},
	year = {2000},
	keywords = {\#nosource, Aged, Agraphia/diagnosis/*etiology, Brain Infarction/*complications/diagnosis, Case Report, Human, Language Tests, Magnetic Resonance Imaging, Male, Mediodorsal Thalamic Nucleus/blood supply/*pathology/radionuclide imaging, Neuropsychological Tests, Thalamic Diseases/*complications/diagnosis, Tomography, Emission-Computed},
	pages = {2336--2339},
}

@article{Epstein1998,
	title = {A cortical representation of the local visual environment},
	volume = {392},
	doi = {10.1038/33402},
	abstract = {Medial temporal brain regions such as the hippocampal formation and parahippocampal cortex have been generally implicated in navigation and visual memory. However, the specific function of each of these regions is not yet clear. Here we present evidence that a particular area within human parahippocampal cortex is involved in a critical component of navigation: perceiving the local visual environment. This region, which we name the 'parahippocampal place area' (PPA), responds selectively and automatically in functional magnetic resonance imaging (fMRI) to passively viewed scenes, but only weakly to single objects and not at all to faces. The critical factor for this activation appears to be the presence in the stimulus of information about the layout of local space. The response in the PPA to scenes with spatial layout but no discrete objects (empty rooms) is as strong as the response to complex meaningful scenes containing multiple objects (the same rooms furnished) and over twice as strong as the response to arrays of multiple objects without three-dimensional spatial context (the furniture from these rooms on a blank background). This response is reduced if the surfaces in the scene are rearranged so that they no longer define a coherent space. We propose that the PPA represents places by encoding the geometry of the local environment.},
	language = {eng},
	number = {6676},
	journal = {Nature},
	author = {Epstein, R and Kanwisher, N},
	year = {1998},
	pmid = {9560155},
	note = {ISBN: 0028-0836},
	keywords = {Brain Mapping, Face, Female, Hippocampus, Humans, Magnetic Resonance Imaging, Male, PPA, Photic Stimulation, Space Perception, Visual Perception, research support, non-u.s. gov't, research support, u.s. gov't, p.h.s.},
	pages = {598--601},
}

Paper  doi  abstract   bibtex   

@article{corbetta_common_1998,
	title = {A common network of functional areas for attention and eye movements},
	volume = {21},
	url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9808463},
	doi = {10.1016/S0896-6273(00)80593-0},
	abstract = {Functional magnetic resonance imaging (fMRI) and surface-based representations of brain activity were used to compare the functional anatomy of two tasks, one involving covert shifts of attention to peripheral visual stimuli, the other involving both attentional and saccadic shifts to the same stimuli. Overlapping regional networks in parietal, frontal, and temporal lobes were active in both tasks. This anatomical overlap is consistent with the hypothesis that attentional and oculomotor processes are tightly integrated at the neural level.},
	number = {4},
	journal = {Neuron},
	author = {Corbetta, M. and Akbudak, E. and Conturo, T.E. and Snyder, A.Z. and Ollinger, J.M. and Drury, H.A. and Linenweber, M.R. and Petersen, S.E. and Raichle, M.E. and Van Essen, D.C. and Shulman, G.L.},
	year = {1998},
	keywords = {\#nosource, Adolescent, Adult, Attention/*physiology, Behavior/physiology, Brain Mapping, Brain/*physiology, Female, Humans, Magnetic Resonance Imaging, Male, Neural Pathways/physiology, Photic Stimulation, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S., Saccades/*physiology},
	pages = {761--73},
}

