generated by bibbase.org
  2024 (8)
The intricacies of isomiRs: from classification to clinical relevance. Wagner, V.; Meese, E.; and Keller, A. Trends in genetics : TIG. 06 2024.
doi   link   bibtex  
Skin treatment with non-thermal plasma modulates the immune system through miR-223-3p and its target genes. Engel, A.; Ludwig, N.; Grandke, F.; Wagner, V.; Kern, F.; Fehlmann, T.; Schmartz, G.; Aparicio-Puerta, E.; Henn, D.; Walch-Rückheim, B.; Hannig, M.; Rupf, S.; Meese, E.; Laschke, M.; and Keller, A. RNA Biology, 21: 31-44. 06 2024.
doi   link   bibtex  
Prediction of diagnosis and diastolic filling pressure by AI-enhanced cardiac MRI: a modelling study of hospital data. Lehmann, undefined; Reich, C.; Kayvanpour, E.; Sedaghat-Hamedani, F.; Meder, M.; Haas, J.; Gomes, B.; Ashley, E.; Lehmann, D.; Gomes, B.; Vetter, N.; Braun, O.; Amr, A.; Hilbel, T.; Müller, J.; Köthe, U.; Reich, C.; Kayvanpour, E.; Sedaghat-Hamedani, F.; and Meder, B. The Lancet Digital Health, 6: e407-e417. 05 2024.
doi   link   bibtex  
Mibianto: ultra-efficient online microbiome analysis through k-mer based metagenomics. Hirsch, P.; Molano, L.; Engel, A.; Zentgraf, J.; Rahmann, S.; Hannig, M.; Müller, R.; Kern, F.; Keller, A.; and Schmartz, G. Nucleic acids research. 05 2024.
doi   link   bibtex  
Artificial Intelligence-Derived Risk Prediction: A Novel Risk Calculator Using Office and Ambulatory Blood Pressure. Guimarães, P.; Keller, A.; Böhm, M.; Lauder, L.; Fehlmann, T.; Ruilope, L.; Vinyoles, E.; Gorostidi, M.; Segura, J.; Ruiz-Hurtado, G.; Staplin, N.; Williams, B.; Sierra, A.; and Mahfoud, F. Hypertension (Dallas, Tex. : 1979). 04 2024.
doi   link   bibtex  
SingmiR: a single-cell miRNA alignment and analysis tool. Engel, A.; Rishik, S.; Hirsch, P.; Keller, V.; Fehlmann, T.; Kern, F.; and Keller, A. Nucleic acids research. 04 2024.
doi   link   bibtex  
Experimental capture of miRNA targetomes: disease-specific 3'UTR library-based miRNA targetomics for Parkinson's disease. Hart, M.; Kern, F.; Fecher-Trost, C.; Krammes, L.; Aparicio, E.; Engel, A.; Hirsch, P.; Wagner, V.; Keller, V.; Schmartz, G.; Rheinheimer, S.; Diener, C.; Fischer, U.; Mayer, J.; Meyer, M.; Flockerzi, V.; Keller, A.; and Meese, E. Experimental & molecular medicine, 56. 04 2024.
doi   link   bibtex  
SRF transcriptionally regulates the oligodendrocyte cytoskeleton during CNS myelination. Iram, T.; Garcia, M.; Amand, J.; Kaur, A.; Atkins, M.; Iyer, M.; Lam, M.; Ambiel, N.; Jorgens, D.; Keller, A.; Wyss-Coray, T.; Kern, F.; and Zuchero, J Proceedings of the National Academy of Sciences of the United States of America, 121: e2307250121. 03 2024.
doi   link   bibtex  
  2023 (17)
The miRNA–target interactions: An underestimated intricacy. Diener, C.; Keller, A.; and Meese, E. Nucleic Acids Research, 52. 11 2023.
doi   link   bibtex  
ABC-HuMi: the Atlas of Biosynthetic Gene Clusters in the Human Microbiome. Hirsch, P.; Tagirdzhanov, A.; Kushnareva, A.; Olkhovskii, I.; Graf, S.; Schmartz, G.; Hegemann, J.; Bozhueyuek, K.; Müller, R.; Keller, A.; and Gurevich, A. Nucleic Acids Research, 52. 11 2023.
ABC-HuMi: the Atlas of Biosynthetic Gene Clusters in the Human Microbiome [link]Paper   doi   link   bibtex   abstract  
ZEBRA: a hierarchically integrated gene expression atlas of the murine and human brain at single-cell resolution. Flotho, M.; Amand, J.; Hirsch, P.; Grandke, F.; Wyss-Coray, T.; Keller, A.; and Kern, F. Nucleic acids research, 52. 11 2023.
ZEBRA: a hierarchically integrated gene expression atlas of the murine and human brain at single-cell resolution [link]Paper   doi   link   bibtex   abstract  
The miRNA–target interactions: An underestimated intricacy. Diener, C.; Keller, A.; and Meese, E. Nucleic Acids Research. 11 2023.
The miRNA–target interactions: An underestimated intricacy [link]Paper   doi   link   bibtex   abstract  
Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing. Henn, D.; Zhao, D.; Sivaraj, D.; Trotsyuk, A.; Bonham, C.; Fischer, K.; Kehl, T.; Fehlmann, T.; Greco, A.; Kussie, H.; Illouz, S.; Padmanabhan, J.; Barrera, J.; Kneser, U.; Lenhof, H.; Januszyk, M.; Levi, B.; Keller, A.; Longaker, M.; and Gurtner, G. Nature Communications, 14. 08 2023.
Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing [link]Paper   doi   link   bibtex   abstract  
Atlas of the aging mouse brain reveals white matter as vulnerable foci. Hahn, O.; Foltz, A.; Atkins, M.; Kedir, B.; Moran Losada, P.; Guldner, I.; Munson, C.; Kern, F.; Pálovics, R.; Lu, N.; Zhang, H.; Kaur, A.; Hull, J.; Huguenard, J.; Groenke, S.; Lehallier, B.; Partridge, L.; Keller, A.; and Wyss-Coray, T. Cell, 186. 08 2023.
Atlas of the aging mouse brain reveals white matter as vulnerable foci [link]Paper   doi   link   bibtex   abstract  
Ageing-associated small RNA cargo of extracellular vesicles. Kern, F.; Kuhn, T.; Ludwig, N.; Simon, M.; Gröger, L.; Fabis, N.; Aparicio-Puerta, E.; Salhab, A.; Fehlmann, T.; Hahn, O.; Engel, A.; Wagner, V.; Koch, M.; Winek, K.; Soreq, H.; Nazarenko, I.; Fuhrmann, G.; Wyss-Coray, T.; Meese, E.; and Keller, A. RNA biology, 20: 482-494. 07 2023.
Ageing-associated small RNA cargo of extracellular vesicles [link]Paper   doi   link   bibtex   abstract  
Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation. Herppich, S.; Hönicke, L.; Kern, F.; Kruse, F.; Smout, J.; Greweling‐Pils, M.; Geffers, R.; Burton, O.; Liston, A.; Keller, A.; Floess, S.; and Huehn, J. European Journal of Immunology. 06 2023.
Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation [link]Paper   doi   link   bibtex   abstract  
miEAA 2023: updates, new functional microRNA sets and improved enrichment visualizations. Aparicio-Puerta, E.; Hirsch, P.; Schmartz, G.; Kern, F.; Fehlmann, T.; and Keller, A. Nucleic Acids Research. 05 2023.
miEAA 2023: updates, new functional microRNA sets and improved enrichment visualizations [link]Paper   doi   link   bibtex   abstract   3 downloads  
The Effect of a Planetary Health Diet on the Human Gut Microbiome: A Descriptive Analysis. Rehner, J.; Schmartz, G.; Kramer, T.; Keller, V.; Keller, A.; and Becker, S. L. Nutrients, 15: 1924. 04 2023.
The Effect of a Planetary Health Diet on the Human Gut Microbiome: A Descriptive Analysis [link]Paper   doi   link   bibtex   abstract   2 downloads  
Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues. Wagner, V.; Kern, F.; Hahn, O.; Schaum, N.; Ludwig, N.; Fehlmann, T.; Engel, A.; Henn, D.; Rishik, S.; Isakova, A.; Tan, M.; Sit, R.; Neff, N.; Hart, M.; Meese, E.; Quake, S.; Wyss-Coray, T.; and Keller, A. Nature Biotechnology,1-10. 04 2023.
Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues [link]Paper   doi   link   bibtex   abstract  
Occurrence, resistance patterns and management of carbapenemase-producing bacteria in war-wounded refugees from Ukraine. Berger, F.; Schmartz, G.; Fritz, T.; Veith, N.; Alhussein, F.; Roth, S.; Schneitler, S.; Gilcher, T.; Gärtner, B.; Pirpilashvili, V.; Pohlemann, T.; Keller, A.; Rehner, J.; and Becker, S. L. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 132. 04 2023.
Occurrence, resistance patterns and management of carbapenemase-producing bacteria in war-wounded refugees from Ukraine [link]Paper   doi   link   bibtex   abstract  
miR-34a-5p as molecular hub of pathomechanisms in Huntington’s disease. Hart, M.; Diener, C.; Lunkes, L.; Rheinheimer, S.; Krammes, L.; Keller, A.; and Meese, E. Molecular Medicine, 29. 04 2023.
miR-34a-5p as molecular hub of pathomechanisms in Huntington’s disease [link]Paper   doi   link   bibtex   abstract  
isomiRdb: microRNA expression at isoform resolution. Aparicio-Puerta, E.; Hirsch, P.; Schmartz, G.; Fehlmann, T.; Keller, V.; Engel, A.; Kern, F.; Hackenberg, M.; and Keller, A. Nucleic acids research, 51. 01 2023.
isomiRdb: microRNA expression at isoform resolution [link]Paper   doi   link   bibtex   abstract  
Time-resolved RNA signatures of CD4+ T cells in Parkinson’s disease. Diener, C.; Hart, M.; Kehl, T.; Becker-Dorison, A.; Tänzer, T.; Schub, D.; Krammes, L.; Sester, M.; Keller, A.; Unger, M.; Walch-Rückheim, B.; Lenhof, H.; and Meese, E. Cell Death Discovery, 9: 18. 01 2023.
Time-resolved RNA signatures of CD4+ T cells in Parkinson’s disease [link]Paper   doi   link   bibtex   abstract   1 download  
Artificial-intelligence-based decision support tools for the differential diagnosis of colitis. Guimarães, P.; Finkler, H.; Reichert, M.; Zimmer, V.; Gruenhage, F.; Krawczyk, M.; Lammert, F.; Keller, A.; and Casper, M. European journal of clinical investigation, 53: e13960. 01 2023.
Artificial-intelligence-based decision support tools for the differential diagnosis of colitis [link]Paper   doi   link   bibtex   abstract  
Outside the limit: questioning the distance restrictions for cooperative miRNA binding sites. Diener, C.; Hart, M.; Fecher-Trost, C.; Knittel, J.; Rheinheimer, S.; Meyer, M.; Mayer, J.; Flockerzi, V.; Keller, A.; and Meese, E. Cellular & Molecular Biology Letters, 28. 01 2023.
Outside the limit: questioning the distance restrictions for cooperative miRNA binding sites [link]Paper   doi   link   bibtex   abstract  
  2022 (15)
Dynamic and static circulating cancer microRNA biomarkers – a validation study. Abu-Halima, M.; Keller, A.; Becker, L.; Fischer, U.; Engel, A.; Ludwig, N.; Kern, F.; Rounge, T.; Langseth, H.; Meese, E.; and Keller, V. RNA Biology, 20: 1-9. 12 2022.
Dynamic and static circulating cancer microRNA biomarkers – a validation study [link]Paper   doi   link   bibtex   abstract  
NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart. Müller, M.; Eghbalian, R.; Boeckel, J.; Frese, K.; Haas, J.; Kayvanpour, E.; Sedaghat-Hamedani, F.; Lackner, M.; Tugrul, O.; Ruppert, T.; Tappu, R.; Bordalo, D.; Kneuer, J.; Piekarek, A.; Herch, S.; Schudy, S.; Keller, A.; Grammes, N.; Bischof, C.; and Meder, B. Nature Communications, 13: 6209. 10 2022.
NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart [link]Paper   doi   link   bibtex   abstract  
Multi-omics assessment of dilated cardiomyopathy using non-negative matrix factorization. Tappu, R.; Haas, J.; Lehmann, D.; Sedaghat-Hamedani, F.; Kayvanpour, E.; Keller, A.; Katus, H.; Frey, N.; and Meder, B. PLOS ONE, 17: e0272093. 08 2022.
Multi-omics assessment of dilated cardiomyopathy using non-negative matrix factorization [link]Paper   doi   link   bibtex   abstract  
Systematic cross-biospecimen evaluation of DNA extraction kits for long- and short-read multi-metagenomic sequencing studies. Rehner, J.; Schmartz , G. P.; Groeger, L.; Dastbaz, J.; Ludwig, N.; Hannig, M.; Rupf, S.; Seitz, B.; Flockerzi, E.; Berger, T.; Reichert, M. C.; Krawczyk, M.; Meese, E.; Herr, C.; Bals, R.; Becker, S. L.; Keller, A.; and Müller, R. Genomics, Proteomics & Bioinformatics. 06 2022.
Systematic cross-biospecimen evaluation of DNA extraction kits for long- and short-read multi-metagenomic sequencing studies [link]Paper   doi   link   bibtex   abstract   3 downloads  
Forecasting football injuries by combining screening, monitoring and machine learning. Hecksteden, A.; Schmartz, G. P.; Egyptien, Y.; Aus der Fünten, K.; Keller, A.; and Meyer, T. Science and Medicine in Football, 0(0): 1-15. 06 2022. PMID: 35757889
Forecasting football injuries by combining screening, monitoring and machine learning [link]Paper   doi   link   bibtex   abstract   2 downloads  
Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17. Iram, T.; Kern, F.; Kaur, A.; Myneni, S.; Morningstar, A. R.; Shin, H.; Garcia, M. A.; Yerra, L.; Palovics, R.; Yang, A. C.; Hahn, O.; Lu, N.; Shuken, S. R.; Haney, M. S.; Lehallier, B.; Iyer, M.; Luo, J.; Zetterberg, H.; Keller, A.; Zuchero, J. B.; and Wyss-Coray, T. Nature. 05 2022.
Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17 [link]Paper   doi   link   bibtex   abstract   4 downloads  
sRNAbench and sRNAtoolbox 2022 update: accurate miRNA and sncRNA profiling for model and non-model organisms. Aparicio-Puerta, E.; Gómez-Martín, C.; Giannoukakos, S.; Medina, J.; Scheepbouwer, C.; García-Moreno, A.; Carmona-Saez, P.; Fromm, B.; Pegtel, M.; Keller, A.; Marchal, J.; and Hackenberg, M. Nucleic Acids Research, 50(W1): W710-W717. 05 2022.
sRNAbench and sRNAtoolbox 2022 update: accurate miRNA and sncRNA profiling for model and non-model organisms [link]Paper   doi   link   bibtex   abstract   1 download  
Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting. Chen, K.; Henn, D.; Januszyk, M.; Barrera, J. A.; Noishiki, C.; Bonham, C. A.; Griffin, M.; Tevlin, R.; Carlomagno, T.; Shannon, T.; Fehlmann, T.; Trotsyuk, A. A.; Padmanabhan, J.; Sivaraj, D.; Perrault, D. P.; Zamaleeva, A. I.; Mays, C. J.; Greco, A. H.; Kwon, S. H.; Leeolou, M. C.; Huskins, S. L.; Steele, S. R.; Fischer, K. S.; Kussie, H. C.; Mittal, S.; Mermin-Bunnell, A. M.; Deleon, N. M. D.; Lavin, C.; Keller, A.; Longaker, M. T.; and Gurtner, G. C. Science Translational Medicine, 14(645): eabj9152. 05 2022.
Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting [link]Paper   doi   link   bibtex   abstract   1 download  
BusyBee Web: towards comprehensive and differential composition-based metagenomic binning. Schmartz, G. P; Hirsch, P.; Amand, J.; Dastbaz, J.; Fehlmann, T.; Kern, F.; Müller, R.; and Keller, A. Nucleic Acids Research. 04 2022.
BusyBee Web: towards comprehensive and differential composition-based metagenomic binning [link]Paper   doi   link   bibtex   abstract   1 download  
Ischemic Stroke–A Scientometric Analysis. Millenaar, D.; Ragoschke-Schumm, A.; Fehlmann, T.; Raible, M.; Lochner, P.; Böhm, M.; Fassbender, K.; Keller, A.; Mahfoud, F.; and Ukena, C. Frontiers in Neurology, 13: 893121. 04 2022.
Ischemic Stroke–A Scientometric Analysis [link]Paper   doi   link   bibtex   abstract  
A Temporary Pause in the Replication Licensing Restriction Leads to Rereplication during Early Human Cell Differentiation. Minet, M.; Abu-Halima, M.; Du, Y.; Doerr, J.; Isted, C.; Ludwig, N.; Keller, A.; Meese, E.; and Fischer, U. Cells. 03 2022.
A Temporary Pause in the Replication Licensing Restriction Leads to Rereplication during Early Human Cell Differentiation [link]Paper   doi   link   bibtex   abstract   1 download  
Emerging concepts of miRNA therapeutics: from cells to clinic. Diener, C.; Keller, A.; and Meese, E. Trends in Genetics. 03 2022.
Emerging concepts of miRNA therapeutics: from cells to clinic [link]Paper   doi   link   bibtex   abstract   5 downloads  
Molecular hallmarks of heterochronic parabiosis at single-cell resolution. Pálovics, R.; Keller, A.; Schaum, N.; Tan, W.; Fehlmann, T.; Borja, M.; Kern, F.; Bonanno, L.; Calcuttawala, K.; Webber, J.; Mcgeever, A.; Consortium, T. T. M.; Luo, J.; Pisco, A. O.; Karkanias, J.; Neff, N. F.; Darmanis, S.; Quake, S. R.; and Wyss-Coray, T. Nature, 603: 1-6. 03 2022.
Molecular hallmarks of heterochronic parabiosis at single-cell resolution [link]Paper   doi   link   bibtex   abstract   2 downloads  
A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk. Yang, A.; Vest, R.; Kern, F.; Lee, D.; Agam, M.; Maat, C.; Moran Losada, P.; Chen, M.; Schaum, N.; Khoury, N.; Toland, A.; Calcuttawala, K.; Shin, H.; Pálovics, R.; Shin, A.; Wang, E.; Luo, J.; Gate, D.; Schulz-Schaeffer, W.; Chu, P.; Siegenthaler, J. A.; McNerney, M. W.; Keller, A.; and Wyss-Coray, T. Nature, 603: 1-8. 02 2022.