@article{
 title = {Uptake of plutonium by the human liver},
 type = {article},
 year = {1998},
 keywords = {/sup 237/Pu,/sup 237/Pu-loaded phantoms,Accumulation,Anatomical data,Biomedical MRI,Biotransport,Calibration,Health hazards,Healthy subjects,Hepatic uptake,Human liver,Individual subjects,Liver,Lower thorax,Magnetic resonance imaging,Metabolic models,Plutonium,Pu,Pu(IV) citrate,Radioisotopes,Right lateral surfaces,Scintillation counter},
 pages = {385-395},
 volume = {80},
 id = {bb0a5a78-2aeb-33cd-9344-577abd4dd7b9},
 created = {2015-02-12T14:35:43.000Z},
 file_attached = {false},
 profile_id = {81af7548-db00-3f00-bfa0-1774347c59e1},
 group_id = {63e349d6-2c70-3938-9e67-2f6483f6cbab},
 last_modified = {2015-02-12T20:21:04.000Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 source_type = {Journal Article},
 notes = {<m:note>Article<m:linebreak/>Nuclear Technology Publishing</m:note>},
 abstract = {The hepatic uptake of /sup 237/Pu in 12 healthy subjects who received it intravenously as Pu(IV) citrate is reported. The results were derived from the response of a scintillation counter viewing the right lateral surfaces of the lower thorax; calibration for individual subjects was performed with /sup 237/Pu-loaded phantoms based on anatomical data from magnetic resonance imaging. The highest levels (mean 73+or-12 (sd) % of injection) were reached variously after 7-230 days, with no conclusive evidence of a subsequent reduction; half of the accumulation occurred within 1-2 days. This uptake is much greater than predicted by the ICRP's present or previous metabolic models for plutonium, but the excess is strongly corroborated by other data from this study.},
 bibtype = {article},
 author = {Newton, D and Talbot, R J and Kang, C and Warner, A J},
 journal = {Radiation Protection Dosimetry},
 number = {4}
}

@article{ hommet_bilateral_1998,
  title = {Bilateral olivary hypertrophy and palatal myoclonus},
  volume = {49},
  issn = {0090-3019},
  abstract = {We report on a case of palatal myoclonus associated with olivary hypertrophy on magnetic resonance imaging ({MRI}) in a 63-year-old man. This rare radiological finding must be differentiated from a brainstem tumor.},
  language = {eng},
  number = {2},
  journal = {Surgical Neurology},
  author = {Hommet, C. D. and De Toffol, B. and Cottier, J. P. and Autret, A.},
  month = {February},
  year = {1998},
  pmid = {9457274},
  keywords = {Brain Neoplasms, Brain Stem, Diagnosis, Differential, Humans, Hypertrophy, Magnetic Resonance Imaging, Male, Middle Aged, Myoclonus, Olivary Nucleus, Palate, Soft},
  pages = {215--216}
}

Paper  doi  abstract   bibtex   

@article{danziger_inhibitory_1997,
	title = {Inhibitory tagging of locations in the blind field of hemianopic patients},
	volume = {6},
	url = {http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.idealibrary.com/links/citation/1053-8100/6/291},
	doi = {10/d6wx53},
	abstract = {This study evaluated the potential contribution of extrageniculate visual pathways to oculomotor orienting reflexes in hemianopic patients. It tested whether extrageniculate pathways mediate inhibition of return (IOR)-a phenomenon characterized by slowed target detections at recently stimulated locations (Posner \& Cohen, 1984). Because hemianopic subjects cannot overtly respond to stimuli presented within their hemianopic field, we utilized a spatial cueing paradigm that capitalized on the fact that IOR operates in spatiotopic coordinates. Subjects moved their eyes so that a cue and a target presented at the same spatial location were imaged successively onto blind and seeing portions of their retinas. One hemianopic patient showed a similar IOR effect from cues presented within both the seeing and the hemianopic fields. With a second hemianopic patient, only presentations of the cue to the subject's seeing field produced IOR. The explanation for this discrepancy is not evident. These observations highlight both the potential value and the pitfalls inherent in using "blindsight" as a window into human consciousness.},
	number = {2-3},
	journal = {Consciousness and Cognition},
	author = {Danziger, S. and Fendrich, R. and Rafal, R.D.},
	year = {1997},
	keywords = {Brain Ischemia/complications/pathology, Brain/pathology, Case Report, Hemianopsia/complications/*diagnosis, Human, Magnetic Resonance Imaging, Male, Middle Age, Reaction Time, Support, U.S. Gov't, P.H.S., Task Performance and Analysis},
	pages = {291--307},
}