A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk [link]Paper   doi   link   bibtex   abstract  
Detailed Transcriptional Landscape of Peripheral Blood Points to Increased Neutrophil Activation in Treatment-Naïve Inflammatory Bowel Disease. Juzenas, S.; Hübenthal, M.; Lindqvist, C. M.; Kruse, R.; Steiert, T. A.; Degenhardt, F.; Schulte, D.; Nikolaus, S.; Zeissig, S.; Bergemalm, D.; Almer, S.; Hjortswang, H.; Bresso, F.; Group, S. I. W.; Strüning, N.; Kupcinskas, J.; Keller, A.; Lieb, W.; Rosenstiel, P.; Schreiber, S.; D’Amato, M.; Halfvarson, J.; Hemmrich-Stanisak, G.; and Franke, A. Journal of Crohn's and Colitis. 01 2022. jjac003
Detailed Transcriptional Landscape of Peripheral Blood Points to Increased Neutrophil Activation in Treatment-Naïve Inflammatory Bowel Disease [link]Paper   doi   link   bibtex   abstract   2 downloads  
  2021 (23)
Effects of Resistant Starch on Symptoms, Fecal Markers and Gut Microbiota in Parkinson’s Disease – the RESISTA-PD Trial. Becker, A.; Schmartz, G.; Gröger, L.; Grammes, N.; Galata, V.; Philippeit, H.; Weiland, J.; Ludwig, N.; Meese, E.; Tierling, S.; Walter, J.; Schwiertz, A.; Spiegel, J.; Wagenpfeil, G.; Faßbender, K.; Keller, A.; and Unger, M. Genomics, Proteomics & Bioinformatics. 11 2021.
doi   link   bibtex   abstract   2 downloads  
PLSDB: advancing a comprehensive database of bacterial plasmids. Schmartz, G.; Hartung, A.; Hirsch, P.; Kern, F.; Fehlmann, T.; Müller, R.; and Keller, A. Nucleic Acids Research, 50. 11 2021.
doi   link   bibtex   abstract   1 download  
Controlling my genome with my smartphone: first clinical experiences of the PROMISE system. Amr, A.; Hinderer, M.; Griebel, L.; Deuber, D.; Egger, C.; Sedaghat-Hamedani, F.; Kayvanpour, E.; Huhn, D.; Haas, J.; Frese, K.; Schweig, M.; Marnau, N.; Krämer, A.; Durand, C.; Battke, F.; Prokosch, H.; Backes, M.; Keller, A.; Schröder, D.; Katus, H. A.; Frey, N.; and Meder, B. Clinical Research in Cardiology,1-13. 10 2021.
doi   link   bibtex   abstract   2 downloads  
Sex Differences in Cardiovascular Research: A Scientometric Analysis. Millenaar, D.; Dillmann, M.; Fehlmann, T.; Flohr, A.; Mehran, R.; Al-Lamee, R.; Lauder, L.; Ukena, C.; Böhm, M.; Keller, A.; and Mahfoud, F. Journal of the American Heart Association. 10 2021.
doi   link   bibtex   abstract  
miRNATissueAtlas2: an update to the human miRNA tissue atlas. Keller, A.; Gröger, L.; Tschernig, T.; Solomon, J.; Laham, O.; Schaum, N.; Wagner, V.; Kern, F.; Schmartz, G.; Li, Y.; Borcherding, A.; Meier, C.; Wyss-Coray, T.; Meese, E.; Fehlmann, T.; and Ludwig, N. Nucleic Acids Research, 50. 09 2021.
doi   link   bibtex   abstract  
GeneTrail: A Framework for the Analysis of High-Throughput Profiles. Gerstner, N.; Kehl, T.; Lenhof, K.; Eckhart, L.; Schneider, L.; Stöckel, D.; Backes, C.; Meese, E.; Keller, A.; and Lenhof, H. Frontiers in Molecular Biosciences, 8. 09 2021.
doi   link   bibtex   abstract   2 downloads  
Distinct Patterns of Blood Cytokines Beyond a Cytokine Storm Predict Mortality in COVID-19. Herr, C.; Mang, S.; Mozafari, B.; Guenther, K.; Speer, T.; Seibert, M.; Srikakulam, S. K.; Beisswenger, C.; Ritzmann, F.; Keller, A.; Müller, R.; Smola, S.; Eisinger, D.; Zemlin, M.; Danziger, G.; Volk, T.; Hörsch, S.; Krawczyk, M.; Lammert, F.; Adams, T.; Wagenpfeil, G.; Kindermann, M.; Marcu, C.; Ataya, Z. W. D.; Mittag, M.; Schwarzkopf, K.; Custodis, F.; Grandt, D.; Schaefer, H.; Eltges, K.; Lepper, P. M; and Bals, R. Journal of Inflammation Research, Volume 14: 4651-4667. 09 2021.
doi   link   bibtex   abstract  
Disrupting biological sensors of force promotes tissue regeneration in large organisms. Chen, K.; Kwon, S.; Henn, D.; Kuehlmann, B.; Tevlin, R.; Bonham, C.; Griffin, M.; Trotsyuk, A.; Borrelli, M.; Noishiki, C.; Padmanabhan, J.; Barrera, J.; Maan, Z.; Dohi, T.; Mays, C.; Greco, A.; Sivaraj, D.; Lin, J.; Fehlmann, T.; Mermin-Bunnell, A. M.; Mittal, S.; Hu, M. S.; Zamaleeva, A. I.; Keller, A.; Rajadas, J.; Longaker, M. T.; Januszyk, M.; and Gurtner, G. Nature Communications, 12. 09 2021.
doi   link   bibtex   abstract  
Towards the sustainable discovery and development of new antibiotics. Miethke, M.; Pieroni, M.; Weber, T.; Brönstrup, M.; Hammann, P.; Halby, L.; Arimondo, P.; Glaser, P.; Aigle, B.; Bode, H.; Moreira, R.; Li, Y.; Luzhetskyy, A.; Medema, M.; Pernodet, J.; Stadler, M.; Tormo, J.; Genilloud, O.; Truman, A.; Weissman, K. J.; Takano, E.; Sabatini, S.; Stegmann, E.; Brötz-Oesterhelt, H.; Wohlleben, W.; Seemann, M.; Empting, M.; Hirsch, A. K. H.; Loretz, B.; Lehr, C.; Titz, A.; Herrmann, J.; Jaeger, T.; Alt, S.; Hesterkamp, T.; Winterhalter, M.; Schiefer, A.; Pfarr, K.; Hoerauf, A.; Graz, H.; Graz, M.; Lindvall, M.; Ramurthy, S.; Karlén, A.; Dongen, M. v.; Petkovic, H.; Keller, A.; Peyrane, F.; Donadio, S.; Fraisse, L.; Piddock, L. J. V.; Gilbert, I. H.; Moser, H. E.; and Müller, R. Nature Reviews Chemistry,1-24. 08 2021.
doi   link   bibtex   abstract  
Single-cell microRNA sequencing method comparison and application to cell lines and circulating lung tumor cells. Hücker, S. M.; Fehlmann, T.; Werno, C.; Weidele, K.; Lüke, F.; Schlenska-Lange, A.; Klein, C. A.; Keller, A.; and Kirsch, S. Nature Communications. 07 2021.
Single-cell microRNA sequencing method comparison and application to cell lines and circulating lung tumor cells [link]Paper   doi   link   bibtex   abstract   1 download  
Differential degradation of RNA species by autophagy related pathways in Arabidopsis. Hickl, D.; Drews, F.; Girke, C.; Zimmer, D.; Mühlhaus, T.; Hauth, J.; Nordström, K.; Trentmann, O.; Neuhaus, E.; Scheuring, D.; Fehlmann, T.; Keller, A.; Martin, S.; and Möhlmann, T. Journal of experimental botany. 07 2021.
Differential degradation of RNA species by autophagy related pathways in Arabidopsis [link]Paper   doi   link   bibtex   abstract  
Characterization of micro-RNA in women with different ovarian reserve. Abu-Halima, M.; Becker, L.; Ayesh, B.; Baus, S.; Hamza, A.; Fischer, U.; Hammadeh, M. E.; Keller, A.; and Meese, E. Scientific Reports,13351. 06 2021.
Characterization of micro-RNA in women with different ovarian reserve [link]Paper   doi   link   bibtex   abstract  
hsa-miR-374b-5p regulates expression of the gene U2AF homology motif (UHM) kinase 1. Mueller, R.; Bajric, D.; Keceli, G.; Keller, A.; Dommisch, H.; Sharawy, A.; and Schaefer, A. Journal of Periodontal Research. 06 2021.
hsa-miR-374b-5p regulates expression of the gene U2AF homology motif (UHM) kinase 1 [link]Paper   doi   link   bibtex   abstract   2 downloads  
Dysregulation of brain and choroid plexus cell types in severe COVID-19. Yang, A.; Kern, F.; Moran Losada, P.; Agam, M.; Maat, C.; Schmartz, G.; Fehlmann, T.; Stein, J.; Schaum, N.; Lee, D.; Calcuttawala, K.; Vest, R.; Berdnik, D.; Lu, N.; Hahn, O.; Gate, D.; McNerney, M.; Channappa, D.; Cobos, I.; Ludwig, N.; Schulz-Schaeffer, W. J.; Keller, A.; and Wyss-Coray, T. Nature. 06 2021.
Dysregulation of brain and choroid plexus cell types in severe COVID-19 [link]Paper   doi   link   bibtex   3 downloads  
Deep-learning based detection of eosinophilic esophagitis. Guimarães, P.; Keller, A.; Fehlmann, T.; Lammert, F.; and Casper, M. Endoscopy. 05 2021.
Deep-learning based detection of eosinophilic esophagitis [link]Paper   doi   link   bibtex   abstract   4 downloads  
Aviator: a web service for monitoring the availability of web services. Fehlmann, T.; Kern, F.; Hirsch, P.; Steinhaus, R.; Seelow, D.; and Keller, A. Nucleic Acids Research. 05 2021.
Aviator: a web service for monitoring the availability of web services [link]Paper   doi   link   bibtex   abstract  
Swarm Learning for decentralized and confidential clinical machine learning. Warnat-Herresthal, S.; Schultze, H.; Shastry, K.; Manamohan, S.; Mukherjee, S.; Garg, V.; Sarveswara, R.; Händler, K.; Pickkers, P.; Aziz, N. A.; Ktena, S.; Tran, F.; Bitzer, M.; Ossowski, S.; Casadei, N.; Herr, C.; Petersheim, D.; Behrends, U.; Kern, F.; Fehlmann, T.; Schommers, P.; Lehmann, C.; Augustin, M.; Rybniker, J.; Altmüller, J.; Mishra, N.; Bernardes, J. P.; Krämer, B.; Bonaguro, L.; Schulte-Schrepping, J.; Domenico, E. D.; Siever, C.; Kraut, M.; Desai, M.; Monnet, B.; Saridaki, M.; Siegel, C. M.; Drews, A.; Nuesch-Germano, M.; Theis, H.; Heyckendorf, J.; Schreiber, S.; Kim-Hellmuth, S.; (COVAS), C. A. S.; Nattermann, J.; Skowasch, D.; Kurth, I.; Keller, A.; Bals, R.; Nürnberg, P.; Rieß, O.; Rosenstiel, P.; Netea, M. G.; Theis, F.; Mukherjee, S.; Backes, M.; Aschenbrenner, A. C.; Ulas, T.; , D. C. O. I. (.; Breteler, M. M. B.; Giamarellos-Bourboulis, E. J.; Kox, M.; Becker, M.; Cheran, S.; Woodacre, M. S.; Goh, E. L.; and Schultze, J. Nature. 05 2021.
Swarm Learning for decentralized and confidential clinical machine learning [link]Paper   doi   link   bibtex   abstract   2 downloads  
miRTargetLink 2.0—interactive miRNA target gene and target pathway networks. Kern, F.; Aparicio-Puerta, E.; Li, Y.; Fehlmann, T.; Kehl, T.; Wagner, V.; Ray, K.; Ludwig, N.; Lenhof, H.; Meese, E.; and Keller, A. Nucleic Acids Research. 05 2021.
miRTargetLink 2.0—interactive miRNA target gene and target pathway networks [link]Paper   doi   link   bibtex   abstract   4 downloads  
miRMaster 2.0: multi-species non-coding RNA sequencing analyses at scale. Fehlmann, T.; Kern, F.; Laham, O.; Backes, C.; Solomon, J.; Hirsch, P.; Volz, C.; Müller, R.; and Keller, A. Nucleic acids research. 04 2021.
miRMaster 2.0: multi-species non-coding RNA sequencing analyses at scale [link]Paper   doi   link   bibtex   abstract  
MicroRNA‐targeting in spermatogenesis: Over‐expressions of microRNA‐23a/b‐3p and its affected targeting of the genes ODF2 and UBQLN3 in spermatozoa of patients with oligoasthenozoospermia. Abu-Halima, M.; Belkacemi, A.; Ayesh, B.; Becker, L.; Sindiani, A.; Fischer, U.; Hammadeh, M. E.; Keller, A.; and Meese, E. Andrology. 03 2021.
MicroRNA‐targeting in spermatogenesis: Over‐expressions of microRNA‐23a/b‐3p and its affected targeting of the genes ODF2 and UBQLN3 in spermatozoa of patients with oligoasthenozoospermia [link]Paper   doi   link   bibtex   abstract  
Deep sequencing of sncRNAs reveals hallmarks and regulatory modules of the transcriptome during Parkinson’s disease progression. Kern, F.; Fehlmann, T.; Violich, I.; Alsop, E.; Hutchins, E.; Kahraman, M.; Grammes, N.; Guimarães, P.; Backes, C.; Poston, K.; Casey, B.; Balling, R.; Geffers, L.; Krüger, R.; Galasko, D.; Mollenhauer, B.; Meese, E.; Wyss-Coray, T.; Craig, D.; Keuren-Jensen, K. V.; and Keller, A. Nature Aging, 1: 309-322. 03 2021.
Deep sequencing of sncRNAs reveals hallmarks and regulatory modules of the transcriptome during Parkinson’s disease progression [link]Paper   doi   link   bibtex   abstract   5 downloads  
Energy Metabolites as Biomarkers in Ischemic and Dilated Cardiomyopathy. Haas, J.; Frese, K.; Sedaghat-Hamedani, F.; Kayvanpour, E.; Tappu, R.; Nietsch, R.; Tugrul, O.; Wisdom, M.; Dietrich, C.; Amr, A.; Weis, T.; Niederdränk, T.; Murphy, M.; Krieg, T.; Dörr, M.; Völker, U.; Fielitz, J.; Frey, N.; Felix, S. B.; Keller, A.; Katus, H. A.; and Meder, B. International Journal of Molecular Sciences, 22: 1999. 02 2021.
Energy Metabolites as Biomarkers in Ischemic and Dilated Cardiomyopathy [link]Paper   doi   link   bibtex   abstract  
MicroRNA-29b/c-3p Indicate Advanced Liver Fibrosis/Cirrhosis in Univentricular Heart Patients With and Without Fontan Palliation. Abu-Halima, M.; Meese, E.; Saleh, M.; Keller, A.; Abdul-Khaliq, H.; and Raedle-Hurst, T. Frontiers in Cardiovascular Medicine, 7: 619083. 01 2021.
MicroRNA-29b/c-3p Indicate Advanced Liver Fibrosis/Cirrhosis in Univentricular Heart Patients With and Without Fontan Palliation [link]Paper   doi   link   bibtex   abstract  
  2020 (29)
Encyclopedia of tools for the analysis of miRNA isoforms. Schmartz, G. P.; Kern, F.; Fehlmann, T.; Wagner, V.; Fromm, B.; and Keller, A. Briefings in Bioinformatics. 12 2020.
Encyclopedia of tools for the analysis of miRNA isoforms [link]Paper   doi   link   bibtex   abstract  
A multivariable miRNA signature delineates the systemic hemodynamic impact of arteriovenous shunt placement in a pilot study. Henn, D.; Abu-Halima, M.; Kahraman, M.; Falkner, F.; Fischer, K.; Barrera, J.; Chen, K.; Gurtner, G.; Keller, A.; Kneser, U.; Meese, E.; and Schmidt, V. Scientific Reports, 10. 12 2020.
doi   link   bibtex   abstract  
Research Output and International Cooperation Among Countries During the COVID-19 Pandemic: Scientometric Analysis. Grammes, N.; Millenaar, D.; Fehlmann, T.; Kern, F.; Böhm, M.; Mahfoud, F.; and Keller, A. J Med Internet Res. 12 2020.
Research Output and International Cooperation Among Countries During the COVID-19 Pandemic: Scientometric Analysis [link]Paper   doi   link   bibtex   abstract  
Validation of human microRNA target pathways enables evaluation of target prediction tools. Kern, F.; Krammes, L.; Danz, K.; Diener, C.; Kehl, T.; Küchler, O.; Fehlmann, T.; Kahraman, M.; Rheinheimer, S.; Aparicio-Puerta, E.; Wagner, S.; Ludwig, N.; Backes, C.; Lenhof, H.; von Briesen , H.; Hart, M.; Keller, A.; and Meese, E. Nucleic Acids Research. 12 2020.
Validation of human microRNA target pathways enables evaluation of target prediction tools [link]Paper   doi   link   bibtex   abstract  
CoolMPS: evaluation of antibody labeling based massively parallel non-coding RNA sequencing. Li, Y.; Fehlmann, T.; Borcherding, A.; Drmanac, S.; Liu, S.; Groeger, L.; Xu, C.; Callow, M.; Villarosa, C.; Jorjorian, A.; Kern, F.; Grammes, N.; Meese, E.; Jiang, H.; Drmanac, R.; Ludwig, N.; and Keller, A. Nucleic Acids Research. 12 2020.
CoolMPS: evaluation of antibody labeling based massively parallel non-coding RNA sequencing [link]Paper   doi   link   bibtex   abstract  
On the lifetime of bioinformatics web services. Kern, F.; Fehlmann, T.; and Keller, A. Nucleic Acids Research, 48(22): 12523-12533. 12 2020.
On the lifetime of bioinformatics web services [link]Paper   doi   link   bibtex   abstract  
CoolMPS for robust sequencing of single-nuclear RNAs captured by droplet-based method. Hahn, O.; Fehlmann, T.; Zhang, H.; Munson, C. N; Vest, R. T; Borcherding, A.; Liu, S.; Villarosa, C.; Drmanac, S.; Drmanac, R.; Keller, A.; and Wyss-Coray, T. Nucleic Acids Research. 12 2020.
CoolMPS for robust sequencing of single-nuclear RNAs captured by droplet-based method [link]Paper   doi   link   bibtex   abstract  
HumiR: Web Services, Tools and Databases for Exploring Human microRNA Data. Solomon, J.; Kern, F.; Fehlmann, T.; Meese, E.; and Keller, A. Biomolecules, 10. 12 2020.
doi   link   bibtex   abstract  
Common diseases alter the physiological age-related blood microRNA profile. Fehlmann, T.; Lehallier, B.; Schaum, N.; Hahn, O.; Kahraman, M.; Li, Y.; Grammes, N.; Geffers, L.; Backes, C.; Balling, R.; Kern, F.; Krüger, R.; Lammert, F.; Ludwig, N.; Meder, B.; Fromm, B.; Maetzler, W.; Berg, D.; Brockmann, K.; Deuschle, C.; von Thaler, A.; Eschweiler, G. W.; Milman, S.; Barziliai, N.; Reichert, M.; Wyss-Coray, T.; Meese, E.; and Keller, A. Nature Communications, 11. 11 2020.
doi   link   bibtex   abstract  
Wrinkle in the plan: miR-34a-5p impacts chemokine signaling by modulating CXCL10/CXCL11/CXCR3-axis in CD4+, CD8+ T cells, and M1 macrophages. Hart, M.; Nickl, L.; Walch-Rueckheim, B.; Krammes, L.; Rheinheimer, S.; Diener, C.; Taenzer, T.; Kehl, T.; Sester, M.; Lenhof, H.; Keller, A.; and Meese, E. Journal for ImmunoTherapy of Cancer, 8(2). 11 2020.
Wrinkle in the plan: miR-34a-5p impacts chemokine signaling by modulating CXCL10/CXCL11/CXCR3-axis in CD4+, CD8+ T cells, and M1 macrophages [link]Paper   doi   link   bibtex   abstract   1 download  
Quantitative and time-resolved miRNA pattern of early human T cell activation. Diener, C.; Hart, M.; Kehl, T.; Rheinheimer, S.; Ludwig, N.; Krammes, L.; Pawusch, S.; Lenhof, K.; Tänzer, T.; Schub, D.; Sester, M.; Walch-Rückheim, B.; Keller, A.; Lenhof, H.; and Meese, E. Nucleic Acids Research, 48(18): 10164-10183. 09 2020.
Quantitative and time-resolved miRNA pattern of early human T cell activation [pdf]Paper   doi   link   bibtex   abstract  
A mouse tissue atlas of small noncoding RNA. Isakova, A.; Fehlmann, T.; Keller, A.; and Quake, S. R. Proceedings of the National Academy of Sciences, 117(41): 25634–25645. 09 2020.
A mouse tissue atlas of small noncoding RNA [link]Paper   doi   link   bibtex   abstract  
Research in Atrial Fibrillation: A Scientometric Analysis Using the Novel Web Application SciPE. Millenaar, D.; Fehlmann, T.; Scholz, S.; Pavlicek, V.; Flohr, A.; Dillmann, M.; Böhm, M.; Keller, A.; Mahfoud, F.; and Ukena, C. JACC: Clinical Electrophysiology, 6(8): 1008 - 1018. 07 2020.
Research in Atrial Fibrillation: A Scientometric Analysis Using the Novel Web Application SciPE [link]Paper   doi   link   bibtex   abstract  
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse. Consortium, T. T. M. Nature. 07 2020.
doi   link   bibtex   abstract   1 download  
Ageing hallmarks exhibit organ-specific temporal signatures. Schaum, N.; Lehallier, B.; Hahn, O.; Pálovics, R.; Hosseinzadeh, S.; Lee, S. E.; Sit, R.; Lee, D. P.; Losada, P. M.; Zardeneta, M. E.; Fehlmann, T.; Webber, J. T.; McGeever, A.; Calcuttawala, K.; Zhang, H.; Berdnik, D.; Mathur, V.; Tan, W.; Zee, A.; Tan, M.; Consortium, T. T. M.; Pisco, A. O.; Karkanias, J.; Neff, N. F.; Keller, A.; Darmanis, S.; Quake, S. R.; and Wyss-Coray, T. Nature. 07 2020.
doi   link   bibtex   abstract   2 downloads  
Competitive learning suggests circulating miRNA profiles for cancers decades prior to diagnosis. Keller, A.; Fehlmann, T.; Backes, C.; Kern, F.; Gislefoss, R.; Langseth, H.; Rounge, T. B.; Ludwig, N.; and Meese, E. RNA Biology. 06 2020.
doi   link   bibtex   abstract   2 downloads  
Induction of the Endoplasmic-Reticulum-Stress Response: MicroRNA-34a Targeting of the IRE1α-Branch. Krammes, L.; Hart, M.; Rheinheimer, S.; Diener, C.; Menegatti, J.; Grässer, F.; Keller, A.; and Meese, E. Cells. 06 2020.
doi   link   bibtex   abstract  
Epigenetic Regulation of Alternative mRNA Splicing in Dilated Cardiomyopathy. Gi, W.; Haas, J.; Sedaghat-Hamedani, F.; Kayvanpour, E.; Tappu, R.; Lehmann, D. H.; Shirvani Samani, O.; Wisdom, M.; Keller, A.; Katus, H. A.; and Meder, B. Journal of Clinical Medicine. 05 2020.
doi   link   bibtex   abstract  
GeneTrail 3: advanced high-throughput enrichment analysis. Gerstner, N.; Kehl, T.; Lenhof, K.; Müller, A.; Mayer, C.; Eckhart, L.; Grammes, N. L.; Diener, C.; Hart, M.; Hahn, O.; Walter, J.; Wyss-Coray, T.; Meese, E.; Keller, A.; and Lenhof, H. Nucleic Acids Research. 05 2020.
doi   link   bibtex   abstract   1 download  
miEAA 2.0: integrating multi-species microRNA enrichment analysis and workflow management systems. Kern, F.; Fehlmann, T.; Solomon, J.; Schwed, L.; Grammes, N.; Backes, C.; Van Keuren-Jensen, K.; Craig, D. W.; Meese, E.; and Keller, A. Nucleic Acids Research. 05 2020.
doi   link   bibtex   abstract  
miRSwitch: detecting microRNA arm shift and switch events. Kern, F.; Amand, J.; Senatorov, I.; Isakova, A.; Backes, C.; Meese, E.; Keller, A.; and Fehlmann, T. Nucleic Acids Research. 05 2020.
doi   link   bibtex   abstract   2 downloads  
microRNA neural networks improve diagnosis of acute coronary syndrome (ACS). Kayvanpour, E.; Gi, W.; Sedaghat-Hamedani, F.; Lehmann, D. H.; Frese, K. S.; Haas, J.; Tappu, R.; Samani, O. S.; Nietsch, R.; Kahraman, M.; Fehlmann, T.; Müller-Hennessen, M.; Weis, T.; Giannitsis, E.; Niederdränk, T.; Keller, A.; Katus, H. A.; and Meder, B. Journal of Molecular and Cellular Cardiology. 04 2020.
doi   link   bibtex   abstract  
Quo vadis microRNAs?. Fromm, B.; Keller, A.; Yang, X.; Friedlander, M. R.; Peterson, K. J.; and Griffiths-Jones, S. Trends in Genetics. 04 2020.
doi   link   bibtex   abstract   2 downloads  
Insights from circulating microRNAs in cardiovascular entities in turner syndrome patients. Abu-Halima, M.; Oberhoffer, F.; Abd el Rahman, M.; Jung, A.; Zemlin, M.; Rohrer, T.; Kahraman, M.; Keller, A.; Meese, E.; and Abdul-Khaliq, H. PLOS ONE. 04 2020.
doi   link   bibtex   abstract  
Untersuchung von miRNAs mithilfe getrockneter Blutstropfen. Diener, C.; Keller, A.; and Meese, E. BIOspektrum,174-176. 03 2020.
doi   link   bibtex   abstract   1 download  
MicroRNAs in combined spent culture media and sperm are associated with embryo quality and pregnancy outcome. Abu-Halima, M.; Khaizaran, Z. A.; Ayesh, B. M.; Fischer, U.; Khaizaran, S. A.; Al-Battah, F.; Hammadeh, M.; Keller, A.; and Meese, E. Fertility and Sterility. 03 2020.
doi   link   bibtex   abstract  
Cigarette smoke and electronic cigarettes differentially activate bronchial epithelial cells. Herr, C.; Tsitouras, K.; Niederstraßer, J.; Backes, C.; Beisswenger, C.; Dong, L.; Guillot, L.; Keller, A.; and Bals, R. BioMed Central,67. 03 2020.
doi   link   bibtex   abstract   1 download  
Evaluating the Use of Circulating MicroRNA Profiles for Lung Cancer Detection in Symptomatic Patients. Fehlmann, T.; Kahraman, M.; Ludwig, N.; Backes, C.; Galata, V.; Keller, V.; Geffers, L.; Mercaldo, N.; Hornung, D.; Weis, T.; Kayvanpour, E.; Abu-Halima, M.; Deuschle, C.; Schulte, C.; Suenkel, U.; von Thaler, A.; Maetzler, W.; Herr, C.; Fähndrich, S.; Vogelmeier, C.; Guimaraes, P.; Hecksteden, A.; Meyer, T.; Metzger, F.; Diener, C.; Deutscher, S.; Abdul-Khaliq, H.; Stehle, I.; Haeusler, S.; Meiser, A.; Groesdonk, H. V; Volk, T.; Lenhof, H.; Katus, H.; Balling, R.; Meder, B.; Kruger, R.; Huwer, H.; Bals, R.; Meese, E.; and Keller, A. JAMA Oncology. 03 2020.
doi   link   bibtex   abstract   8 downloads  
Long-term unsupervised mobility assessment in movement disorders. Warmerdam, E.; Hausdorff, J. M; Atrsaei, A.; Zhou, Y.; Mirelman, A.; Aminian, K.; Espay, A. J; Hansen, C.; Evers, L. J W; Keller, A.; Lamoth, C.; Pilotto, A.; Rochester, L.; Schmidt, G.; Bloem, B. R; and Maetzler, W. The Lancet Neurology,1474-4422. 02 2020.
doi   link   bibtex   abstract   1 download  
  2019 (42)
MicroRNA signature in spermatozoa and seminal plasma of proven fertile men and in testicular tissue of men with obstructive azoospermia. Abu-Halima, M.; Galata, V.; Backes, C.; Keller, A.; Hammadeh, M.; and Meese, E. Andrologia,e13503. 2019.
doi   link   bibtex   abstract  
A 10-year prediagnostic follow-up study shows that serum RNA signals are highly dynamic in lung carcinogenesis. Umu, S. U.; Langseth, H.; Keller, A.; Meese, E.; Helland, A.; Lyle, R.; and Rounge, T. B Molecular oncology,235-247. 2019.
doi   link   bibtex   abstract  
Insights into Male Androgenetic Alopecia: Differential Gene Expression Profiling of Plucked Hair Follicles and Integration with Genetic Data. Hochfeld, L. M; Keller, A.; Anhalt, T.; Fricker, N.; Nöthen, M. M; and Heilmann-Heimbach, S. Journal of Investigative Dermatology, 139: 235-238. January 2019.
doi   link   bibtex   1 download  
Sequencing-based hematopoietic miRNA landscape reveals common and distinct features of autoimmune inflammatory phenotypes. Juzenas, S; Hübenthal, M; Zeissig, S; Strüning, N; Keller, A; Schulte, D; D'Amato, M; Lindqvist, C. M.; Kupcinskas, J; Schreiber, S; Halfvarson, J.; Hemmrich-Stanisak, G; and Franke, A Journal of Crohn's & Colitis, 13: S614-S614. 2019.
doi   link   bibtex   abstract   1 download  
Clinical Resistome Screening of 1,110 Escherichia coli Isolates Efficiently Recovers Diagnostically Relevant Antibiotic Resistance Biomarkers and Potential Novel Resistance Mechanisms. Volz, C.; Ramoni, J.; Beisken, S.; Galata, V.; Keller, A.; Plum, A.; Posch, A. E; and Müller, R. Frontiers in microbiology, 10: 1671. 2019.
doi   link   bibtex   abstract   3 downloads  
Large-scale validation of miRNAs by disease association, evolutionary conservation and pathway activity. Fehlmann, T.; Laufer, T.; Backes, C.; Kahramann, M.; Alles, J.; Fischer, U.; Minet, M.; Ludwig, N.; Kern, F.; Kehl, T.; Galata, V.; Düsterloh, A.; Schrörs, H.; Kohlhaas, J.; Bals, R.; Huwer, H.; Geffers, L.; Krüger, R.; Balling, R.; Lenhof, H.; Meese, E.; and Keller, A. RNA biology, 16: 93-103. January 2019.
doi   link   bibtex   abstract  
miR-34a: a new player in the regulation of T cell function by modulation of NF-κB signaling. Hart, M.; Walch-Rückheim, B.; Friedmann, K. S; Rheinheimer, S.; Tänzer, T.; Glombitza, B.; Sester, M.; Lenhof, H.; Hoth, M.; Schwarz, E. C; Keller, A.; and Meese, E. Cell death & disease, 10: 46. January 2019.
doi   link   bibtex   abstract  
Epstein-Barr Virus Infection of Cell Lines Derived from Diffuse Large B-Cell Lymphomas Alters MicroRNA Loading of the Ago2 Complex. Ayoubian, H.; Ludwig, N.; Fehlmann, T.; Menegatti, J.; Gröger, L.; Anastasiadou, E.; Trivedi, P.; Keller, A.; Meese, E.; and Grässer, F. A Journal of virology, 93: e01297-18. February 2019.
doi   link   bibtex   abstract  
3d cellular architecture affects microrna and protein cargo of extracellular vesicles. Rocha, S.; Carvalho, J.; Oliveira, P.; Voglstaetter, M.; Schvartz, D.; Thomsen, A. R; Walter, N.; Khanduri, R.; Sanchez, J.; Keller, A.; Oliveira, C.; and Nazarenko, I. Advanced Science, 6: 1800948. February 2019.
doi   link   bibtex   abstract  
MicroRNA profiling from dried blood samples. Diener, C.; Galata, V.; Keller, A.; and Meese, E. Critical reviews in clinical laboratory sciences, 56: 111-117. February 2019.
doi   link   bibtex   abstract  
Untargeted metabolomics by high resolution mass spectrometry coupled to normal and reversed phase liquid chromatography as a tool to study the in vitro biotransformation of new psychoactive substances. Manier, S. K; Keller, A.; Schäper, J.; and Meyer, M. R Scientific reports, 9: 2741. February 2019.
doi   link   bibtex   abstract  
An estimate of the total number of true human miRNAs. Alles, J.; Fehlmann, T.; Fischer, U.; Backes, C.; Galata, V.; Minet, M.; Hart, M.; Abu-Halima, M.; Grässer, F. A; Lenhof, H.; Keller, A.; and Meese, E. Nucleic acids research, 47: 3353-3364. March 2019.
doi   link   bibtex   abstract  
The role of TCF3 as potential master regulator in blastemal Wilms tumors. Kehl, T.; Schneider, L.; Kattler, K.; Stöckel, D.; Wegert, J.; Gerstner, N.; Ludwig, N.; Distler, U.; Tenzer, S.; Gessler, M.; Walter, J.; Keller, A.; Graf, N.; Meese, E.; and Lenhof, H. International journal of cancer, 144: 1432-1443. March 2019.
doi   link   bibtex   abstract  
The sncRNA Zoo: a repository for circulating small noncoding RNAs in animals. Fehlmann, T.; Backes, C.; Pirritano, M.; Laufer, T.; Galata, V.; Kern, F.; Kahraman, M.; Gasparoni, G.; Ludwig, N.; Lenhof, H.; Gregersen, H. A; Francke, R.; Meese, E.; Simon, M.; and Keller, A. Nucleic acids research, 47: 4431-4441. April 2019.
doi   link   bibtex   abstract  
ClinOmicsTrailbc: a visual analytics tool for breast cancer treatment stratification. Schneider, L.; Kehl, T.; Thedinga, K.; Grammes, N. L.; Backes, C.; Mohr, C.; Schubert, B.; Lenhof, K.; Gerstner, N.; Hartkopf, A. D.; Wallwiener, M.; Kohlbacher, O.; Keller, A.; Meese, E.; Graf, N.; and Lenhof, H. Bioinformatics,1367-4803. April 2019.
doi   link   bibtex   abstract  
Differential expression of miR-23a/b-3p and its target genes in male patients with subfertility. Abu-Halima, M.; Ayesh, B. M; Hart, M.; Alles, J.; Fischer, U.; Hammadeh, M.; Keller, A.; Huleihel, M.; and Meese, E. Fertility and sterility, 112: 241-242. May 2019.
doi   link   bibtex   abstract  
Spring is in the air: seasonal profiles indicate vernal change of miRNA activity. Ludwig, N.; Hecksteden, A.; Kahraman, M.; Fehlmann, T.; Laufer, T.; Kern, F.; Meyer, T.; Meese, E.; Keller, A.; and Backes, C. RNA biology, 16: 1034-1043. May 2019.
doi   link   bibtex   abstract  
Integrating Culture-based Antibiotic Resistance Profiles with Whole-genome Sequencing Data for 11,087 Clinical Isolates. Galata, V.; Laczny, C. C; Backes, C.; Hemmrich-Stanisak, G.; Schmolke, S.; Franke, A.; Meese, E.; Herrmann, M.; von Mueller, L.; Plum, A.; Mueller, R.; Stähler, C.; Posch, A. E; and Keller, A. Genomics, proteomics & bioinformatics, 17: 169-182. May 2019.
doi   link   bibtex   abstract  
Prospect and challenge of detecting dynamic gene copy number increases in stem cells by whole genome sequencing. Fischer, U.; Backes, C.; Fehlmann, T.; Galata, V.; Keller, A.; and Meese, E. Journal of Molecular Medicine, 97: 1099–1111. May 2019.
doi   link   bibtex   abstract  
Automated optimization of XCMS parameters for improved peak picking of liquid chromatography–mass spectrometry data using the coefficient of variation and parameter sweeping for untargeted metabolomics. Manier, S. K; Keller, A.; and Meyer, M. R Drug testing and analysis, 11: 752-761. June 2019.