@article{seki_efficacy_1995,
	title = {The efficacy of kinesthetic reading treatment for pure alexia},
	volume = {33},
	doi = {10/bd5t4s},
	abstract = {This paper presents an effective treatment for pure alexia by a type of single-case design, which we termed a "material-control single-case design" [Sugishita et al., Neuropsychologia, Vol. 31, 559-569, 1993]. Two patients with pure alexia were treated using kinesthetic reading (reading by tracing or copying the outline of each letter with the patient's finger). The results clearly demonstrated that both patients significantly improved their reading and copying performances. Their recovery of reading performance arose from improvement in copying. The results of tachistoscopic reading tests suggested that the patient obtained the ability to read without kinesthetic movements.},
	number = {5},
	journal = {Neuropsychologia},
	author = {Seki, K. and Yajima, M. and Sugishita, M.},
	year = {1995},
	keywords = {\#nosource, *Kinesthesis, Adult, Brain/*physiopathology, Case Report, Dyslexia, Acquired/diagnosis/physiopathology/*therapy, Human, Language Disorders/etiology/therapy, Language Therapy, Magnetic Resonance Imaging, Male, Support, Non-U.S. Gov't, Thrombosis/complications/diagnosis/*physiopathology},
	pages = {595--609},
}

Paper  abstract   bibtex   

@article{
 title = {Intramedullary spinal cord ependymomas--a study of 45 cases with long-term follow-up.},
 type = {article},
 year = {1992},
 identifiers = {[object Object]},
 keywords = {Adolescent,Adult,Aged,Child,Child, Preschool,Combined Modality Therapy,Ependymoma,Ependymoma: diagnosis,Ependymoma: radiotherapy,Ependymoma: surgery,Female,Follow-Up Studies,Humans,Magnetic Resonance Imaging,Male,Middle Aged,Neoplasm Recurrence, Local,Neoplasm Recurrence, Local: diagnosis,Neoplasm Recurrence, Local: radiotherapy,Neoplasm Recurrence, Local: surgery,Neurologic Examination,Reoperation,Retrospective Studies,Spinal Cord Neoplasms,Spinal Cord Neoplasms: diagnosis,Spinal Cord Neoplasms: radiotherapy,Spinal Cord Neoplasms: surgery},
 pages = {74-9},
 volume = {119},
 websites = {http://www.ncbi.nlm.nih.gov/pubmed/1481757},
 month = {1},
 id = {08111960-a49a-3d5e-890c-10bb4dbadd57},
 created = {2013-09-04T15:14:24.000Z},
 file_attached = {true},
 profile_id = {8c4ca2d5-86de-3b5d-86be-8408415f34e0},
 group_id = {a484ae4c-fcac-3c7e-9ac3-3fad0df719a2},
 last_modified = {2014-11-22T16:36:55.000Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 abstract = {Of the 62 patients with intramedullary spinal cord ependymoma treated surgically at our Neurosurgery Division between January 1951 and December 1990 45 had a follow-up of at least 3 years and the longest 30 years. The 28 conus-cauda equina-filum ependymomas operated during the same period are not considered in this study. An analysis of our cases and of the larger published series shows that favourable prognostic factors, apart of course from total tumour removal, which is now usually possible, are a site below the high cervical segments and a mild pre-operative symptom pattern. Patient age at diagnosis, tumour size and "low dose" (< 40 Gy) radiotherapy seem to have no influence on the prognosis. Aggressive surgical removal is the treatment of choice and also for long-term recurrence.},
 bibtype = {article},
 author = {Ferrante, L and Mastronardi, L and Celli, P and Lunardi, P and Acqui, M and Fortuna, a},
 journal = {Acta Neurochirurgica},
 number = {1-4}
}

@article{rosen_perfusion_1989,
	title = {Perfusion imaging by nuclear magnetic resonance},
	volume = {5},
	issn = {0899-9422},
	language = {eng},
	number = {4},
	journal = {Magnetic Resonance Quarterly},
	author = {Rosen, B. R. and Belliveau, J. W. and Chien, D.},
	month = oct,
	year = {1989},
	pmid = {2701285},
	keywords = {Contrast Media, Hemodynamics, Humans, Magnetic Resonance Imaging, Regional Blood Flow},
	pages = {263--281}
}