doi   link   bibtex   abstract  
Proteomic Analysis of the Initial Oral Pellicle in Caries-Active and Caries-Free Individuals. Trautmann, S.; Barghash, A.; Fecher-Trost, C.; Schalkowsky, P.; Hannig, C.; Kirsch, J.; Rupf, S.; Keller, A.; Helms, V.; and Hannig, M. PROTEOMICS–Clinical Applications, 13: 1800143. July 2019.
doi   link   bibtex   abstract  
Profiling microRNA expression in murine bone healing and non-union formation: Role of miR-140 during the early stage of bone healing. Orth, M.; Scheuer, C.; Backes, C.; Keller, A.; Rollmann, M. F; Braun, B. J; Ludwig, N.; Meese, E.; Pohlemann, T.; Laschke, M. W; Menger, M. D; and Histing, T. PloS one, 14: e0218395. July 2019.
doi   link   bibtex   abstract  
Deep-learning based detection of gastric precancerous conditions. Guimaraes, P.; Keller, A.; Fehlmann, T.; Lammert, F.; and Casper, M. Gut,0017-5749. August 2019.
doi   link   bibtex   abstract  
Systematic assessment of blood-borne microRNAs highlights molecular profiles of endurance sport and carbohydrate uptake. Kern, F.; Ludwig, N.; Backes, C.; Maldener, E.; Fehlmann, T.; Suleymanov, A.; Meese, E.; Hecksteden, A.; Keller, A.; and Meyer, T. Cells, 8: 1045. September 2019.
doi   link   bibtex   abstract  
Deep-Learning basierter Bildanalyse-Algorithmus zur Erkennung der atrophischen Gastritis. Casper, M; Guimarães, P; Fehlmann, T; Keller, A; and Lammert, F Zeitschrift für Gastroenterologie, 57: KV 406. September 2019.
doi   link   bibtex   abstract  
Low miR-150-5p and miR-320b Expression Predicts Reduced Survival of COPD Patients. Keller, A.; Ludwig, N.; Fehlmann, T.; Kahraman, M.; Backes, C.; Kern, F.; Vogelmeier, C. F; Diener, C.; Fischer, U.; Biertz, F.; Herr, C.; Jörres, R. A; Lenhof, H.; Bals, R.; and Meese, E. Cells, 8: 1162. September 2019.
doi   link   bibtex   abstract  
MicroRNA-regulated pathways of flow-stimulated angiogenesis and vascular remodeling in vivo. Henn, D.; Abu-Halima, M.; Wermke, D.; Falkner, F.; Thomas, B.; Köpple, C.; Ludwig, N.; Schulte, M.; Brockmann, M. A; Kim, Y.; Sacks, J. M; Kneser, U.; Keller, A.; Meese, E.; and Schmidt, V. J Journal of translational medicine, 17: 22. 2019.
doi   link   bibtex   abstract  
The composition of the pulmonary microbiota in sarcoidosis–an observational study. Becker, A.; Vella, G.; Galata, V.; Rentz, K.; Beisswenger, C.; Herr, C.; Walter, J.; Tierling, S.; Slevogt, H.; Keller, A.; and Bals, R. Respiratory research, 20: 46. 2019.
doi   link   bibtex   abstract  
miR-34a as hub of T cell regulation networks. Hart, M.; Walch-Rückheim, B.; Krammes, L.; Kehl, T.; Rheinheimer, S.; Tänzer, T.; Glombitza, B.; Sester, M.; Lenhof, H.; Keller, A.; and Meese, E. Journal for immunotherapy of cancer, 7: 187. 2019.
doi   link   bibtex   abstract  
Limited Long-Term Impact of Insect Venom Immunotherapy on the Micro-RNA Landscape in Whole Blood. P., K.; M., K.; N., L.; P., S.; M., K.; M., R.; E., K.; B., P.; M., N.; N., B.; A., K.; E., M.; and MM., S. J Investig Allergol Clin Immunol., 29: 206-212. 2019.
doi   link   bibtex   abstract  
Machine Learning to Detect Alzheimer's Disease from Circulating Non-coding RNAs. Ludwig, N.; Fehlmann, T.; Kern, F.; Gogol, M.; Maetzler, W.; Deutscher, S.; Gurlit, S.; ClaudiaSchulte; Thaler, A.; Deuschle, C.; Metzger, F.; Berg, D.; Suenkel, U.; Keller, V.; Backes, C.; Lenhof, H.; Meese, E.; and Keller, A. Genomics, Proteomics & Bioinformatics, 17: 430-440. 2019.
doi   link   bibtex   abstract   1 download  
An 80,000-Piece Puzzle of Alzheimer's Disease. Iram, T.; Keller, A.; and Wyss-Coray, T. Immunity, 50: 1349-1351. 2019.
doi   link   bibtex   abstract  
Micro-RNA 150-5p predicts overt heart failure in patients with univentricular hearts. Masood, A.; Eckart, M.; Ali, S. M.; Andreas, K.; Hashim, A.; and Tanja, R. PLoS One, 14: e0223606. 2019.
doi   link   bibtex   abstract  
Contemporary scientometric analyses using a novel web application: the science performance evaluation (SciPE) approach. Scholz, S. S.; Dillmann, M.; Flohr, A.; Backes, C.; Fehlmann, T.; Millenaar, D.; Ukena, C.; Böhm, M.; Keller, A.; and Mahfoud, F. Clin Res Cardiol,1–9. 2019.
doi   link   bibtex   abstract  
miRPathDB 2.0: a novel release of the miRNA Pathway Dictionary Database. Kehl, T.; Kern, F.; Backes, C.; Fehlmann, T.; Stöckel, D.; Meese, E.; Lenhof, H.; and Keller, A. Nucleic Acids Research, 48: D142–D147. 2019.
doi   link   bibtex   abstract  
Undulating changes in human plasma proteome profiles across the lifespan. Lehallier, B.; Gate, D.; Schaum, N.; Nanasi, T.; Lee, S. E.; Yousef, H.; Losada, P. M.; Berdnik, D.; Keller, A.; Verghese, J.; Sathyan, S.; Franceschi, C.; Milman, S.; Barzilai, N.; and Wyss-Coray, T. Nature Medicine, 25: 1843-1850. 2019.
doi   link   bibtex   abstract  
Comparative Analysis of Biochemical Biases by Ligation- and Template-Switch-Based Small RNA Library Preparation Protocols. Meistertzheim, M.; Fehlmann, T.; Drews, F.; Pirritano, M.; Gasparoni, G.; Keller, A.; and Simon, M. Clinical Chemistry, 65: 1581-1591. 2019.
doi   link   bibtex   abstract  
What's the target: understanding two decades of in silico microRNA-target prediction. Kern, F.; Backes, C.; Hirsch, P.; Fehlmann, T.; Hart, M.; Meese, E.; and Keller, A. Briefings in Bioinformatics. 2019.
doi   link   bibtex   abstract  
Micro-RNA signatures in monozygotic twins discordant for congenital heart defects. Abu-Halima, M.; Weidinger, J.; Poryo, M.; Henn, D.; Keller, A.; Meese, E.; and Abdul-Khaliq, H. PLOS ONE, 14: 1-13. 2019.
doi   link   bibtex   abstract  
A 10 year prediagnostic followup study shows that serum RNA signals are highly dynamic in lung carcinogenesis. Umu, S. U.; Langseth, H.; Keller, A.; Meese, E.; Helland, Å.; Lyle, R.; and Rounge, T. B. Molecular Oncology. 2019.
doi   link   bibtex   abstract  
MicroRNA signature in spermatozoa and seminal plasma of proven fertile men and in testicular tissue of men with obstructive azoospermia. Abu-Halima, M.; Galata, V.; Backes, C.; Keller, A.; Hammadeh, M.; and Meese, E. Andrologia,e13503. 2019.
doi   link   bibtex   abstract  
DynaVenn: web-based computation of the most significant overlap between ordered sets. Amand, J.; Fehlmann, T.; Backes, C.; and Keller, A. BMC Bioinformatics, 20. 2019.
doi   link   bibtex  
  2018 (25)
miRCarta: a central repository for collecting miRNA candidates. Backes, C.; Fehlmann, T.; Kern, F.; Kehl, T.; Lenhof, H.; Meese, E.; and Keller, A. Nucleic acids research, 46: D160–D167. January 2018.
doi   link   bibtex   abstract  
IMOTA: an interactive multi-omics tissue atlas for the analysis of human miRNA-target interactions. Palmieri, V.; Backes, C.; Ludwig, N.; Fehlmann, T.; Kern, F.; Meese, E.; and Keller, A. Nucleic acids research, 46: D770–D775. January 2018.
doi   link   bibtex   abstract  
Characterization of micro-RNA Profile in the Blood of Patients with Marfan's Syndrome. Abu-Halima, M.; Ludwig, N.; Rädle-Hurst, T.; Keller, A.; Motsch, L.; Marsollek, I.; El Rahman, M. A.; Abdul-Khaliq, H.; and Meese, E. The Thoracic and cardiovascular surgeon, 66: 116–124. January 2018.
doi   link   bibtex   abstract  
Micro-RNA Regulated Pro-Angiogenic Signaling in Arteriovenous Loops in Patients with Combined Vascular and Soft Tissue Reconstructions - Reisiting the Nutrient Flap Concept. Henn, D.; Abu-Halima, M.; Falkner, F.; Wermke, D.; Meme, L. G; Kühner, C.; Keller, A.; Kneser, U.; Meese, E.; and Schmidt, V. J Plastic and reconstructive surgery. July 2018.
doi   link   bibtex   abstract  
Insights Into Male Androgenetic Alopecia: Differential Gene Expression Profiling of Plucked Hair Follicles and Integration with Genetic Data. Hochfeld, L. M; Keller, A.; Anhalt, T.; Fricker, N.; for Androgenetic Alopecia Novel determinants (MAAN) Consortium, M.; Nöthen, M. M; and Heilmann-Heimbach, S. The Journal of investigative dermatology. July 2018.
doi   link   bibtex  
Genome-wide MicroRNA Expression Profiles in COPD: Early Predictors for Cancer Development. Keller, A.; Fehlmann, T.; Ludwig, N.; Kahraman, M.; Laufer, T.; Backes, C.; Vogelmeier, C.; Diener, C.; Biertz, F.; Herr, C.; Jörres, R. A; Lenhof, H.; Meese, E.; Bals, R.; and Group, C. S. Genomics, proteomics & bioinformatics. July 2018.
doi   link   bibtex   abstract  
The Iceman's Last Meal Consisted of Fat, Wild Meat, and Cereals. Maixner, F.; Turaev, D.; Cazenave-Gassiot, A.; Janko, M.; Krause-Kyora, B.; Hoopmann, M. R; Kusebauch, U.; Sartain, M.; Guerriero, G.; O'Sullivan, N.; Teasdale, M.; Cipollini, G.; Paladin, A.; Mattiangeli, V.; Samadelli, M.; Tecchiati, U.; Putzer, A.; Palazoglu, M.; Meissen, J.; Lösch, S.; Rausch, P.; Baines, J. F; Kim, B. J.; An, H.; Gostner, P.; Egarter-Vigl, E.; Malfertheiner, P.; Keller, A.; Stark, R. W; Wenk, M.; Bishop, D.; Bradley, D. G; Fiehn, O.; Engstrand, L.; Moritz, R. L; Doble, P.; Franke, A.; Nebel, A.; Oeggl, K.; Rattei, T.; Grimm, R.; and Zink, A. Current biology : CB. June 2018.
doi   link   bibtex   abstract  
The deterministic role of 5-mers in microRNA-gene targeting. Hart, M.; Kern, F.; Backes, C.; Rheinheimer, S.; Fehlmann, T.; Keller, A.; and Meese, E. RNA biology,1–7. May 2018.
doi   link   bibtex   abstract  
REGGAE: a novel approach for the identification of key transcriptional regulators. Kehl, T.; Schneider, L.; Kattler, K.; Stöckel, D.; Wegert, J.; Gerstner, N.; Ludwig, N.; Distler, U.; Schick, M.; Keller, U.; Tenzer, S.; Gessler, M.; Walter, J.; Keller, A.; Graf, N.; Meese, E.; and Lenhof, H. Bioinformatics (Oxford, England). May 2018.
doi   link   bibtex   abstract  
Small ncRNA-Seq Results of Human Tissues: Variations Depending on Sample Integrity. Ludwig, N.; Fehlmann, T.; Galata, V.; Franke, A.; Backes, C.; Meese, E.; and Keller, A. Clinical chemistry, 64: 1074–1084. July 2018.
doi   link   bibtex   abstract  
Deregulated microRNA and mRNA expression profiles in the peripheral blood of patients with Marfan syndrome. Abu-Halima, M.; Kahraman, M.; Henn, D.; Rädle-Hurst, T.; Keller, A.; Abdul-Khaliq, H.; and Meese, E. Journal of translational medicine, 16: 60. March 2018.
doi   link   bibtex   abstract  
A high-resolution map of the human small non-coding transcriptome. Fehlmann, T.; Backes, C.; Alles, J.; Fischer, U.; Hart, M.; Kern, F.; Langseth, H.; Rounge, T.; Umu, S. U.; Kahraman, M.; Laufer, T.; Haas, J.; Staehler, C.; Ludwig, N.; Hübenthal, M.; Meder, B.; Franke, A.; Lenhof, H.; Meese, E.; and Keller, A. Bioinformatics (Oxford, England), 34: 1621–1628. May 2018.
doi   link   bibtex   abstract  
Genomic structural variations lead to dysregulation of important coding and non-coding RNA species in dilated cardiomyopathy. Haas, J.; Mester, S.; Lai, A.; Frese, K. S; Sedaghat-Hamedani, F.; Kayvanpour, E.; Rausch, T.; Nietsch, R.; Boeckel, J.; Carstensen, A.; Völkers, M.; Dietrich, C.; Pils, D.; Amr, A.; Holzer, D. B; Martins Bordalo, D.; Oehler, D.; Weis, T.; Mereles, D.; Buss, S.; Riechert, E.; Wirsz, E.; Wuerstle, M.; Korbel, J. O; Keller, A.; Katus, H. A; Posch, A. E; and Meder, B. EMBO molecular medicine, 10: 107–120. January 2018.
doi   link   bibtex   abstract  
Gene amplification in mesenchymal stem cells and during differentiation towards adipocytes or osteoblasts. Altmayer, N. C.; Galata, V.; Warschburger, N.; Keller, A.; Meese, E.; and Fischer, U. Oncotarget, 9: 1803–1812. January 2018.
doi   link   bibtex   abstract  
Comparing genome versus proteome-based identification of clinical bacterial isolates. Galata, V.; Backes, C.; Laczny, C. C.; Hemmrich-Stanisak, G.; Li, H.; Smoot, L.; Posch, A. E.; Schmolke, S.; Bischoff, M.; von Müller, L.; Plum, A.; Franke, A.; and Keller, A. Briefings in bioinformatics, 19: 495–505. May 2018.
doi   link   bibtex   abstract  
MicroRNA in diagnosis and therapy monitoring of early-stage triple-negative breast cancer. Kahraman, M.; Röske, A.; Laufer, T.; Fehlmann, T.; Backes, C.; Kern, F.; Kohlhaas, J.; Schrörs, H.; Saiz, A.; Zabler, C.; Ludwig, N.; Fasching, P. A; Strick, R.; Rübner, M.; Beckmann, M. W; Meese, E.; Keller, A.; and Schrauder, M. G Scientific reports, 8(1): 11584. August 2018.
doi   link   bibtex   abstract  
Next generation sequencing analysis of total small noncoding RNAs from low input RNA from dried blood sampling. Pirritano, M.; Fehlmann, T.; Laufer, T.; Ludwig, N.; Gasparoni, G.; Li, Y.; Meese, E.; Keller, A.; and Simon, M. Analytical chemistry, 90: 11791-11796. September 2018.
doi   link   bibtex   abstract  
The pulmonary microbiome in sarcoidosis is similar to other parenchymal lung diseases. Becker, A.; Vella, G.; Herr, C.; Keller, A.; Laczny, C.; Beisswenger, C.; and Bals, R. European Respiratory Journal, 52: 1399-3003. November 2018.
doi   link   bibtex   abstract  
Comparison of initial oral microbiomes of young adults with and without cavitated dentin caries lesions using an in situ biofilm model. Rupf, S.; Laczny, C. C; Galata, V.; Backes, C.; Keller, A.; Umanskaya, N.; Erol, A.; Tierling, S.; Porto, C. L.; Walter, J.; Kirsch, J.; Hannig, M.; and Hannig, C. Scientific reports, 8: 14010. September 2018.
doi   link   bibtex   abstract  
Modulation of intracellular calcium signaling by microRNA-34a-5p. Diener, C.; Hart, M.; Alansary, D.; Poth, V.; Walch-Rückheim, B.; Menegatti, J.; Grässer, F.; Fehlmann, T.; Rheinheimer, S.; Niemeyer, B. A; Lenhof, H.; Keller, A.; and Meese, E. Cell death & disease, 9: 1008. September 2018.
doi   link   bibtex   abstract  
Micro-RNA–Regulated Proangiogenic Signaling in Arteriovenous Loops in Patients with Combined Vascular and Soft-Tissue Reconstructions: Revisiting the Nutrient Flap Concept. Henn, D.; Abu-Halima, M.; Falkner, F.; Wermke, D.; Meme, L. G; Kühner, C.; Keller, A.; Kneser, U.; Meese, E.; and Schmidt, V. J Plastic and reconstructive surgery, 142: 489e-502e. October 2018.
doi   link   bibtex   abstract  
PLSDB: a resource of complete bacterial plasmids. Galata, V.; Fehlmann, T.; Backes, C.; and Keller, A. Nucleic acids research, 47: D195-D202. October 2018.
doi   link   bibtex   abstract  
Gene Set Enrichment Analysis Suggests That Increased Rituximab-Mediated NK Cell Cytotoxicity after Vitamin D Substitution Is Driven By Upregulation of Interferon Alpha (IFN-a) Isoforms. Konstantinos Christofyllakis, F. N.; Stephan Stilgenbauer, D. K.; Evi Regitz, M. B.; and Andreas Keller, J. T. B. blood, 132: 3696. November 2018.
doi   link   bibtex   abstract  
Deregulated microRNA and mRNA expression profiles in the peripheral blood of patients with Marfan syndrome. Abu-Halima, M.; Kahraman, M.; Henn, D.; Rädle-Hurst, T.; Keller, A.; Abdul-Khaliq, H.; and Meese, E. Journal of translational medicine, 16: 60. December 2018.
doi   link   bibtex   abstract  
Circulating small non-coding RNAs associated with age, sex, smoking, body mass and physical activity. Rounge, T. B; Umu, S. U; Keller, A.; Meese, E.; Ursin, G.; Tretli, S.; Lyle, R.; and Langseth, H. Scientific reports, 8: 17650. December 2018.