@Article{Phillips1985,
  author   = {DP Phillips and JR Mendelson and MS Cynader and RM Douglas},
  journal  = {Exp Brain Res},
  title    = {Responses of single neurones in cat auditory cortex to time-varying stimuli: {F}requency-modulated tones of narrow excursion.},
  year     = {1985},
  number   = {3},
  pages    = {443-54},
  volume   = {58},
  abstract = {In the primary auditory cortex of cats anaesthetized with nitrous
	oxide, single neurones were examined with respect to their responses
	to tone bursts and linear modulations of the frequency of an on-going
	continuous tone. Using FM ramps of 2.0 kHz excursion and varying
	centre frequency, each of 39 neurones was examined for its preference
	for the direction of frequency change of a ramp whose centre frequency
	was varied in and around the neurone's response area. Direction preference
	was strictly associated with the slopes of the cell's spike count-versus-frequency
	function over the frequency range covered by the ramp. Preferences
	for upward- and downward-directed ramps were associated with the
	low- and high-frequency slopes of the spike count function, respectively.
	The strength of the cell's direction preference was associated with
	the relative steepness of the spike count function over the frequency
	range covered by the ramp. The timing of discharges elicited by the
	frequency modulations was found to be the sum of the cell's latent
	period for tone bursts plus the time after ramp onset that the stimulus
	frequency fell within the neurone's response area. The implications
	of these data for the processing of narrow and broad frequency-modulated
	ramps are discussed.},
  keywords = {Computing Methodologies, Human, Language, Learning, Mental Processes, Models, Theoretical, Stochastic Processes, Support, U.S. Gov't, Non-P.H.S., Cognition, Linguistics, Neural Networks (Computer), Practice (Psychology), Non-U.S. Gov't, Memory, Psychological, Task Performance and Analysis, Time Factors, Visual Perception, Adult, Attention, Discrimination Learning, Female, Male, Short-Term, Mental Recall, Orientation, Pattern Recognition, Visual, Perceptual Masking, Reading, Concept Formation, Form Perception, Animals, Corpus Striatum, Shrews, P.H.S., Visual Cortex, Visual Pathways, Acoustic Stimulation, Auditory Cortex, Auditory Perception, Cochlea, Ear, Gerbillinae, Glycine, Hearing, Neurons, Space Perception, Strychnine, Adolescent, Decision Making, Reaction Time, Astrocytoma, Brain Mapping, Brain Neoplasms, Cerebral Cortex, Electric Stimulation, Electrophysiology, Epilepsy, Temporal Lobe, Evoked Potentials, Frontal Lobe, Noise, Parietal Lobe, Scalp, Child, Language Development, Psycholinguistics, Brain, Perception, Speech, Vocalization, Animal, Discrimination (Psychology), Hippocampus, Rats, Calcium, Chelating Agents, Excitatory Postsynaptic Potentials, Glutamic Acid, Guanosine Diphosphate, In Vitro, Neuronal Plasticity, Pyramidal Cells, Receptors, AMPA, Metabotropic Glutamate, N-Methyl-D-Aspartate, Somatosensory Cortex, Synapses, Synaptic Transmission, Thionucleotides, Action Potentials, Calcium Channels, L-Type, Electric Conductivity, Entorhinal Cortex, Neurological, Long-Evans, Infant, Mathematics, Statistics, Probability Learning, Problem Solving, Psychophysics, Association Learning, Child Psychology, Habituation (Psychophysiology), Probability Theory, Analysis of Variance, Semantics, Symbolism, Behavior, Eye Movements, Macaca mulatta, Prefrontal Cortex, Cats, Dogs, Haplorhini, Photic Stimulation, Electroencephalography, Nervous System Physiology, Darkness, Grasshoppers, Light, Membrane Potentials, Neural Inhibition, Afferent, Picrotoxin, Vision, Deoxyglucose, Injections, Microspheres, Neural Pathways, Rhodamines, Choice Behavior, Speech Perception, Verbal Learning, Dominance, Cerebral, Fixation, Ocular, Language Tests, Random Allocation, Comparative Study, Saguinus, Sound Spectrography, Species Specificity, Audiometry, Auditory Threshold, Calibration, Data Interpretation, Statistical, Anesthesia, General, Electrodes, Implanted, Pitch Perception, Sound Localization, Paired-Associate Learning, Serial Learning, Auditory, Age Factors, Motion Perception, Brain Injuries, Computer Simulation, Blindness, Psychomotor Performance, Color Perception, Signal Detection (Psychology), Judgment, ROC Curve, Regression Analysis, Music, Probability, Arm, Cerebrovascular Disorders, Hemiplegia, Movement, Muscle, Skeletal, Myoclonus, Robotics, Magnetoencephalography, Phonetics, Software, Speech Production Measurement, Epilepsies, Partial, Laterality, Stereotaxic Techniques, Germany, Speech Acoustics, Verbal Behavior, Child Development, Instinct, Brain Stem, Coma, Diagnosis, Differential, Hearing Disorders, Hearing Loss, Central, Neuroma, Acoustic, Dendrites, Down-Regulation, Patch-Clamp Techniques, Wistar, Up-Regulation, Aged, Aphasia, Middle Aged, Cones (Retina), Primates, Retina, Retinal Ganglion Cells, Tympanic Membrane, Cell Communication, Extremities, Biological, Motor Activity, Rana catesbeiana, Spinal Cord, Central Nervous System, Motion, Motor Cortex, Intelligence, Macaca fascicularis, Adoption, Critical Period (Psychology), France, Korea, Magnetic Resonance Imaging, Multilingualism, Auditory Pathways, Cochlear Nerve, Loudness Perception, Neural Conduction, 4007088},
}