doi   link   bibtex   abstract  
  2017 (28)
Transcriptomic Analysis of Intestinal Tissues from Two 90-Day Feeding Studies in Rats Using Genetically Modified MON810 Maize Varieties. Sharbati, J.; Bohmer, M.; Bohmer, N.; Keller, A.; Backes, C.; Franke, A.; Steinberg, P.; Zeljenková, D.; and Einspanier, R. Frontiers in genetics, 8: 222. 2017.
doi   link   bibtex   abstract  
A comprehensive profile of circulating RNAs in human serum. Umu, S. U.; Langseth, H.; Bucher-Johannessen, C.; Fromm, B.; Keller, A.; Meese, E.; Lauritzen, M.; Leithaug, M.; Lyle, R.; and Rounge, T. B. RNA Biology, 15(2): 242–250. dec 2017.
doi   link   bibtex  
Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy. Sedaghat-Hamedani, F.; Haas, J.; Zhu, F.; Geier, C.; Kayvanpour, E.; Liss, M.; Lai, A.; Frese, K.; Pribe-Wolferts, R.; Amr, A.; Li, D. T.; Samani, O. S.; Carstensen, A.; Bordalo, D. M.; Müller, M.; Fischer, C.; Shao, J.; Wang, J.; Nie, M.; Yuan, L.; Haßfeld, S.; Schwartz, C.; Zhou, M.; Zhou, Z.; Shu, Y.; Wang, M.; Huang, K.; Zeng, Q.; Cheng, L.; Fehlmann, T.; Ehlermann, P.; Keller, A.; Dieterich, C.; Streckfuß-Bömeke, K.; Liao, Y.; Gotthardt, M.; Katus, H. A; and Meder, B. European Heart Journal, 38(46): 3449–3460. oct 2017.
doi   link   bibtex  
A comprehensive, cell specific microRNA catalogue of human peripheral blood. Juzenas, S.; Venkatesh, G.; Hübenthal, M.; Hoeppner, M. P.; Du, Z. G.; Paulsen, M.; Rosenstiel, P.; Senger, P.; Hofmann-Apitius, M.; Keller, A.; Kupcinskas, L.; Franke, A.; and Hemmrich-Stanisak, G. Nucleic Acids Research, 45(16): 9290–9301. aug 2017.
doi   link   bibtex  
miRNAs in Ancient Tissue Specimens of the Tyrolean Iceman. Keller, A.; Kreis, S.; Leidinger, P.; Maixner, F.; Ludwig, N.; Backes, C.; Galata, V.; Guerriero, G.; Fehlmann, T.; Franke, A.; Meder, B.; Zink, A.; and Meese, E. Molecular biology and evolution, 34: 793–801. April 2017.
doi   link   bibtex   abstract  
A review of databases predicting the effects of SNPs in miRNA genes or miRNA-binding sites. Fehlmann, T.; Sahay, S.; Keller, A.; and Backes, C. Briefings in bioinformatics. November 2017.
doi   link   bibtex   abstract  
About miRNAs, miRNA seeds, target genes and target pathways. Kehl, T.; Backes, C.; Kern, F.; Fehlmann, T.; Ludwig, N.; Meese, E.; Lenhof, H.; and Keller, A. Oncotarget, 8: 107167–107175. December 2017.
doi   link   bibtex   abstract  
Altered miRNA-profile dependent on ART outcome in early pregnancy targets Wnt-pathway. Freis, A.; Keller, A.; Ludwig, N.; Meese, E.; Jauckus, J.; Rehnitz, J.; Capp, E.; Strowitzki, T.; and Germeyer, A. Reproduction (Cambridge, England), 154: 799–805. December 2017.
doi   link   bibtex   abstract  
Analysis of circulating microRNAs in patients with repaired Tetralogy of Fallot with and without heart failure. Abu-Halima, M.; Meese, E.; Keller, A.; Abdul-Khaliq, H.; and Rädle-Hurst, T. Journal of translational medicine, 15: 156. July 2017.
doi   link   bibtex   abstract  
Assessing the heterogeneity of in silico plasmid predictions based on whole-genome-sequenced clinical isolates. Laczny, C. C; Galata, V.; Plum, A.; Posch, A. E; and Keller, A. Briefings in bioinformatics. December 2017.
doi   link   bibtex   abstract  
Micro-ribonucleic acids and extracellular vesicles repertoire in the spent culture media is altered in women undergoing In Vitro Fertilization. Abu-Halima, M.; Häusler, S.; Backes, C.; Fehlmann, T.; Staib, C.; Nestel, S.; Nazarenko, I.; Meese, E.; and Keller, A. Scientific reports, 7: 13525. October 2017.
doi   link   bibtex   abstract  
Differential expression of microRNAs following cardiopulmonary bypass in children with congenital heart diseases. Abu-Halima, M.; Poryo, M.; Ludwig, N.; Mark, J.; Marsollek, I.; Giebels, C.; Petersen, J.; Schäfers, H.; Grundmann, U.; Pickardt, T.; Keller, A.; Meese, E.; and Abdul-Khaliq, H. Journal of translational medicine, 15: 117. May 2017.
doi   link   bibtex   abstract  
Web-based NGS data analysis using miRMaster: a large-scale meta-analysis of human miRNAs. Fehlmann, T.; Backes, C.; Kahraman, M.; Haas, J.; Ludwig, N.; Posch, A. E; Würstle, M. L; Hübenthal, M.; Franke, A.; Meder, B.; Meese, E.; and Keller, A. Nucleic acids research, 45: 8731–8744. September 2017.
doi   link   bibtex   abstract  
Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and a Novel Class of Biomarkers for Heart Failure. Meder, B.; Haas, J.; Sedaghat-Hamedani, F.; Kayvanpour, E.; Frese, K.; Lai, A.; Nietsch, R.; Scheiner, C.; Mester, S.; Bordalo, D. M.; Amr, A.; Dietrich, C.; Pils, D.; Siede, D.; Hund, H.; Bauer, A.; Holzer, D. B.; Ruhparwar, A.; Mueller-Hennessen, M.; Weichenhan, D.; Plass, C.; Weis, T.; Backs, J.; Wuerstle, M.; Keller, A.; Katus, H. A; and Posch, A. E Circulation, 136: 1528–1544. October 2017.
doi   link   bibtex   abstract  
Technical Stability and Biological Variability in MicroRNAs from Dried Blood Spots: A Lung Cancer Therapy-Monitoring Showcase. Kahraman, M.; Laufer, T.; Backes, C.; Schrörs, H.; Fehlmann, T.; Ludwig, N.; Kohlhaas, J.; Meese, E.; Wehler, T.; Bals, R.; and Keller, A. Clinical chemistry, 63: 1476–1488. September 2017.
doi   link   bibtex   abstract  
Genotype-phenotype associations in dilated cardiomyopathy: meta-analysis on more than 8000 individuals. Kayvanpour, E.; Sedaghat-Hamedani, F.; Amr, A.; Lai, A.; Haas, J.; Holzer, D. B; Frese, K. S; Keller, A.; Jensen, K.; Katus, H. A; and Meder, B. Clinical research in cardiology : official journal of the German Cardiac Society, 106: 127–139. February 2017.
doi   link   bibtex   abstract  
MiR-148a impairs Ras/ERK signaling in B lymphocytes by targeting SOS proteins. Alles, J.; Ludwig, N.; Rheinheimer, S.; Leidinger, P.; Grässer, F. A; Keller, A.; and Meese, E. Oncotarget, 8: 56417–56427. August 2017.
doi   link   bibtex   abstract  
Sources to variability in circulating human miRNA signatures. Keller, A.; Rounge, T.; Backes, C.; Ludwig, N.; Gislefoss, R.; Leidinger, P.; Langseth, H.; and Meese, E. RNA biology, 14: 1791–1798. December 2017.
doi   link   bibtex   abstract  
TRPC1- and TRPC3-dependent Ca, javax.xml.bind.JAXBElement@c75b5d8, signaling in mouse cortical astrocytes affects injury-evoked astrogliosis in vivo. Belkacemi, T.; Niermann, A.; Hofmann, L.; Wissenbach, U.; Birnbaumer, L.; Leidinger, P.; Backes, C.; Meese, E.; Keller, A.; Bai, X.; Scheller, A.; Kirchhoff, F.; Philipp, S. E; Weissgerber, P.; Flockerzi, V.; and Beck, A. Glia, 65: 1535–1549. September 2017.
doi   link   bibtex   abstract  
Bias in recent miRBase annotations potentially associated with RNA quality issues. Ludwig, N.; Becker, M.; Schumann, T.; Speer, T.; Fehlmann, T.; Keller, A.; and Meese, E. Scientific reports, 7: 5162. July 2017.
doi   link   bibtex   abstract  
BusyBee Web: metagenomic data analysis by bootstrapped supervised binning and annotation. Laczny, C. C; Kiefer, C.; Galata, V.; Fehlmann, T.; Backes, C.; and Keller, A. Nucleic acids research, 45: W171–W179. July 2017.
doi   link   bibtex   abstract  
RegulatorTrail: a web service for the identification of key transcriptional regulators. Kehl, T.; Schneider, L.; Schmidt, F.; Stöckel, D.; Gerstner, N.; Backes, C.; Meese, E.; Keller, A.; Schulz, M. H; and Lenhof, H. Nucleic acids research, 45: W146–W153. July 2017.
doi   link   bibtex   abstract  
LitDB - Keeping Track of Research Papers From Your Institute Made Simple. Bethune, J.; Kraemer, L.; Thomsen, I.; Keller, A.; Ellinghaus, D.; and Franke, A. Source code for biology and medicine, 12: 5. 2017.
doi   link   bibtex   abstract  
MiR-34a-3p alters proliferation and apoptosis of meningioma cells , javax.xml.bind.JAXBElement@3565bad6, and is directly targeting SMAD4, FRAT1 and BCL2. Werner, T. V; Hart, M.; Nickels, R.; Kim, Y.; Menger, M. D; Bohle, R. M; Keller, A.; Ludwig, N.; and Meese, E. Aging, 9: 932–954. March 2017.
doi   link   bibtex   abstract  
Specific amplifications and copy number decreases during human neural stem cells differentiation towards astrocytes, neurons and oligodendrocytes. Fischer, U.; Kim, E.; Keller, A.; and Meese, E. Oncotarget, 8: 25872–25884. April 2017.
doi   link   bibtex   abstract  
Exploring ncRNAs in Alzheimer's disease by miRMaster. Fehlmann, T.; Meese, E.; and Keller, A. Oncotarget, 8: 3771–3772. January 2017.
doi   link   bibtex  
miRPathDB: a new dictionary on microRNAs and target pathways. Backes, C.; Kehl, T.; Stöckel, D.; Fehlmann, T.; Schneider, L.; Meese, E.; Lenhof, H.; and Keller, A. Nucleic acids research, 45: D90–D96. January 2017.
doi   link   bibtex   abstract  
The miRNome of Alzheimer's disease: consistent downregulation of the miR-132/212 cluster. Pichler, S.; Gu, W.; Hartl, D.; Gasparoni, G.; Leidinger, P.; Keller, A.; Meese, E.; Mayhaus, M.; Hampel, H.; and Riemenschneider, M. Neurobiology of aging, 50: 167.e1–167.e10. February 2017.
doi   link   bibtex   abstract  
  2016 (28)
cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAs. Fehlmann, T.; Reinheimer, S.; Geng, C.; Su, X.; Drmanac, S.; Alexeev, A.; Zhang, C.; Backes, C.; Ludwig, N.; Hart, M.; An, D.; Zhu, Z.; Xu, C.; Chen, A.; Ni, M.; Liu, J.; Li, Y.; Poulter, M.; Li, Y.; Stahler, C.; Drmanac, R.; Xu, X.; Meese, E.; and Keller, A. Clin Epigenetics, 8: 123. 2016.
link   bibtex  
miRNA assays in the clinical laboratory: Workflow, detection technologies and automation aspects. Kappel, A.; and Keller, A. Clin. Chem. Lab. Med.. Dec 2016.
link   bibtex  
Computational Cardiology - A New Discipline of Translational Research. Meder, B.; Katus, H. A.; and Keller, A. Genomics Proteomics Bioinformatics, 14(4): 177–178. Aug 2016.
link   bibtex  
Distribution of microRNA biomarker candidates in solid tissues and body fluids. Fehlmann, T.; Ludwig, N.; Backes, C.; Meese, E.; and Keller, A. RNA Biol, 13(11): 1084–1088. Nov 2016.
link   bibtex  
Paired proteomics, transcriptomics and miRNomics in non-small cell lung cancers: known and novel signaling cascades. Backes, C.; Ludwig, N.; Leidinger, P.; Huwer, H.; Tenzer, S.; Fehlmann, T.; Franke, A.; Meese, E.; Lenhof, H. P.; and Keller, A. Oncotarget. Aug 2016.
link   bibtex  
miRNAs and sports: tracking training status and potentially confounding diagnoses. Hecksteden, A.; Leidinger, P.; Backes, C.; Rheinheimer, S.; Pfeiffer, M.; Ferrauti, A.; Kellmann, M.; Sedaghat, F.; Meder, B.; Meese, E.; Meyer, T.; and Keller, A. J Transl Med, 14(1): 219. 2016.
link   bibtex  
MicroRNA Response of Primary Human Macrophages to Arcobacter Butzleri Infection. Zur Bruegge, J.; Backes, C.; Golz, G.; Hemmrich-Stanisak, G.; Scharek-Tedin, L.; Franke, A.; Alter, T.; Einspanier, R.; Keller, A.; and Sharbati, S. Eur. J. Microbiol. Immunol., 6(2): 99–108. Jun 2016.
link   bibtex  
Identification of miR-34a-target interactions by a combined network based and experimental approach. Hart, M.; Rheinheimer, S.; Leidinger, P.; Backes, C.; Menegatti, J.; Fehlmann, T.; Grasser, F.; Keller, A.; and Meese, E. Oncotarget. Apr 2016.
link   bibtex  
Syntaxin 8 is required for efficient lytic granule trafficking in cytotoxic T lymphocytes. Bhat, S. S.; Friedmann, K. S.; Knorck, A.; Hoxha, C.; Leidinger, P.; Backes, C.; Meese, E.; Keller, A.; Rettig, J.; Hoth, M.; Qu, B.; and Schwarz, E. C. Biochim. Biophys. Acta, 1863(7 Pt A): 1653–1664. Apr 2016.
link   bibtex  
miEAA: microRNA enrichment analysis and annotation. Backes, C.; Khaleeq, Q. T.; Meese, E.; and Keller, A. Nucleic Acids Res.. Apr 2016.
link   bibtex  
miRTargetLink-miRNAs, Genes and Interaction Networks. Hamberg, M.; Backes, C.; Fehlmann, T.; Hart, M.; Meder, B.; Meese, E.; and Keller, A. Int J Mol Sci, 17(4). 2016.
link   bibtex  
Combining miRNA and mRNA Expression Profiles in Wilms Tumor Subtypes. Ludwig, N.; Werner, T. V.; Backes, C.; Trampert, P.; Gessler, M.; Keller, A.; Lenhof, H. P.; Graf, N.; and Meese, E. Int J Mol Sci, 17(4). 2016.
link   bibtex  
BALL-SNPgp-from genetic variants toward computational diagnostics. Mueller, S. C.; Backes, C.; Gress, A.; Baumgarten, N.; Kalinina, O. V.; Moll, A.; Kohlbacher, O.; Meese, E.; and Keller, A. Bioinformatics. Feb 2016.
link   bibtex  
StructMAn: annotation of single-nucleotide polymorphisms in the structural context. Gress, A.; Ramensky, V.; Buch, J.; Keller, A.; and Kalinina, O. V. Nucleic Acids Res.. May 2016.
link   bibtex  
Integrated quantitative proteomic and transcriptomic analysis of lung tumor and control tissue: a lung cancer showcase. Tenzer, S.; Leidinger, P.; Backes, C.; Huwer, H.; Hildebrandt, A.; Lenhof, H. P.; Wesse, T.; Franke, A.; Meese, E.; and Keller, A. Oncotarget. Feb 2016.
link   bibtex  
Differential blood-based diagnosis between benign prostatic hyperplasia and prostate cancer: miRNA as source for biomarkers independent of PSA level, Gleason score, or TNM status. Leidinger, P.; Hart, M.; Backes, C.; Rheinheimer, S.; Keck, B.; Wullich, B.; Keller, A.; and Meese, E. Tumour Biol.. Jan 2016.
link   bibtex  
Bias in High-Throughput Analysis of miRNAs and Implications for Biomarker Studies. Backes, C.; Sedaghat-Hamedani, F.; Frese, K.; Hart, M.; Ludwig, N.; Meder, B.; Meese, E.; and Keller, A. Anal. Chem.. Jan 2016.
link   bibtex  
Multi-omics Enrichment Analysis using the GeneTrail2 Web Service. Stoeckel, D.; Kehl, T.; Trampert, P.; Schneider, L.; Backes, C.; Ludwig, N.; Gerasch, A.; Kaufmann, M.; Gessler, M.; Graf, N.; Meese, E.; Keller, A.; and Lenhof, H. P. Bioinformatics. Jan 2016.
link   bibtex  
EDISON-WMW: Exact Dynamic Programing Solution of the Wilcoxon-Mann-Whitney Test. Marx, A.; Backes, C.; Meese, E.; Lenhof, H.; and Keller, A. Genomics Proteomics Bioinformatics, 14(1): 55–61. Feb 2016.
link   bibtex  
Altered micro-ribonucleic acid expression profiles of extracellular microvesicles in the seminal plasma of patients with oligoasthenozoospermia. Abu-Halima, M.; Ludwig, N.; Hart, M.; Leidinger, P.; Backes, C.; Keller, A.; Hammadeh, M.; and Meese, E. Fertility and sterility, 106: 1061–1069.e3. October 2016.
doi   link   bibtex   abstract  
The Role of Quality Control in Targeted Next-generation Sequencing Library Preparation. Nietsch, R.; Haas, J.; Lai, A.; Oehler, D.; Mester, S.; Frese, K. S; Sedaghat-Hamedani, F.; Kayvanpour, E.; Keller, A.; and Meder, B. Genomics, proteomics & bioinformatics, 14: 200–206. August 2016.