@Article{Phillips1984,
  author   = {DP Phillips and SS Orman},
  journal  = {J Neurophysiol},
  title    = {Responses of single neurons in posterior field of cat auditory cortex to tonal stimulation.},
  year     = {1984},
  note     = {as cited by \citeNP{Heil1998}},
  number   = {1},
  pages    = {147-63},
  volume   = {51},
  abstract = {In the auditory cortex of barbiturate-anesthetized cats, the posterior
	auditory field (field P) was identified by its tonotopic organization,
	and single neurons in that field were studied quantitatively for
	their sensitivity to the frequency and intensity of tonal stimuli
	presented via calibrated, sealed stimulating systems. Field P neurons
	had narrow, V-shaped, threshold frequency tuning curves. At suprathreshold
	levels, spike counts were generally greatest at frequencies at or
	close to the neuron's threshold best frequency (BF). Eighty-six percent
	of posterior-field neurons displayed spike counts that were a nonmonotonic
	function of the intensity of a BF tone. Of these, over 90\% showed
	at least a 50\% reduction in spike count at high stimulus levels,
	and almost 20\% of nonmonotonic cells ceased responding entirely
	at high stimulus intensities. The nonmonotonic shape of spike count-versus-intensity
	profiles was typically preserved across the range of frequencies
	to which any given neuron was responsive. For some neurons, this
	had the consequence of generating a completely circumscribed frequency-intensity
	response area. That is, these neurons responded to a tonal stimulus
	only if the stimulus was within a restricted range of both frequency
	and intensity. These response areas showed internal organizations
	that appeared to reflect one or both of two processes. For some neurons,
	the optimal sound pressure level for spike counts varied with tone
	frequency, roughly paralleling the threshold tuning curve. For other
	neurons, the optimal sound pressure level tended to be constant across
	frequency despite threshold variations of up to 20 dB. The minimum
	response latencies of posterior-field neurons were generally in the
	range of 20-50 ms, while cells in the primary auditory cortex (AI)
	in the same animals generally had minimum latent periods of less
	than 20 ms. Comparison of these data with those previously presented
	for neurons in two other cortical auditory fields suggests that the
	cat's auditory cortex might show an interfield segregation of neurons
	according to their coding properties.},
  keywords = {Computing Methodologies, Human, Language, Learning, Mental Processes, Models, Theoretical, Stochastic Processes, Support, U.S. Gov't, Non-P.H.S., Cognition, Linguistics, Neural Networks (Computer), Practice (Psychology), Non-U.S. Gov't, Memory, Psychological, Task Performance and Analysis, Time Factors, Visual Perception, Adult, Attention, Discrimination Learning, Female, Male, Short-Term, Mental Recall, Orientation, Pattern Recognition, Visual, Perceptual Masking, Reading, Concept Formation, Form Perception, Animals, Corpus Striatum, Shrews, P.H.S., Visual Cortex, Visual Pathways, Acoustic Stimulation, Auditory Cortex, Auditory Perception, Cochlea, Ear, Gerbillinae, Glycine, Hearing, Neurons, Space Perception, Strychnine, Adolescent, Decision Making, Reaction Time, Astrocytoma, Brain Mapping, Brain Neoplasms, Cerebral Cortex, Electric Stimulation, Electrophysiology, Epilepsy, Temporal Lobe, Evoked Potentials, Frontal Lobe, Noise, Parietal Lobe, Scalp, Child, Language Development, Psycholinguistics, Brain, Perception, Speech, Vocalization, Animal, Discrimination (Psychology), Hippocampus, Rats, Calcium, Chelating Agents, Excitatory Postsynaptic Potentials, Glutamic Acid, Guanosine Diphosphate, In Vitro, Neuronal Plasticity, Pyramidal Cells, Receptors, AMPA, Metabotropic Glutamate, N-Methyl-D-Aspartate, Somatosensory Cortex, Synapses, Synaptic Transmission, Thionucleotides, Action Potentials, Calcium Channels, L-Type, Electric Conductivity, Entorhinal Cortex, Neurological, Long-Evans, Infant, Mathematics, Statistics, Probability Learning, Problem Solving, Psychophysics, Association Learning, Child Psychology, Habituation (Psychophysiology), Probability Theory, Analysis of Variance, Semantics, Symbolism, Behavior, Eye Movements, Macaca mulatta, Prefrontal Cortex, Cats, Dogs, Haplorhini, Photic Stimulation, Electroencephalography, Nervous System Physiology, Darkness, Grasshoppers, Light, Membrane Potentials, Neural Inhibition, Afferent, Picrotoxin, Vision, Deoxyglucose, Injections, Microspheres, Neural Pathways, Rhodamines, Choice Behavior, Speech Perception, Verbal Learning, Dominance, Cerebral, Fixation, Ocular, Language Tests, Random Allocation, Comparative Study, Saguinus, Sound Spectrography, Species Specificity, Audiometry, Auditory Threshold, Calibration, Data Interpretation, Statistical, Anesthesia, General, Electrodes, Implanted, Pitch Perception, Sound Localization, Paired-Associate Learning, Serial Learning, Auditory, Age Factors, Motion Perception, Brain Injuries, Computer Simulation, Blindness, Psychomotor Performance, Color Perception, Signal Detection (Psychology), Judgment, ROC Curve, Regression Analysis, Music, Probability, Arm, Cerebrovascular Disorders, Hemiplegia, Movement, Muscle, Skeletal, Myoclonus, Robotics, Magnetoencephalography, Phonetics, Software, Speech Production Measurement, Epilepsies, Partial, Laterality, Stereotaxic Techniques, Germany, Speech Acoustics, Verbal Behavior, Child Development, Instinct, Brain Stem, Coma, Diagnosis, Differential, Hearing Disorders, Hearing Loss, Central, Neuroma, Acoustic, Dendrites, Down-Regulation, Patch-Clamp Techniques, Wistar, Up-Regulation, Aged, Aphasia, Middle Aged, Cones (Retina), Primates, Retina, Retinal Ganglion Cells, Tympanic Membrane, Cell Communication, Extremities, Biological, Motor Activity, Rana catesbeiana, Spinal Cord, Central Nervous System, Motion, Motor Cortex, Intelligence, Macaca fascicularis, Adoption, Critical Period (Psychology), France, Korea, Magnetic Resonance Imaging, Multilingualism, Auditory Pathways, Cochlear Nerve, Loudness Perception, 6693932},
}

@article{zhang_factors_2016,
	title = {Factors associated with meniscal body extrusion on knee {MRI} in overweight and obese women},
	issn = {1522-9653},
	doi = {10.1016/j.joca.2016.12.001},
	abstract = {{OBJECTIVE}: To determine factors associated with higher degree of meniscal body extrusion in overweight and obese women at high risk of knee osteoarthritis ({OA}).
{DESIGN}: We used baseline data of the {PROOF} study, Netherlands, comprising overweight or obese women aged 50 to 60 years, free of clinical knee {OA}. All subjects completed a questionnaire on knee complaints and physical activity, underwent physical examination, radiography, and 1.5 Tesla {MRI} of both knees. Using the mid-coronal {MRI} slice, one blinded observer measured tibial plateau width and meniscal body extrusion of both menisci in both knees. The association between baseline factors and meniscal extrusion, were analyzed with a random effects regression model. In addition, we used a fixed effect regression model for evaluation of knee-specific factors.
{RESULTS}: Mean age of the included women (n=395) was 55.7 years and mean body mass index 32.4 kg/m(2). Of all knees, 23\% had an absolute medial meniscus body extrusion ≥3.0 mm and 4\% had lateral meniscus body extrusion ≥3.0 mm. In the multivariable model, the medial meniscus extrusion was increased by 0.44 mm (95\% confidence interval [{CI}] 0.11, 0.77) when a medial meniscus tear was present, by 0.20 mm per 5 kg/m(2) (95\% {CI} 0.05, 0.35) increase in body mass index and by 0.25 in the presence of mild knee symptoms (95\% {CI} 0.05 to 0.44). Kellgren-Lawrence grade ≥1 and tibia width were associated with increased both medial and lateral extrusion.
{CONCLUSION}: In women, ipsilateral meniscus tear and high body mass index are factors associated with medial meniscus body extrusion.},
	journaltitle = {Osteoarthritis and Cartilage},
	shortjournal = {Osteoarthr. Cartil.},
	author = {Zhang, Fan and Bierma-Zeinstra, Sita M. and Oei, Edwin H. G. and Turkiewicz, Aleksandra and Englund, Martin and Runhaar, Jos},
	date = {2016-12-07},
	pmid = {27939623},
	keywords = {Knee, Magnetic resonance imaging, Meniscus, Osteoarthritis, women}
}