doi   link   bibtex   abstract  
Deep characterization of blood cell miRNomes by NGS. Schwarz, E. C; Backes, C.; Knörck, A.; Ludwig, N.; Leidinger, P.; Hoxha, C.; Schwär, G.; Grossmann, T.; Müller, S. C; Hart, M.; Haas, J.; Galata, V.; Müller, I.; Fehlmann, T.; Eichler, H.; Franke, A.; Meder, B.; Meese, E.; Hoth, M.; and Keller, A. Cellular and molecular life sciences : CMLS, 73: 3169–3181. August 2016.
doi   link   bibtex   abstract   1 download  
Validating Alzheimer's disease micro RNAs using next-generation sequencing. Keller, A.; Backes, C.; Haas, J.; Leidinger, P.; Maetzler, W.; Deuschle, C.; Berg, D.; Ruschil, C.; Galata, V.; Ruprecht, K.; Stähler, C.; Würstle, M.; Sickert, D.; Gogol, M.; Meder, B.; and Meese, E. Alzheimer's & dementia : the journal of the Alzheimer's Association, 12: 565–576. May 2016.
doi   link   bibtex   abstract  
From Single Variants to Protein Cascades: MULTISCALE MODELING OF SINGLE NUCLEOTIDE VARIANT SETS IN GENETIC DISORDERS. Mueller, S. C; Sommer, B.; Backes, C.; Haas, J.; Meder, B.; Meese, E.; and Keller, A. The Journal of biological chemistry, 291: 1582–1590. January 2016.
doi   link   bibtex   abstract  
High-throughput qRT-PCR validation of blood microRNAs in non-small cell lung cancer. Leidinger, P.; Brefort, T.; Backes, C.; Krapp, M.; Galata, V.; Beier, M.; Kohlhaas, J.; Huwer, H.; Meese, E.; and Keller, A. Oncotarget, 7: 4611–4623. January 2016.
doi   link   bibtex   abstract  
Prioritizing and selecting likely novel miRNAs from NGS data. Backes, C.; Meder, B.; Hart, M.; Ludwig, N.; Leidinger, P.; Vogel, B.; Galata, V.; Roth, P.; Menegatti, J.; Grässer, F.; Ruprecht, K.; Kahraman, M.; Grossmann, T.; Haas, J.; Meese, E.; and Keller, A. Nucleic acids research, 44: e53. April 2016.
doi   link   bibtex   abstract  
Distribution of miRNA expression across human tissues. Ludwig, N.; Leidinger, P.; Becker, K.; Backes, C.; Fehlmann, T.; Pallasch, C.; Rheinheimer, S.; Meder, B.; Stähler, C.; Meese, E.; and Keller, A. Nucleic acids research, 44(8): 3865–3877. May 2016.
doi   link   bibtex   abstract  
Specific miRNA Disease Biomarkers in Blood, Serum and Plasma: Challenges and Prospects. Backes, C.; Meese, E.; and Keller, A. Molecular diagnosis & therapy, 20(6): 509–518. December 2016.
doi   link   bibtex   abstract  
  2015 (32)
Can circulating miRNAs live up to the promise of being minimal invasive biomarkers in clinical settings?. Keller, A.; and Meese, E. Wiley Interdiscip Rev RNA. Dec 2015.
link   bibtex  
Biomarker changes after strenuous exercise can mimic pulmonary embolism and cardiac injury–a metaanalysis of 45 studies. Sedaghat-Hamedani, F.; Kayvanpour, E.; Frankenstein, L.; Mereles, D.; Amr, A.; Buss, S.; Keller, A.; Giannitsis, E.; Jensen, K.; Katus, H. A.; and Meder, B. Clin. Chem., 61(10): 1246–1255. Oct 2015.
link   bibtex  
Towards Clinical Applications of Blood-Borne miRNA Signatures: The Influence of the Anticoagulant EDTA on miRNA Abundance. Leidinger, P.; Backes, C.; Rheinheimer, S.; Keller, A.; and Meese, E. PLoS ONE, 10(11): e0143321. 2015.
link   bibtex  
Pathway-based variant enrichment analysis on the example of dilated cardiomyopathy. Backes, C.; Meder, B.; Lai, A.; Stoll, M.; Ruhle, F.; Katus, H. A.; and Keller, A. Hum. Genet.. Nov 2015.
link   bibtex  
DrugTargetInspector: An assistance tool for patient treatment stratification. Schneider, L.; Stoeckel, D.; Kehl, T.; Gerasch, A.; Ludwig, N.; Leidinger, P.; Huwer, H.; Tenzer, S.; Kohlbacher, O.; Hildebrandt, A.; Kaufmann, M.; Gessler, M.; Keller, A.; Meese, E.; Graf, N.; and Lenhof, H. P. Int. J. Cancer. Oct 2015.
link   bibtex  
Genome-wide copy number profiling of mouse neural stem cells during differentiation. Fischer, U.; Ludwig, N.; Keller, A.; Backes, C.; and Meese, E. Genom. Data, 5: 3–6. Sep 2015.
link   bibtex  
Sparse Modeling Reveals miRNA Signatures for Diagnostics of Inflammatory Bowel Disease. Hubenthal, M.; Hemmrich-Stanisak, G.; Degenhardt, F.; Szymczak, S.; Du, Z.; Elsharawy, A.; Keller, A.; Schreiber, S.; and Franke, A. PLoS ONE, 10(10): e0140155. 2015.
link   bibtex  
Influence of next-generation sequencing and storage conditions on miRNA patterns generated from PAXgene blood. Backes, C.; Leidinger, P.; Altmann, G.; Wuerstle, M.; Meder, B.; Galata, V.; Mueller, S. C.; Sickert, D.; Stahler, C.; Meese, E.; and Keller, A. Anal. Chem., 87(17): 8910–8916. Sep 2015.
link   bibtex  
Exome Sequencing Analysis Reveals Variants in Primary Immunodeficiency Genes in Patients With Very Early Onset Inflammatory Bowel Disease. Kelsen, J. R.; Dawany, N.; Moran, C. J.; Petersen, B. S.; Sarmady, M.; Sasson, A.; Pauly-Hubbard, H.; Martinez, A.; Maurer, K.; Soong, J.; Rappaport, E.; Franke, A.; Keller, A.; Winter, H. S.; Mamula, P.; Piccoli, D.; Artis, D.; Sonnenberg, G. F.; Daly, M.; Sullivan, K. E.; Baldassano, R. N.; and Devoto, M. Gastroenterology, 149(6): 1415–1424. Nov 2015.
link   bibtex  
BALL-SNP: combining genetic and structural information to identify candidate non-synonymous single nucleotide polymorphisms. Mueller, S. C.; Backes, C.; Kalinina, O. V.; Meder, B.; Stoeckel, D.; Lenhof, H. P.; Meese, E.; and Keller, A. Genome Med., 7(1): 65. 2015.
link   bibtex  
Regulatory microRNA networks: complex patterns of target pathways for disease-related and housekeeping microRNAs. Zafari, S.; Backes, C.; Leidinger, P.; Meese, E.; and Keller, A. Genomics Proteomics Bioinformatics, 13(3): 159–168. Jun 2015.
link   bibtex  
Longitudinal study on circulating miRNAs in patients after lung cancer resection. Leidinger, P.; Galata, V.; Backes, C.; Stahler, C.; Rheinheimer, S.; Huwer, H.; Meese, E.; and Keller, A. Oncotarget, 6(18): 16674–16685. Jun 2015.
link   bibtex  
Combination of Autoantibody Signature with PSA Level Enables a Highly Accurate Blood-Based Differentiation of Prostate Cancer Patients from Patients with Benign Prostatic Hyperplasia. Leidinger, P.; Keller, A.; Milchram, L.; Harz, C.; Hart, M.; Werth, A.; Lenhof, H. P.; Weinhausel, A.; Keck, B.; Wullich, B.; Ludwig, N.; and Meese, E. PLoS ONE, 10(6): e0128235. 2015.
link   bibtex  
Reanalysis of 3,707 novel human microRNA candidates. Backes, C.; and Keller, A. Proc. Natl. Acad. Sci. U.S.A., 112(22): E2849–2850. Jun 2015.
link   bibtex  
Circulating serum miRNAs as potential biomarkers for nephroblastoma. Ludwig, N.; Nourkami-Tutdibi, N.; Backes, C.; Lenhof, H. P.; Graf, N.; Keller, A.; and Meese, E. Pediatr. Blood Cancer, 62(8): 1360–1367. Aug 2015.
link   bibtex  
Gene amplification during differentiation of mammalian neural stem cells in vitro and in vivo. Fischer, U.; Backes, C.; Raslan, A.; Keller, A.; Meier, C.; and Meese, E. Oncotarget, 6(9): 7023–7039. Mar 2015.
link   bibtex  
Circulating Biomarker Panels in Alzheimer's Disease. Zafari, S.; Backes, C.; Meese, E.; and Keller, A. Gerontology, 61(6): 497–503. 2015.
link   bibtex  
Posttranscriptional deregulation of signaling pathways in meningioma subtypes by differential expression of miRNAs. Ludwig, N.; Kim, Y. J.; Mueller, S. C.; Backes, C.; Werner, T. V.; Galata, V.; Sartorius, E.; Bohle, R. M.; Keller, A.; and Meese, E. Neuro Oncol., 17(9): 1250–1260. Sep 2015.
link   bibtex  
Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors. Wegert, J.; Ishaque, N.; Vardapour, R.; Georg, C.; Gu, Z.; Bieg, M.; Ziegler, B.; Bausenwein, S.; Nourkami, N.; Ludwig, N.; Keller, A.; Grimm, C.; Kneitz, S.; Williams, R. D.; Chagtai, T.; Pritchard-Jones, K.; van Sluis, P.; Volckmann, R.; Koster, J.; Versteeg, R.; Acha, T.; O'Sullivan, M. J.; Bode, P. K.; Niggli, F.; Tytgat, G. A.; van Tinteren, H.; van den Heuvel-Eibrink, M. M.; Meese, E.; Vokuhl, C.; Leuschner, I.; Graf, N.; Eils, R.; Pfister, S. M.; Kool, M.; and Gessler, M. Cancer Cell, 27(2): 298–311. Feb 2015.
link   bibtex  
Natalizumab restores aberrant miRNA expression profile in multiple sclerosis and reveals a critical role for miR-20b. Ingwersen, J.; Menge, T.; Wingerath, B.; Kaya, D.; Graf, J.; Prozorovski, T.; Keller, A.; Backes, C.; Beier, M.; Scheffler, M.; Dehmel, T.; Kieseier, B. C.; Hartung, H. P.; Kury, P.; and Aktas, O. Ann. Clin. Transl. Neurol., 2(1): 43–55. Jan 2015.
link   bibtex  
MicroRNA in vitro diagnostics using immunoassay analyzers. Kappel, A.; Backes, C.; Huang, Y.; Zafari, S.; Leidinger, P.; Meder, B.; Schwarz, H.; Gumbrecht, W.; Meese, E.; Staehler, C. F.; and Keller, A. Clin. Chem., 61(4): 600–607. Apr 2015.
link   bibtex  
New insights into the genetics of glioblastoma multiforme by familial exome sequencing. Backes, C.; Harz, C.; Fischer, U.; Schmitt, J.; Ludwig, N.; Petersen, B. S.; Mueller, S. C.; Kim, Y. J.; Wolf, N. M.; Katus, H. A.; Meder, B.; Furtwangler, R.; Franke, A.; Bohle, R.; Henn, W.; Graf, N.; Keller, A.; and Meese, E. Oncotarget, 6(8): 5918–5931. Mar 2015.
link   bibtex  
Differentially regulated miRNAs as prognostic biomarkers in the blood of primary CNS lymphoma patients. Roth, P.; Keller, A.; Hoheisel, J. D.; Codo, P.; Bauer, A. S.; Backes, C.; Leidinger, P.; Meese, E.; Thiel, E.; Korfel, A.; and Weller, M. Eur. J. Cancer, 51(3): 382–390. Feb 2015.
link   bibtex  
XIAP variants in male Crohn's disease. Zeissig, Y.; Petersen, B. S.; Milutinovic, S.; Bosse, E.; Mayr, G.; Peuker, K.; Hartwig, J.; Keller, A.; Kohl, M.; Laass, M. W.; Billmann-Born, S.; Brandau, H.; Feller, A. C.; Rocken, C.; Schrappe, M.; Rosenstiel, P.; Reed, J. C.; Schreiber, S.; Franke, A.; and Zeissig, S. Gut, 64(1): 66–76. Jan 2015.
link   bibtex  
Double-Stranded Ligation Assay for the Rapid Multiplex Quantification of MicroRNAs. Hofmann, S.; Huang, Y.; Paulicka, P.; Kappel, A.; Katus, H. A; Keller, A.; Meder, B.; Stähler, C. F.; and Gumbrecht, W. Analytical chemistry, 87: 12104–12111. December 2015.
doi   link   bibtex   abstract  
A novel whole-blood miRNA signature for a rapid diagnosis of pulmonary tuberculosis. Latorre, I.; Leidinger, P.; Backes, C.; Domínguez, J.; de Souza-Galvão, M. L.; Maldonado, J.; Prat, C.; Ruiz-Manzano, J.; Sánchez, F.; Casas, I.; Keller, A.; von Briesen, H.; Knobel, H.; Meese, E.; and Meyerhans, A. The European respiratory journal, 45: 1173–1176. April 2015.
doi   link   bibtex  
Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis. Keller, A.; Leidinger, P.; Meese, E.; Haas, J.; Backes, C.; Rasche, L.; Behrens, J. R; Pfuhl, C.; Wakonig, K.; Gieß, R. M; Jarius, S.; Meder, B.; Bellmann-Strobl, J.; Paul, F.; Pache, F. C; and Ruprecht, K. Journal of neuroinflammation, 12: 196. October 2015.
doi   link   bibtex   abstract  
Towards Personalized Cardiology: Multi-Scale Modeling of the Failing Heart. Kayvanpour, E.; Mansi, T.; Sedaghat-Hamedani, F.; Amr, A.; Neumann, D.; Georgescu, B.; Seegerer, P.; Kamen, A.; Haas, J.; Frese, K. S; Irawati, M.; Wirsz, E.; King, V.; Buss, S.; Mereles, D.; Zitron, E.; Keller, A.; Katus, H. A; Comaniciu, D.; and Meder, B. PloS one, 10: e0134869. 2015.
doi   link   bibtex   abstract  
miFRame: analysis and visualization of miRNA sequencing data in neurological disorders. Backes, C.; Haas, J.; Leidinger, P.; Frese, K.; Großmann, T.; Ruprecht, K.; Meder, B.; Meese, E.; and Keller, A. Journal of translational medicine, 13: 224. July 2015.
doi   link   bibtex   abstract  
RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish. Frese, K. S; Meder, B.; Keller, A.; Just, S.; Haas, J.; Vogel, B.; Fischer, S.; Backes, C.; Matzas, M.; Köhler, D.; Benes, V.; Katus, H. A; and Rottbauer, W. Journal of cell science, 128: 3030–3040. August 2015.
doi   link   bibtex   abstract  
Pathogenicity prediction of non-synonymous single nucleotide variants in dilated cardiomyopathy. Mueller, S. C; Backes, C.; Haas, J.; Group, I. S.; Katus, H. A; Meder, B.; Meese, E.; and Keller, A. Briefings in bioinformatics, 16: 769–779. September 2015.
doi   link   bibtex   abstract  
Atlas of the clinical genetics of human dilated cardiomyopathy. Haas, J.; Frese, K. S; Peil, B.; Kloos, W.; Keller, A.; Nietsch, R.; Feng, Z.; Müller, S.; Kayvanpour, E.; Vogel, B.; Sedaghat-Hamedani, F.; Lim, W.; Zhao, X.; Fradkin, D.; Köhler, D.; Fischer, S.; Franke, J.; Marquart, S.; Barb, I.; Li, D. T.; Amr, A.; Ehlermann, P.; Mereles, D.; Weis, T.; Hassel, S.; Kremer, A.; King, V.; Wirsz, E.; Isnard, R.; Komajda, M.; Serio, A.; Grasso, M.; Syrris, P.; Wicks, E.; Plagnol, V.; Lopes, L.; Gadgaard, T.; Eiskjær, H.; Jørgensen, M.; Garcia-Giustiniani, D.; Ortiz-Genga, M.; Crespo-Leiro, M. G; Deprez, R. H L. D.; Christiaans, I.; van Rijsingen, I. A; Wilde, A. A; Waldenstrom, A.; Bolognesi, M.; Bellazzi, R.; Mörner, S.; Bermejo, J. L.; Monserrat, L.; Villard, E.; Mogensen, J.; Pinto, Y. M; Charron, P.; Elliott, P.; Arbustini, E.; Katus, H. A; and Meder, B. European heart journal, 36: 1123–135a. May 2015.
doi   link   bibtex   abstract  
  2014 (18)
Genome-wide copy number profiling to detect gene amplifications in neural progenitor cells. Fischer, U.; Keller, A.; Backes, C.; and Meese, E. Genom. Data, 2: 162–165. Dec 2014.
link   bibtex  
What makes a blood cell based miRNA expression pattern disease specific? – a miRNome analysis of blood cell subsets in lung cancer patients and healthy controls. Leidinger, P.; Backes, C.; Dahmke, I. N.; Galata, V.; Huwer, H.; Stehle, I.; Bals, R.; Keller, A.; and Meese, E. Oncotarget, 5(19): 9484–9497. Oct 2014.
link   bibtex  
The blood-borne miRNA signature of lung cancer patients is independent of histology but influenced by metastases. Leidinger, P.; Backes, C.; Blatt, M.; Keller, A.; Huwer, H.; Lepper, P.; Bals, R.; and Meese, E. Mol. Cancer, 13: 202. 2014.
link   bibtex  
Secretion and immunogenicity of the meningioma-associated antigen TXNDC16. Harz, C.; Ludwig, N.; Lang, S.; Werner, T. V.; Galata, V.; Backes, C.; Schmitt, K.; Nickels, R.; Krause, E.; Jung, M.; Rettig, J.; Keller, A.; Menger, M.; Zimmermann, R.; and Meese, E. J. Immunol., 193(6): 3146–3154. Sep 2014.
link   bibtex  
The TGF-$β$-inducible miR-23a cluster attenuates IFN-$γ$ levels and antigen-specific cytotoxicity in human CD8\textsuperscript+ T cells. Chandran, P. A.; Keller, A.; Weinmann, L.; Seida, A. A.; Braun, M.; Andreev, K.; Fischer, B.; Horn, E.; Schwinn, S.; Junker, M.; Houben, R.; Dombrowski, Y.; Dietl, J.; Finotto, S.; Wolfl, M.; Meister, G.; and Wischhusen, J. J. Leukoc. Biol., 96(4): 633–645. Oct 2014.
link   bibtex  
Blood born miRNAs signatures that can serve as disease specific biomarkers are not significantly affected by overall fitness and exercise. Backes, C.; Leidinger, P.; Keller, A.; Hart, M.; Meyer, T.; Meese, E.; and Hecksteden, A. PLoS ONE, 9(7): e102183. 2014.
link   bibtex  
The human miRNA repertoire of different blood compounds. Leidinger, P.; Backes, C.; Meder, B.; Meese, E.; and Keller, A. BMC Genomics, 15: 474. 2014.
link   bibtex  
Comprehensive analysis of microRNA profiles in multiple sclerosis including next-generation sequencing. Keller, A.; Leidinger, P.; Steinmeyer, F.; Stahler, C.; Franke, A.; Hemmrich-Stanisak, G.; Kappel, A.; Wright, I.; Dorr, J.; Paul, F.; Diem, R.; Tocariu-Krick, B.; Meder, B.; Backes, C.; Meese, E.; and Ruprecht, K. Mult. Scler., 20(3): 295–303. Mar 2014.
link   bibtex  
Evaluation of microRNAs by molecular imaging for novel diagnostics and therapeutics. Kloos, W.; Keller, A.; Katus, H. A.; and Meder, B Heart Metab., 65: 15-20. 2014.
link   bibtex  
Population genomic analysis of ancient and modern genomes yields new insights into the genetic ancestry of the Tyrolean Iceman and the genetic structure of Europe. Sikora, M.; Carpenter, M. L; Moreno-Estrada, A.; Henn, B. M; Underhill, P. A; Sánchez-Quinto, F.; Zara, I.; Pitzalis, M.; Sidore, C.; Busonero, F.; Maschio, A.; Angius, A.; Jones, C.; Mendoza-Revilla, J.; Nekhrizov, G.; Dimitrova, D.; Theodossiev, N.; Harkins, T. T; Keller, A.; Maixner, F.; Zink, A.; Abecasis, G.; Sanna, S.; Cucca, F.; and Bustamante, C. D PLoS genetics, 10: e1004353. May 2014.
doi   link   bibtex   abstract  
Genomic correlates of atherosclerosis in ancient humans. Zink, A.; Wann, L S.; Thompson, R. C; Keller, A.; Maixner, F.; Allam, A. H; Finch, C. E; Frohlich, B.; Kaplan, H.; Lombardi, G. P; Sutherland, M L.; Sutherland, J. D; Watson, L.; Cox, S. L; Miyamoto, M. I; Narula, J.; Stewart, A. F R; Thomas, G. S; and Krause, J. Global heart, 9: 203–209. June 2014.
doi   link   bibtex   abstract  
A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy. Meder, B.; Rühle, F.; Weis, T.; Homuth, G.; Keller, A.; Franke, J.; Peil, B.; Lorenzo Bermejo, J.; Frese, K.; Huge, A.; Witten, A.; Vogel, B.; Haas, J.; Völker, U.; Ernst, F.; Teumer, A.; Ehlermann, P.; Zugck, C.; Friedrichs, F.; Kroemer, H.; Dörr, M.; Hoffmann, W.; Maisch, B.; Pankuweit, S.; Ruppert, V.; Scheffold, T.; Kühl, U.; Schultheiss, H.; Kreutz, R.; Ertl, G.; Angermann, C.; Charron, P.; Villard, E.; Gary, F.; Isnard, R.; Komajda, M.; Lutz, M.; Meitinger, T.; Sinner, M. F; Wichmann, H.; Krawczak, M.; Ivandic, B.; Weichenhan, D.; Gelbrich, G.; El-Mokhtari, N.; Schreiber, S.; Felix, S. B; Hasenfuß, G.; Pfeufer, A.; Hübner, N.; Kääb, S.; Arbustini, E.; Rottbauer, W.; Frey, N.; Stoll, M.; and Katus, H. A European heart journal, 35: 1069–1077. April 2014.
doi   link   bibtex   abstract  
A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression. Okada, N.; Lin, C.; Ribeiro, M. C; Biton, A.; Lai, G.; He, X.; Bu, P.; Vogel, H.; Jablons, D. M; Keller, A. C; Wilkinson, J E.; He, B.; Speed, T. P; and He, L. Genes & development, 28: 438–450. March 2014.
doi   link   bibtex   abstract  
Panel of five microRNAs as potential biomarkers for the diagnosis and assessment of male infertility. Abu-Halima, M.; Hammadeh, M.; Backes, C.; Fischer, U.; Leidinger, P.; Lubbad, A. M.; Keller, A.; and Meese, E. Fertility and sterility, 102: 989–997.e1. October 2014.
doi   link   bibtex   abstract  
MicroRNA expression profiles in human testicular tissues of infertile men with different histopathologic patterns. Abu-Halima, M.; Backes, C.; Leidinger, P.; Keller, A.; Lubbad, A. M.; Hammadeh, M.; and Meese, E. Fertility and sterility, 101: 78–86.e2. January 2014.
doi   link   bibtex   abstract  
miRNAs can be generally associated with human pathologies as exemplified for miR-144. Keller, A.; Leidinger, P.; Vogel, B.; Backes, C.; ElSharawy, A.; Galata, V.; Mueller, S. C; Marquart, S.; Schrauder, M. G; Strick, R.; Bauer, A.; Wischhusen, J.; Beier, M.; Kohlhaas, J.; Katus, H. A; Hoheisel, J.; Franke, A.; Meder, B.; and Meese, E. BMC medicine, 12: 224. December 2014.
doi   link   bibtex   abstract  
Systematic permutation testing in GWAS pathway analyses: identification of genetic networks in dilated cardiomyopathy and ulcerative colitis. Backes, C.; Rühle, F.; Stoll, M.; Haas, J.; Frese, K.; Franke, A.; Lieb, W.; Wichmann, H.; Weis, T.; Kloos, W.; Lenhof, H.; Meese, E.; Katus, H.; Meder, B.; and Keller, A. BMC genomics, 15: 622. July 2014.
doi   link   bibtex   abstract  
Influence of the confounding factors age and sex on microRNA profiles from peripheral blood. Meder, B.; Backes, C.; Haas, J.; Leidinger, P.; Stähler, C.; Großmann, T.; Vogel, B.; Frese, K.; Giannitsis, E.; Katus, H. A; Meese, E.; and Keller, A. Clinical chemistry, 60: 1200–1208. September 2014.
doi   link   bibtex   abstract  
  2013 (12)
Multivariate miRNA signatures as biomarkers for non-ischaemic systolic heart failure. Vogel, B.; Keller, A.; Frese, K. S.; Leidinger, P.; Sedaghat-Hamedani, F.; Kayvanpour, E.; Kloos, W.; Backe, C.; Thanaraj, A.; Brefort, T.; Beier, M.; Hardt, S.; Meese, E.; Katus, H. A.; and Meder, B. Eur. Heart J., 34(36): 2812–2822. Sep 2013.
link   bibtex  
Intestinal Salmonella typhimurium infection leads to miR-29a induced caveolin 2 regulation. Hoeke, L.; Sharbati, J.; Pawar, K.; Keller, A.; Einspanier, R.; and Sharbati, S. PLoS ONE, 8(6): e67300. 2013.
link   bibtex  
Paleoproteomic study of the Iceman's brain tissue. Maixner, F.; Overath, T.; Linke, D.; Janko, M.; Guerriero, G.; van den Berg, B. H.; Stade, B.; Leidinger, P.; Backes, C.; Jaremek, M.; Kneissl, B.; Meder, B.; Franke, A.; Egarter-Vigl, E.; Meese, E.; Schwarz, A.; Tholey, A.; Zink, A.; and Keller, A. Cell. Mol. Life Sci., 70(19): 3709–3722. Oct 2013.
link   bibtex  
NetworkTrail–a web service for identifying and visualizing deregulated subnetworks. Stoeckel, D.; Mueller, O.; Kehl, T.; Gerasch, A.; Backes, C.; Rurainski, A.; Keller, A.; Kaufmann, M.; and Lenhof, H. P. Bioinformatics, 29(13): 1702–1703. Jul 2013.
link   bibtex  
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies. Ellinghaus, D.; Zhang, H.; Zeissig, S.; Lipinski, S.; Till, A.; Jiang, T.; Stade, B.; Bromberg, Y.; Ellinghaus, E.; Keller, A.; Rivas, M. A.; Skieceviciene, J.; Doncheva, N. T.; Liu, X.; Liu, Q.; Jiang, F.; Forster, M.; Mayr, G.; Albrecht, M.; Hasler, R.; Boehm, B. O.; Goodall, J.; Berzuini, C. R.; Lee, J.; Andersen, V.; Vogel, U.; Kupcinskas, L.; Kayser, M.; Krawczak, M.; Nikolaus, S.; Weersma, R. K.; Ponsioen, C. Y.; Sans, M.; Wijmenga, C.; Strachan, D. P.; McArdle, W. L.; Vermeire, S.; Rutgeerts, P.; Sanderson, J. D.; Mathew, C. G.; Vatn, M. H.; Wang, J.; Nothen, M. M.; Duerr, R. H.; Buning, C.; Brand, S.; Glas, J.; Winkelmann, J.; Illig, T.; Latiano, A.; Annese, V.; Halfvarson, J.; D'Amato, M.; Daly, M. J.; Nothnagel, M.; Karlsen, T. H.; Subramani, S.; Rosenstiel, P.; Schreiber, S.; Parkes, M.; and Franke, A. Gastroenterology, 145(2): 339–347. Aug 2013.
link   bibtex  
Myasthenia gravis: analysis of serum autoantibody reactivities to 1827 potential human autoantigens by protein macroarrays. Becker, A.; Ludwig, N.; Keller, A.; Tackenberg, B.; Eienbroker, C.; Oertel, W. H.; Fassbender, K.; Meese, E.; and Ruprecht, K. PLoS ONE, 8(3): e58095. 2013.
link   bibtex  
Refining diagnostic microRNA signatures by whole-miRNome kinetic analysis in acute myocardial infarction. Vogel, B.; Keller, A.; Frese, K. S.; Kloos, W.; Kayvanpour, E.; Sedaghat-Hamedani, F.; Hassel, S.; Marquart, S.; Beier, M.; Giannitis, E.; Hardt, S.; Katus, H. A.; and Meder, B. Clin. Chem., 59(2): 410–418. Feb 2013.
link   bibtex  
From next-generation sequencing alignments to accurate comparison and validation of single-nucleotide variants: the pibase software. Forster, M.; Forster, P.; Elsharawy, A.; Hemmrich, G.; Kreck, B.; Wittig, M.; Thomsen, I.; Stade, B.; Barann, M.; Ellinghaus, D.; Petersen, B. S.; May, S.; Melum, E.; Schilhabel, M. B.; Keller, A.; Schreiber, S.; Rosenstiel, P.; and Franke, A. Nucleic Acids Res., 41(1): e16. Jan 2013.
link   bibtex  
A blood based 12-miRNA signature of Alzheimer disease patients. Leidinger, P.; Backes, C.; Deutscher, S.; Schmitt, K.; Mueller, S. C; Frese, K.; Haas, J.; Ruprecht, K.; Paul, F.; Stähler, C.; Lang, C. J G; Meder, B.; Bartfai, T.; Meese, E.; and Keller, A. Genome biology, 14: R78. July 2013.
doi   link   bibtex   abstract  
A set of specific miRNAs is connected with murine and human gastric cancer. Shah, A. A.; Leidinger, P.; Backes, C.; Keller, A.; Karpinski, P.; Sasiadek, M. M; Blin, N.; and Meese, E. Genes, chromosomes & cancer, 52: 237–249. March 2013.
doi   link   bibtex   abstract  
Alterations in cardiac DNA methylation in human dilated cardiomyopathy. Haas, J.; Frese, K. S; Park, Y. J.; Keller, A.; Vogel, B.; Lindroth, A. M; Weichenhan, D.; Franke, J.; Fischer, S.; Bauer, A.; Marquart, S.; Sedaghat-Hamedani, F.; Kayvanpour, E.; Köhler, D.; Wolf, N. M; Hassel, S.; Nietsch, R.; Wieland, T.; Ehlermann, P.; Schultz, J.; Dösch, A.; Mereles, D.; Hardt, S.; Backs, J.; Hoheisel, J. D; Plass, C.; Katus, H. A; and Meder, B. EMBO molecular medicine, 5: 413–429. March 2013.
doi   link   bibtex   abstract  
Altered microRNA expression profiles of human spermatozoa in patients with different spermatogenic impairments. Abu-Halima, M.; Hammadeh, M.; Schmitt, J.; Leidinger, P.; Keller, A.; Meese, E.; and Backes, C. Fertility and sterility, 99: 1249–1255.e16. April 2013.
doi   link   bibtex   abstract  
  2012 (16)
Whole miRNome-wide differential co-expression of microRNAs. Staehler, C. F.; Keller, A.; Leidinger, P.; Backes, C.; Chandran, A.; Wischhusen, J.; Meder, B.; and Meese, E. Genomics Proteomics Bioinformatics, 10(5): 285–294. Oct 2012.
link   bibtex  
Improving mapping and SNP-calling performance in multiplexed targeted next-generation sequencing. Elsharawy, A.; Forster, M.; Schracke, N.; Keller, A.; Thomsen, I.; Petersen, B. S.; Stade, B.; Stahler, P.; Schreiber, S.; Rosenstiel, P.; and Franke, A. BMC Genomics, 13: 417. 2012.
link   bibtex  
Treatment-independent miRNA signature in blood of Wilms tumor patients. Schmitt, J.; Backes, C.; Nourkami-Tutdibi, N.; Leidinger, P.; Deutscher, S.; Beier, M.; Gessler, M.; Graf, N.; Lenhof, H. P.; Keller, A.; and Meese, E. BMC Genomics, 13: 379. 2012.
link   bibtex  
GAS41 amplification results in overexpression of a new spindle pole protein. Schmitt, J.; Fischer, U.; Heisel, S.; Strickfaden, H.; Backes, C.; Ruggieri, A.; Keller, A.; Chang, P.; and Meese, E. Genes Chromosomes Cancer, 51(9): 868–880. Sep 2012.
link   bibtex  
Genome-wide gene amplification during differentiation of neural progenitor cells in vitro. Fischer, U.; Keller, A.; Voss, M.; Backes, C.; Welter, C.; and Meese, E. PLoS ONE, 7(5): e37422. 2012.
link   bibtex  
Genome-wide miRNA signatures of human longevity. ElSharawy, A.; Keller, A.; Flachsbart, F.; Wendschlag, A.; Jacobs, G.; Kefer, N.; Brefort, T.; Leidinger, P.; Backes, C.; Meese, E.; Schreiber, S.; Rosenstiel, P.; Franke, A.; and Nebel, A. Aging Cell, 11(4): 607–616. Aug 2012.
link   bibtex  
Diagnosis of pancreatic ductal adenocarcinoma and chronic pancreatitis by measurement of microRNA abundance in blood and tissue. Bauer, A. S.; Keller, A.; Costello, E.; Greenhalf, W.; Bier, M.; Borries, A.; Beier, M.; Neoptolemos, J.; Buchler, M.; Werner, J.; Giese, N.; and Hoheisel, J. D. PLoS ONE, 7(4): e34151. 2012.
link   bibtex  
MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors. Jiao, L. R.; Frampton, A. E.; Jacob, J.; Pellegrino, L.; Krell, J.; Giamas, G.; Tsim, N.; Vlavianos, P.; Cohen, P.; Ahmad, R.; Keller, A.; Habib, N. A.; Stebbing, J.; and Castellano, L. PLoS ONE, 7(2): e32068. 2012.
link   bibtex  
Is there a general autoantibody signature for cancer?. Ludwig, N.; Keller, A.; Leidinger, P.; Harz, C.; Backes, C.; Lenhof, H. P.; and Meese, E. Eur. J. Cancer, 48(15): 2451–2461. Oct 2012.
link   bibtex  
Multicenter study identified molecular blood-born protein signatures for Wilms Tumor. Schmitt, J.; Heisel, S.; Keller, A.; Leidinger, P.; Ludwig, N.; Habel, N.; Furtwangler, R.; Nourkami-Tutdibi, N.; Wegert, J.; Grundy, P.; Gessler, M.; Graf, N.; Lenhof, H. P.; and Meese, E. Int. J. Cancer, 131(3): 673–682. Aug 2012.
link   bibtex  
Quantification of collateral artery growth by automated fluorescent microsphere perfusion. Meder, B.; Bergmann, C. E.; Keller, A.; Just, S.; Katus, H. A.; Hoefer, I. E.; and Buschmann, I. R. Int. J. Cardiol., 161(2): 88–92. Nov 2012.
link   bibtex  
MicroRNA expression changes after lung cancer resection: a follow-up study. Leidinger, P.; Keller, A.; Backes, C.; Huwer, H.; and Meese, E. RNA Biol, 9(6): 900–910. Jun 2012.
link   bibtex  
Altered miRNA expression patterns in Tff2 knock-out mice correlate with cellular pathways of neoplastic development and caloric metabolism. Shah, A. A.; Leidinger, P.; Keller, A.; Wendschlag, A.; Meese, E.; and Blin, N. International journal of molecular medicine, 29: 637–643. April 2012.
doi   link   bibtex   abstract  
An integer linear programming approach for finding deregulated subgraphs in regulatory networks. Backes, C.; Rurainski, A.; Klau, G. W; Müller, O.; Stöckel, D.; Gerasch, A.; Küntzer, J.; Maisel, D.; Ludwig, N.; Hein, M.; Keller, A.; Burtscher, H.; Kaufmann, M.; Meese, E.; and Lenhof, H. Nucleic acids research, 40: e43. March 2012.
doi   link   bibtex   abstract  
New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing. Keller, A.; Graefen, A.; Ball, M.; Matzas, M.; Boisguerin, V.; Maixner, F.; Leidinger, P.; Backes, C.; Khairat, R.; Forster, M.; Stade, B.; Franke, A.; Mayer, J.; Spangler, J.; McLaughlin, S.; Shah, M.; Lee, C.; Harkins, T. T; Sartori, A.; Moreno-Estrada, A.; Henn, B.; Sikora, M.; Semino, O.; Chiaroni, J.; Rootsi, S.; Myres, N. M; Cabrera, V. M; Underhill, P. A; Bustamante, C. D; Vigl, E. E.; Samadelli, M.; Cipollini, G.; Haas, J.; Katus, H.; O'Connor, B. D; Carlson, M. R J; Meder, B.; Blin, N.; Meese, E.; Pusch, C. M; and Zink, A. Nature communications, 3: 698. February 2012.