@article{neuman_longitudinal_2011,
	title = {Longitudinal assessment of femoral knee cartilage quality using contrast enhanced {MRI} ({dGEMRIC}) in patients with anterior cruciate ligament injury--comparison with asymptomatic volunteers},
	volume = {19},
	issn = {1522-9653},
	doi = {10.1016/j.joca.2011.05.002},
	abstract = {{OBJECTIVE}: In this observational longitudinal study we estimate knee joint cartilage glycosaminoglycan ({GAG}) content, in patients with an acute anterior cruciate ligament ({ACL}) injury, with or without a concomitant meniscus injury.
{METHODS}: 29 knees (19 men/10 women) were prospectively examined by repeat delayed gadolinium-enhanced magnetic resonance imaging of cartilage ({dGEMRIC}), approximately 3 weeks and 2.3±1.3 (range 4.5) years after the injury. We estimated the {GAG} content (T1Gd) in the central weight-bearing parts of the medial and lateral femoral cartilage and compared results with a reference cohort (n=24) with normal knees and no history of injury examined by {dGEMRIC} at one occasion previously.
{RESULTS}: The healthy reference group had longer T1Gd values compared with the {ACL}-injured patients at follow-up both medially: 428±38 vs 363±61ms (P{\textless}0.0001) and laterally: 445±41 vs 396±48ms (P=0.0002). At follow-up T1Gd was lower in meniscectomized patients compared to those without a meniscectomy, both medially (-84ms, P=0.002) and laterally (-38ms, P=0.05). In the injured group, the medial femoral cartilage showed similar T1Gd at the two {dGEMRIC} investigations: 357±50 vs 363±61ms (P=0.57), whereas the lateral femoral cartilage T1Gd increased: 374±48 vs 396±48ms (P=0.04).
{CONCLUSIONS}: The general decrease in cartilage T1Gd in {ACL}-injured patients compared with references provide evidence for structural matrix {GAG} changes that seem more pronounced if a concomitant meniscal injury is present. The fact that post-traumatic {OA} commonly develops in {ACL}-injured patients, in particularly those with meniscectomy, suggests that shorter T1Gd may be an early biomarker for {OA}.},
	pages = {977--983},
	number = {8},
	journaltitle = {Osteoarthritis and cartilage / {OARS}, Osteoarthritis Research Society},
	shortjournal = {Osteoarthr. Cartil.},
	author = {Neuman, P. and Tjörnstrand, J. and Svensson, J. and Ragnarsson, C. and Roos, H. and Englund, M. and Tiderius, C. J. and Dahlberg, L. E.},
	date = {2011-08},
	pmid = {21621622},
	keywords = {Adolescent, Adult, Anterior Cruciate Ligament, Cartilage, Articular, Case-Control Studies, Contrast Media, Female, Follow-Up Studies, Gadolinium {DTPA}, Glycosaminoglycans, Humans, Joint Diseases, Knee Joint, Longitudinal Studies, Magnetic resonance imaging, Male, Young Adult}
}