doi   link   bibtex   abstract  
miRTrail–a comprehensive webserver for analyzing gene and miRNA patterns to enhance the understanding of regulatory mechanisms in diseases. Laczny, C.; Leidinger, P.; Haas, J.; Ludwig, N.; Backes, C.; Gerasch, A.; Kaufmann, M.; Vogel, B.; Katus, H. A; Meder, B.; Stähler, C.; Meese, E.; Lenhof, H.; and Keller, A. BMC bioinformatics, 13: 36. February 2012.
doi   link   bibtex   abstract  
  2011 (16)
Autoantibody signature differentiates Wilms tumor patients from neuroblastoma patients. Schmitt, J.; Keller, A.; Nourkami-Tutdibi, N.; Heisel, S.; Habel, N.; Leidinger, P.; Ludwig, N.; Gessler, M.; Graf, N.; Berthold, F.; Lenhof, H. P.; and Meese, E. PLoS ONE, 6(12): e28951. 2011.
link   bibtex  
Next-generation sequencing identifies novel microRNAs in peripheral blood of lung cancer patients. Keller, A.; Backes, C.; Leidinger, P.; Kefer, N.; Boisguerin, V.; Barbacioru, C.; Vogel, B.; Matzas, M.; Huwer, H.; Katus, H. A.; Stahler, C.; Meder, B.; and Meese, E. Mol. Biosyst., 7(12): 3187–3199. Dec 2011.
link   bibtex  
Protein kinase D2 controls cardiac valve formation in zebrafish by regulating histone deacetylase 5 activity. Just, S.; Berger, I. M.; Meder, B.; Backs, J.; Keller, A.; Marquart, S.; Frese, K.; Patzel, E.; Rauch, G. J.; Katus, H. A.; and Rottbauer, W. Circulation, 124(3): 324–334. Jul 2011.
link   bibtex  
Identification of novel SNPs in glioblastoma using targeted resequencing. Keller, A.; Harz, C.; Matzas, M.; Meder, B.; Katus, H. A.; Ludwig, N.; Fischer, U.; and Meese, E. PLoS ONE, 6(6): e18158. 2011.
link   bibtex  
Transcriptome analysis by GeneTrail revealed regulation of functional categories in response to alterations of iron homeostasis in Arabidopsis thaliana. Schuler, M.; Keller, A.; Backes, C.; Philippar, K.; Lenhof, H. P.; and Bauer, P. BMC Plant Biol., 11: 87. 2011.
link   bibtex  
Stable serum miRNA profiles as potential tool for non-invasive lung cancer diagnosis. Keller, A.; Leidinger, P.; Gislefoss, R.; Haugen, A.; Langseth, H.; Staehler, P.; Lenhof, H. P.; and Meese, E. RNA Biol., 8(3): 506–516. 2011.
link   bibtex  
Profound differences of microRNA expression patterns in hepatocytes and hepatoma cell lines commonly used in hepatitis C virus studies. Ehrhardt, M.; Leidinger, P.; Keller, A.; Baumert, T.; Diez, J.; Meese, E.; and Meyerhans, A. Hepatology, 54(3): 1112–1113. Sep 2011.
link   bibtex  
Specific peripheral miRNA profiles for distinguishing lung cancer from COPD. Leidinger, P.; Keller, A.; Borries, A.; Huwer, H.; Rohling, M.; Huebers, J.; Lenhof, H. P.; and Meese, E. Lung Cancer, 74(1): 41–47. Oct 2011.
link   bibtex  
The intestinal factor Tff3 and a miRNA network regulate murine caloric metabolism. Shah, A. A.; Leidinger, P.; Keller, A.; Wendschlag, A.; Backes, C.; Baus-Loncar, M.; Meese, E.; and Blin, N. RNA Biol., 8(1): 77–81. 2011.
link   bibtex  
Novel immunogenic antigens increase classification accuracy in meningioma to 93.84%. Ludwig, N.; Keller, A.; Heisel, S.; Leidinger, P.; Rheinheimer, S.; Andres, C.; Stephan, B.; Steudel, W. I.; Donauer, E.; Graf, N.; Burgeth, B.; Weickert, J.; Lenhof, H. P.; and Meese, E. Int. J. Cancer, 128(6): 1493–1501. Mar 2011.
link   bibtex  
MicroRNAs - Important Molecules in Lung Cancer Research. Leidinger, P.; Keller, A.; and Meese, E. Front. Genet., 2: 104. 2011.
link   bibtex  
Immunogenicity of autoantigens. Backes, C.; Ludwig, N.; Leidinger, P.; Harz, C.; Hoffmann, J.; Keller, A.; Meese, E.; and Lenhof, H. P. BMC Genomics, 12: 340. 2011.
link   bibtex  
A specific miRNA signature in the peripheral blood of glioblastoma patients. Roth, P.; Wischhusen, J.; Happold, C.; Chandran, P A.; Hofer, S.; Eisele, G.; Weller, M.; and Keller, A. Journal of neurochemistry, 118: 449–457. August 2011.
doi   link   bibtex   abstract  
Toward the blood-borne miRNome of human diseases. Keller, A.; Leidinger, P.; Bauer, A.; Elsharawy, A.; Haas, J.; Backes, C.; Wendschlag, A.; Giese, N.; Tjaden, C.; Ott, K.; Werner, J.; Hackert, T.; Ruprecht, K.; Huwer, H.; Huebers, J.; Jacobs, G.; Rosenstiel, P.; Dommisch, H.; Schaefer, A.; Müller-Quernheim, J.; Wullich, B.; Keck, B.; Graf, N.; Reichrath, J.; Vogel, B.; Nebel, A.; Jager, S. U; Staehler, P.; Amarantos, I.; Boisguerin, V.; Staehler, C.; Beier, M.; Scheffler, M.; Büchler, M. W; Wischhusen, J.; Haeusler, S. F M; Dietl, J.; Hofmann, S.; Lenhof, H.; Schreiber, S.; Katus, H. A; Rottbauer, W.; Meder, B.; Hoheisel, J. D; Franke, A.; and Meese, E. Nature methods, 8: 841–843. September 2011.
doi   link   bibtex   abstract  
MicroRNA signatures in total peripheral blood as novel biomarkers for acute myocardial infarction. Meder, B.; Keller, A.; Vogel, B.; Haas, J.; Sedaghat-Hamedani, F.; Kayvanpour, E.; Just, S.; Borries, A.; Rudloff, J.; Leidinger, P.; Meese, E.; Katus, H. A; and Rottbauer, W. Basic research in cardiology, 106: 13–23. January 2011.
doi   link   bibtex   abstract  
Targeted next-generation sequencing for the molecular genetic diagnostics of cardiomyopathies. Meder, B.; Haas, J.; Keller, A.; Heid, C.; Just, S.; Borries, A.; Boisguerin, V.; Scharfenberger-Schmeer, M.; Stähler, P.; Beier, M.; Weichenhan, D.; Strom, T. M; Pfeufer, A.; Korn, B.; Katus, H. A; and Rottbauer, W. Circulation. Cardiovascular genetics, 4: 110–122. April 2011.
doi   link   bibtex   abstract  
  2010 (9)
High-fidelity gene synthesis by retrieval of sequence-verified DNA identified using high-throughput pyrosequencing. Matzas, M.; Staehler, P. F.; Kefer, N.; Siebelt, N.; Boisguerin, V.; Leonard, J. T.; Keller, A.; Stahler, C. F.; Haberle, P.; Gharizadeh, B.; Babrzadeh, F.; and Church, G. M. Nat. Biotechnol., 28(12): 1291–1294. Dec 2010.
link   bibtex  
Protein- versus peptide fractionation in the first dimension of two-dimensional high-performance liquid chromatography-matrix-assisted laser desorption/ionization tandem mass spectrometry for qualitative proteome analysis of tissue samples. Melchior, K.; Tholey, A.; Heisel, S.; Keller, A.; Lenhof, H. P.; Meese, E.; and Huber, C. G. J. Chromatogr. A, 1217(40): 6159–6168. Oct 2010.
link   bibtex  
Whole blood-derived miRNA profiles as potential new tools for ovarian cancer screening. Hausler, S. F.; Keller, A.; Chandran, P. A.; Ziegler, K.; Zipp, K.; Heuer, S.; Krockenberger, M.; Engel, J. B.; Honig, A.; Scheffler, M.; Dietl, J.; and Wischhusen, J. Br. J. Cancer, 103(5): 693–700. Aug 2010.
link   bibtex  
High-throughput miRNA profiling of human melanoma blood samples. Leidinger, P.; Keller, A.; Borries, A.; Reichrath, J.; Rass, K.; Jager, S. U.; Lenhof, H. P.; and Meese, E. BMC Cancer, 10: 262. 2010.
link   bibtex  
Deciphering the porcine intestinal microRNA transcriptome. Sharbati, S.; Friedlander, M. R.; Sharbati, J.; Hoeke, L.; Chen, W.; Keller, A.; Stahler, P. F.; Rajewsky, N.; and Einspanier, R. BMC Genomics, 11: 275. 2010.
link   bibtex  
Reduced cortisol levels in cerebrospinal fluid and differential distribution of 11beta-hydroxysteroid dehydrogenases in multiple sclerosis: implications for lesion pathogenesis. Heidbrink, C.; Hausler, S. F.; Buttmann, M.; Ossadnik, M.; Strik, H. M.; Keller, A.; Buck, D.; Verbraak, E.; van Meurs, M.; Krockenberger, M.; Mehling, M.; Mittelbronn, M.; Laman, J. D.; Wiendl, H.; and Wischhusen, J. Brain Behav. Immun., 24(6): 975–984. Aug 2010.
link   bibtex  
Identification of lung cancer with high sensitivity and specificity by blood testing. Leidinger, P.; Keller, A.; Heisel, S.; Ludwig, N.; Rheinheimer, S.; Klein, V.; Andres, C.; Staratschek-Jox, A.; Wolf, J.; Stoelben, E.; Stephan, B.; Stehle, I.; Hamacher, J.; Huwer, H.; Lenhof, H. P.; and Meese, E. Respir. Res., 11: 18. 2010.
link   bibtex  
A dictionary on microRNAs and their putative target pathways. Backes, C.; Meese, E.; Lenhof, H.; and Keller, A. Nucleic acids research, 38: 4476–4486. July 2010.
doi   link   bibtex   abstract  
Amplicons on chromosome 12q13-21 in glioblastoma recurrences. Fischer, U.; Leidinger, P.; Keller, A.; Folarin, A.; Ketter, R.; Graf, N.; Lenhof, H.; and Meese, E. International journal of cancer, 126: 2594–2602. June 2010.
doi   link   bibtex   abstract  
  2009 (10)
Improving seroreactivity-based detection of glioma. Ludwig, N.; Keller, A.; Heisel, S.; Leidinger, P.; Klein, V.; Rheinheimer, S.; Andres, C. U.; Stephan, B.; Steudel, W. I.; Graf, N. M.; Burgeth, B.; Weickert, J.; Lenhof, H. P.; and Meese, E. Neoplasia, 11(12): 1383–1389. Dec 2009.
link   bibtex  
Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls. Keller, A.; Leidinger, P.; Lange, J.; Borries, A.; Schroers, H.; Scheffler, M.; Lenhof, H. P.; Ruprecht, K.; and Meese, E. PLoS ONE, 4(10): e7440. 2009.
link   bibtex  
miRNAs in lung cancer - studying complex fingerprints in patient's blood cells by microarray experiments. Keller, A.; Leidinger, P.; Borries, A.; Wendschlag, A.; Wucherpfennig, F.; Scheffler, M.; Huwer, H.; Lenhof, H. P.; and Meese, E. BMC Cancer, 9: 353. 2009.
link   bibtex  
Proteomic study of human glioblastoma multiforme tissue employing complementary two-dimensional liquid chromatography- and mass spectrometry-based approaches. Melchior, K.; Tholey, A.; Heisel, S.; Keller, A.; Lenhof, H. P.; Meese, E.; and Huber, C. G. J. Proteome Res., 8(10): 4604–4614. Oct 2009.
link   bibtex  
Novel autoantigens immunogenic in COPD patients. Leidinger, P.; Keller, A.; Heisel, S.; Ludwig, N.; Rheinheimer, S.; Klein, V.; Andres, C.; Hamacher, J.; Huwer, H.; Stephan, B.; Stehle, I.; Lenhof, H. P.; and Meese, E. Respir. Res., 10: 20. 2009.
link   bibtex  
Staphylococcus aureus ClpC ATPase is a late growth phase effector of metabolism and persistence. Chatterjee, I.; Schmitt, S.; Batzilla, C. F.; Engelmann, S.; Keller, A.; Ring, M. W.; Kautenburger, R.; Ziebuhr, W.; Hecker, M.; Preissner, K. T.; Bischoff, M.; Proctor, R. A.; Beck, H. P.; Lenhof, H. P.; Somerville, G. A.; and Herrmann, M. Proteomics, 9(5): 1152–1176. Mar 2009.
link   bibtex  
Genome wide expression profiling identifies specific deregulated pathways in meningioma. Keller, A.; Ludwig, N.; Backes, C.; Romeike, B. F.; Comtesse, N.; Henn, W.; Steudel, W. I.; Mawrin, C.; Lenhof, H. P.; and Meese, E. Int. J. Cancer, 124(2): 346–351. Jan 2009.
link   bibtex  
Combining gene expression signatures and autoantibody profiles in human meningioma. Keller, A.; Ludwig, N.; Comtesse, N.; Henn, W.; Steudel, W. I.; Lenhof, H. P.; and Meese, E. Gene Ther., 16(2): 184–189. Feb 2009.
link   bibtex  
Large-scale antibody profiling of human blood sera: The future of molecular diagnosis. Keller, A.; Ludwig, N.; Heisel, S.; Leidinger, P.; Andres, C.; Steudel, W.; Huwer, H.; Burgeth, B.; Hein, M.; Weickert, J.; Meese, E.; and Lenhof, H. Informatik-Spektrum, 32(4): 332-338. 2009.
Large-scale antibody profiling of human blood sera: The future of molecular diagnosis [link]Paper   doi   link   bibtex  
A novel algorithm for detecting differentially regulated paths based on gene set enrichment analysis. Keller, A.; Backes, C.; Gerasch, A.; Kaufmann, M.; Kohlbacher, O.; Meese, E.; and Lenhof, H. Bioinformatics (Oxford, England), 25: 2787–2794. November 2009.
doi   link   bibtex   abstract  
  2008 (5)
GeneTrailExpress: a web-based pipeline for the statistical evaluation of microarray experiments. Keller, A.; Backes, C.; Al-Awadhi, M.; Gerasch, A.; Kuntzer, J.; Kohlbacher, O.; Kaufmann, M.; and Lenhof, H. P. BMC Bioinformatics, 9: 552. 2008.
link   bibtex  
Pattern of serum autoantibodies allows accurate distinction between a tumor and pathologies of the same organ. Ludwig, N.; Keller, A.; Comtesse, N.; Rheinheimer, S.; Pallasch, C.; Fischer, U.; Fassbender, K.; Steudel, W. I.; Lenhof, H. P.; and Meese, E. Clin. Cancer Res., 14(15): 4767–4774. Aug 2008.
link   bibtex  
Toward an early diagnosis of lung cancer: an autoantibody signature for squamous cell lung carcinoma. Leidinger, P.; Keller, A.; Ludwig, N.; Rheinheimer, S.; Hamacher, J.; Huwer, H.; Stehle, I.; Lenhof, H. P.; and Meese, E. Int. J. Cancer, 123(7): 1631–1636. Oct 2008.
link   bibtex  
Increased seroreactivity to glioma-expressed antigen 2 in brain tumor patients under radiation. Heisel, S. M.; Ketter, R.; Keller, A.; Klein, V.; Pallasch, C. P.; Lenhof, H. P.; and Meese, E. PLoS ONE, 3(5): e2164. 2008.
link   bibtex  
A different view on DNA amplifications indicates frequent, highly complex, and stable amplicons on 12q13-21 in glioma. Fischer, U.; Keller, A.; Leidinger, P.; Deutscher, S.; Heisel, S.; Urbschat, S.; Lenhof, H.; and Meese, E. Molecular cancer research : MCR, 6: 576–584. April 2008.
doi   link   bibtex   abstract  
  2007 (5)
Computation of significance scores of unweighted Gene Set Enrichment Analyses. Keller, A.; Backes, C.; and Lenhof, H. P. BMC Bioinformatics, 8: 290. 2007.
link   bibtex  
Evidence for the mode of action of the highly cytotoxic Streptomyces polyketide kendomycin. Elnakady, Y. A.; Rohde, M.; Sasse, F.; Backes, C.; Keller, A.; Lenhof, H. P.; Weissman, K. J.; and Mueller, R. Chembiochem, 8(11): 1261–1272. Jul 2007.
link   bibtex  
GeneTrail–advanced gene set enrichment analysis. Backes, C.; Keller, A.; Kuentzer, J.; Kneissl, B.; Comtesse, N.; Elnakady, Y. A.; Mueller, R.; Meese, E.; and Lenhof, H. P. Nucleic Acids Res., 35: W186–192. Jul 2007.
link   bibtex  
SePaCS–a web-based application for classification of seroreactivity profiles. Keller, A.; Comtesse, N.; Ludwig, N.; Meese, E.; and Lenhof, H. P. Nucleic Acids Res., 35: W683–687. Jul 2007.
link   bibtex  
Frequent overexpression of the genes FXR1, CLAPM1 and EIF4G located on amplicon 3q26-27 in squamous cell carcinoma of the lung. Comtesse, N.; Keller, A.; Diesinger, I.; Bauer, C.; Kayser, K.; Huwer, H.; Lenhof, H. P.; and Meese, E. Int. J. Cancer, 120(12): 2538–2544. Jun 2007.
link   bibtex  
  2006 (1)
A minimally invasive multiple marker approach allows highly efficient detection of meningioma tumors. Keller, A.; Ludwig, N.; Comtesse, N.; Hildebrandt, A.; Meese, E.; and Lenhof, H. BMC bioinformatics, 7: 539. December 2006.
doi   link   bibtex   abstract  
  2005 (1)
Complex humoral immune response against a benign tumor: frequent antibody response against specific antigens as diagnostic targets. Comtesse, N.; Zippel, A.; Walle, S.; Monz, D.; Backes, C.; Fischer, U.; Mayer, J.; Ludwig, N.; Hildebrandt, A.; Keller, A.; Steudel, W. I.; Lenhof, H. P.; and Meese, E. Proc. Natl. Acad. Sci. U.S.A., 102(27): 9601–9606. Jul 2005.
link   bibtex